Best Life Sciences Companies in Sunnyvale, United States
The 123 best Life Sciences companies in Sunnyvale, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: 23andMe.
Our analysis of 164 Life Sciences companies
$34.7b in tracked funding; 83% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Life Sciences companies in Sunnyvale
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 23andMe 🦄 Provider of genetic test solutions to study ancestry, genealogy, and inherited traits | $861M | 31 mo ago | 755 755 → 549 (-27%) | Anne Wojcicki Co-Founder & CEO | WordPressApple iCloud MailGoogle Workspace+37 | Top 500k | 200 patents Consumer genomics: DNA testing, ancestry analysis, and secure genetic data processing. | — |
| 2 | Silk Road Medical Provider of neuroprotection devices for carotid artery disease | $189M | 107 mo ago | 352 | — | WordPressMySQLPHP+23 | Top 10M | 359 patents Percutaneous large‑bore vascular access, closure, and neuro‑protective sheath technologies | — |
| 3 | EBR Systems Revolutionizing cardiac rhythm management with leadless pacing technology for heart failure | $180M | 80 mo ago | 60 | Rick Riley Clinical Engineering Consultant / Co-founder | WebflowAmazon Web Servicescore-js+15 | Top 5M | 236 patents Patents concentrated in health & consumer products | 3 job openings |
| 4 | Aerin Medical Developer of therapeutic devices to improve nasal breathing | $144M | 18 mo ago | 66 66 → 156 (+136%) | Scott Wolf Co-Founder & CMO | WordPressApple iCloud MailMicrosoft 365+24 | Top 10M | 173 patents Therapies and devices for nasal/upper airway treatment and mucus reduction | 1 award |
| 5 | Xoft Electronic brachytherapy for multiple cancers | $117M | 188 mo ago | 5 | Michael Klein President and CEO | — | — | 106 patents Brachytherapy radiation delivery devices and attenuation methods for medical treatment | — |
| 6 | VytronUS Ablation system to treat cardiac arrhythmia | $115M | 117 mo ago | 32 | — | — | — | 137 patents Image-guided medical devices for tissue ablation and energy delivery | — |
| 7 | Spinal Kinetics Medical technology company providing innovative solutions for musculoskeletal pathologies and spinal care | $100M | 115 mo ago | 67 | — | — | — | 110 patents Implantable spinal stabilization, intervertebral disc and facet joint prosthetic devices. | — |
| 8 | Miramar Labs Microwave therapy for Axillary Hyperhydrosis | $94M | 119 mo ago | 34 | — | — | — | 113 patents Patents concentrated in health & consumer products | — |
| 9 | Sorbent Therapeutics Trusted Australian brand providing soft, strong, and sustainable tissue products | $91M | 145 mo ago | — | Don Joseph CEO | ShopifyYouTubeShop Pay+12 | Top 50M | — | — |
| 10 | Tact AI based customer engagement software for life science industries | $88M | 50 mo ago | 57 | — | — | — | 24 patents Targeted spinal delivery of biologic TNF inhibitors for brain injury therapy | — |
| 11 | Viveve Medical Developer of therapy devices for women’s intimate health | $84M | 43 mo ago | 47 | — | — | — | — | — |
| 12 | CardioMind Drug eluting stents for small coronary lesions | $75M | 218 mo ago | — | Charles Maroney CEO | — | — | 41 patents Patents concentrated in health & consumer products | — |
| 13 | aptus endosystems Aptus Endosystems is a medical tech company engaged in developing EVAR technologies for abdominal aortic… | $70M | 167 mo ago | 75 | — | — | — | 134 patents Endovascular surgical stapling and prosthesis delivery systems for minimally invasive organ repair | — |
| 14 | U-Systems Automated Ultrasound System for breast cancer screening | $64M | 167 mo ago | 41 | — | — | — | 1,296 patents High‑resolution hydrogel inks and multi‑plane stereolithography systems for 3D printing | — |
| 15 | Avantis Visualization technology for detection and prevention of GI cancers | $63M | 99 mo ago | 7 | — | — | — | — | — |
