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Radar · Life Sciences in Palo Alto

Best Life Sciences Companies in Palo Alto, United States

The 165 best Life Sciences companies in Palo Alto, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Medable.

165companies tracked
$4.7Bdisclosed funding
1unicorns
97have raised
FLIAR INTELLIGENCE · LIFE SCIENCES × PALO ALTO

Our analysis of 164 Life Sciences companies

$34.7b in tracked funding; 83% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.

164companies analysed
83%cloud-native stacks
2025funding peak (by rounds)
7unicorns
2016median founding year
383kcombined LinkedIn audience
61%of audience held by top 3
2companies hiring publicly (12 mo)

Ranked: Best Life Sciences companies in Palo Alto

#CompanyDisclosed fundingLast roundEmployeesFoundedFounderPatents & IP focusRecent signals
1Medable 🦄
Provider of a cloud based clinical trail management tool for researchers
$521M56 mo ago376
376 → 359 (-5%)
2012James Sas
Co-Founder
14 patents
Digital health data integration, remote patient monitoring, and clinical trial management platforms
—
2BridgeBio
Developer of therapeutics for the treatment of genetic diseases
$434M25 mo ago3832015Neil Kumar
Co-Founder & CEO
32 patents
Targeted small‑molecule cancer combos (KRAS, EGFR, SHP2) and metabolic kidney disease therapies
1 award
3CardioDx
Precision medicine: blood tests for coronary artery disease assessment
$282M113 mo ago992004—45 patents
Molecular diagnostic biomarkers and computational scoring for coronary artery disease and smoking status
—
4Pelikan Technologies
Top kimono buying sites comparison, reviews, and rankings
$183M208 mo ago—2001Dirk Boecker
CEO
232 patents
Point‑of‑care blood sampling and micro‑injection devices for minimally invasive diagnostics
—
5TrueBinding
Developer of biotherapeutic solutions for cancer treatment
$170M44 mo ago892015—80 patents
Therapeutic antibodies targeting Galectin‑3 and protein‑aggregation inhibition for disease treatment
—
6OrsoBio
Developer of therapeutics for multiple metabolic diseases
$152M15 mo ago102021—45 patents
Small-molecule LXR modulators and ACMSD inhibitors for dyslipidemia and metabolic disease therapy
—
7Forty Seven
Developer of therapies for the treatment of a wide range of diseases
$150M82 mo ago7,1282015—248 patents
Bispecific antibody therapeutics targeting CD47/CD20 for hematologic cancers.
—
8Bitterroot Bio
Immunotherapy to develop and deliver medicines for cardiovascular disease
$145M36 mo ago12
12 → 29 (+142%)
2021Irving Weissman
Co-Founder
——
9Exai Bio
Developer of RNA biomarkers and AI platform for cancer detection
$138M21 mo ago472018Babak Alipanahi
Co-Founder & Chief Scientific Officer
—1 job opening · 1 launch · 1 partnership
10Immune-Onc Therapeutics
Developer of antibodies to target immune system and tumor microenvironment
$138M41 mo ago24
24 → 12 (-50%)
2016———
11Affymax
Drug for treatment of chronic kidney disease
$131M207 mo ago722001—162 patents
Erythropoietin receptor agonist peptides and PEGylated peptide drug delivery technologies
—
12Inceptive
AI-based RNA molecular modeling tool for the vaccine
$120M33 mo ago352021Jakob Uszkoreit
Co-Founder & CEO
—1 partnership
13Pheast
Developer of immunotherapeutics for cancer treatment
$101M43 mo ago202020Roy Maute
Co-Founder
—1 launch · 1 award
14Antheia
Genetically engineered yeast cells to produce medicinal products
64Funding top 20%Patents top 25%Moat top 28%Innovation top 34%
All 12 signals ▾
Fundingtop 20%
Patentstop 25%
Moattop 28%
Innovationtop 34%
Producttop 35%
Growthtop 36%
Talenttop 40%
Techtop 45%
Newstop 45%
Partnerstop 45%
Globalbottom 47%
Marketbottom 45%
Funding: Raised $96.4M across 13 rounds · 13 rounds over 11 yrs (1.2/yr)
Patents: 82 patents matched (strict assignee match) · 52 filings since 2022 vs 30 in 2017-21
rank vs industry peers · Fliar Intelligence Index 64/100
$96M4 mo ago50
50 → 66 (+32%)
2013Christina Smolke
Co-Founder & CEO
82 patents
Biotechnological production and optimization of opioid alkaloids (benzylisoquinoline and morphinan)
2 job openings
15Anacor Pharmaceuticals
Developer of small-molecule therapeutics for the treatment of infectious and autoimmune diseases
