Radar · Life Sciences in California
Best Life Sciences Companies in California, United States
The 5090 best Life Sciences companies in California, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: GRAIL.
By Riya SenguptaFinancials
5090companies tracked
$153.4Bdisclosed funding
20unicorns
2752have raised
FLIAR INTELLIGENCE · LIFE SCIENCES × CALIFORNIA
Our analysis of 164 Life Sciences companies
$34.7b in tracked funding; 83% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
164companies analysed
83%cloud-native stacks
2025funding peak (by rounds)
7unicorns
2016median founding year
1.3Mcombined LinkedIn audience
60%of audience held by top 3
8companies hiring publicly (12 mo)
Ranked: Best Life Sciences companies in California
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|
| 1 | GRAIL Developer of a screening platform for circulating tumor DNA to detect cancer 78Patents top 13%Tech top 16%News top 17%Funding top 20% All 12 signals ▾Patentstop 13% Techtop 16% Newstop 17% Fundingtop 20% Innovationtop 25% Growthtop 36% Markettop 37% Moattop 38% Partnerstop 40% Globaltop 49% Fin. healthbottom 49% Talentbottom 49% Patents: 899 patents matched (strict assignee match) · 523 filings since 2022 vs 371 in 2017-21 Tech: 51 technologies across 6/8 capability areas · Cloud: Amazon Alb, Amazon Cloudfront rank vs industry peers · Fliar Intelligence Index 78/100 | $2.0B | 7 mo ago | 491 491 → 1,111 (+126%) · sector median +32% | Bob Ragusa Chief Executive Officer | WordPressApple iCloud MailGoogle Workspace+24 | 899 patents Liquid biopsy cancer detection via cfDNA methylation and fragment analysis | — |
| 2 | Rakuten Medical Developer of a photoimmunotherapy platform for treating cancer 69Funding top 12%Moat top 24%Patents top 25%Innovation top 34% All 10 signals ▾Fundingtop 12% Moattop 24% Patentstop 25% Innovationtop 34% Growthtop 35% Newstop 39% Markettop 45% Techtop 46% Talentbottom 49% Globalbottom 42% Funding: Raised $874M across 12 rounds · 12 rounds over 11 yrs (1.1/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 150 patents rank vs industry peers · Fliar Intelligence Index 69/100 | $874M | 11 mo ago | 110 110 → 129 (+17%) · sector median +32% | Hiroshi Mikitani Chairman & CEO | WordPressApple iCloud MailMySQL+27 | 150 patents Photodynamic therapy delivery devices and catheter-based drug administration technologies | — |
| 3 | Summit Developer of therapeutics for oncology and rare diseases 22Partners top 31%Funding top 33%Product top 35%News top 37% All 13 signals ▾Partnerstop 31% Fundingtop 33% Producttop 35% Newstop 37% Techtop 45% Growthbottom 43% Moatbottom 43% Marketbottom 42% Talentbottom 41% Globalbottom 37% Patentsbottom 30% Innovationbottom 26% Fin. healthbottom 22% Partners: 3 contract events in 12 mo · Named contractor/client in 3 deals Funding: Raised $713M across 4 rounds · 4 rounds over 6 yrs (0.7/yr) rank vs industry peers · Fliar Intelligence Index 22/100 | $713M | 7 mo ago | 99 | Maky Zanganeh CEO | WordPress Block EditorWordPressMySQL+18 | 13 patents Digital media submission, processing, and distribution platforms for online content management. | — |
| 4 | Neuralink 🦄 Provider of implantable brain-computer interfaces 78Funding top 15%Patents top 25%Moat top 25%Innovation top 27% All 10 signals ▾Fundingtop 15% Patentstop 25% Moattop 25% Innovationtop 27% Talenttop 28% Markettop 33% Growthtop 42% Techtop 44% Globalbottom 39% Newsbottom 24% Funding: Raised $680M across 6 rounds · 6 rounds over 9 yrs (0.7/yr) Patents: 97 patents matched (strict assignee match) · 62 filings since 2022 vs 35 in 2017-21 rank vs industry peers · Fliar Intelligence Index 78/100 | $680M | 1 mo ago | 197 | Dongjin Seo Co-Founder | Apple iCloud MailGoogle WorkspaceGSAP+12 | 97 patents High‑density, biocompatible neural interface hardware and real‑time spike processing | 1 launch |
| 5 | Kriya Therapeutics Developer of therapeutic solutions for the treatment of diabetes 53Funding top 16%News top 24%Moat top 31%Growth top 43% All 8 signals ▾Fundingtop 16% Newstop 24% Moattop 31% Growthtop 43% Markettop 44% Talenttop 50% Globalbottom 37% Techbottom 32% Funding: Raised $618M across 4 rounds · 4 rounds over 7 yrs (0.6/yr) News: 5 BI events in 12 mo (of 16 tracked, 3 types) · 3 high-value events (IPO/M&A/funding/contracts) in 12 mo rank vs industry peers · Fliar Intelligence Index 53/100 | $618M | 10 mo ago | 159 | Shankar Ramaswamy Co-Founder & CEO | WordPress Site EditorWordPressMySQL+12 | — | — |
| 6 | Guardant Health Developer of digital sequencing technology for cancer detection 90Patents top 14%Funding top 15%Innovation top 17%Moat top 19% All 13 signals ▾Patentstop 14% Fundingtop 15% Innovationtop 17% Moattop 19% Markettop 23% Techtop 23% Newstop 29% Growthtop 30% Producttop 35% Fin. healthtop 36% Partnerstop 41% Globaltop 45% Talenttop 46% Patents: 996 patents matched (strict assignee match) · 615 filings since 2022 vs 346 in 2017-21 Funding: Raised $557M across 7 rounds · 7 rounds over 12 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 90/100 | $557M | 7 mo ago | 1,351 | Amirali Talasaz Co-founder and Co-Chief Executive Officer | WordPressBugHerdApple iCloud Mail+25 | 996 patents Liquid biopsy cfDNA sequencing and analysis for cancer detection and monitoring | 1 launch · 1 partnership |
| 7 | Imperative Care Provider of access catheters for cardiovascular diagnosis and treatment 82Funding top 14%Patents top 15%Innovation top 18%Moat top 26% All 10 signals ▾Fundingtop 14% Patentstop 15% Innovationtop 18% Moattop 26% Growthtop 27% Techtop 36% Talenttop 38% Markettop 48% Newsbottom 48% Globalbottom 42% Funding: Raised $496M across 4 rounds · 4 rounds over 7 yrs (0.6/yr) Patents: 261 patents matched (strict assignee match) · 225 filings since 2022 vs 36 in 2017-21 rank vs industry peers · Fliar Intelligence Index 82/100 | $496M | 3 mo ago | 90 | Dr Hopkins Co-founder | WordPressApple iCloud MailMicrosoft 365+27 | 261 patents Robotic-assisted neurovascular catheter systems for precise multi‑catheter interventions | — |
| 8 | Mirador Developer of therapeutics for immune-mediated inflammatory and fibrotic diseases 50Funding top 15%Growth top 35%Moat top 42%Tech top 44% All 9 signals ▾Fundingtop 15% Growthtop 35% Moattop 42% Techtop 44% Producttop 49% Talentbottom 49% Newsbottom 38% Globalbottom 36% Marketbottom 32% Funding: Raised $480M across 3 rounds · 3 rounds over 3 yrs (1.0/yr) Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 50/100 | $480M | 5 mo ago | — | Mark McKenna Founder & CEO | WordPressApple iCloud MailMicrosoft 365+21 | — | — |