| 16 | Pharmacyclics Developing cancer and immune-mediated disease treatments to bring back the magic of normal | $56M | 166 mo ago | 607 | — | — | — | 1,612 patents BTK inhibitor drug compounds, crystalline forms, and pharmaceutical formulations for cancer therapy | — |
| 17 | Spiracur Wound healing device based on negative pressure therapy | $55M | 139 mo ago | 48 | — | — | — | 102 patents Patents concentrated in health & consumer products | — |
| 18 | RUBEDO LIFE SCIENCES Developer of therapeutics for age-related diseases | $52M | 25 mo ago | 23 23 → 31 (+35%) | Mark Gallop Co-Founder | — | — | — | — |
| 19 | BridGene Biosciences Developer of small-molecule drugs for the treatment of cancer 69Growth top 20%Patents top 23%Funding top 24%Innovation top 26% All 8 signals ▾Growthtop 20% Patentstop 23% Fundingtop 24% Innovationtop 26% Moattop 28% Talenttop 38% Globalbottom 40% Marketbottom 36% Growth: Headcount 15 → 25 (+67%) across vintages · Fresh capital in last 24 mo Patents: 44 patents matched (strict assignee match) · 35 filings since 2022 vs 9 in 2017-21 rank vs industry peers · Fliar Intelligence Index 69/100 | $50M | 8 mo ago | 25 25 → 31 (+24%) | Irene Yuan Co-Founder & Executive Vice President | — | — | 44 patents Small-molecule kinase and YAP/TAZ-TEAD inhibitors for targeted cancer therapy | — |
| 20 | Asthmatx SEO, web hosting, lighting, and hardware solutions for home and business | $50M | 229 mo ago | 40 | — | — | — | 196 patents Energy-based devices for targeted airway and lung therapy. | — |
| 21 | Paracor Medical Support mesh to aid in ventricular function | $44M | 227 mo ago | — | William Mavity ex-CEO | Cart FunctionalityWooCommerceWordPress+18 | Top 10M | — | — |
| 22 | Paracor Medical Developer of medical devices for the treatment of heart failure | $44M | 227 mo ago | — | William Mavity CEO | — | — | — | — |
| 23 | Pivot Medical Advancing sports medicine through innovative equipment, implants, and biologic solutions | $43M | 175 mo ago | 27 | Julian Nikolchev Founder & CEO | — | — | 191 patents Hip arthroscopy tools for labral repair, suture anchoring, and joint distraction | — |
| 24 | FlowCardia Medical technology company advancing global health through innovative solutions and services | $42M | 225 mo ago | — | Wick Goodspeed CEO | — | — | 206 patents Intravascular ultrasound catheters with enhanced distal tip design and steerability. | — |
| 25 | BioImagene Digital Pathology for clinical diagnostics and drug discovery | $40M | 212 mo ago | 40 | — | — | — | 12 patents Digital pathology imaging, slide scanning, and AI-driven medical image analysis | — |
| 26 | LabCyte Developer of accoustic liquid handling for the life science research | $33M | 113 mo ago | 184 | — | — | — | 236 patents Acoustic droplet ejection and ultrasonic microfluidic manipulation for high‑throughput assays | — |
| 27 | Amarantus Bioscience Therapeutics and diagnostics for neurodegenerative diseases. | $31M | 124 mo ago | 12 | Gerald Commissiong President & CEO | — | — | — | — |
| 28 | Intabio Analytical solutions for life science, diagnostics, and applied markets | $31M | 76 mo ago | 20 | Lena Wu Co-Founder | — | — | 98 patents Integrated microfluidic sample prep and isoelectric focusing for enhanced mass spectrometry analysis | — |
| 29 | Nanostim Wireless pacemaker | $30M | 157 mo ago | — | Drew Hoffmann President and CEO | — | — | 73 patents Patents concentrated in health & consumer products | — |
| 30 | Optra SCAN Digital pathology solutions for smarter, faster diagnostics and improved patient outcomes | $30M | 19 mo ago | 28 | Gauri Naik Co-Founder & Co-CEO | BootstrapApache HTTP ServerCloudflare+13 | Top 10M | — | 3 launchs |
| 31 | Oakbio Converting waste into biofuels using engineered microbes | $24M | 109 mo ago | 14 | Brian Sefton Founder & CEO & CTO | — | — | 45 patents Patents concentrated in health & consumer products | — |
| 32 | Proxim Diagnostics Developer of a handheld immunodiagnostic device for cardiac vascular diseases | $23M | 39 mo ago | 6 | — | — | — | — | — |
