Best HealthTech Companies in Burlington, United States
The 39 best HealthTech companies in Burlington, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: LightForce.
Our analysis of 305 HealthTech companies
$32.1b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best HealthTech companies in Burlington
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | LightForce Care and treatment planning tools and software for orthodontists | $144M | 37 mo ago | Series D | Lou Shuman Co-Founder | 2015 | Craft CMSPHPUbuntu+26 | — | — |
| 2 | HealthEdge Provider of a suite solutions for healthcare payer | $108M | 109 mo ago | Acquired | Stephen Krupa Chief Executive Officer | 2004 | WordPressMySQLMariaDB+24 | 2 patents Insurance claim processing using semantic network-based transaction analysis | — |
| 3 | HighRoads Provider of a SaaS based suite solution for payers | $33M | 120 mo ago | Series C | — | 1999 | WordPressMySQLPHP+18 | 5 patents HR benefits data platforms and insurance plan comparison analytics for enterprises | — |
| 4 | SiPhox Health Provider of comprehensive at-home blood testing kits | $30M | 37 mo ago | Series A | Diedrik Vermeulen Co-founder and CEO | 2020 | SanitySentryZendesk+32 | — | — |
| 5 | Ametros Provider of medical funds management and settlement services | $20M | 105 mo ago | Acquired | — | 2010 | WordPressMySQLPHP+19 | 2 patents Smart home control and automation technologies for residential environments | — |
| 6 | THINKmd Point-of-care clinical assessment tool | $9M | 56 mo ago | Series A | Barry Finette Co-Founder & CEO | 2014 | — | — | — |
| 7 | Azara Healthcare Cloud-based population health management tool for hospitals | $9M | 68 mo ago | Series B | Jeff Brandes CEO | 2011 | HubSpot CMS HubApple iCloud MailSalesforce+27 | — | — |
| 8 | IHM Services SaaS based compliance and performance improvement solution | $6M | 137 mo ago | Acquired | — | 2012 | — | — | — |
| 9 | Agrify Cannabis and hemp brands delivering wellness and lifestyle experiences | $4M | 15 mo ago | Public | Raymond Chang Chairman & CEO | 2016 | WordPressMySQLPHP+34 | 5 patents Patents concentrated in electrical & electronics | — |
| 10 | Nurse-1-1 Provider of communication app for nurses | $4M | 54 mo ago | Seed | — | 2018 | TypeScriptZone.jsAngular+11 | — | — |
| 11 | OpenTempo Cloud-based workforce management and staff scheduling solutions | $4M | 121 mo ago | Acqui-Hired | — | 2013 | — | — | — |
| 12 | Patient Engagement Systems Patient engagement solutions improving healthcare outcomes, communication, and chronic disease management | $3M | 108 mo ago | Seed | — | 2006 | — | — | — |
| 13 | Aprexis Medication Therapy Management services and customizable clinical programs for patient-centered pharmacy care | $700K | 181 mo ago | Seed | Nancy Bundek Co-Founder | 2009 | — | — | — |
| 14 | Novobeing Provider of immersive wellness experiences, transforming high-stress areas into spaces of rejuvenation | $575K | 28 mo ago | Seed | Siddharth Desai Co-Founder & CEO | 2020 | Wix eCommerceWixSentry+13 | — | — |
| 15 | Formedix Clinical trial automation software and consultancy services based on CDISC standards. | $320K | 166 mo ago | Funding Raised | — | 2000 | — | — | — |
| 16 | Ascend Learning Testing & certification for healthcare, education and wellness professionals | — | — | Acquired | — | 2010 | MagentoTypeScriptGraphQL+21 | — | — |
| 17 | Azenta Provider of sample storage and management solutions | — | — | Public | Stephen Schwartz CEO & President | 1978 | WordPress Block EditorWordPressApple iCloud Mail+31 | 81 patents Large-scale cryogenic biobanking systems and sample handling devices | — |
Top 12 HealthTech companies in Burlington
#1
Public · Burlington, Massachusetts · founded 2016 · 72 employees$4.5Mraised▾
Cannabis and hemp brands delivering wellness and lifestyle experiences. The company cultivates cannabis and crafts innovative hemp products designed to enhance daily life. It offers a diverse portfolio of trusted brands, including cannabis flower, pre-rolls, THC-infused beverages, and other cannabis products.
- May 2025Post IPO$30M
- Nov 2024Post IPO$25.9M
- Aug 2024Post IPO$400K
- Jan 2022Post IPO$27.3M
#2
Series D · Burlington, Massachusetts · founded 2015 · 86 employees$144Mraised▾
Care and treatment planning tools and software for orthodontists. The company offers customized 3D printed tools and a web-based platform for orthodontists to create, adjust, and manage treatment plans for their patients.
- Aug 2023Series D$80M
- Nov 2021Series C$50M
- Sep 2020Series B$14M
#3
Series A · Burlington, Massachusetts · founded 2020 · 29 employees$29.6Mraised▾
Provider of comprehensive at-home blood testing kits. It offers biomarker panels which include hormones, metabolic markers, cardiovascular, inflammation, thyroid, liver, kidney, and nutritional status.
- Jul 2023Series A$17M
- Jan 2023Seed$12.5M
- Jul 2022Grant (prize money)$681K
- Nov 2021Seed$1.5M
#4
Acquired · Burlington, Massachusetts · founded 2004 · 501 employees$108.5Mraised▾
HealthEdge provides a suite of software products for the healthcare payer market. Suite platform HealthRules is delivered to customers via the HealthEdge Cloud or on-site deployment. The suite includes claims and benefits administration, care management, business intelligence, and portal solutions designed to empower healthcare payers to capitalize on innovations and opportunities that await them in the new healthcare economy.