| 9 | Quince Therapeutics Developer of therapeutics for orthopedic diseases 53Funding top 13%Growth top 37%Tech top 44%Moat top 48% All 8 signals ▾Fundingtop 13% Growthtop 37% Techtop 44% Moattop 48% Talentbottom 49% Marketbottom 37% Newsbottom 37% Globalbottom 37% Funding: Raised $420M across 7 rounds · 7 rounds over 12 yrs (0.6/yr) Growth: Web rank 50,000,000 → 5,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 53/100 | $420M | 1 mo ago | 21 | Dirk Thye CEO | DrupalPHPZURB Foundation+20 | — | — |
| 10 | Science 🦄 Provider of online science magazine 72Funding top 13%Patents top 20%Moat top 24%Innovation top 33% All 9 signals ▾Fundingtop 13% Patentstop 20% Moattop 24% Innovationtop 33% Growthtop 35% Markettop 38% Globaltop 42% Talentbottom 49% Techbottom 46% Funding: Raised $360M across 3 rounds · 3 rounds over 2 yrs (1.5/yr) Patents: 245 patents matched (strict assignee match) · 102 filings since 2022 vs 115 in 2017-21 rank vs industry peers · Fliar Intelligence Index 72/100 | $360M | 3 mo ago | 76 | Max Hodak Founder & CEO | Apple iCloud MailGoogle WorkspaceRuby+12 | 245 patents Specialty surfactants and polyether polymer derivatives for cosmetics and advanced chemical synthesis | 3 job openings · 1 award |
| 11 | Cellares Manufacturer of a medical device for cell-based therapy 82Funding top 15%News top 19%Innovation top 23%Growth top 25% All 11 signals ▾Fundingtop 15% Newstop 19% Innovationtop 23% Growthtop 25% Patentstop 27% Moattop 28% Partnerstop 31% Talenttop 35% Markettop 41% Techtop 43% Globalbottom 39% Funding: Raised $355M across 4 rounds · 4 rounds over 7 yrs (0.6/yr) News: 9 BI events in 12 mo (of 25 tracked, 4 types) · +200% YoY rank vs industry peers · Fliar Intelligence Index 82/100 | $355M | 4 mo ago | 154 | Fabian Gerlinghaus Co-Founder & CEO | WordPressApple iCloud MailGoogle Workspace+32 | 89 patents Patents concentrated in transport & manufacturing processes | 1 partnership · 1 expansion · 1 award |
| 12 | ReCode Therapeutics Developer of precision medicines for treating lung related diseases 67Funding top 17%Talent top 28%Moat top 31%Market top 42% All 7 signals ▾Fundingtop 17% Talenttop 28% Moattop 31% Markettop 42% Newstop 45% Techtop 48% Globalbottom 39% Funding: Raised $342M across 7 rounds · 7 rounds over 7 yrs (1.0/yr) Talent: 3 named leaders on record · 3 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 67/100 | $342M | 8 mo ago | 105 | Daniel Siegwart Co-Founder | WordPressApple iCloud MailMicrosoft 365+28 | — | — |
| 13 | Orca Bio 🦄 Developer of Allogeneic cell therapy for cancer, autoimmune diseases and genetic blood disorders 74Funding top 18%Growth top 26%Moat top 26%Talent top 38% All 8 signals ▾Fundingtop 18% Growthtop 26% Moattop 26% Talenttop 38% Techtop 40% Markettop 42% Globalbottom 37% Newsbottom 18% Funding: Raised $300M across 2 rounds · 2 rounds over 7 yrs (0.3/yr) Growth: Headcount 39 → 66 (+69%) across vintages · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 74/100 | $300M | 5 mo ago | 66 | Jeroen Bekaert Co-Founder & COO | WordPressApple iCloud MailGoogle Workspace+29 | — | 1 expansion |
| 14 | Evommune Developer of therapeutic options for chronic inflammatory disorders 60Growth top 16%Funding top 18%News top 25%Tech top 47% All 10 signals ▾Growthtop 16% Fundingtop 18% Newstop 25% Techtop 47% Fin. healthtop 47% Moattop 47% Patentsbottom 47% Marketbottom 46% Innovationbottom 42% Globalbottom 39% Growth: Revenue +86% YoY · Fresh capital in last 24 mo Funding: Raised $268M across 6 rounds · 6 rounds over 6 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 60/100 | $268M | 4 mo ago | 33 | — | WordPressMySQLPHP+20 | 3 patents Small-molecule PKCθ inhibitors for immune‑modulating therapeutics | 2 launchs · 1 partnership |
| 15 | BlossomHill Therapeutics Provider of the drug for the treatment of oncology and autoimmune disorders 55Funding top 20%Patents top 21%Innovation top 23%Moat top 26% All 7 signals ▾Fundingtop 20% Patentstop 21% Innovationtop 23% Moattop 26% Newsbottom 42% Globalbottom 42% Marketbottom 34% Funding: Raised $260M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) Patents: 133 patents matched (strict assignee match) · 133 filings since 2022 vs 0 in 2017-21 rank vs industry peers · Fliar Intelligence Index 55/100 | $260M | 6 mo ago | 14 | — | — | 133 patents Patents concentrated in chemistry & materials | 3 job openings |
| 16 | Terremoto Developer of small-molecule therapeutics for cancer treatment 60Funding top 15%Talent top 28%Moat top 31%Growth top 35% All 7 signals ▾Fundingtop 15% Talenttop 28% Moattop 31% Growthtop 35% Techtop 49% Marketbottom 41% Globalbottom 36% Funding: Raised $250M across 3 rounds · 3 rounds over 4 yrs (0.8/yr) Talent: 3 named leaders on record · 3 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 60/100 | $250M | 2 mo ago | 35 | Matt Jacobson Co-Founder | WordPressBugHerdZendesk+24 | — | — |
| 17 | Alamar Biosciences Provider of solutions for ultra-high sensitivity protein analysis across a range of multiplex levels 67News top 18%Funding top 19%Growth top 30%Moat top 31% All 9 signals ▾Newstop 18% Fundingtop 19% Growthtop 30% Moattop 31% Talenttop 35% Techtop 37% Markettop 44% Fin. healthbottom 46% Globalbottom 36% News: 15 BI events in 12 mo (of 30 tracked, 5 types) · +67% YoY Funding: Raised $250M across 4 rounds · 4 rounds over 5 yrs (0.8/yr) rank vs industry peers · Fliar Intelligence Index 67/100 | $250M | 5 mo ago | 83 | Steve Chen Co-Founder | WordPressApple iCloud MailMicrosoft 365+37 | — | 1 internship · 1 launch · 1 expansion |
| 18 | Merge Labs Developer of brain-computer interfaces to maximize human ability, agency, experience 48Talent top 28%Funding top 31%AI top 45%Patents top 49% All 8 signals ▾Talenttop 28% Fundingtop 31% AItop 45% Patentstop 49% Innovationbottom 49% Techbottom 45% Globalbottom 42% Marketbottom 31% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Funding: Raised $250M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 48/100 | $250M | 5 mo ago | — | Sumner Norman Co-Founder | Apple iCloud MailGoogle WorkspaceNode.js+9 | 40 patents Real-time multi-user AR collaboration and interactive media streaming platforms | — |
| 19 | Rani Therapeutics Developer of technology for the oral delivery of large drug molecules 72Growth top 22%Funding top 23%Patents top 24%Talent top 27% All 11 signals ▾Growthtop 22% Fundingtop 23% Patentstop 24% Talenttop 27% Innovationtop 28% Newstop 30% Moattop 35% Techtop 45% Marketbottom 49% Fin. healthbottom 44% Globalbottom 42% Growth: Revenue +59% YoY · Fresh capital in last 24 mo Funding: Raised $234M across 6 rounds · 6 rounds over 13 yrs (0.5/yr) rank vs industry peers · Fliar Intelligence Index 72/100 | $234M | 7 mo ago | 163 | Mir Imran Founder | DrupalPHPZURB Foundation+25 | 456 patents Oral ingestible devices for delivering biologic therapeutics to the gastrointestinal tract | 1 launch |
