Best HealthTech Companies in California, United States
The 5227 best HealthTech companies in California, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Rad Partners.
Our analysis of 305 HealthTech companies
$32.1b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best HealthTech companies in California
| # | Company | Disclosed funding | Last round | Employees | Founder | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|
| 1 | HeartFlow 🦄 Provides cardiovascular diagnostic support using analytics 87AI top 15%Funding top 18%News top 23%Patents top 25% All 13 signals ▾AItop 15% Fundingtop 18% Newstop 23% Patentstop 25% Growthtop 27% Markettop 30% Moattop 30% Techtop 32% Innovationtop 35% Fin. healthtop 45% Globaltop 47% Talentbottom 49% Partnersbottom 35% AI: Holds AI/ML patents (G06N-family CPC) Funding: Raised $838M across 13 rounds · 13 rounds over 17 yrs (0.8/yr) rank vs industry peers · Fliar Intelligence Index 87/100 | $838M | 14 mo ago | 363 363 → 841 (+132%) · sector median +23% | John Farquhar President and Chief Executive Officer | 1,118 patents Patents concentrated in health & consumer products | — |
| 2 | Eikon 🦄 Protein tracking and measuring tool for drug discovery 60Funding top 14%News top 28%Moat top 28%Market top 38% All 10 signals ▾Fundingtop 14% Newstop 28% Moattop 28% Markettop 38% Growthtop 40% Techtop 43% Talenttop 44% Globalbottom 42% Patentsbottom 38% Innovationbottom 36% Funding: Raised $668M across 4 rounds · 4 rounds over 5 yrs (0.8/yr) News: 8 BI events in 12 mo (of 23 tracked, 7 types) · +14% YoY rank vs industry peers · Fliar Intelligence Index 60/100 | $668M | 16 mo ago | 331 | Robert Tjian Co-Founder | 9 patents Automated vehicle intrusion barriers for rapid security deployment | — |
| 3 | Innovaccer 🦄 Developer of healthcare data platforms and artificial intelligence agent software 93Funding top 23%Tech top 25%AI top 25%Moat top 25% All 13 signals ▾Fundingtop 23% Techtop 25% AItop 25% Moattop 25% Markettop 26% Fin. healthtop 28% Talenttop 28% Innovationtop 29% Patentstop 32% Growthtop 33% Producttop 38% Globaltop 42% Newsbottom 24% Funding: Raised $379M across 8 rounds · 8 rounds over 11 yrs (0.7/yr) Tech: 43 technologies across 6/8 capability areas · Cloud: Amazon S3, Amazon Ses rank vs industry peers · Fliar Intelligence Index 93/100 | $379M | 17 mo ago | 1,003 1,003 → 1,712 (+71%) · sector median +23% | Abhinav Shashank Co-Founder & CEO | 30 patents Integrating and analyzing de‑identified healthcare data across clouds for clinical decision support | 1 partnership |
| 4 | Exo Developer of point of care ultrasound ecosystem with AI-powered diagnostic and workflow tools 72Funding top 15%Talent top 28%AI top 30%Tech top 31% All 10 signals ▾Fundingtop 15% Talenttop 28% AItop 30% Techtop 31% Moattop 31% Growthtop 45% Markettop 46% Innovationbottom 43% Patentsbottom 42% Globalbottom 39% Funding: Raised $346M across 10 rounds · 10 rounds over 7 yrs (1.4/yr) Talent: 3 named leaders on record · 3 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 72/100 | $346M | 12 mo ago | 152 152 → 185 (+22%) · sector median +23% | Sandeep Akkaraju CEO/Founder | 10 patents Patents concentrated in electrical & electronics | — |
| 5 | Visby Medical 🦄 Provider of at-home tests for sexually transmitted infections with telehealth 69Funding top 13%Growth top 13%Moat top 26%Product top 32% All 10 signals ▾Fundingtop 13% Growthtop 13% Moattop 26% Producttop 32% Markettop 38% Techbottom 49% Talentbottom 49% Globalbottom 39% Newsbottom 21% Customersbottom 1% Funding: Raised $331M across 11 rounds · 11 rounds over 11 yrs (1.0/yr) Growth: Headcount 80 → 251 (+214%) across vintages · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 69/100 | $331M | 12 mo ago | 251 | Adam Zerda Founder & CEO | — | — |
| 6 | Earlens Corporation Provider of hearing aids for people with less hearing power 62Funding top 17%Moat top 19%Tech top 27%Patents top 31% All 10 signals ▾Fundingtop 17% Moattop 19% Techtop 27% Patentstop 31% Innovationtop 36% Talenttop 38% Markettop 49% Globalbottom 47% Growthbottom 39% Newsbottom 21% Funding: Raised $326M across 15 rounds · 15 rounds over 16 yrs (0.9/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 362 patents rank vs industry peers · Fliar Intelligence Index 62/100 | $326M | 15 mo ago | 129 129 → 111 (-14%) · sector median +23% | Rodney Perkins Founder | 362 patents Advanced contact hearing aids and acoustic signal processing for ear canal devices | 1 job opening |