| 33 | Conformia Software Provider of product lifecycle management software for life sciences industries | $22M | 214 mo ago | 110 | — | — | — | 16 patents Software for managing and tracking formulation in pharmaceutical and beverage manufacturing | — |
| 34 | Tibion Corporation Bionic leg for restoration of mobility | $22M | 166 mo ago | — | Kevin Davidge CEO & CFO | — | — | 27 patents Powered exoskeletal joint actuation and orthotic devices for medical rehabilitation | — |
| 35 | Diagnostics for the Real World Provider of point-of-care diagnostic device for infectious disease detection | $20M | 81 mo ago | 8 | — | WordPressMySQLPHP+18 | Top 50M | — | — |
| 36 | Cepheid Developer of molecular diagnostic testing solutions | $19M | 58 mo ago | 1,299 | John Bishop Chairman & CEO | Cart FunctionalityAdobe Experience ManagerApple iCloud Mail+29 | Top 5M | 1,052 patents Automated molecular diagnostics: nucleic acid isolation, amplification, methylation/mutation profiling, and chip-based detection. | — |
| 37 | Intuitive Developer of robotic-assisted surgical systems | $17M | 324 mo ago | 6,262 6,262 → 13,035 (+108%) | Christopher Lozing Founder | DrupalApple iCloud MailMicrosoft 365+27 | Top 500k | 4 patents Patents concentrated in construction | — |
| 38 | Protera Platform developing protein-based on enzyme technology | $16M | 58 mo ago | 48 | — | Node.jsTailwind CSSReact+7 | Top 50M | — | — |
| 39 | Barrx Medical Ablation technology for Barrett's Esophagus treatment | $15M | 191 mo ago | 26 | — | — | — | — | — |
| 40 | Asimily Online platform for medical device asset management | $13M | 47 mo ago | 52 52 → 73 (+40%) | Hithesh Nama Chief Architect | WordPressApple iCloud MailGoogle Workspace+35 | Top 5M | 2 patents IoT device vulnerability assessment and remediation platform | 1 launch |
| 41 | InSilixa Developer of point-of-care diagnostics system based on semiconductor-based CMOS biochip technology | $13M | 139 mo ago | 40 | — | — | — | 44 patents Optical semiconductor biochips for multiplexed, time-gated nucleic acid detection | — |
| 42 | Angarus Developer of precision therapeutics to treat cancer | $11M | 66 mo ago | 2 | Lingyin Li Founder | — | — | — | — |
| 43 | Syntekabio AI-driven drug discovery and development, SaaS platform, supercomputing center | $11M | 26 mo ago | 52 | — | — | — | — | — |
| 44 | precise light surgical Precise Light Surgical was incorporated in 2008 and is based in Sunnyvale, California. | $9M | 72 mo ago | 4 | — | — | — | — | — |
| 45 | IMMvention Developer of anti-inflammatory therapies for neurodegenerative and cardiometabolic diseases | $9M | 41 mo ago | 10 | Jenny Ting Co-Founder | — | — | — | — |
| 46 | ClearLight Biotechnologies Provider of tissue processing and digital spatial image analysis platform | $9M | 90 mo ago | 2 | Karl Deisseroth Founder & Scientific Advisor | — | — | — | — |
| 47 | Loop Genomics Developer of DNA sequencing technologies | $8M | 91 mo ago | 7 | — | — | — | — | — |
| 48 | Neucyte Developer of tools for producing neural cells | $8M | 21 mo ago | 10 10 → 11 (+10%) | Tao Huang President and CEO | Wix eCommerceWixSentry+14 | Top 50M | — | — |
| 49 | PETcoil Provider of positron emission tomography for magnetic resonance imaging | $6M | 15 mo ago | 4 | — | — | — | — | — |
| 50 | Fluxus Provider of ultrasensitive bioanalysis systems and solutions | $5M | 13 mo ago | 20 | Peter Wagner Co-Founder & CEO | — | — | 43 patents Integrated optofluidic photonic sensors and waveguide fabrication for measurement and memory applications | — |
Top 12 Life Sciences companies in Sunnyvale
#1
Series B · Sunnyvale, California · founded 2018 · 25 employees$50.5Mraised▾
Developer of small-molecule drugs for the treatment of cancer. The company utilizes its proprietary Chemoproteomics platform, IMTAC that enables the screening of small molecules against all the proteins in live cells to discover drug candidates for high value and hard-to-drug targets that cause diseases.