| 20 | Chai Discovery 🦄 Developer of artificial intelligence models for de novo molecular design 72Funding top 14%Talent top 28%AI top 30%Moat top 32% All 7 signals ▾Fundingtop 14% Talenttop 28% AItop 30% Moattop 32% Markettop 48% Globalbottom 48% Techbottom 42% Funding: Raised $230M across 3 rounds · 3 rounds over 2 yrs (1.5/yr) Talent: 4 named leaders on record · 4 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 72/100 | $230M | 6 mo ago | — | Joshua Meier Co-Founder | Framer SitesReactPriority Hints+7 | — | 1 partnership |
| 21 | Aspen Neuroscience Provider of genomic-based personalised pluripotent stem cell therapy 64Funding top 17%Patents top 23%Moat top 28%Innovation top 33% All 10 signals ▾Fundingtop 17% Patentstop 23% Moattop 28% Innovationtop 33% Growthtop 35% Newstop 45% Marketbottom 49% Talentbottom 49% Techbottom 46% Globalbottom 45% Funding: Raised $224M across 5 rounds · 5 rounds over 7 yrs (0.7/yr) Patents: 57 patents matched (strict assignee match) · 51 filings since 2022 vs 6 in 2017-21 rank vs industry peers · Fliar Intelligence Index 64/100 | $224M | 6 mo ago | 94 | Damien Mcdevitt President | WordPress Block EditorWordPressMySQL+19 | 57 patents Patents concentrated in computing, sensing & instrumentation | — |
| 22 | NovaBay Pharmaceuticals Developer of eye care and wound care products 32Funding top 21%Product top 35%News top 46%Talent bottom 49% All 10 signals ▾Fundingtop 21% Producttop 35% Newstop 46% Talentbottom 49% Moatbottom 44% Marketbottom 43% Techbottom 41% Growthbottom 40% Globalbottom 38% Fin. healthbottom 37% Funding: Raised $220M across 13 rounds · 13 rounds over 11 yrs (1.2/yr) Product: 0 product launch events in 12 mo · Company stage: Public rank vs industry peers · Fliar Intelligence Index 32/100 | $220M | 5 mo ago | 33 33 → 38 (+15%) · sector median +32% | Justin Hall CEO | WordPressApple iCloud MailMicrosoft 365+20 | — | — |
| 23 | Iambic Therapeutics Provider of AI-driven drug discovery platform for the treatment of cancer 60Funding top 15%AI top 26%Moat top 31%Talent top 38% All 9 signals ▾Fundingtop 15% AItop 26% Moattop 31% Talenttop 38% Growthtop 45% Marketbottom 43% Newsbottom 43% Techbottom 40% Globalbottom 39% Funding: Raised $206M across 5 rounds · 5 rounds over 5 yrs (1.0/yr) AI: Classified as an AI company · Product described with: ai driven, ai-driven rank vs industry peers · Fliar Intelligence Index 60/100 | $206M | 2 mo ago | 50 | Fred Manby Co-Founder & CTO | WebflowApple iCloud MailMicrosoft 365+13 | — | — |
| 24 | Candid Therapeutics Developer of therapeutics for autoimmune diseases 40Funding top 17%Growth top 38%News top 48%Moat top 48% All 8 signals ▾Fundingtop 17% Growthtop 38% Newstop 48% Moattop 48% Talentbottom 49% Techbottom 38% Globalbottom 38% Marketbottom 32% Funding: Raised $206M across 2 rounds · 2 rounds over 2 yrs (1.0/yr) Growth: 1 acquisition/expansion move in 24 mo · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 40/100 | $206M | 3 mo ago | — | Ken Song CEO | WordPressMySQLPHP+15 | — | — |
| 25 | Bioventrix Ventricle reshaping device 40Funding top 16%Moat top 19%Patents top 36%Talent top 38% All 9 signals ▾Fundingtop 16% Moattop 19% Patentstop 36% Talenttop 38% Innovationtop 43% Globalbottom 45% Techbottom 36% Marketbottom 30% Newsbottom 27% Funding: Raised $181M across 25 rounds · 25 rounds over 22 yrs (1.1/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 185 patents rank vs industry peers · Fliar Intelligence Index 40/100 | $181M | 2 mo ago | 20 20 → 23 (+15%) · sector median +32% | Lon Annest Co-Founder | WordPressMySQLPHP+17 | 185 patents Percutaneous cardiac implant and monitoring systems for heart failure treatment | — |
| 26 | BrightInsight Provider of digital health solutions for clinical trials 57Funding top 18%Moat top 31%Growth top 35%Market top 50% All 8 signals ▾Fundingtop 18% Moattop 31% Growthtop 35% Markettop 50% Techbottom 49% Talentbottom 49% Newsbottom 43% Globalbottom 37% Funding: Raised $166M across 4 rounds · 4 rounds over 7 yrs (0.6/yr) Moat: Editorial + unicorn rating 8/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 57/100 | $166M | 4 mo ago | 165 165 → 145 (-12%) · sector median +32% | Frederik Smits Co-founder & Managing Director | lit-htmllit-elementcore-js+20 | — | — |
| 27 | Senti Bio Developer of cell and gene therapies for patients living with incurable diseases 45Product top 14%Funding top 21%Talent top 22%Tech top 32% All 11 signals ▾Producttop 14% Fundingtop 21% Talenttop 22% Techtop 32% Innovationtop 34% Newsbottom 43% Moatbottom 43% Growthbottom 39% Globalbottom 39% Marketbottom 32% Fin. healthbottom 20% Product: 4 distinct product lines · Company stage: Public Funding: Raised $158M across 8 rounds · 8 rounds over 8 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 45/100 | $158M | 1 mo ago | 122 | Jim Collins Co-Founder | DrupalPHPSalesforce+24 | — | — |
| 28 | Cala Health Developer of a wearable non-invasive neuromodulation device 60Funding top 17%Product top 21%Innovation top 22%Patents top 26% All 11 signals ▾Fundingtop 17% Producttop 21% Innovationtop 22% Patentstop 26% Moattop 26% Talenttop 38% Techtop 46% Growthbottom 44% Marketbottom 43% Globalbottom 42% Newsbottom 21% Funding: Raised $157M across 7 rounds · 7 rounds over 13 yrs (0.5/yr) Product: 6 distinct product lines · Company stage: Series D rank vs industry peers · Fliar Intelligence Index 60/100 | $157M | 1 mo ago | 50 50 → 122 (+144%) · sector median +32% | Kate Rosenbluth Founder and Co-President | WordPressApple iCloud MailGoogle Workspace+31 | 243 patents Wearable peripheral nerve stimulation devices for tremor, movement and musculoskeletal disorder therapy | 1 award |
| 29 | Angitia Developer of drugs for muscle, bone, and joint diseases 29Funding top 16%Talent top 38%Moat top 47%Market bottom 40% All 7 signals ▾Fundingtop 16% Talenttop 38% Moattop 47% Marketbottom 40% Globalbottom 39% Innovationbottom 23% Patentsbottom 20% Funding: Raised $156M across 5 rounds · 5 rounds over 6 yrs (0.8/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 29/100 | $156M | 4 mo ago | — | Muyu Li Co-Founder & COO | — | 4 patents Anti‑sclerostin biologics for osteoporosis and bone‑mass therapies | — |
