Best Life Sciences Companies in Los Angeles, United States
The 286 best Life Sciences companies in Los Angeles, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: ACELYRIN.
Our analysis of 164 Life Sciences companies
$34.7b in tracked funding; 83% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Life Sciences companies in Los Angeles
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|
| 1 | ACELYRIN Developer of drugs for immunology | $550M | 45 mo ago | 113 | 2020 | — | 20 patents Therapeutic antibodies targeting inflammatory pathways for autoimmune skin and joint diseases | — |
| 2 | TORL BioTherapeutics Developer of antibody-based therapeutics for the treatment of cancer 37Funding top 16%Moat top 31%Talent bottom 49%Market bottom 40% All 5 signals ▾Fundingtop 16% Moattop 31% Talentbottom 49% Marketbottom 40% Globalbottom 29% Funding: Raised $350M across 3 rounds · 3 rounds over 3 yrs (1.0/yr) Moat: Editorial + unicorn rating 8/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 37/100 | $350M | 8 mo ago | — | 2019 | Mark Attanasio Co-Founder | — | — |
| 3 | Kernel Developer of multimodal brain measurement technology for neuromedicine | $158M | 30 mo ago | 60 | 2016 | — | — | — |
| 4 | C3J Therapeutics Developing phage therapeutics to combat antibiotic-resistant bacterial infections | $124M | 114 mo ago | 60 | 2006 | — | — | — |
| 5 | Octant Provider of human cell interaction platform for drug discovery | $115M | 49 mo ago | 65 65 → 68 (+5%) | 2017 | — | 52 patents High-throughput bioassays, retinal gene‑therapy compounds, cell signaling analytics, pathogen diagnostics | 1 partnership |
| 6 | Science 37 Provider of a suite solution for clinical trials for researchers | $106M | 69 mo ago | 159 159 → 298 (+87%) | 2014 | — | 245 patents Specialty surfactants and polyether polymer ingredients for cosmetics and pharmaceutical formulations. | 1 job opening |
| 7 | Prolacta Bioscience Human milk-based nutrition for vulnerable infants, improving health outcomes | $99M | 97 mo ago | 314 | 1999 | — | 231 patents Human milk-derived nutritional products and processing technologies for infant and clinical nutrition | 1 launch |
| 8 | Kite Pharma Developer of cancer immunotherapy products using genetic engineering | $98M | 98 mo ago | 17 | 2009 | — | 1,184 patents Engineering CAR‑T cells and immune‑cell vectors for targeted cancer immunotherapy | — |
| 9 | Auspex Pharmaceuticals Developer of small molecule therapeutics for neurodegenerative diseases | $92M | 149 mo ago | 37 | 2001 | — | 952 patents Osmotic drug delivery and VMAT2‑targeted therapies for movement disorder treatment | — |
| 10 | Capricor Therapeutics Developer of regenerative medicine for cardiovascular disorders | $84M | 78 mo ago | 55 | 2005 | — | — | — |
| 11 | Armata Pharmaceuticals Developer of phage therapeutics | $73M | 50 mo ago | 69 69 → 74 (+7%) | 1989 | Deborah Birx CEO | — | — |
| 12 | Bionaut Labs Developer of miniature robots for drug delivery | $63M | 42 mo ago | 50 | 2015 | Alex Shpunt Co-Founder | 76 patents Patents concentrated in health & consumer products | — |
| 13 | Puma Biotechnology Developer of tyrosine kinase inhibitor for the treatment of breast cancer | $60M | 51 mo ago | 193 193 → 258 (+34%) | 2010 | — | — | — |
| 14 | ImaginAb Immune imaging technology for cancer and autoimmune disease management | $60M | 60 mo ago | 17 17 → 12 (-29%) | 2007 | — | 131 patents Therapeutic antibodies targeting CD8, DLL3, and integrin αvβ6 for cancer immunotherapy | — |
| 15 | Health-Ade Bubbly probiotic tea and gut-healthy soda for a happier gut | $54M | 66 mo ago | 135 135 → 152 (+13%) | 2012 | Vanessa Dew Co-Founder | — | 2 launchs |
| 16 | Appia Bio Developer of cell therapies | $52M | 61 mo ago | 39 | 2020 | JeenJoo Kang CEO | — | — |