| 7 | Twin Health Provider of personalized metabolic health programs 42Funding top 26%Talent top 38%Market top 42%Global top 42% All 7 signals ▾Fundingtop 26% Talenttop 38% Markettop 42% Globaltop 42% Moatbottom 43% Fin. healthbottom 36% Growthbottom 30% Funding: Raised $272M across 4 rounds · 4 rounds over 6 yrs (0.7/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 42/100 | $272M | 13 mo ago | 209 | Maluk Mohamed Co-Founder | — | — |
| 8 | Evidation Real-world health data insights for better healthcare decisions and research 72Funding top 20%Customers top 27%Tech top 31%Moat top 31% All 10 signals ▾Fundingtop 20% Customerstop 27% Techtop 31% Moattop 31% Producttop 36% Talenttop 38% Growthtop 41% Markettop 43% Globalbottom 37% Newsbottom 22% Funding: Raised $259M across 7 rounds · 7 rounds over 11 yrs (0.6/yr) Customers: App rating 4.2★ (20,400 reviews) · Review volume +3% in 6 mo rank vs industry peers · Fliar Intelligence Index 72/100 | $259M | 15 mo ago | 196 196 → 101 (-48%) · sector median +23% | Christine Lemke Co-founder | — | — |
| 9 | Chai Discovery 🦄 Developer of artificial intelligence models for de novo molecular design 72Funding top 14%Talent top 28%AI top 30%Moat top 32% All 7 signals ▾Fundingtop 14% Talenttop 28% AItop 30% Moattop 32% Markettop 48% Globalbottom 48% Techbottom 42% Funding: Raised $230M across 3 rounds · 3 rounds over 2 yrs (1.5/yr) Talent: 4 named leaders on record · 4 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 72/100 | $230M | 6 mo ago | — | Joshua Meier Co-Founder | — | 1 partnership |
| 10 | Neuron23 AI-based drug discovery model for researchers 80Growth top 13%Funding top 18%Patents top 21%Moat top 21% All 10 signals ▾Growthtop 13% Fundingtop 18% Patentstop 21% Moattop 21% Innovationtop 23% AItop 45% Talentbottom 49% Globalbottom 40% Marketbottom 38% Newsbottom 18% Growth: Headcount 12 → 29 (+142%) across vintages · Fresh capital in last 24 mo Funding: Raised $214M across 4 rounds · 4 rounds over 6 yrs (0.7/yr) rank vs industry peers · Fliar Intelligence Index 80/100 | $214M | 11 mo ago | 29 29 → 28 (-3%) · sector median +23% | Adam Knight Founder & CBO | 49 patents LRRK2 kinase inhibitor therapeutics and biomarkers for Parkinson's disease treatment | 1 partnership |
| 11 | Iambic Therapeutics Provider of AI-driven drug discovery platform for the treatment of cancer 60Funding top 15%AI top 26%Moat top 31%Talent top 38% All 9 signals ▾Fundingtop 15% AItop 26% Moattop 31% Talenttop 38% Growthtop 45% Marketbottom 43% Newsbottom 43% Techbottom 40% Globalbottom 39% Funding: Raised $206M across 5 rounds · 5 rounds over 5 yrs (1.0/yr) AI: Classified as an AI company · Product described with: ai driven, ai-driven rank vs industry peers · Fliar Intelligence Index 60/100 | $206M | 2 mo ago | 50 | Fred Manby Co-Founder & CTO | — | — |
| 12 | Hims Online platform offering telehealth services for men's wellness 84Customers top 7%Tech top 16%Market top 19%Funding top 20% All 12 signals ▾Customerstop 7% Techtop 16% Markettop 19% Fundingtop 20% Producttop 24% Talenttop 28% Innovationtop 33% Fin. healthtop 36% Moattop 48% Growthbottom 47% Globalbottom 39% Newsbottom 21% Customers: App rating 4.6★ (6,574 reviews) Tech: 48 technologies across 7/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 rank vs industry peers · Fliar Intelligence Index 84/100 | $197M | 13 mo ago | 1,046 1,046 → 2,059 (+97%) · sector median +23% | Joe Spector Co-Founder | — | 2 launchs |
| 13 | Strava 🦄 Provider of application for tracking, analyzing, and sharing fitness activities 89Customers top 14%Market top 19%Tech top 20%Funding top 24% All 12 signals ▾Customerstop 14% Markettop 19% Techtop 20% Fundingtop 24% Moattop 25% Producttop 27% Growthtop 31% Patentstop 35% Innovationtop 38% Talenttop 38% Globaltop 42% Newstop 45% Customers: Play-Store rating 4.60★ across 1,123,622 ratings (1 apps) · Review volume +4% in 6 mo Market: 290 employees (top 13% of HealthTech) · Top-5,000 web property rank vs industry peers · Fliar Intelligence Index 89/100 | $180M | 12 mo ago | 290 | Davis Kitchel Co-Founder | 70 patents Sports activity analytics and geospatial mapping for fitness tracking and route optimization | 1 launch · 2 partnerships |