- Oct 2025Series B$28M
- Jul 2022Series B$38.5M
- May 2021Series A$12M
- Sep 2020Grant (prize money)$298.9K
#2
Series E · Sunnyvale, California · founded 2011 · 66 employees$143.9Mraised▾
Developer of therapeutic devices to improve nasal breathing. It offers VivAer and RhinAer non‑invasive treatments that deliver tissue-sparing, temperature-controlled radiofrequency for nasal airway obstruction and chronic rhinitis.
- Dec 2024Series E$32.5M
- May 2022Series E$60M
- Aug 2020Series D$49.7M
- May 2019Conventional Debt$50M
#3
23andMe 🦄Acquired · Sunnyvale, California · founded 2006 · 755 employees$861Mraised▾
Provider of genetic test solutions to study ancestry, genealogy, and inherited traits. The platform provides a study regarding an individual's ancestry, genealogy, and inherited traits. The company also markets its data is categorized and searchable form to researchers and scientists.
- Nov 2023Post IPO$20M
- Dec 2020Series F$82.5M
- Jul 2018Series F$300M
- Aug 2017Series F$250M
#4
Series B · Sunnyvale, California · founded 2012 · 28 employees$30Mraised▾
Digital pathology solutions for smarter, faster diagnostics and improved patient outcomes. The company pioneers advanced digital slide scanners and AI-driven solutions, transforming pathology services. They empower healthcare institutions to transition to digital pathology, enhancing diagnostics, research, and education. Their technology offers high-speed imaging and analysis, streamlining lab workflows and improving patient outcomes. They provide whole slide scanners, AI-based analytics for automated abnormality detection, telepathology for remote consultations, and e-learning platforms for pathology education. Image management software ensures secure storage and analysis. Their solutions are cloud-based, HIPAA-compliant, and offer seamless integration. They provide flexible, scalable, and high-performance pathology solutions, improving diagnostic speed, accuracy, and collaboration.
- Nov 2024Series B$30M
#5
Funding Raised · Sunnyvale, California · founded 2016 · 20 employees$4.7Mraised▾
Provider of ultrasensitive bioanalysis systems and solutions. It develops and manufactures advanced technologies for the detection, diagnosis, monitoring, and treatment of disease. These technologies leverage expertise in photonics, engineering, chip fabrication, assay development, and reagent manufacturing. The company offers its solutions to researchers, clinicians, and industry partners. Its focus is on single-molecule counting and ultrasensitive biomolecular testing.
- Apr 2025Grant (prize money)$4.5M
- Sep 2021Grant (prize money)$230.3K
#6
Funding Raised · Sunnyvale, California · founded 2017 · 4 employees$5.7Mraised▾
Provider of positron emission tomography for magnetic resonance imaging. The company has developed a removable positron emission tomography (PET) insert that enables existing magnetic resonance imaging (MRI) scanners to cost-effectively achieve high-performance.
- Mar 2025Grant (prize money)$1.6M
- Apr 2020Grant (prize money)$4.1M
#7
Series A · Sunnyvale, California · founded 2015 · 10 employees$8Mraised▾
Developer of tools for producing neural cells. The company uses reprogramming technology to produce different neuronal subtypes in homogenous populations. Based on this technology the company's human neural invitro systems assess relevant higher-order electrophysiology readouts predicting drug efficacy and potential CNS Safety/Toxicology. The platform allows for the evaluation of human-specific neural phenotypes, not available in animal models.
- Sep 2024Grant (prize money)$500K
- May 2018Series A$6.7M
#8
Series A · Sunnyvale, California · founded 2018 · 23 employees$52Mraised▾
Developer of therapeutics for age-related diseases. The company uses propriety technology includes the ALEMBIC that focuses on developing medicines to combat biological aging by targeting pathologic cells like senescent ones that drive age-related diseases.