| 17 | MannKind Corp Developer of small-molecule drugs | $50M | 63 mo ago | 322 | 1991 | Michael Castagna Chief Executive Officer | 1,985 patents Dry powder inhaler devices and pulmonary drug formulation/composition technologies. | 1 internship · 1 award |
| 18 | Pictor Labs AI-based solutions for pathological image analysis | $49M | 17 mo ago | 29 | 2019 | Yair Rivenson Co-Founder & CEO | 6 patents AI-powered digital pathology: virtual staining, immunostain analysis, and analyte detection. | — |
| 19 | Second Sight Provider of an implantable visual prosthetic for blind individuals | $37M | 47 mo ago | 14 | 2000 | Adam Mendelsohn CEO | 802 patents AI-driven cyber risk analytics and implantable brain-computer interface neurotechnology solutions. | — |
| 20 | Trethera Developer of small molecule cancer therapeutics that target DNA replication and integrity 29Funding top 30%Patents top 37%Moat top 37%Product top 41% All 9 signals ▾Fundingtop 30% Patentstop 37% Moattop 37% Producttop 41% Innovationtop 42% Techtop 47% Talentbottom 49% Globalbottom 33% Marketbottom 18% Funding: Raised $31.0M across 20 rounds · 20 rounds over 11 yrs (1.8/yr) Patents: 15 patents matched (strict assignee match) · 15 filings since 2022 vs 0 in 2017-21 rank vs industry peers · Fliar Intelligence Index 29/100 | $31M | 8 mo ago | 3 | 2013 | Ken Schultz Chairman & CEO | 15 patents Patents concentrated in health & consumer products | — |
| 21 | Pelage Pharmaceuticals Developer of therapeutics for hair loss treatment in men and women | $31M | 9 mo ago | — | 2018 | William Lowry Co-Founder & President | — | — |
| 22 | Aadi Bioscience Precision medicine company improving lives with mTOR-driven disease therapies | $23M | 15 mo ago | 95 | 2008 | Neil Desai CEO & Chairman | — | — |
| 23 | Needed Provider of nutritional supplements for prenatal care | $23M | 33 mo ago | 54 | 2017 | Julie Sawaya Co-Founder and Co-CEO | — | — |
| 24 | Aneuvo Developer of a medical device for the treatment of spinal cord injuries 32Growth top 35%Funding top 39%Tech top 49%Talent bottom 49% All 6 signals ▾Growthtop 35% Fundingtop 39% Techtop 49% Talentbottom 49% Marketbottom 25% Globalbottom 25% Growth: Fresh capital in last 24 mo Funding: Raised $22.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 32/100 | $22M | 3 mo ago | — | 2016 | Yi Lo CEO | — | — |
| 25 | NeOnc Technologies Developer of drug delivery methods for pharma-based therapeutics | $19M | 10 mo ago | 4 | 2008 | — | 48 patents Monoterpene-derived anticancer drug formulations, especially perillyl alcohol derivatives. | — |
| 26 | Sensydia Cardio-respiratory monitoring device 27Funding top 36%Product top 36%Moat top 38%Innovation top 44% All 10 signals ▾Fundingtop 36% Producttop 36% Moattop 38% Innovationtop 44% Talentbottom 49% Patentsbottom 48% Techbottom 44% Globalbottom 33% Marketbottom 22% Newsbottom 22% Funding: Raised $17.8M across 7 rounds · 7 rounds over 10 yrs (0.7/yr) Product: 6 distinct product lines · Company stage: Series A rank vs industry peers · Fliar Intelligence Index 27/100 | $18M | 14 mo ago | 8 | 2015 | Anthony Arnold President & Chief Executive Officer | 4 patents Non‑invasive cardiac acoustic analysis and multi‑sensor pulmonary pressure monitoring devices | — |
| 27 | MAX BioPharma Biopharmaceutical company pioneering Oxysterol Therapeutics® for debilitating and fatal human diseases | $10M | 15 mo ago | 5 | 2010 | Farhad Parhami D President & CEO | — | — |
| 28 | Partillion Developer of single-cell assays for cell analysis | $10M | 14 mo ago | 6 | 2020 | — | — | 2 launchs |