| 14 | BrightInsight Provider of digital health solutions for clinical trials 57Funding top 18%Moat top 31%Growth top 35%Market top 50% All 8 signals ▾Fundingtop 18% Moattop 31% Growthtop 35% Markettop 50% Techbottom 49% Talentbottom 49% Newsbottom 43% Globalbottom 37% Funding: Raised $166M across 4 rounds · 4 rounds over 7 yrs (0.6/yr) Moat: Editorial + unicorn rating 8/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 57/100 | $166M | 4 mo ago | 165 165 → 145 (-12%) · sector median +23% | Frederik Smits Co-founder & Managing Director | — | — |
| 15 | Cala Health Developer of a wearable non-invasive neuromodulation device 60Funding top 17%Product top 21%Innovation top 22%Patents top 26% All 11 signals ▾Fundingtop 17% Producttop 21% Innovationtop 22% Patentstop 26% Moattop 26% Talenttop 38% Techtop 46% Growthbottom 44% Marketbottom 43% Globalbottom 42% Newsbottom 21% Funding: Raised $157M across 7 rounds · 7 rounds over 13 yrs (0.5/yr) Product: 6 distinct product lines · Company stage: Series D rank vs industry peers · Fliar Intelligence Index 60/100 | $157M | 1 mo ago | 50 50 → 122 (+144%) · sector median +23% | Kate Rosenbluth Founder and Co-President | 243 patents Wearable peripheral nerve stimulation devices for tremor, movement and musculoskeletal disorder therapy | 1 award |
| 16 | Qualified Health Provider of an enterprise AI platform for healthcare systems 57Funding top 18%AI top 20%Talent top 38%Tech bottom 44% All 6 signals ▾Fundingtop 18% AItop 20% Talenttop 38% Techbottom 44% Marketbottom 40% Globalbottom 33% Funding: Raised $155M across 3 rounds · 3 rounds over 3 yrs (1.0/yr) AI: Classified as an AI company rank vs industry peers · Fliar Intelligence Index 57/100 | $155M | 2 mo ago | — | Shantanu Phatakwala Co-Founder & Chief Commercial Officer | — | 7 job openings · 1 partnership · 1 award |
| 17 | Hippocratic AI 🦄 Developer of safety-focused generative AI for healthcare 78Funding top 13%AI top 23%Moat top 26%Talent top 32% All 9 signals ▾Fundingtop 13% AItop 23% Moattop 26% Talenttop 32% Newstop 33% Growthtop 40% Techtop 42% Markettop 47% Globalbottom 37% Funding: Raised $137M across 6 rounds · 6 rounds over 3 yrs (2.0/yr) AI: Classified as an agentic-AI company · Product described with: generative ai rank vs industry peers · Fliar Intelligence Index 78/100 | $137M | 7 mo ago | 35 | Debajyoti Datta Co-Founder | — | — |
| 18 | Equip Provider of virtual therapy and consultation for eating disorders 64Growth top 17%Funding top 18%Tech top 28%Moat top 28% All 10 signals ▾Growthtop 17% Fundingtop 18% Techtop 28% Moattop 28% Talenttop 38% Producttop 40% Marketbottom 42% Globalbottom 32% Newsbottom 18% Customersbottom 3% Growth: Headcount 15 → 32 (+113%) across vintages · Web rank 5,000,000 → 1,000,000 YoY Funding: Raised $130M across 4 rounds · 4 rounds over 5 yrs (0.8/yr) rank vs industry peers · Fliar Intelligence Index 64/100 | $130M | 10 mo ago | 32 | Kristina Saffran Cofounder and CEO | — | — |
| 19 | BigHealth CBT therapy for insomnia patients 69Tech top 14%Funding top 23%Moat top 31%News top 36% All 11 signals ▾Techtop 14% Fundingtop 23% Moattop 31% Newstop 36% Markettop 37% Talenttop 38% Producttop 40% Growthtop 44% Fin. healthtop 44% Globalbottom 45% Customersbottom 1% Tech: 62 technologies across 7/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 Funding: Raised $129M across 5 rounds · 5 rounds over 12 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 69/100 | $129M | 4 mo ago | 251 251 → 156 (-38%) · sector median +23% | Colin Espie Co-Founder | — | 1 partnership |
| 20 | Join Midi 🦄 Provider of a virtual care platform focused on female midlife health 80Funding top 14%Growth top 15%News top 20%Tech top 26% All 10 signals ▾Fundingtop 14% Growthtop 15% Newstop 20% Techtop 26% Producttop 33% Markettop 39% Innovationtop 40% Moattop 47% Talentbottom 49% Globalbottom 32% Funding: Raised $104M across 6 rounds · 6 rounds over 4 yrs (1.5/yr) Growth: Web rank 500,000 → 50,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 80/100 | $104M | 4 mo ago | 52 | Joanna Strober Founder | — | — |
| 21 | Phil Technology-driven hub simplifying medication access and improving patient outcomes 72Funding top 20%Growth top 29%Moat top 31%Tech top 38% All 7 signals ▾Fundingtop 20% Growthtop 29% Moattop 31% Techtop 38% Talenttop 38% Markettop 45% Globalbottom 37% Funding: Raised $98.0M across 6 rounds · 6 rounds over 11 yrs (0.5/yr) Growth: Headcount 71 → 99 (+39%) across vintages · Web rank 1,000,000 → 500,000 YoY rank vs industry peers · Fliar Intelligence Index 72/100 | $98M | 11 mo ago | 99 | Puran Singh Co-Founder/VP | — | 1 partnership |