| 30 | Alto Neuroscience AI-driven drug discovery platform for neurological diseases based on patients biomarkers 72Funding top 12%Patents top 25%Growth top 30%Moat top 32% All 11 signals ▾Fundingtop 12% Patentstop 25% Growthtop 30% Moattop 32% Innovationtop 33% Techtop 45% AItop 45% Globalbottom 49% Talentbottom 49% Newsbottom 44% Marketbottom 40% Funding: Raised $145M across 9 rounds · 9 rounds over 7 yrs (1.3/yr) Patents: 57 patents matched (strict assignee match) · 57 filings since 2022 vs 0 in 2017-21 rank vs industry peers · Fliar Intelligence Index 72/100 | $145M | 3 mo ago | 34 | Amit Etkin Founder & CEO | BugHerdApple iCloud MailGoogle Workspace+15 | 57 patents Neuropsychiatric therapeutics: combinatorial dopaminergic/serotonergic drugs and EEG‑guided patient selection | 1 award |
| 31 | Route 92 Medical Developer of next-generation products for neurointerventional procedures 69Funding top 14%Innovation top 18%Patents top 21%Moat top 29% All 10 signals ▾Fundingtop 14% Innovationtop 18% Patentstop 21% Moattop 29% Growthtop 32% Techtop 50% Talentbottom 49% Marketbottom 45% Newsbottom 41% Globalbottom 40% Funding: Raised $138M across 9 rounds · 9 rounds over 5 yrs (1.8/yr) Innovation: 223 patents (top 12% of patent-holders) · 137 filings since 2022 vs 82 in 2017-21 rank vs industry peers · Fliar Intelligence Index 69/100 | $138M | 5 mo ago | 51 | Tony Chou Founder & CEO | WordPress Block EditorWordPressMySQL+23 | 223 patents Neurovascular aspiration catheters for minimally invasive stroke thrombectomy | — |
| 32 | PrognomiQ Developer of tests for the detection and treatment of cancer and other diseases 57Funding top 17%Patents top 25%Moat top 28%Innovation top 31% All 9 signals ▾Fundingtop 17% Patentstop 25% Moattop 28% Innovationtop 31% Talenttop 38% Techtop 44% Globalbottom 40% Marketbottom 34% Newsbottom 18% Funding: Raised $135M across 4 rounds · 4 rounds over 4 yrs (1.0/yr) Patents: 70 patents matched (strict assignee match) · 68 filings since 2022 vs 2 in 2017-21 rank vs industry peers · Fliar Intelligence Index 57/100 | $135M | 5 mo ago | 24 24 → 44 (+83%) · sector median +32% | Philip Ma Co-Founder & CEO | WordPressMarkerApple iCloud Mail+30 | 70 patents Patents concentrated in computing, sensing & instrumentation | — |
| 33 | Endovascular Engineering Provider of mechanical thrombectomy technologies to treat venous thromboembolism 48Funding top 18%Growth top 30%Talent top 38%News top 47% All 8 signals ▾Fundingtop 18% Growthtop 30% Talenttop 38% Newstop 47% Moatbottom 48% Globalbottom 38% Marketbottom 36% Techbottom 30% Funding: Raised $122M across 3 rounds · 3 rounds over 4 yrs (0.8/yr) Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 48/100 | $122M | 2 mo ago | 19 | Mike Rosenthal Co-Founder & Chief Operating Officer | WordPressApple iCloud MailMicrosoft 365+17 | — | 3 job openings · 1 internship |
| 34 | Mirum Pharmaceuticals Developer of small molecule based therapeutics to treat rare diseases 82Funding top 17%Patents top 18%Innovation top 23%Product top 28% All 12 signals ▾Fundingtop 17% Patentstop 18% Innovationtop 23% Producttop 28% Growthtop 30% Fin. healthtop 31% Markettop 33% Moattop 35% Newstop 36% Techtop 45% Talentbottom 49% Globalbottom 47% Funding: Raised $120M across 3 rounds · 3 rounds over 8 yrs (0.4/yr) Patents: 135 patents matched (strict assignee match) · 115 filings since 2022 vs 20 in 2017-21 rank vs industry peers · Fliar Intelligence Index 82/100 | $120M | 4 mo ago | 196 196 → 465 (+137%) · sector median +32% | Christopher Peetz CEO | WordPressMySQLPHP+18 | 135 patents IBAT inhibitor drugs for treating cholestasis and pediatric liver disease | — |
| 35 | Neomorph Developer of therapeutic solutions for the treatment of multiple diseases based on protein degradation… 53Funding top 23%Moat top 28%Talent top 28%Patents top 39% All 10 signals ▾Fundingtop 23% Moattop 28% Talenttop 28% Patentstop 39% Innovationtop 44% Partnerstop 45% Marketbottom 48% Techbottom 42% Globalbottom 33% Newsbottom 20% Funding: Raised $109M across 2 rounds · 2 rounds over 6 yrs (0.3/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 25 patents rank vs industry peers · Fliar Intelligence Index 53/100 | $109M | 2 mo ago | 54 | Philip Chamberlain Co-Founder & CEO | WordPressMySQLPHP+14 | 25 patents Novel substituted piperidine-imide heterocycles for pharmaceutical active ingredient development | 5 job openings |
| 36 | Adela Developer of a platform for detection of cancer 57Funding top 22%Moat top 31%Patents top 38%Talent top 38% All 8 signals ▾Fundingtop 22% Moattop 31% Patentstop 38% Talenttop 38% Markettop 46% Innovationtop 49% Globalbottom 40% Newsbottom 22% Funding: Raised $109M across 4 rounds · 4 rounds over 5 yrs (0.8/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 15 patents rank vs industry peers · Fliar Intelligence Index 57/100 | $109M | 2 mo ago | 62 | Manish Agarwal Co-Founder | — | 15 patents Liquid biopsy nucleic acid extraction and sequencing library preparation technologies | 1 job opening · 1 partnership |
| 37 | Ray Therapeutics Developer of therapeutics for degenerative retinal diseases 48Funding top 19%Growth top 35%Tech top 40%Moat top 42% All 7 signals ▾Fundingtop 19% Growthtop 35% Techtop 40% Moattop 42% Talentbottom 49% Globalbottom 39% Marketbottom 28% Funding: Raised $106M across 6 rounds · 6 rounds over 4 yrs (1.5/yr) Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 48/100 | $106M | 1 mo ago | 10 | Paul Bresge Co-Founder & CEO | WordPressMySQLMariaDB+21 | — | — |
| 38 | Antheia Genetically engineered yeast cells to produce medicinal products 64Funding top 20%Patents top 25%Moat top 28%Innovation top 34% All 12 signals ▾Fundingtop 20% Patentstop 25% Moattop 28% Innovationtop 34% Producttop 35% Growthtop 36% Talenttop 40% Techtop 45% Newstop 45% Partnerstop 45% Globalbottom 47% Marketbottom 45% Funding: Raised $96.4M across 13 rounds · 13 rounds over 11 yrs (1.2/yr) Patents: 82 patents matched (strict assignee match) · 52 filings since 2022 vs 30 in 2017-21 rank vs industry peers · Fliar Intelligence Index 64/100 | $96M | 4 mo ago | 50 50 → 66 (+32%) · sector median +32% | Christina Smolke Co-Founder & CEO | WordPressMySQLPHP+28 | 82 patents Biotechnological production and optimization of opioid alkaloids (benzylisoquinoline and morphinan) | 2 job openings |
| 39 | AN2 Therapeutics Developer of drugs for treating infectious disease 45Funding top 19%Talent top 38%Moat top 48%Market bottom 42% All 6 signals ▾Fundingtop 19% Talenttop 38% Moattop 48% Marketbottom 42% Globalbottom 32% Newsbottom 24% Funding: Raised $92.0M across 3 rounds · 3 rounds over 7 yrs (0.4/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 45/100 | $92M | 3 mo ago | 35 35 → 37 (+6%) · sector median +32% | Eric Easom Co-Founder & CEO & President | — | — | — |
