Best Life Sciences Companies in Denver, United States
The 82 best Life Sciences companies in Denver, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Inscripta.
Our analysis of 164 Life Sciences companies
$34.7b in tracked funding; 83% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Life Sciences companies in Denver
| # | Company | Disclosed funding | Last round | Employees | Founder | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|
| 1 | Inscripta Developer of gene editing technology for research | $499M | 42 mo ago | 176 | Andrew Garst Co-Founder | Top 10M | 654 patents CRISPR-based genome editing platforms and microbial metabolic engineering for isoprenoid production | — |
| 2 | Rezolute Developing transformative therapies for rare diseases, focusing on hyperinsulinism (HI) | $191M | 68 mo ago | 51 51 → 73 (+43%) | Nevan Elam Co-Founder & CEO | Top 10M | 89 patents Therapeutic antibodies targeting insulin receptor and plasma kallikrein inhibitor drugs. | — |
| 3 | BioIntelliSense Developer of medical-grade wearable devices and data services for patient monitoring 50Funding top 21%Moat top 21%Patents top 25%Innovation top 26% All 10 signals ▾Fundingtop 21% Moattop 21% Patentstop 25% Innovationtop 26% Producttop 35% Talenttop 38% Techbottom 49% Globalbottom 40% Marketbottom 36% Customersbottom 3% Funding: Raised $82.0M across 4 rounds · 4 rounds over 8 yrs (0.5/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 47 patents rank vs industry peers · Fliar Intelligence Index 50/100 | $82M | 6 mo ago | 26 | James Mault Co-Founder&CEO | Top 10M | 47 patents Patents concentrated in health & consumer products | — |
| 4 | Remedy Robotics Developer of endovascular robots | $35M | 8 mo ago | 12 12 → 21 (+75%) | — | Top 50M | 51 patents Robotic navigation and imaging systems for endovascular catheter procedures | — |
| 5 | Certadose Innovative dosing solutions to eliminate medication errors and improve patient safety | $20M | 78 mo ago | — | Caleb Hernandez Do Facep President | — | — | — |
| 6 | ImmunoMolecular Therapeutics Developer of immunomodulatory therapeutics for diabetes treatments | $18M | 67 mo ago | 9 | Aaron Michels Co-founder & Chief Scientific Officer | — | — | — |
| 7 | Atkins Provider of low-carb products for weight loss | $15M | 185 mo ago | 241 | Robert Atkins Founder | Top 500k | — | — |
| 8 | ClinOne Mobile app for clinical trial engagement | $12M | 31 mo ago | 27 | Rob Bohacs Co-Founder | — | — | — |
| 9 | Securisyn Developer of airway management system for ventilated patients | $11M | 10 mo ago | 10 | Arthur Kanowitz Co-Founder & CEO | — | — | — |
| 10 | Medsurant Monitoring Intraoperative neurophysiologial monitoring (IONM) services to hospitals and physicians. | $10M | 182 mo ago | 40 | — | — | — | — |
| 11 | Exum Provider of tools and instruments for research 8Funding top 45%Tech top 45%Growth bottom 42%Global bottom 32% All 7 signals ▾Fundingtop 45% Techtop 45% Growthbottom 42% Globalbottom 32% Moatbottom 22% Marketbottom 16% Fin. healthbottom 8% Funding: Raised $9.9M across 8 rounds · 8 rounds over 7 yrs (1.1/yr) Tech: 23 technologies across 5/8 capability areas · Cloud: Cloudflare rank vs industry peers · Fliar Intelligence Index 8/100 | $10M | 6 mo ago | 15 | — | Top 10M | — | 1 launch |
| 12 | ViroCyt Technology for virus quantification. | $9M | 132 mo ago | 11 | Robert Kline ex-President & CEO | — | 19 patents Automated optical alignment and virus-size particle detection in flow cytometry. | — |
| 13 | Xtremity Developer of prosthetic socket systems to restore amputees mobility | $8M | 44 mo ago | 11 | — | — | — | — |
| 14 | MuscleSound Point-of-care software for malnutrition assessment and improved patient care 14Moat top 25%Innovation top 46%Patents top 48%Product top 48% All 9 signals ▾Moattop 25% Innovationtop 46% Patentstop 48% Producttop 48% Fundingtop 49% Talentbottom 49% Globalbottom 37% Techbottom 21% Marketbottom 20% Moat: Editorial + unicorn rating 6/10 · IP moat: 34 patents Innovation: 34 patents (top 39% of patent-holders) · 11 filings since 2022 vs 16 in 2017-21 rank vs industry peers · Fliar Intelligence Index 14/100 | $8M | 7 mo ago | 6 | Stephen Kurtz Chairman & CEO | — | 34 patents Non‑invasive measurement of muscle metabolism and architecture for fitness/rehab monitoring | — |
| 15 | Colorado Therapeutics Innovative crosslinking technology for soft tissue repair, improving patient outcomes | $7M | 110 mo ago | 2 | Joseph Horn Founder & CEO | — | — | — |
| 16 | RheumaGen Developer of therapeutics for auto-immune diseases | $5M | 17 mo ago | 4 | Richard Freed Co-Founder & CEO | Top 50M | — | — |