| 22 | Modern Animal Platform offering virtual veterinary care services 89Tech top 12%Growth top 14%Funding top 19%News top 28% All 10 signals ▾Techtop 12% Growthtop 14% Fundingtop 19% Newstop 28% Customerstop 29% Moattop 31% Markettop 37% Talenttop 38% Producttop 42% Globalbottom 37% Tech: 61 technologies across 7/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 Growth: Headcount 54 → 163 (+202%) across vintages · Web rank 10,000,000 → 100,000 YoY rank vs industry peers · Fliar Intelligence Index 89/100 | $89M | 9 mo ago | 163 163 → 372 (+128%) · sector median +23% | Steven Eidelman Founder & CEO | — | — |
| 23 | Medallion Cloud-based solution for licensing, credentialing, and other practice management for healthcare providers 64Funding top 18%Growth top 18%News top 18%Moat top 31% All 10 signals ▾Fundingtop 18% Growthtop 18% Newstop 18% Moattop 31% Techtop 37% Markettop 47% Talentbottom 49% Globalbottom 42% Innovationbottom 40% Patentsbottom 37% Funding: Raised $85.0M across 4 rounds · 4 rounds over 5 yrs (0.8/yr) Growth: Headcount 69 → 172 (+149%) across vintages · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 64/100 | $85M | 10 mo ago | 172 | Derek Lo Founder & CEO | 9 patents Z-axis twist-pin interconnects for stacked circuit board modules | — |
| 24 | Tebra 🦄 Cloud based platform offering practice management tool for providers 74Funding top 18%Tech top 21%News top 22%Growth top 25% All 11 signals ▾Fundingtop 18% Techtop 21% Newstop 22% Growthtop 25% Moattop 26% Markettop 28% Producttop 43% Talentbottom 49% Innovationbottom 46% Globalbottom 38% Customersbottom 16% Funding: Raised $72.0M across 2 rounds · 2 rounds over 4 yrs (0.5/yr) Tech: 54 technologies across 6/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 rank vs industry peers · Fliar Intelligence Index 74/100 | $72M | 6 mo ago | 1,000 | Dan Rodrigues Co-Founder & CEO | — | 2 launchs |
| 25 | Fathom Provider of autonomous medical coding platform and related coding services 55AI top 20%Funding top 26%Moat top 31%News top 36% All 12 signals ▾AItop 20% Fundingtop 26% Moattop 31% Newstop 36% Growthtop 38% Talenttop 38% Producttop 49% Techbottom 49% Marketbottom 45% Patentsbottom 42% Innovationbottom 34% Globalbottom 31% AI: Classified as an AI company Funding: Raised $61.0M across 1 rounds · 1 rounds over 5 yrs (0.2/yr) rank vs industry peers · Fliar Intelligence Index 55/100 | $61M | 1 mo ago | 79 | Andrew Lockhart Co-Founder & CEO | 9 patents On-demand additive manufacturing and automated pricing for custom 3D-printed parts and injection molds | — |
| 26 | NewLimit 🦄 Developer of epigenetic reprogramming medicines for aging-related diseases and healthspan extension 62Funding top 22%Talent top 28%Growth top 35%AI top 45% All 9 signals ▾Fundingtop 22% Talenttop 28% Growthtop 35% AItop 45% Techtop 46% Moattop 47% Marketbottom 36% Globalbottom 36% Newsbottom 18% Funding: Raised $60.0M across 3 rounds · 3 rounds over 3 yrs (1.0/yr) Talent: 3 named leaders on record · 3 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 62/100 | $60M | 7 mo ago | 8 | Jacob Kimmel Co-Founder | — | 4 job openings |
| 27 | Aureka Biotechnologies Biotech company digitizing therapeutic discovery to manage human health 55Funding top 20%AI top 35%Talent top 38%Market bottom 37% All 5 signals ▾Fundingtop 20% AItop 35% Talenttop 38% Marketbottom 37% Globalbottom 36% Funding: Raised $58.0M across 2 rounds · 2 rounds over 1 yrs (2.0/yr) AI: Product described with: ai-based, artificial intelligence rank vs industry peers · Fliar Intelligence Index 55/100 | $58M | 1 mo ago | — | Weian Zhao Co-Founder & CEO | — | — |
| 28 | Cartography Biosciences Provider of a platform to discover immunotherapeutics 24Funding top 23%Moat top 31%News top 39%Talent bottom 49% All 6 signals ▾Fundingtop 23% Moattop 31% Newstop 39% Talentbottom 49% Globalbottom 37% Marketbottom 27% Funding: Raised $57.0M across 2 rounds · 2 rounds over 4 yrs (0.5/yr) Moat: Editorial + unicorn rating 8/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 24/100 | $57M | 1 mo ago | 10 | Howard Chang Co-Founder | — | — |
| 29 | Turquoise Online platform for employee health benefits 45Funding top 19%Moat top 39%Tech bottom 49%Talent bottom 49% All 8 signals ▾Fundingtop 19% Moattop 39% Techbottom 49% Talentbottom 49% Growthbottom 48% Marketbottom 44% Newsbottom 37% Globalbottom 37% Funding: Raised $55.0M across 4 rounds · 4 rounds over 5 yrs (0.8/yr) Moat: Editorial + unicorn rating 7/10 · 10 curated direct competitors tracked rank vs industry peers · Fliar Intelligence Index 45/100 | $55M | 3 mo ago | 52 | Chris Severn Co-Founder & CEO | — | — |