| 40 | TEMPEST THERAPEUTICS Developing targeted, immune-mediated oral cancer therapies for broad patient benefit 21Funding top 28%News top 36%Growth top 42%Tech top 49% All 9 signals ▾Fundingtop 28% Newstop 36% Growthtop 42% Techtop 49% Moatbottom 43% Talentbottom 41% Globalbottom 39% Marketbottom 23% Fin. healthbottom 13% Funding: Raised $88.2M across 4 rounds · 4 rounds over 15 yrs (0.3/yr) News: 19 BI events in 12 mo (of 57 tracked, 7 types) · +6% YoY rank vs industry peers · Fliar Intelligence Index 21/100 | $88M | 2 mo ago | 19 | Stephen B Chief Executive Officer | DrupalPHPparticles.js+25 | — | — |
| 41 | Calyxo Standalone nephrology hospital 69Funding top 19%Patents top 24%News top 25%Innovation top 31% All 9 signals ▾Fundingtop 19% Patentstop 24% Newstop 25% Innovationtop 31% Techtop 44% Moattop 44% Talentbottom 49% Marketbottom 47% Globalbottom 42% Funding: Raised $82.7M across 4 rounds · 4 rounds over 4 yrs (1.0/yr) Patents: 51 patents matched (strict assignee match) · 34 filings since 2022 vs 5 in 2017-21 rank vs industry peers · Fliar Intelligence Index 69/100 | $83M | 2 mo ago | 48 | Joe Catanese President & CEO | WordPress Block EditorwpBakeryWordPress+35 | 51 patents Minimally invasive urological devices for kidney stone aspiration, irrigation, and catheter steering | 1 award |
| 42 | Emboline Developer of an aortic embolic protection device 48Funding top 22%Moat top 26%Innovation top 28%Patents top 29% All 9 signals ▾Fundingtop 22% Moattop 26% Innovationtop 28% Patentstop 29% Talenttop 38% Techbottom 44% Newsbottom 42% Globalbottom 40% Marketbottom 28% Funding: Raised $81.9M across 5 rounds · 5 rounds over 8 yrs (0.6/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 112 patents rank vs industry peers · Fliar Intelligence Index 48/100 | $82M | 3 mo ago | 13 13 → 23 (+77%) · sector median +32% | Amir Belson Founder & CTO | WordPressMySQLPHP+16 | 112 patents Embolic protection and delivery devices for cardiovascular catheter procedures | — |
| 43 | ClearNote Health Developer of non-invasive cancer detection methods 40Moat top 22%Funding top 36%Market top 50%Talent bottom 49% All 5 signals ▾Moattop 22% Fundingtop 36% Markettop 50% Talentbottom 49% Globalbottom 36% Moat: Editorial + unicorn rating 8/10 · Soonicorn Funding: Raised $70.0M across 2 rounds · 2 rounds over 5 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 40/100 | $70M | 0 mo ago | 45 | Dave Mullarkey Chief Executive Officer | — | — | — |
| 44 | Aureka Biotechnologies Biotech company digitizing therapeutic discovery to manage human health 55Funding top 20%AI top 35%Talent top 38%Market bottom 37% All 5 signals ▾Fundingtop 20% AItop 35% Talenttop 38% Marketbottom 37% Globalbottom 36% Funding: Raised $58.0M across 2 rounds · 2 rounds over 1 yrs (2.0/yr) AI: Product described with: ai-based, artificial intelligence rank vs industry peers · Fliar Intelligence Index 55/100 | $58M | 1 mo ago | — | Weian Zhao Co-Founder & CEO | — | — | — |
| 45 | Cartography Biosciences Provider of a platform to discover immunotherapeutics 24Funding top 23%Moat top 31%News top 39%Talent bottom 49% All 6 signals ▾Fundingtop 23% Moattop 31% Newstop 39% Talentbottom 49% Globalbottom 37% Marketbottom 27% Funding: Raised $57.0M across 2 rounds · 2 rounds over 4 yrs (0.5/yr) Moat: Editorial + unicorn rating 8/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 24/100 | $57M | 1 mo ago | 10 | Howard Chang Co-Founder | — | — | — |
| 46 | ReviR Therapeutics Developer of RNA-based therapeutics for multiple diseases 35Funding top 26%AI top 45%Moat top 47%Talent bottom 49% All 8 signals ▾Fundingtop 26% AItop 45% Moattop 47% Talentbottom 49% Marketbottom 36% Globalbottom 36% Techbottom 31% Newsbottom 18% Funding: Raised $54.0M across 3 rounds · 3 rounds over 4 yrs (0.8/yr) AI: Product described with: machine learning rank vs industry peers · Fliar Intelligence Index 35/100 | $54M | 1 mo ago | 29 | Yang Li Co-Founder | UbuntuElement UIVue.js+6 | — | 1 partnership |
| 47 | LTZ Therapeutics Developer of immunotherapies to treat cancer and other diseases 35Funding top 26%Moat top 39%Talent bottom 49%Market bottom 40% All 5 signals ▾Fundingtop 26% Moattop 39% Talentbottom 49% Marketbottom 40% Globalbottom 36% Funding: Raised $47.0M across 4 rounds · 4 rounds over 4 yrs (1.0/yr) Moat: Editorial + unicorn rating 7/10 · 10 curated direct competitors tracked rank vs industry peers · Fliar Intelligence Index 35/100 | $47M | 1 mo ago | 23 | Martin Treder Co-Founder | — | — | 2 job openings |
| 48 | Signos Provider of a wearable device for blood glucose pattern monitoring 42Tech top 20%Funding top 25%Moat top 39%Customers top 44% All 10 signals ▾Techtop 20% Fundingtop 25% Moattop 39% Customerstop 44% Producttop 46% Talentbottom 49% Marketbottom 40% Globalbottom 36% Growthbottom 31% Newsbottom 22% Tech: 52 technologies across 6/8 capability areas · Cloud: Amazon Cloudfront, Amazon Web Services Funding: Raised $37.0M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 42/100 | $37M | 0 mo ago | 30 | Sharam Fouladgar-Mercer Co-Founder & CEO | Webflow EcommerceWebflowGSAP+27 | — | — |
| 49 | Triomics Provider of clinical research and clinical trial tracking software 60AI top 20%Funding top 26%Talent top 38%Moat top 39% All 8 signals ▾AItop 20% Fundingtop 26% Talenttop 38% Moattop 39% Techtop 40% Growthtop 47% Globalbottom 43% Marketbottom 35% AI: Classified as an AI company Funding: Raised $28.9M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 60/100 | $29M | 0 mo ago | 29 | Hrituraj Singh Co-Founder & CTO | WixSentryEnvoy+20 | — | — |
| 50 | OncoSynergy Developer of resistance mechanism inhibitors to treat cancer 11Funding top 28%Moat top 32%Patents bottom 48%Global bottom 42% All 6 signals ▾Fundingtop 28% Moattop 32% Patentsbottom 48% Globalbottom 42% Innovationbottom 33% Marketbottom 18% Funding: Raised $26.7M across 7 rounds · 7 rounds over 8 yrs (0.9/yr) Moat: Editorial + unicorn rating 5/10 · IP moat: 26 patents rank vs industry peers · Fliar Intelligence Index 11/100 | $27M | 1 mo ago | 3 | — | — | 26 patents Patents concentrated in chemistry & materials | — |
Top 12 Life Sciences companies in California
#1
Series E · Fremont, California · founded 2016 · 197 employees$680Mraised▾
Series E · Fremont, California · founded 2016 · 197 employees
Provider of implantable brain-computer interfaces. It offers flagship product the N1 Implant the Link which is a coin-sized device designed to decode neural signals and enable users to control digital devices using only their thoughts. It also has an experimental device called Blindsight to restore vision in individuals with optic nerve damage by directly stimulating the visual cortex.