- Jul 2017Venture Debt—
- 2016Series C$25M
- Feb 2015Series C$9.3M
- Sep 2014Series C$30M
#5
Seed · Burlington, Massachusetts · founded 2020 · 10 employees$575Kraised▾
Provider of immersive wellness experiences, transforming high-stress areas into spaces of rejuvenation.. Their innovative platform combines immersive virtual environments with uplifting music, meditations, and breathing techniques for enhanced self-care experiences.
- Apr 2024Grant (prize money)$25K
- Feb 2024Seed—
- Feb 2023Conventional Debt—
- Feb 2023Seed$500K
#6
Series C · Burlington, Massachusetts · founded 1999 · 87 employees$33.1Mraised▾
HighRoads, formerly known as IE-Engine offers a SaaS-based suite solution for payers. The company has offers P2 advance, a SaaS-based plan management solution, which includes data management, document generation, plan configuration, distribution, workflow, systems integration, scalability, and compliance. Using P2 Advance, payer solutions offered include account management, compliance communications, and workflow for product strategy, contracts/legal, product operations, marketing, sales, and information technology applications.
- Aug 2016Series C$2M
- May 2015Series C$3M
- Jun 2014Series C$3.7M
- Feb 2013Series C$262.5K
#7
Series B · Burlington, Massachusetts · founded 2011 · 129 employees$9.1Mraised▾
Cloud-based population health management tool for hospitals. The company provides solutions for patient health planning and management. It has features for care management, telecommunication, patient engagement, and more.
- Dec 2020PE—
- Apr 2017Series B$2.1M
- Jul 2014Series B$5.4M
- Apr 2014Conventional Debt$99K
#8
Series A · Burlington, Vermont · founded 2014 · 14 employees$9.4Mraised▾
Developer of clinical intelligence software designed to diagnose and treat patients at the clinic or community level. The company's software helps healthcare professionals to understand what the data means and track performance, enabling physicians to increase healthcare capacity, evolving healthcare delivery and collect and analyze critical public health data that will improve clinical outcomes, surveillance, and healthcare management globally.
#9
Acquired · Burlington, Massachusetts · founded 2010 · 117 employees$20Mraised▾
Provider of medical funds management and settlement services
- Nov 2017Series A$20M
#10
Seed · Burlington, Massachusetts · founded 2018 · 24 employees$3.5Mraised▾
Provider of communication app for nurses. The Nurse-1-1 for nurses application helps providers, payers, and individual registered practitioners to engage with the patients via mobile chat. It offers independent scheduling, payment transaction for the nurses and organizations for the medical chat consultation.
- Mar 2022Seed$2.3M
#11
Acquired · Burlington, Massachusetts · founded 2012 · 1 employees$6.5Mraised▾
IHM Services (acquired by Persivia in 2015) is an analytics provider that offers a SaaS-based solution focused on quality and regulatory reporting for hospitals. The company claims by transforming hospital data into actionable information help improve patient care and safety, produces predictable medical outcomes, mitigates clinical risk and improves financial performance. The company’s meaningful use and clinical reporting solutions help hospitals achieve compliance with federal P4P programs. IHM combines proprietary mapping and clinical intelligence with evidence-based guidelines.
#12
Seed · Burlington, Vermont · founded 2006 · 11 employees$2.7Mraised▾
Patient engagement solutions improving healthcare outcomes, communication, and chronic disease management. The company offers technology and services to empower patients, enhance provider-patient relationships, and optimize healthcare delivery. They focus on motivating patients to actively manage their health, particularly those with chronic conditions. Their solutions aim to improve treatment plan compliance, reduce healthcare costs, and meet industry guidelines. They provide tools for health plans to identify early-stage chronic patients and support care managers. The company's offerings enhance patient communications, clinical content, and workflow within electronic health records and population health solutions. They help clinical laboratories increase the visibility of their services and support healthcare providers in achieving clinical and financial objectives. The company's solutions are designed to support value-based care models and improve overall patient satisfaction with health services.
- Sep 2017Grant (prize money)$150K
- May 2015Angel$250.6K
- Feb 2014Seed$259K
- Sep 2011Seed$350K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of HealthTech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health is moving in the United States
A read on the academic research around Digital Health — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 8,843 United States-affiliated papers.
- Design Intelligence421
- Harvard University383
- Johns Hopkins University295
- University of North Carolina at Chapel Hill206
- University of Washington173
- Health care9→240
- Wearable computer6→129
- Health informatics25→140
- Remote patient monitoring11→76
- Informatics10→60
- Health care36→766
- Health informatics113→495
- Psychological intervention20→320
- Public health34→290
- Intervention (counseling)5→193
- Health care98→1170
- Health informatics213→712
- Public health73→525
- Psychological intervention26→368
- Health administration110→363
Where digital health is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing medical devices patents in the United States
United States medical devices patent filing is accelerating — 666,693 filings from 8,000 assignees (2016–2025), led by Covidien, Boston Scient Scimed, Medtronic; annual filings 63466→63610.
- Covidien29348
- Boston Scient Scimed24762
- Medtronic22394
- Becton Dickinson18249
- Procter & Gamble16178
- Ethicon ENDO Surgery13723
- Kimberly Clark12440
- Ethicon11761