| 29 | Immix Biopharma Developer of therapeutics for amyloidosis, autoimmune diseases, and oncology indications 53Product top 14%News top 24%Growth top 32%Funding top 34% All 12 signals ▾Producttop 14% Newstop 24% Growthtop 32% Fundingtop 34% Innovationtop 39% Patentstop 41% Moattop 45% Techtop 47% Fin. healthtop 49% Talentbottom 49% Marketbottom 38% Globalbottom 36% Product: 5 distinct product lines · Company stage: Public News: 5 BI events in 12 mo (of 16 tracked, 7 types) · +150% YoY rank vs industry peers · Fliar Intelligence Index 53/100 | $9M | 9 mo ago | 11 | 2012 | Ilya Rachman Co-Founder & CEO | 25 patents Targeted nanoparticle delivery of therapeutic agents for cancer and inflammatory diseases | — |
| 30 | Illuminant Developer of a surgical navigation system using augmented reality technology | $9M | 1 mo ago | 9 | 2021 | — | — | — |
| 31 | Supergut Internet-first brand offering multi-category nutritious products | $8M | 15 mo ago | 30 | 2019 | Marc Washington Founder & CEO | — | — |
| 32 | StrokeDx Developer of a portable device for the diagnosis of stroke | $7M | 24 mo ago | 3 | 2021 | Alexander Ballatori Co-Founder & CEO | 14 patents Noninvasive brain monitoring sensors and coil positioning systems for handheld diagnostics. | — |
| 33 | SpineX Developer of a medical device for neurological conditions | $6M | 9 mo ago | 15 | 2018 | — | 5 patents Non‑invasive wearable CNS neuromodulation devices for spinal pain and motor disorder therapy | — |
| 34 | Sanguine Building a databank of patient-derived data for advanced research | $6M | 31 mo ago | 73 73 → 100 (+37%) | 2010 | Brian Neman Co-Founder & CEO | 3 patents Integration of negative pressure wound therapy with ostomy faceplate devices | 6 job openings · 1 launch |
| 35 | Essenvia Provider of regulatory information management (RIM) platform for the MedTech industry | $5M | 31 mo ago | 19 | 2018 | Soumya Mahapatra Founder & CEO | 3 patents Patents concentrated in computing, sensing & instrumentation | — |
| 36 | Rarity PBC Developer of gene therapies for rare genetic diseases | $5M | 7 mo ago | — | 2023 | Donald Kohn Co-Founder | — | — |
| 37 | LighthouseAI Provider of software and services for pharmaceutical state licensing and compliance 40Growth top 35%Tech top 39%Funding top 45%Talent bottom 49% All 7 signals ▾Growthtop 35% Techtop 39% Fundingtop 45% Talentbottom 49% Globalbottom 36% Marketbottom 27% Newsbottom 22% Growth: Fresh capital in last 24 mo Tech: 39 technologies across 5/8 capability areas · Cloud: Amazon Cloudfront, Amazon Web Services rank vs industry peers · Fliar Intelligence Index 40/100 | $5M | 1 mo ago | 18 | 2023 | Sumeet Singh Founder & CEO | — | — |
| 38 | Kairos Pharma Developer of T-cell therapies against cancer and drug resistance | $4M | 17 mo ago | 3 | 2016 | — | — | — |
| 39 | MyoGene Bio Manufacturer of devices for muscular dystrophy treatment 8Talent top 38%Funding top 45%Global bottom 29%Market bottom 10% All 4 signals ▾Talenttop 38% Fundingtop 45% Globalbottom 29% Marketbottom 10% Talent: 2 named leaders on record · 2 C-suite/founder profiles curated Funding: Raised $3.2M across 6 rounds · 6 rounds over 5 yrs (1.2/yr) rank vs industry peers · Fliar Intelligence Index 8/100 | $3M | 7 mo ago | 3 | 2020 | April Pyle Co-Founder | — | — |
| 40 | Symphony Biosciences Developer of drugs to treat solid tumors | $2M | 16 mo ago | 4 | 2021 | Manish Butte Co-Founder | — | — |
| 41 | Molecular Instruments Provider and developer of molecular instruments for drug development | $2M | 21 mo ago | 28 | 2018 | — | — | 2 launchs |
| 42 | SeqOnce Biosciences Provider of products & services for DNA and RNA Next Generation Sequencing sample preparation | $2M | 20 mo ago | 17 | 2014 | — | — | — |
| 43 | AesculaTech AesculaTech is a biomedical startup that uses custom chemistry and smart materials to develop adaptable and… | $2M | 14 mo ago | 2 | 2016 | Niki Bayat Co-Founder & CEO | 14 patents Advanced polymer-based drug delivery systems and injectable biomedical devices | — |