| 30 | Enlitic AI-based radiology database management tool 55Product top 14%Funding top 23%AI top 28%Innovation top 32% All 12 signals ▾Producttop 14% Fundingtop 23% AItop 28% Innovationtop 32% Patentstop 32% Growthtop 43% Moattop 43% Techtop 46% Globalbottom 47% Fin. healthbottom 33% Marketbottom 31% Newsbottom 24% Product: 9 distinct product lines · Company stage: Public Funding: Raised $55.0M across 6 rounds · 6 rounds over 12 yrs (0.5/yr) rank vs industry peers · Fliar Intelligence Index 55/100 | $55M | 5 mo ago | 16 16 → 34 (+112%) · sector median +23% | — | 175 patents AI-driven medical imaging analysis, quality assurance, and automated report generation | 1 job opening · 1 launch · 1 partnership |
| 31 | BridGene Biosciences Developer of small-molecule drugs for the treatment of cancer 69Growth top 20%Patents top 23%Funding top 24%Innovation top 26% All 8 signals ▾Growthtop 20% Patentstop 23% Fundingtop 24% Innovationtop 26% Moattop 28% Talenttop 38% Globalbottom 40% Marketbottom 36% Growth: Headcount 15 → 25 (+67%) across vintages · Fresh capital in last 24 mo Patents: 44 patents matched (strict assignee match) · 35 filings since 2022 vs 9 in 2017-21 rank vs industry peers · Fliar Intelligence Index 69/100 | $50M | 8 mo ago | 25 25 → 31 (+24%) · sector median +23% | Irene Yuan Co-Founder & Executive Vice President | 44 patents Small-molecule kinase and YAP/TAZ-TEAD inhibitors for targeted cancer therapy | — |
| 32 | PreludeDx Provider of risk assessment test for early stage breast cancer 50Funding top 27%Moat top 31%Growth top 32%Product top 46% All 10 signals ▾Fundingtop 27% Moattop 31% Growthtop 32% Producttop 46% Innovationtop 47% Techtop 47% Talentbottom 49% Marketbottom 37% Globalbottom 37% Newsbottom 22% Funding: Raised $46.7M across 6 rounds · 6 rounds over 10 yrs (0.6/yr) Moat: Editorial + unicorn rating 8/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 50/100 | $47M | 7 mo ago | 33 | Dan Forche President and CEO | — | — |
| 33 | Digital Optics Corporation 🦄 Provides MEMS technology based camera lens and modules 62Funding top 31%Innovation top 33%Patents top 34%Growth top 35% All 9 signals ▾Fundingtop 31% Innovationtop 33% Patentstop 34% Growthtop 35% Moattop 36% Techtop 41% Producttop 42% Marketbottom 44% Globalbottom 40% Funding: Raised $45.0M across 5 rounds · 5 rounds over 26 yrs (0.2/yr) Innovation: 62 patents (top 17% of patent-holders) rank vs industry peers · Fliar Intelligence Index 62/100 | $45M | 4 mo ago | 23 | — | 62 patents Wafer-level optoelectronic packaging and integrated micro‑optical components for fiber coupling. | — |
| 34 | Profluent Bio Provider of an artificial intelligence-based protein design platform 50Funding top 23%AI top 30%Talent top 33%Moat top 39% All 8 signals ▾Fundingtop 23% AItop 30% Talenttop 33% Moattop 39% Growthtop 45% Techbottom 45% Globalbottom 37% Marketbottom 28% Funding: Raised $44.0M across 3 rounds · 3 rounds over 3 yrs (1.0/yr) AI: Classified as an AI company · Product described with: artificial intelligence rank vs industry peers · Fliar Intelligence Index 50/100 | $44M | 6 mo ago | 10 | Alexander Meeske Co-Founder | — | 1 partnership |
| 35 | Unnatural Products Developer of computational biology techniques platform to engineer peptides for undruggable targets 27Funding top 25%Moat top 48%Global bottom 38%Market bottom 35% All 5 signals ▾Fundingtop 25% Moattop 48% Globalbottom 38% Marketbottom 35% Newsbottom 33% Funding: Raised $38.0M across 3 rounds · 3 rounds over 7 yrs (0.4/yr) Moat: Editorial + unicorn rating 5/10 · 9 curated direct competitors tracked rank vs industry peers · Fliar Intelligence Index 27/100 | $38M | 3 mo ago | 22 | — | — | — |
| 36 | Signos Provider of a wearable device for blood glucose pattern monitoring 42Tech top 20%Funding top 25%Moat top 39%Customers top 44% All 10 signals ▾Techtop 20% Fundingtop 25% Moattop 39% Customerstop 44% Producttop 46% Talentbottom 49% Marketbottom 40% Globalbottom 36% Growthbottom 31% Newsbottom 22% Tech: 52 technologies across 6/8 capability areas · Cloud: Amazon Cloudfront, Amazon Web Services Funding: Raised $37.0M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 42/100 | $37M | 0 mo ago | 30 | Sharam Fouladgar-Mercer Co-Founder & CEO | — | — |