- Apr 2024Series A$40M
- Dec 2020Seed$12M
#9
Public · Sunnyvale, California · founded 2005 · 47 employees$84.4Mraised▾
Developer of therapy devices for women’s intimate health. The company develops Viveve System is a dual-energy platform device it incorporates cryogen-cooled monopolar radiofrequency technology (CMRF) to generate neocollagenesis for endovaginal procedures.
- Oct 2022Post IPO$14.7K
- Jun 2020Post IPO$341.2K
- Apr 2020Post IPO$3.1M
- May 2017Conventional Debt$30M
#10
Public · Sunnyvale, California · founded 2009 · 52 employees$11.1Mraised▾
AI-driven drug discovery and development, SaaS platform, supercomputing center, revolutionizing drug discovery with factory-level platforms and AI. They offer a comprehensive suite of services, including LaunchPad for diverse disease targets, and CLOUD-based SaaS solutions to streamline research. Their AI Bio-Supercom Center accelerates the generation and validation of drug candidates. They provide a disease-agnostic platform that continuously produces hits, leads, and drug candidates. Services include AI-driven hit screening, neoantigen prediction, antibody prediction, and biomarker analysis. They leverage supercomputing to support drug discovery and development projects, offering a one-stop service from hit screening to preclinical candidate materials. Their CLOUD-SaaS service automates drug development and genomics analysis, tailoring discoveries to customer needs.
- Apr 2024Post IPO$7.4M
- May 2018Series B$11.1M
#11
Series D · Sunnyvale, California · founded 2012 · 57 employees$88Mraised▾
AI-based customer engagement software for life science industries. The company has developed software that assists customer communication and management. It works through voice, SMS, and an offline mobile app for automating data entry, delivering insights, and increasing productivity. It allows members to reach customers, personalize each interaction, and capture insights. It also supports integration with CRM for a continuum of push and pulls engagement.
- Mar 2022Series D—
- Sep 2021Series D$33M
- Jan 2020Series C—
- Jun 2018Series C$27M
#12
Public · Sunnyvale, California · founded 2003 · 60 employees$179.7Mraised▾
Revolutionizing cardiac rhythm management with leadless pacing technology for heart failure. This company is dedicated to transforming the lives of patients suffering from heart failure. They develop technology that enables physicians to deliver optimal cardiac pacing. They focus on blending clinical insights with technological ingenuity to overcome the limitations of conventional cardiac resynchronization therapy (CRT). Their WiSE technology introduces a leadless, versatile, and physiologic approach to pacing the heart. They prioritize innovation, patient needs, and team growth. They are committed to advancing cardiac rhythm management through groundbreaking medical devices. They offer a breakthrough product, a team-oriented culture, and opportunities for career growth. They are a medical device company focused on cardiac care, offering a pioneering system set to redefine cardiac care.
- Oct 2019Series F$30M
- Nov 2017Series F$50M
- Jul 2014Series E$20M
- Jul 2014Series D$18.7M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Life Sciences coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Biotechnology is moving in the United States
A read on the academic research around Biotechnology — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 6,260 United States-affiliated papers.
- Harvard University209
- Cornell University177
- University of Tennessee at Chattanooga140
- Howard Hughes Medical Institute126
- Johns Hopkins University121
- Gene33→164
- Transcription (linguistics)11→79
- Antibody11→62
- Genome6→56
- Mutation7→56
- Gene8→110
- Cell culture3→62
- Gene expression3→62
- Fermentation2→54
- Downregulation and upregulation1→50
- Agriculture19→58
- Antibiotic resistance15→45
- Public health4→31
- Gene6→30
- Production (economics)5→29
Where biotechnology is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing biotechnology patents in the United States
United States biotechnology patent filing is accelerating — 457,918 filings from 8,000 assignees (2016–2025), led by Genentech, UNIV California, Regeneron Pharma; annual filings 36884→44446.
- Genentech18078
- UNIV California17948
- Regeneron Pharma16082
- Amgen10495
- Monsanto Technology9742
- UNIV Pennsylvania8521
- Harvard College7460
- UNIV Texas7378
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.