| 17 | Covalent Data Innovation management platform powering the entire innovation lifecycle, from concept to commercialization | $5M | 122 mo ago | 4 | — | — | — | — |
| 18 | Xtend Release Patented, timed-release delivery system innovator for nutritional supplements and pharmaceuticals | $5M | 125 mo ago | 5 | — | — | — | — |
| 19 | Pluto Biosciences Cloud-based research data management tool for scientists | $5M | 14 mo ago | 9 | Rani Powers Founder & CEO | Top 10M | — | 1 launch |
| 20 | HeartHero Developing next-generation AEDs to improve survival rates from cardiac arrest | $4M | 11 mo ago | 6 | — | — | 35 patents Advanced AED devices integrating synchronized cardioversion, drug delivery, and adaptive power management | — |
| 21 | ClearSight Intra-ocular technology with micro-patterned membrane for posterior lens capsule opacification treatment | $4M | 74 mo ago | 3 | Kevin Cuevas Founder | — | 7 patents Monolithic intra‑ocular lens design and manufacturing for cataract surgery | — |
| 22 | Topogen Provider of products and services for researchers | $3M | 70 mo ago | 7 | — | Top 10M | 3 patents Diagnostic methods and kits for detecting bladder cancer biomarkers | — |
| 23 | CryoMass Technologies Manufacturer of cryogenic refinement systems for cannabis and hemp biomass | $2M | 56 mo ago | 64 | — | — | 16 patents Patents concentrated in transport & manufacturing processes | — |
| 24 | Agritek Holdings Integrated business for cultivation of cannabis and supply of medical marijuana products | $2M | 106 mo ago | 2 | — | — | — | — |
| 25 | Vaporox Developer of medical device for the wound treatment | $2M | 36 mo ago | 10 | Alan Sage CEO & President | Top 10M | 18 patents Multistage vaporizer devices for precise medical aerosol drug delivery | 1 launch |
| 26 | Aegis Spine Medical device company innovating spine, orthopedics, and minimally invasive technologies | $2M | 55 mo ago | 21 | — | — | 20 patents Adjustable spinal fixation plates and related surgical implant components | — |
| 27 | Eleven P15 Developer of genetically-targeted therapeutic for pulmonary fibrosis | $2M | 79 mo ago | — | David Schwartz Founder | — | 5 patents Early detection of pulmonary fibrosis via circulating biomarker assays | — |
| 28 | Even Manufacturer of dietary supplements to manage body immunity power & other health related issues | $2M | 63 mo ago | 11 | Grant Hosking Co-Founder | — | — | — |
| 29 | NewLeaf Brands Manufacturer of recreational and medicinal cannaboidal products | $1M | 73 mo ago | — | David Bartch CEO | — | — | — |
| 30 | The BioCollective Microbiome research products and services for advancing scientific discovery | $1M | 76 mo ago | 6 | Martha Carlin Co-Founder & CEO | — | 5 patents Probiotic therapeutic formulations and microbiome sampling/collection device technologies. | — |
| 31 | SciLogica Developer of a continuous blood parameter monitoring platform for critical care healthcare | $1M | 46 mo ago | 8 | — | — | 52 patents Calibration, sterilization, and polymer matrix design for chemical/biological analyte sensors | — |
| 32 | enlightenVue Manufacturer of endoscopy-related devices for surgery | $1M | 50 mo ago | 2 | — | — | 41 patents Advanced illuminated, variable-profile endoscopic tips for minimally invasive diagnostic and therapeutic procedures. | — |
| 33 | Intelligent Imaging Innovations Advanced microscopy systems and software solutions for biological research and analysis | $956K | 17 mo ago | 30 30 → 41 (+37%) | Karl Kilborn Owner | Top 10M | 59 patents Advanced light-sheet microscopy illumination systems and image registration algorithms | — |
| 34 | Analyte Logic Sensor system for Postoperative Opioid-Induced Respiratory Depression prevention | $700K | 148 mo ago | 5 | Nicholas L. Taro Founder | — | — | — |
| 35 | Snoasis Medical Biologic solutions for clinicians, delivering trusted results in regenerative dentistry | $660K | 55 mo ago | 20 | — | — | — | — |
| 36 | Immunocept Medical Products Hemofilter designed for sepsis | $530K | 106 mo ago | — | James Matson Founder | — | — | — |
| 37 | Khona Scientific Developer of biosynthetic production platform for complex natural product compounds | $511K | 14 mo ago | 2 | Jordan Buck Co-Founder | — | — | — |
| 38 | Artin Bioscience Developer of therapeutics for respiratory diseases | $482K | 39 mo ago | — | Norbert Voelkel Co-Founder | — | — | — |
| 39 | Kalot Superfood Manufactures whole food ingredients based superfoods | $310K | 138 mo ago | — | Jessica Weiswasser Founder & CEO | — | — | — |
| 40 | Lumed Science Dental lighting | $297K | 143 mo ago | 5 | — | — | — | — |