| 37 | House Rx Provider of a technology-based medication solution for patients and caregivers 48Funding top 24%Growth top 35%Moat top 37%Talent bottom 49% All 10 signals ▾Fundingtop 24% Growthtop 35% Moattop 37% Talentbottom 49% Marketbottom 46% Techbottom 46% Patentsbottom 44% Newsbottom 43% Innovationbottom 40% Globalbottom 37% Funding: Raised $34.0M across 4 rounds · 4 rounds over 4 yrs (1.0/yr) Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 48/100 | $34M | 7 mo ago | 94 | Ogi Kavazovic Co-Founder & CEO | 16 patents House Rx patents cover kitchen cookware, specifically pans and griddles. | — |
| 38 | Quartzy Provider of web-based platform for labs management 67Funding top 24%Growth top 26%Tech top 37%Innovation top 38% All 10 signals ▾Fundingtop 24% Growthtop 26% Techtop 37% Innovationtop 38% Moattop 39% Producttop 42% Marketbottom 49% Talentbottom 49% Newsbottom 47% Globalbottom 37% Funding: Raised $33.9M across 6 rounds · 6 rounds over 14 yrs (0.4/yr) Growth: Headcount 54 → 97 (+80%) across vintages · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 67/100 | $34M | 2 mo ago | 97 97 → 92 (-5%) · sector median +23% | Adam Regelman Co-Founder & CPO | — | 1 job opening · 1 launch · 2 partnerships |
| 39 | 9amHealth Provider of whole-body approach to healthcare delivering multiple services 55Funding top 26%Talent top 28%Growth top 35%Tech top 38% All 10 signals ▾Fundingtop 26% Talenttop 28% Growthtop 35% Techtop 38% Producttop 46% Moattop 48% Marketbottom 39% Globalbottom 37% Newsbottom 22% Customersbottom 14% Funding: Raised $29.8M across 2 rounds · 2 rounds over 4 yrs (0.5/yr) Talent: 4 named leaders on record · 4 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 55/100 | $30M | 3 mo ago | 35 | Paul Geevarghese Co-Founder & COO | — | — |
| 40 | Triomics Provider of clinical research and clinical trial tracking software 60AI top 20%Funding top 26%Talent top 38%Moat top 39% All 8 signals ▾AItop 20% Fundingtop 26% Talenttop 38% Moattop 39% Techtop 40% Growthtop 47% Globalbottom 43% Marketbottom 35% AI: Classified as an AI company Funding: Raised $28.9M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 60/100 | $29M | 0 mo ago | 29 | Hrituraj Singh Co-Founder & CTO | — | — |
| 41 | Luminai Artificial intelligence based platform offering internal workflow automation solutions 62Funding top 27%Growth top 28%News top 29%Tech top 35% All 9 signals ▾Fundingtop 27% Growthtop 28% Newstop 29% Techtop 35% Talenttop 38% Moattop 39% AItop 45% Globalbottom 37% Marketbottom 29% Funding: Raised $24.1M across 3 rounds · 3 rounds over 6 yrs (0.5/yr) Growth: Web rank 10,000,000 → 5,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 62/100 | $24M | 2 mo ago | 9 | Dmitry Dolgopolov Co-Founder | — | — |
| 42 | Condor Software-based financial management platform for clinical industries 29Funding top 27%News top 29%Talent top 38%Tech top 45% All 9 signals ▾Fundingtop 27% Newstop 29% Talenttop 38% Techtop 45% Moattop 48% Innovationbottom 46% Productbottom 45% Globalbottom 32% Marketbottom 21% Funding: Raised $24.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) News: 3 BI events in 12 mo (of 5 tracked, 3 types) · +200% YoY rank vs industry peers · Fliar Intelligence Index 29/100 | $24M | 3 mo ago | 8 | John Sammataro Co-Founder | — | — |
| 43 | Cognixion Developer of an AI and AR-based application for speech impaired individuals 69AI top 15%Innovation top 17%Patents top 21%Moat top 32% All 11 signals ▾AItop 15% Innovationtop 17% Patentstop 21% Moattop 32% Fundingtop 35% Growthtop 35% Techtop 49% Talentbottom 49% Globalbottom 40% Marketbottom 33% Newsbottom 22% AI: Holds AI/ML patents (G06N-family CPC) Innovation: 55 patents (top 19% of patent-holders) · 43 filings since 2022 vs 12 in 2017-21 rank vs industry peers · Fliar Intelligence Index 69/100 | $23M | 4 mo ago | 34 | Andreas Forsland Founder | 55 patents Neural interface hardware and biosignal-driven BCI software for AR communication | 1 award |
| 44 | Sinopia Biosciences Data-driven drug discovery using multi-omics, AI, and disease models 13Funding top 28%AI top 45%Global bottom 29%Tech bottom 26% All 5 signals ▾Fundingtop 28% AItop 45% Globalbottom 29% Techbottom 26% Marketbottom 16% Funding: Raised $19.4M across 13 rounds · 13 rounds over 5 yrs (2.6/yr) AI: Product described with: machine learning rank vs industry peers · Fliar Intelligence Index 13/100 | $19M | 2 mo ago | 4 | — | — | — |