| 44 | Bexa Provider of a device for breast examination in women | $2M | 18 mo ago | — | 1997 | Joe Peterson CEO | — | — |
| 45 | The Plug Developer of plant-based hangover drinks | $2M | 8 mo ago | 40 | 2019 | — | 3 patents Advanced power management systems for electronic devices | — |
| 46 | Kannalife Provider of cannabis-based therapeutic agents for inflammation | $2M | 23 mo ago | 6 | 2010 | — | 8 patents Therapeutic functionalized 1,3‑benzene diol compounds for treating hepatic encephalopathy | — |
| 47 | Metanoia Bio Provider of platform technology to prevent diabetes | $1M | 3 mo ago | 5 | 2020 | Jake Mendelsohn Co-Founder | — | — |
| 48 | Lucendi AI-enabled smart measurement systems using computational microscopy technology for micro-object… | $1M | 7 mo ago | 5 | 2016 | Aydogan Ozcan Co-Founder | — | — |
| 49 | Voxel Healthcare Provider of clinical decision support tools for pediatric radiology | $944K | 23 mo ago | — | 2017 | Sinchai Tsao CEO | — | — |
| 50 | Hura Imaging AI-powered medical imaging software solutions improving safety, efficiency, and diagnostic quality | $250K | 16 mo ago | — | 2015 | Danny JJ Wang Founder | — | — |
Top 12 Life Sciences companies in Los Angeles
#1
Series C · Los Angeles, California · founded 2019$350Mraised▾
Developer of antibody-based therapeutics for the treatment of cancer. The company's lead candidate, TORL-1-23, is a CLDN6-directed antibody-drug conjugate for patients across multiple cancer types. Also, it is developing a broad pipeline of novel preclinical ADCs and mAb in oncologic indications.
- Oct 2025Series C$96M
- Apr 2024Series B$158.3M
- Apr 2023Series B$158M
#2
Series C · Los Angeles, California · founded 2016$22Mraised▾
Developer of a medical device for the treatment of spinal cord injuries. The company focuses on the development of medical devices and systems to modulate the central, peripheral, autonomous, and enteric nervous systems for the treatment of spinal cord injury, multiple sclerosis, and gastrointestinal tract diseases. ExaStim is a non-invasive neuromodulation system to restore lost function.
- Mar 2026Series C$22M
#3
Seed · Los Angeles, California · founded 2021 · 9 employees$9Mraised▾
Developer of a surgical navigation system using augmented reality technology. The system projects anatomical information directly onto the patient, eliminating the need to shift attention between screens. It simplifies surgical workflow with non-invasive setup, reducing complexity and time. The technology is applicable to various care settings and specialties.
- Apr 2026Seed$8.4M
- Sep 2024Grant (prize money)$295K
- Jan 2024Grant (prize money)$274.9K
#4
Series C · Los Angeles, California · founded 2013 · 3 employees$31Mraised▾
Developer of small molecule cancer therapeutics that target DNA replication and integrity. Its lead compounds target metabolic pathways that control DNA replication and signal transduction pathways that allow cells to repair DNA damage. Its lead candidate is a deoxycytidine kinase inhibitor that is currently under investigation for leukemia and solid tumors.
- Sep 2025Grant (prize money)$1.8M
- Sep 2025Grant (prize money)$610.9K
- Aug 2025Grant (prize money)$2M
- Aug 2025Grant (prize money)$995K
#5
Series A · Los Angeles, California · founded 2023 · 18 employees$4.6Mraised▾
Provider of software and services for pharmaceutical state licensing and compliance. The company offers software solutions for compliance requirement research and maintenance. It also provides services such as regulatory filings, accreditation support, inspection preparation, and policy development. The company serves pharmaceutical manufacturers, wholesale distributors, logistics companies, and pharmacies.