Fliar Intelligence Index™ 78how this company ranks against its industry peers
Funding
top 15%Patents
top 25%Moat
top 25%Innovation
top 27%Talent
top 28%Market
top 33%Funding: Raised $680M across 6 rounds · 6 rounds over 9 yrs (0.7/yr) · Last round Series E (May 2026)
Patents: 97 patents matched (strict assignee match) · 62 filings since 2022 vs 35 in 2017-21 · Latest publication 2026
Moat: Editorial + unicorn rating 9/10 · IP moat: 97 patents · Unicorn
Audience (LinkedIn): 414k LinkedIn followers — 31.0% of this cohort's audience
Activity (LinkedIn): 1 product launches announced in 12 mo
Funding rounds
- May 2026Series E—
- May 2025Series E$650M
- Nov 2023Series D$43M
- Aug 2023Series D$323.2M
Founders & team
Investors
Founders Fund, Advaita Capital, Setcoin Group, MarketX, Ipo Club, Type One Ventures
Tech stack
Amazon AlbAmazon CloudfrontAmazon S3Amazon SesAmazon Web ServicesApple Icloud Mail
#2
Public · San Francisco, California · founded 2012 · 21 employees$420.1Mraised▾
Public · San Francisco, California · founded 2012 · 21 employees
Developer of therapeutics for orthopedic diseases. It offers a lead candidate NOV004 which is an anabolic peptide engineered to target and concentrate at the bone fracture site and also helps in spinal fusion and osteogenesis Imperfecta.
Fliar Intelligence Index™ 53how this company ranks against its industry peers
Funding
top 13%Growth
top 37%Tech
top 44%Moat
top 48%Talent
bottom 49%Market
bottom 37%Funding: Raised $420M across 7 rounds · 7 rounds over 12 yrs (0.6/yr) · Last round Post IPO (May 2026)
Growth: Web rank 50,000,000 → 5,000,000 YoY · Fresh capital in last 24 mo
Tech: 37 technologies across 3/8 capability areas · Cloud: Amazon Web Services, Cloudflare · Security: Cloudflare Bot Management, Hsts
Audience (LinkedIn): 4k LinkedIn followers
Activity (LinkedIn): 1 product launches · 1 partnerships (incl. LifeSci Capital) announced in 12 mo
Funding rounds
- May 2026Post IPO$187M
- Feb 2020Post IPO$125M
- May 2018Series B$84.5M
- Feb 2017Series A$7.6M
Founders & team
Investors
Breakout Labs, Dolby Family Ventures, Takeda, Pfizer Venture Investments, Takeda Ventures, Sequoia Capital
Tech stack
Acquia Cloud PlatformAcquia Cloud Site FactoryAdobe AnalyticsAdobe Experience Platform Identity ServiceAdobe Experience Platform LaunchAmazon Web Services
#3
Series E · Campbell, California · founded 2015 · 90 employees$496Mraised▾
Series E · Campbell, California · founded 2015 · 90 employees
Provider of access catheters for cardiovascular diagnosis and treatment. The catheters are used in deep navigation into the blood vessels of the brain to prevent strokes. The flagship product ZOOM Aspiration System is a family of products designed to facilitate clot removal during ischemic stroke.
Fliar Intelligence Index™ 82how this company ranks against its industry peers
Funding
top 14%Patents
top 15%Innovation
top 18%Moat
top 26%Growth
top 27%Tech
top 36%Funding: Raised $496M across 4 rounds · 4 rounds over 7 yrs (0.6/yr) · Last round Series E (Mar 2026)
Patents: 261 patents matched (strict assignee match) · 225 filings since 2022 vs 36 in 2017-21 · Latest publication 2026
Innovation: 261 patents (top 10% of patent-holders) · 225 filings since 2022 vs 36 in 2017-21
Audience (LinkedIn): 37k LinkedIn followers — 2.8% of this cohort's audience
Funding rounds
- Mar 2026Series E$100M
- Jul 2024Series E$150M
- Jul 2021Series D$260M
- Dec 2019Series C$86M
Founders & team
Investors
Delos Capital, HealthCor Partners, Ally Bridge Group, Rock Springs Capital, Ascension, Innovatus Capital Partners
Tech stack
Apple Icloud MailAutoptimizeCdnjsCloudflareCloudflare Bot ManagementContact Form 7
#4
Public · Menlo Park, California · founded 2016 · 491 employees$2Braised▾
Public · Menlo Park, California · founded 2016 · 491 employees
Developer of a screening platform for circulating tumor DNA to detect cancer. The company is developing a test called "Galleri" a pan-cancer screening test by measuring circulating nucleic acids in the blood. Its proprietary platform uses the ultra-deep sequencing technique to measure levels of circulating tumor DNA in the patient's blood.
Fliar Intelligence Index™ 78how this company ranks against its industry peers
Patents
top 13%Tech
top 16%News
top 17%Funding
top 20%Innovation
top 25%Growth
top 36%Patents: 899 patents matched (strict assignee match) · 523 filings since 2022 vs 371 in 2017-21 · Latest publication 2026
Tech: 51 technologies across 6/8 capability areas · Cloud: Amazon Alb, Amazon Cloudfront · Devops: Nginx
News: 11 BI events in 12 mo (of 75 tracked, 14 types) · +83% YoY · 5 high-value events (IPO/M&A/funding/contracts) in 12 mo
Audience (LinkedIn): 113k LinkedIn followers — 8.4% of this cohort's audience
Funding rounds
- Oct 2025Post IPO$325M
- Nov 2019Series D$390M
- May 2018Series C$300M
- Jun 2017Series B—
Founders & team
Investors
PSP Investments, CPP Investments, Illumina, Arch Venture Partners, Johnson & Johnson Innovation, McKesson Ventures
Tech stack
Amazon CloudfrontAmazon S3Amazon SesAmazon Web ServicesApolloApple Icloud Mail
#5
Public · San Francisco, California · founded 2016 · 122 employees$158Mraised▾
Public · San Francisco, California · founded 2016 · 122 employees
Developer of cell and gene therapies for patients living with incurable diseases. The company has developed its proprietary synthetic biology platform to produce cell and gene therapies for cancer treatment. The company's pipeline is comprised of cell therapies engineered with Gene Circuits to target difficult to treat liquid and solid tumors. It offers CAR-NK-based therapies for multiple cancer and tumors.