| 45 | General Proximity Developer of next generation of induced-proximity medicines 22Funding top 31%Talent bottom 49%Global bottom 48%Tech bottom 42% All 5 signals ▾Fundingtop 31% Talentbottom 49% Globalbottom 48% Techbottom 42% Marketbottom 24% Funding: Raised $16.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 22/100 | $16M | 1 mo ago | 11 | Armand Cognetta III Founder & CEO | — | — |
| 46 | Solace Health 🦄 Provider of patient centered healthcare platform 64Funding top 24%Tech top 26%Growth top 28%Moat top 31% All 7 signals ▾Fundingtop 24% Techtop 26% Growthtop 28% Moattop 31% Talenttop 38% Marketbottom 38% Globalbottom 37% Funding: Raised $14.0M across 3 rounds · 3 rounds over 2 yrs (1.5/yr) Tech: 49 technologies across 5/8 capability areas · Cloud: Cloudflare, Heroku rank vs industry peers · Fliar Intelligence Index 64/100 | $14M | 4 mo ago | 1 | Sara Sargent Co-Founder | — | 5 job openings · 1 partnership |
| 47 | Boost Developer of software for managing behavioral health practice administrative workflows 45Funding top 36%Patents bottom 48%Tech bottom 46%Talent bottom 45% All 6 signals ▾Fundingtop 36% Patentsbottom 48% Techbottom 46% Talentbottom 45% Innovationbottom 44% Globalbottom 43% Funding: Raised $10.9M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Patents: 12 patents matched (strict assignee match) · Latest publication 2015 rank vs industry peers · Fliar Intelligence Index 45/100 | $11M | 2 mo ago | — | Lani Fritts CEO | 12 patents Patents concentrated in health & consumer products | 1 award |
| 48 | Aumet Provider of B2B transaction management solutions for healthcare companies 72Customers top 21%Tech top 22%Funding top 35%Growth top 37% All 10 signals ▾Customerstop 21% Techtop 22% Fundingtop 35% Growthtop 37% Talenttop 38% Markettop 44% Producttop 47% Moattop 48% Newsbottom 43% Globalbottom 38% Customers: Play-Store rating 4.80★ across 1,403 ratings (2 apps) · Review volume +27% in 6 mo Tech: 71 technologies across 6/8 capability areas · Cloud: Cloudflare rank vs industry peers · Fliar Intelligence Index 72/100 | $8M | 1 mo ago | 133 | Yahya Aqel Co-Founder & CEO | — | 1 launch |
| 49 | Blank Bio Developer of RNA foundation models for precision medicine research applications 60Talent top 28%Funding top 35%Global bottom 48% All 3 signals ▾Talenttop 28% Fundingtop 35% Globalbottom 48% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Funding: Raised $7.2M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 60/100 | $7M | 1 mo ago | — | Jonathan Hsu Co-Founder & CEO | — | — |
| 50 | Century Health AI-powered health tech company accelerating access to breakthrough treatments 45Funding top 35%Talent top 38%AI top 45%Market bottom 37% All 5 signals ▾Fundingtop 35% Talenttop 38% AItop 45% Marketbottom 37% Globalbottom 29% Funding: Raised $7.0M across 2 rounds · 2 rounds over 2 yrs (1.0/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 45/100 | $7M | 1 mo ago | — | Vish Srivastava Co-Founder & CEO | — | — |
Top 12 HealthTech companies in California
#1
Series D · Stanford, California · founded 2013 · 50 employees$157.1Mraised▾
Developer of a wearable non-invasive neuromodulation device. The company has developed a neuromodulation device that aims to provide relief of hand tremors in adults with essential tremors. It combines a watch-like device with an implantable sensor that externally stimulates peripheral nerves to reduce the same. The company has also developed a portable medical device with sensors to monitor the physical movement of a patient wearing or carrying the device.
- Apr 2026Conventional Debt$50M
- Oct 2025Series D$50M
- Dec 2024Series D$50M
- May 2022Series D—
#2
Series C · San Diego, California · founded 2019 · 50 employees$206.2Mraised▾
Provider of AI-driven drug discovery platform for the treatment of cancer. It offers an AI driven discovery platform and has discovered two candidates known as IAM-H1, a highly selective and brain penetrant inhibitor of HER2 and its oncogenic mutants, and IAM-C1 a potential first-in-class selective dual CDK2/4 inhibitor to address unmet needs in terms of therapeutic window and treatment resistance in cell cycle driven cancers.
- Apr 2026Series C$27.8M
- Nov 2025Series C$100M
- Apr 2024Series B$50M
- Oct 2023Series B$103.2M
#3
Series B · San Carlos, California · founded 2023$155Mraised▾
Provider of an enterprise AI platform for healthcare systems. The platform unifies workflows, use cases, and models under a governed operating layer. It offers data integration, deployable solutions, and workflow builder tools. The platform provides governance, workforce education, and continuous outcome tracking.