| 41 | Strivision Provider of optical-based breathing diagnostic tools | $256K | 45 mo ago | — | Shane Transue Co-Founder & CEO | — | — | — |
| 42 | Lifeloc Breath alcohol and drug testing solutions for safety and compliance | $250K | 141 mo ago | 37 | — | Top 5M | 20 patents Point‑of‑care chemical/biological analysis and surface decontamination technologies | — |
| 43 | Sapphire Technology Manufacturer of patented dental equipments | $200K | 140 mo ago | — | Alan Wong Co-Founder | — | 7 patents Precision photometric measurement systems and dental photo‑curing equipment. | — |
| 44 | Ab Cuts Developing and marketing body fat reducing supplements | $200K | 162 mo ago | — | Matthew Hesse Founder & CEO | — | — | — |
| 45 | Ocutronics Develops retinal cameras for the diagnosis of ophthalmic diseases | $125K | 184 mo ago | 1 | Robert E. Levine Co-Founder | — | 11 patents Portable handheld retinal imaging devices for ophthalmic diagnostics | — |
Top 12 Life Sciences companies in Denver
#1
Series C · Denver, Colorado · founded 2018 · 26 employees$82Mraised▾
Developer of medical-grade wearable devices and data services for patient monitoring. it provides BioButton a rechargeable, multi-parameter wearable that captures vital signssuch as heart rate, respiratory rate, and skin temperature. It is integrated with data platforms BioCloud that provides advanced analytics and algorithmic notifications to support actionable triage and workflow efficiency and BioDashboard that Enables exception-based management for more proactive clinical decision-making.
- Dec 2025Series C$58.1M
- Jul 2021Series B$45M
- Aug 2020Series B$12M
- Dec 2018Series B$25M
#2
Series A · Denver, Colorado · founded 2017 · 15 employees$9.9Mraised▾
Provider of tools and instruments for research. The lead instrument, The Massbox, is the first Laser Ablation Laser Ionization Time of Flight Mass Spectrometer (LALI-TOF-MS) instrument on the market, capable of analyzing any sample, increasing the speed of development and discovery.
- Dec 2025Series A$120K
- Apr 2025Series A$1.1M
- Jul 2024Series A$1.5M
- May 2023Series A$6M
#3
Series A · Denver, Colorado · founded 2020 · 12 employees$35Mraised▾
Developer of endovascular robots. It offers solutions for doctors to conduct vascular interventions like placing stents in patients. The robots can be remotely operated.
- Oct 2025Series A$35M
#4
Seed · Denver, Colorado · founded 2011 · 6 employees$7.5Mraised▾
Point-of-care software for malnutrition assessment and improved patient care. This digital health company offers a clinical decision-support software and ultrasound analytics solution designed to establish a new standard of care for malnutrition. Their patented system automates the analysis of ultrasound images, providing accurate and actionable data to healthcare providers. This cloud-based software platform delivers immediate insights across various healthcare settings, supporting diagnosis, monitoring, and treatment. The technology aims to improve patient outcomes, enhance quality of life, and potentially reduce hospital stays and re-admission rates. It is a point-of-care test to assess malnutrition, enabling high fidelity documentation of malnutrition. The software is utilized by leading medical centers and able to provide a quantitative, non-invasive, rapid response assessment of muscle health.
- Nov 2025Seed$425K
- Apr 2025Seed$650K
- Jan 2025Seed$748.1K
- Aug 2023Seed$236K
#5
Series A · Denver, Colorado · founded 2011 · 10 employees$11.2Mraised▾
Developer of airway management system for ventilated patients. The company offers an integrated endotracheal tube stabilization system which includes "SolidAIRity Flex" that provides airway stability for ventilated patients
- Aug 2025Series A$5.6M
- Mar 2022Series A$1.9M
- Dec 2020Series A$150K
- Feb 2020Series A$3.1M
#6
Series D · Denver, Colorado · founded 2016 · 6 employees$4.4Mraised▾
Developing next-generation AEDs to improve survival rates from cardiac arrest. This medical device company is dedicated to changing how we respond to Sudden Cardiac Arrest (SCA) by creating compact, durable, and easy-to-use AEDs. The goal is to make life-saving technology accessible to everyone, ensuring individuals and communities can act confidently during emergencies. By focusing on intuitive and portable design, the company aims to improve survival rates and make a real difference in people's lives. They are committed to bringing AEDs to homes, workplaces, schools, and public spaces, partnering with communities to promote heart safety. The company is innovating in emergency response, defibrillator technology, and cardiac care, striving to make heart safety a priority globally.