Fliar Intelligence Index™ 45how this company ranks against its industry peers
Product
top 14%Funding
top 21%Talent
top 22%Tech
top 32%Innovation
top 34%News
bottom 43%Product: 4 distinct product lines · Company stage: Public
Funding: Raised $158M across 8 rounds · 8 rounds over 8 yrs (1.0/yr) · Last round Post IPO (May 2026)
Talent: Analyst team rating 5/5 · 3 named leaders on record · 3 C-suite/founder profiles curated
Audience (LinkedIn): 12k LinkedIn followers
Funding rounds
- May 2026Post IPO$40M
- Dec 2024Post IPO$37.6M
- Dec 2024Post IPO$10M
- Jun 2024Grant (prize money)$8M
Founders & team
Investors
Matrix Partners China, Mirae Asset, Ridgeback Capital Management, Lux Capital, Gaingels, KB Investment
Tech stack
Acquia Cloud PlatformAcquia Cloud Site FactoryAddthisAdobe AnalyticsAdobe Experience Platform Identity ServiceAdobe Experience Platform Launch
#6
Series E · San Ramon, California · founded 2003 · 20 employees$181.4Mraised▾
Series E · San Ramon, California · founded 2003 · 20 employees
BioVentrix develops clinical solutions for treating heart failure patients. It provides PliCath HF, an epicardial catheter-based ventricular reconstruction device. Product is not commercially available.
Fliar Intelligence Index™ 40how this company ranks against its industry peers
Funding
top 16%Moat
top 19%Patents
top 36%Talent
top 38%Innovation
top 43%Global
bottom 45%Funding: Raised $181M across 25 rounds · 25 rounds over 22 yrs (1.1/yr) · Last round Series E (Apr 2026)
Moat: Editorial + unicorn rating 8/10 · IP moat: 185 patents · Soonicorn
Patents: 185 patents matched (strict assignee match) · 29 filings since 2022 vs 71 in 2017-21 · Latest publication 2026
Audience (LinkedIn): 5k LinkedIn followers
Activity (LinkedIn): 1 partnerships (incl. BioVentrix, Inc.) announced in 12 mo
Funding rounds
- Apr 2026Series E$705K
- Oct 2024Series E$6.7M
- Mar 2024Series E$3.6M
- Apr 2023Series E$48.5M
Founders & team
Investors
Taglich Brothers, Andera Partners, Cormorant Asset Management, Squarepoint Capital, Richmond Brothers, Telegraph Hill Partners
Tech stack
BootstrapCloudwaysGoogle AnalyticsGsapIsotopeJquery
#7
Series C · San Francisco, California · founded 2021 · 35 employees$250Mraised▾
Series C · San Francisco, California · founded 2021 · 35 employees
Developer of small-molecule therapeutics for cancer treatment. It provides a lysine-targeted covalency platform to develop therapies against known drug targets for oncology.
Fliar Intelligence Index™ 60how this company ranks against its industry peers
Funding
top 15%Talent
top 28%Moat
top 31%Growth
top 35%Tech
top 49%Market
bottom 41%Funding: Raised $250M across 3 rounds · 3 rounds over 4 yrs (0.8/yr) · Last round Series C (Apr 2026)
Talent: 3 named leaders on record · 3 C-suite/founder profiles curated
Moat: Editorial + unicorn rating 8/10 · Soonicorn · 10 curated direct competitors tracked
Audience (LinkedIn): 7k LinkedIn followers
Funding rounds
- Apr 2026Series C$108M
- Nov 2023Series B$175M
- May 2022Series A$75M
Founders & team
Investors
Orbimed, Third Rock Ventures, EcoR1, Novo Holdings, Cormorant Capital, RA Capital Management
Tech stack
All In One SeoAmazon Web ServicesApple Icloud MailBugherdCdnjsCloudflare
#8
Series D · Stanford, California · founded 2013 · 50 employees$157.1Mraised▾
Series D · Stanford, California · founded 2013 · 50 employees
Developer of a wearable non-invasive neuromodulation device. The company has developed a neuromodulation device that aims to provide relief of hand tremors in adults with essential tremors. It combines a watch-like device with an implantable sensor that externally stimulates peripheral nerves to reduce the same. The company has also developed a portable medical device with sensors to monitor the physical movement of a patient wearing or carrying the device.
Fliar Intelligence Index™ 60how this company ranks against its industry peers
Funding
top 17%Product
top 21%Innovation
top 22%Patents
top 26%Moat
top 26%Talent
top 38%Funding: Raised $157M across 7 rounds · 7 rounds over 13 yrs (0.5/yr) · Last round Conventional Debt (Apr 2026)
Product: 6 distinct product lines · Company stage: Series D
Innovation: 243 patents (top 5% of patent-holders) · 127 filings since 2022 vs 106 in 2017-21 · 6 product lines
Audience (LinkedIn): 16k LinkedIn followers
Activity (LinkedIn): 1 awards announced in 12 mo
Funding rounds
- Apr 2026Conventional Debt$50M
- Oct 2025Series D$50M
- Dec 2024Series D$50M
- May 2022Series D—
Founders & team
Investors
Google Ventures, Novartis, Johnson & Johnson Innovation, Baird Capital, Lux Capital, Lightstone Ventures
Tech stack
AccessibeAmplitudeApple Icloud MailCdnjsChoicesCloudflare
#9
Series C · San Diego, California · founded 2019 · 50 employees$206.2Mraised▾
Series C · San Diego, California · founded 2019 · 50 employees
Provider of AI-driven drug discovery platform for the treatment of cancer. It offers an AI driven discovery platform and has discovered two candidates known as IAM-H1, a highly selective and brain penetrant inhibitor of HER2 and its oncogenic mutants, and IAM-C1 a potential first-in-class selective dual CDK2/4 inhibitor to address unmet needs in terms of therapeutic window and treatment resistance in cell cycle driven cancers.
Fliar Intelligence Index™ 60how this company ranks against its industry peers
Funding
top 15%AI
top 26%Moat
top 31%Talent
top 38%Growth
top 45%Market
bottom 43%Funding: Raised $206M across 5 rounds · 5 rounds over 5 yrs (1.0/yr) · Last round Series C (Apr 2026)
AI: Classified as an AI company · Product described with: ai driven, ai-driven
Moat: Editorial + unicorn rating 8/10 · Soonicorn · 10 curated direct competitors tracked
Funding rounds
- Apr 2026Series C$27.8M
- Nov 2025Series C$100M
- Apr 2024Series B$50M
- Oct 2023Series B$103.2M
Founders & team
Investors
Ascenta Capital, Abingworth, Nvidia, Illumina Ventures, Shanda, Catalio Capital Management
Tech stack
Apple Icloud MailCloudflareDocusignGoogle Font ApiGoogle Hosted LibrariesHsts
#10
Science 🦄Series C · Alameda, California · founded 2021 · 76 employees$360Mraised▾
Science 🦄
Series C · Alameda, California · founded 2021 · 76 employees
Provider of online science magazine. They specialize in offering content in various topics such as science for patients,technologies and much more.
Fliar Intelligence Index™ 72how this company ranks against its industry peers
Funding
top 13%Patents
top 20%Moat
top 24%Innovation
top 33%Growth
top 35%Market
top 38%Funding: Raised $360M across 3 rounds · 3 rounds over 2 yrs (1.5/yr) · Last round Series C (Feb 2026)
Patents: 245 patents matched (strict assignee match) · 102 filings since 2022 vs 115 in 2017-21 · Latest publication 2026
Moat: IP moat: 245 patents · Unicorn · 9 curated direct competitors tracked
Audience (LinkedIn): 14k LinkedIn followers
Hiring (LinkedIn): 3 hiring posts in 12 mo (public) · momentum +3 · hiring: Senior Regulatory Specialist, Customer Service Engineer
Activity (LinkedIn): 1 awards announced in 12 mo
Funding rounds
- Feb 2026Series C$230M
- Mar 2025Series C$104M
- May 2024Series B$26M
Founders & team
Investors
Khosla Ventures, Lightspeed Venture Partners, Y Combinator, Quiet Capital, In-Q-Tel, Olive Capital
Tech stack
Apple Icloud MailAstroChakra UiDocusignEmotionGoogle Workspace
#11
Public · Sacramento, California · founded 2020 · 33 employees$268Mraised▾
Public · Sacramento, California · founded 2020 · 33 employees
Developer of therapeutic options for chronic inflammatory disorders. The pipeline drug candidates include v for rosacea, and atopic dermatitis, RORγt for psoriasis, MRGPRX2 for pruritus, and PKCϴ for atopic dermatitis. The company uses a tissue-based screening platform that helps in the drug development of inflammatory diseases.