- Apr 2026Series A$8M
- Aug 2023Seed$4.6M
#6
Series B · Los Angeles, California · founded 2018$30.8Mraised▾
Developer of therapeutics for hair loss treatment in men and women. It provides a topical, non-invasive small molecule pharmacological platform that can be used to activate hair follicle stem cells and promote thick hair growth.
- Sep 2025Series B$120M
- Aug 2024Series A$14M
- Feb 2024Series A$16.8M
#7
Public · Los Angeles, California · founded 2008 · 4 employees$18.7Mraised▾
Developer of drug delivery methods for pharma-based therapeutics. The company develops intranasal inhalation of perillyl alcohol for the treatment of malignant brain cancer (gliomas). The company has secured worldwide rights to NEO100, a purified version of perillyl alcohol, and has obtained approval from the FDA to perform clinical trials in patients with recurrent Grade 4 glioma.
- Aug 2025Grant (prize money)$2.5M
- Jul 2024Series A$18.3M
- Feb 2022Seed$50K
- Feb 2013Seed$24.8K
#8
Series B · Los Angeles, California · founded 2019 · 29 employees$48.8Mraised▾
AI-based solutions for pathological image analysis. It provides an AI-based tool to lab team members to analyze the tissue images responsible for causing infections, cancer, and other diseases.
- Jan 2025Series B—
- Aug 2024Series B$30M
- May 2022Series A$15.2M
- Aug 2020Seed$3.6M
#9
Public · Los Angeles, California · founded 2012 · 11 employees$9.1Mraised▾
Developer of therapeutics for amyloidosis, autoimmune diseases, and oncology indications. The company's product line include NXC-201, a BCMA-targeting CAR-T therapy for relapsed/refractory AL amyloidosis, multiple myeloma, and autoimmune disease and IMX-110 for solid tumors like soft tissue sarcoma.
- Sep 2025Post IPO$9.1M
- Aug 2017Series A—
#10
Seed · Los Angeles, California · founded 2020 · 3 employees$3.2Mraised▾
Manufacturer of devices for muscular dystrophy treatment
- Nov 2025Seed$400K
- May 2025Grant (prize money)$1.3M
- Sep 2024Grant (prize money)$110K
- May 2023Seed—
#11
Series A · Los Angeles, California · founded 2015 · 8 employees$17.8Mraised▾
Cardio-respiratory monitoring device. It develops a wireless, non-invasive Cardio-Respiratory monitoring device that will help patients measure real-time heart function. The company is operating in stealth mode.
- Apr 2025Grant (prize money)$2.2M
- Jun 2023Grant (prize money)$3M
- May 2023Series A$8M
- May 2023Grant (prize money)$605.5K
#12
Seed · Los Angeles, California · founded 2020 · 5 employees$1.2Mraised▾
Provider of platform technology to prevent diabetes. It offers a conserved pathway for physiologically induced tissue regeneration that will restore beta-cell function and induce homeostatic cell fitness competition for the maintenance of functional beta-cell mass.
- Mar 2026Seed$900K
- Jul 2024Grant (prize money)$295.3K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Life Sciences coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Biotechnology is moving in the United States
A read on the academic research around Biotechnology — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 6,260 United States-affiliated papers.
- Harvard University209
- Cornell University177
- University of Tennessee at Chattanooga140
- Howard Hughes Medical Institute126
- Johns Hopkins University121
- Gene33→164
- Transcription (linguistics)11→79
- Antibody11→62
- Genome6→56
- Mutation7→56
- Gene8→110
- Cell culture3→62
- Gene expression3→62
- Fermentation2→54
- Downregulation and upregulation1→50
- Agriculture19→58
- Antibiotic resistance15→45
- Public health4→31
- Gene6→30
- Production (economics)5→29
Where biotechnology is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing biotechnology patents in the United States
United States biotechnology patent filing is accelerating — 457,918 filings from 8,000 assignees (2016–2025), led by Genentech, UNIV California, Regeneron Pharma; annual filings 36884→44446.
- Genentech18103
- UNIV California17969
- Regeneron Pharma16083
- Amgen10510
- Monsanto Technology9754
- UNIV Pennsylvania8526
- Harvard College7463
- UNIV Texas7382