- Jun 2025Series D$4M
- Jan 2024Series C$3.8M
- Aug 2023Series B$2.1M
- Jul 2019Series A—
#7
Seed · Denver, Colorado · founded 2020 · 9 employees$4.7Mraised▾
Cloud-based research data management tool for scientists. The company offers a laboratory data management and organization system. It comes with features like experiment data capture, data sharing, rather literature comparing, and bioinformatics analysis.
- Apr 2025Seed$3.6M
- May 2023Seed$3.7M
- Oct 2021Seed$1M
#8
Series E · Denver, Colorado · founded 2015 · 176 employees$499.5Mraised▾
Developer of gene editing technology for research. The product portfolio of the company includes developing a family of CRISPR enzymes (called MADzymes), bespoke nucleases for researchers and commercial partners, and a full suite of gene editing tools (software, instruments, and reagents) to increase the speed and efficiency of precision gene editing.
- Dec 2022Series E$27.8M
- Nov 2021Series E$1.9M
- Mar 2021Series E$150M
- Nov 2020Series D$58M
#9
Series A · Denver, Colorado · founded 2019 · 4 employees$4.9Mraised▾
Developer of therapeutics for auto-immune diseases. It offers HLA gene-editing platform that uses stem-cell-enriched blood to alter DNA to suppress the immune system to stop Rheumatoid arthritis's abnormal immune response.
- Jan 2025Series A$15M
- Apr 2024Series A$4.9M
- May 2023Seed$300K
- Oct 2022Seed$2M
#10
Seed · Denver, Colorado · founded 2019 · 2 employees$511Kraised▾
Developer of biosynthetic production platform for complex natural product compounds. It specializes in producing bio-identical natural product compounds for nutraceutical and pharmaceutical formulators. It utilizes a patented synthetic biology platform to optimize complex compound production via biosynthesis. The platform transforms microbes into efficient producers of key ingredients from simple sugars. It also provides process design services and production solutions to the synthetic biology industry.
- Apr 2025Seed$340K
- Nov 2022Seed$2.1M
#11
Funding Raised · Denver, Colorado · founded 1995 · 30 employees$956Kraised▾
Advanced microscopy systems and software solutions for biological research and analysis. The company designs and manufactures cutting-edge technologies for living cell, live cell, and intravital fluorescence microscopy. Their offerings include digital holography, spinning disk confocal, multi-photon, and lightsheet microscopy. The SlideBook microscopy software manages instrument control, image capture, processing, and data analysis, enabling scientists to focus on investigation. They provide advanced multi-dimensional microscopy platforms that are intuitive, modular, and meet the evolving needs of the biological research community. The company is committed to environmental responsibility and sustainability. Their products and services cater to the biotechnology and pharmaceutical industries, supporting research and development efforts. They offer solutions for various microscopy techniques, including light sheet, confocal, and multiphoton microscopy, along with software for image analysis and data management. The company's focus is on providing tools and technologies that advance scientific discovery and understanding in the life sciences.
- Jan 2025Grant (prize money)$505.3K
- Apr 2019Grant (prize money)$394.3K
- Sep 2015Grant (prize money)$56.5K
#12
Public · Denver, Colorado · founded 2012 · 51 employees$191.2Mraised▾
Developing transformative therapies for rare diseases, focusing on hyperinsulinism (HI). The company is a late-stage biopharmaceutical company dedicated to addressing serious unmet needs in rare diseases. It is focused on significantly improving outcomes for individuals with hypoglycemia caused by hyperinsulinism (HI). Their antibody therapy, ersodetug, is designed to treat all forms of HI and has shown substantial benefit in clinical trials and real-world use for the treatment of congenital hyperinsulinism (cHI) and tumor HI. The company is committed to developing medicines and working with partners to fight hyperinsulinism in all its forms. They are enrolling Phase III sunRIZE trial in the study of congenital hyperinsulinism. The company is focused on drug development for patients with rare diseases in multiple therapeutic areas.
- Oct 2020Post IPO$41M
- Jul 2019Post IPO$20M
- Apr 2018Post IPO$5M
- Feb 2018Post IPO$3.4M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Life Sciences coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
What Denver researches in biotechnology
- University of Colorado Denver17
- Metropolitan State University of Denver1
- University of Denver1
- Denver Health Medical Center1
Who's building biotechnology IP in Denver
- advanced energy2denver
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.