Fliar Intelligence Index™ 60how this company ranks against its industry peers
Growth
top 16%Funding
top 18%News
top 25%Tech
top 47%Fin. health
top 47%Moat
top 47%Growth: Revenue +86% YoY · Fresh capital in last 24 mo
Funding: Raised $268M across 6 rounds · 6 rounds over 6 yrs (1.0/yr) · Last round Post IPO (Feb 2026)
News: 15 BI events in 12 mo (of 26 tracked, 6 types) · +650% YoY · 14 high-value events (IPO/M&A/funding/contracts) in 12 mo
Audience (LinkedIn): 5k LinkedIn followers
Activity (LinkedIn): 2 product launches · 1 partnerships (incl. Maruho Co Ltd.) announced in 12 mo
Funding rounds
- Feb 2026Post IPO$125M
- Oct 2024Series C$115M
- Jun 2023Series B$7.5M
- Mar 2023Series B$57.5M
Investors
Andera Partners, Life Sciences Partners, Pivotal bioVenture Partners, RA Capital Management, Sectoral, RTW Investments
Tech stack
Amazon Web ServicesAosApache Http ServerBootstrapCloudflareCloudflare Bot Management
#12
Series B · San Diego, California · founded 2023$480Mraised▾
Series B · San Diego, California · founded 2023
Developer of therapeutics for immune-mediated inflammatory and fibrotic diseases. The company’s Mirador360 precision development engine leverages the latest advances in human genetics and cutting-edge data science to rapidly advance new precision medicines for patients living with chronic immune-mediated inflammatory and fibrotic diseases.
Fliar Intelligence Index™ 50how this company ranks against its industry peers
Funding
top 15%Growth
top 35%Moat
top 42%Tech
top 44%Product
top 49%Talent
bottom 49%Funding: Raised $480M across 3 rounds · 3 rounds over 3 yrs (1.0/yr) · Last round Series B (Jan 2026)
Growth: Fresh capital in last 24 mo
Moat: Editorial + unicorn rating 4/10 · Soonicorn · 10 curated direct competitors tracked
Audience (LinkedIn): 119 LinkedIn followers
Funding rounds
- Jan 2026Series B$250M
- Feb 2024Series A$400M
- Dec 2023Seed$80M
Founders & team
Investors
Arch Venture Partners, Orbimed, Fairmount Partners, Sanofi, Point72 Ventures, Farallon Capital Management
Tech stack
AddtoanyAmazon CloudfrontAmazon Web ServicesApache Http ServerApple Icloud MailCookiebot
Funding & investor landscape
$153.4Btotal disclosed funding
2,822companies funded
10,407disclosed rounds
41rounds last 90 days
Most active investors
Notable founders
Dongjin Seo
Co-Founder · Neuralink
Elon Musk
Co-Foudner & CEO & Owner · Neuralink
Dirk Thye
CEO · Quince Therapeutics
Dr Hopkins
Co-founder · Imperative Care
Fred Khosravi
Co-Founder & CEO · Imperative Care
Bob Ragusa
Chief Executive Officer · GRAIL
Jim Collins
Co-Founder · Senti Bio
Wilson Wong
Co-Founder · Senti Bio
Lon Annest
Co-Founder · Bioventrix
David R
Co-CEO · Bioventrix
Matt Jacobson
Co-Founder · Terremoto
Jack Taunton
Co-Founder · Terremoto
Prism market signals · United States · country-scoped Prism corpus, 1,465,538 docs
Market landscape — 10 sub-themes by coverage
Share of Life Sciences coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
RESEARCH IN CALIFORNIA · Health & Bio
How research on Biotechnology in California is moving
A read on the academic research around Biotechnology in California — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 465 papers.
California's UC system (Davis, Berkeley, Irvine) leads CRISPR and genetic engineering research across 465 papers, with breakthroughs dominating and a cautiously optimistic tone (mean stance 0.52).
465 papers · stance +0.52 · 47% breakthrough · 15% concern
top institutions
- University of California, Davis74
- University of California, Berkeley57
- University of California, Irvine51
- University of California, San Francisco49
- University of California, Los Angeles43
leading researchers
Suhas Sureshchandra · A. R. Kurhe · R. R. Raut · S. S. Mirza · G. D. Suryawanshi · Blake A. Simmons
prism intelligence · tone & topics
90% positive · 4% critical tone
Medical ResearchHealthPharmaceuticalsBiologyAgricultureGenetics
▲
Breakthroughs187 · 40%
▼ 43%→39% share
▼0.9× share momentum0 median citations64% since 2021mostly empirical
Gene-editing research is surging — Gene papers tripled (6→18) and three genomics sub-topics newly emerged.
rising sub-themes (early→recent)
- Gene6→18
- Transcription (linguistics)2→9
- Gene expression3→9
- Mutant2→6
- DNA methylation4→8
Newly emergingGene knockdown 0→6 · Genome 0→6 · Genomics 0→6
Landmark RNA-programmed genome editing in human cells · 2,139 cites
◆
Advancements154 · 33%
▼ 37%→32% share
▼0.9× share momentum0 median citations64% since 2021mostly empirical
Vermicompost-related biotech is newly emerging — Compost, Eisenia fetida, and Vermicompost each debuted with 6–7 papers.
rising sub-themes (early→recent)
- Gene1→6
- DNA damage1→5
- Population1→4
- Transcriptome1→4
- Bacteria1→3
Newly emergingCompost 0→7 · Eisenia fetida 0→6 · Vermicompost 0→6
Landmark Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated · 2,029 cites
▼
Concerns60 · 13%
▼ 13%→12% share
▼0.9× share momentum0 median citations63% since 2021mostly empirical
Cancer research is a newly emerging concern — Cancer and Cancer cell sub-topics both debuted with 3 papers each.
rising sub-themes (early→recent)
- Population2→4
Newly emergingCancer 0→3 · Cancer cell 0→3 · Public health 0→3
Landmark Beneficial Biofuels—The Food, Energy, and Environment Trilemma · 1,582 cites
Common questions
How many Life Sciences companies are there in California, United States?
Radar tracks 5090 indexable Life Sciences companies headquartered in California, United States that meet our profile-completeness bar.
What is the total funding raised by Life Sciences companies in California, United States?
The Life Sciences companies in California, United States on this list have raised a combined $153.4B in disclosed equity funding across 2822 funded companies.
Which is the highest-funded Life Sciences company in California, United States?
GRAIL is the highest-funded Life Sciences company in California, United States, with $2B in disclosed equity funding.
How many Life Sciences companies in California, United States are funded?
2822 of the 5090 Life Sciences companies in California, United States on this list have disclosed at least one equity funding round.
How many Life Sciences unicorns are there in California, United States?
20 Life Sciences companies in California, United States on this list are valued at $1B or more.
Who are the top investors in California, United States Life Sciences companies?
The most active investors in California, United States Life Sciences companies on this list include HHS, Y Combinator, National Science Foundation, Orbimed, NIH.
Riya SenguptaFinancials
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.