- Mar 2026Series B$125M
- Jan 2025Series A$25M
- 2023Seed$5M
#4
Series C · San Francisco, California · founded 2010 · 251 employees$129.3Mraised▾
CBT therapy for insomnia patients. Its flagship product Sleepio is a digital sleep improvement program, clinically proven to help users overcome poor sleep. Its virtual sleep expert "The Prof" teaches users proven Cognitive Behavioral Therapy (CBT) techniques, personalized to their problems and monitors their progress. Sleepio has been validated in the world’s first placebo-controlled RCT for a digital sleep intervention.
- Feb 2026Series C$23.7M
- Jan 2022Series C$75M
- Jun 2020Series B$39M
- Jul 2016Series B$12M
#5
Series C · San Jose, California · founded 2017 · 165 employees$166.1Mraised▾
BrightInsight provides digital health solutions for clinical trials. Their platform enables improving patient engagement and adherence, continuous remote patient monitoring, and dose management algorithms (cloud-based algorithm). It analyzes data from connected medical devices, combination products, apps, and software. The company's Quality Management System is ISO 13485: 2016 certified.
- Jan 2026Series C$13M
- Mar 2021Series C$101M
- Jun 2020Series B$40.1M
- Sep 2019Series A$25M
#6
Series B · Foster City, California · founded 2020 · 10 employees$57Mraised▾
Provider of a platform to discover immunotherapeutics. It provides a platform that combines computational and experimental techniques to profile antigens of cancerous cells and identify targets for immuno-oncology treatments.
- May 2026Series B—
- Oct 2025Series B$67M
- Jul 2022Series A$57M
#7
Series B · San Francisco, California · founded 2020 · 30 employees$37Mraised▾
Provider of a wearable device for blood glucose pattern monitoring. The company has developed an app-based platform that recommends meals and exercises for users based on the glucose pattern detected through the connected device. The app provides real-time glucose monitoring and glucose spike levels for different foods. Based on this, personalized fitness and nutrition plan can be developed.
- Oct 2023Series B$20M
- Nov 2021Series A$13M
- Jan 2021Seed$4M
#8
Series B · San Francisco, California · founded 2017 · 79 employees$61Mraised▾
Provider of autonomous medical coding platform and related coding services. The company offers production coding, backlog processing, and real-time audit functionalities. The platform automates medical coding, aiming to reduce costs and improve accuracy. It provides coding capacity and helps to review coding work.
- May 2026Series B—
- Nov 2022Series B$46.3M
- Apr 2022Seed—
- Feb 2021Seed—
#9
Series D · Los Altos Hills, California · founded 2021 · 52 employees$104Mraised▾
Provider of a virtual care platform focused on female midlife health
- Feb 2026Series D$100M
- Oct 2025Series C$50M
- Sep 2024Series B$5M
- Apr 2024Series B$60M
#10
Series A · Laguna Hills, California · founded 2023$58Mraised▾
Biotech company digitizing therapeutic discovery to manage human health. It utilize microfluidics in use of drug discovery and offer solutions for pharmaceutical and biotech research using artificial intelligence. The platform offers immunotherapeutic discovery, developing new therapeutics, drug discovery, single-cell-based functional screening and AI-based drug design and development for generating multi metric data from analyzing multiple candidates.
- Apr 2026Series A$35M
- Nov 2025Series A$23M
#11
Series B · San Francisco, California · founded 2023$230Mraised▾
Developer of artificial intelligence models for de novo molecular design. The company focuses on engineering better molecules through advanced computational methods. It introduces new model series designed to achieve high hit rates in antibody design. The company provides access to its technology for molecular research and development.
- Dec 2025Series B$130M
- Aug 2025Series A$70M
- Sep 2024Seed$30M
#12
Series B · San Francisco, California · founded 2020 · 29 employees$28.9Mraised▾
Provider of clinical research and clinical trial tracking software. The features of the software include an end-to-end platform for running clinical trials, unifying the workflows of clinical care and clinical research, and eliminating the operational inefficiencies in data collection, patient recruitment, and other laborious tasks involved in clinical research.
- May 2024Series B$15M
- Dec 2022Series A$13.8M
- 2021Seed$125K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of HealthTech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health in California is moving
A read on the academic research around Digital Health in California — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 626 papers.
UCSF, UCLA, and UC San Diego lead California's digital-health research—dominated by mobile health, telehealth, and digital mental health—with a cautiously contested tone reflecting more concerns than breakthroughs.
- University of California, San Francisco154
- University of California, Los Angeles80
- University of California San Diego75
- University of California, Irvine73
- University of Southern California62
- Wearable computer2→14
- Health care1→13
- Health informatics4→9
- Telemedicine1→5
- Remote patient monitoring4→7
- Health care4→58
- Health informatics10→38
- mHealth2→25
- Psychological intervention1→23
- Public health3→20
- Health care4→47
- Health informatics11→53
- Public health3→34
- Health administration9→32
- Psychological intervention4→25