$90M122 mo ago1102002—769 patents
Oxaborole-based anti-inflammatory and antiparasitic drug compounds and formulations
—
16Centrillion Technologies
Developer of DNA chips and molecular assays
$87M95 mo ago232009—6 patents
High-throughput DNA sequencing reagents, microarray fabrication, and surface-modified platforms
—
17InCarda Therapeutics
Developer of therapeutic solutions for acute cardiovascular symptoms
$80M67 mo ago302009Narsi Rangachari
Co-Founder
——
18Science Exchange
Online marketplace for outsourcing scientific research
$78M80 mo ago392011Dan Knox
Co-Founder & COO
——
19Excellergy
Developer of trifunctional effector cell response inhibitors for allergic diseases
$70M8 mo ago—2020Theodore Jardetzky
Co-Founder
5 patents
Therapeutic antibodies and fragments that bind IgE for allergy treatment
—
20Comprehend
Provider of cloud-based software for clinical operations teams
$66M87 mo ago22010———
21Polares Medical
Developer of medical devices for treating mitral valve regurgitation
$65M3 mo ago202010Jacques Essinger
Founder & CEO
——
22Eidos Therapeutics
Developer of a small-molecule treatment solution for transthyretin amyloidosis
$64M98 mo ago702016Isabella Graef
Co-Founder
——
23Satiety
Device for transoral gastroplasty, an endoscopic approach to satiety induction
$64M200 mo ago102000—80 patents
Minimally invasive gastric volume-reduction and partitioning devices for obesity therapy.
—
24Onera
Developer of a wearable sleep monitoring system
$60M29 mo ago502018Pieter Ermers
VP Research and Development & Founder
—1 partnership
25Ancora Biotech
Developer of Immunotherapeutics for B cell cancers, metabolic diseases, and chronic hepatitis B infections
$60M48 mo ago122021Ben Buelow
CEO
——
26Zenflow
Developer of device to treat urinary obstruction related to BPH
$55M19 mo ago25
25 → 42 (+68%)
2014Shreya Mehta
ex-Co-Founder & CEO
69 patents
Precise implantation and imaging devices for prostatic urethra treatments
—
27Endpoint Health
Developer of precision therapeutics for immune-mediated diseases
$52M48 mo ago212018Jason Springs
Co-Founder &CEO
——
28Vibrynt
Vibrynt: Stylish coat hooks and home storage solutions provider
$50M168 mo ago—2006Beverly Huss
President and CEO
61 patents
Minimally invasive gastric volume reduction devices for obesity treatment.
—
29Kalaris Therapeutics
Developer of therapeutics for retinal disorders
$50M6 mo ago—2024Srinivas Akkaraju
Co-Founder & Director
——
30Vincerx Pharma
Developer of cancer therapeutics
$50M57 mo ago432020———
31Signostics
Provider of POC ultrasound device to calculate bladder volume
$44M127 mo ago1122005Stewart Bartlett
Co-Founder & COO
——
32Neuraltus
Developing proprietary small molecule immunomodulator drugs for neurodegenerative diseases
$43M120 mo ago52009———
33Carbylan
Therapeutics using polymers of hyaluronic acid for pain management.
$43M135 mo ago72004———
34Cellanome
Developer of the omic data platform for researchers
$43M39 mo ago—2020Mostafa Ronaghi
Co-Founder
77 patents
Microfluidic platforms for cellular analysis, imaging, sorting, and multiplex assay screening
—
35Neumentum
Developing non-opioid pain management solutions for acute and chronic pain
$41M37 mo ago82017Joseph Pergolizzi
Co-Founder
5 patents
Topical analgesic and anti-inflammatory pharmaceutical formulations
—
36Overture Life
Developer of embryology diagnosis device for professionals
67Patents top 26%AI top 28%Talent top 28%Funding top 29%
All 11 signals ▾
Patentstop 26%
AItop 28%
Talenttop 28%
Fundingtop 29%
Moattop 31%
Innovationtop 32%
Growthtop 35%
Techbottom 44%
Globalbottom 43%
Marketbottom 37%
Newsbottom 18%
Patents: 44 patents matched (strict assignee match) · 34 filings since 2022 vs 10 in 2017-21
AI: Holds AI/ML patents (G06N-family CPC) · Product described with: ai powered
rank vs industry peers · Fliar Intelligence Index 67/100
$37M7 mo ago412017Jose Horcajadas
Co-Founder & Chief Scientific Officer
44 patents
Automated microinjection and microfluidic handling for IVF and embryo selection
1 launch · 1 partnership
37N Focus Neuro
Endovascular neurosurgery solutions for the treatment of intracranial aneurysms
$37M144 mo ago62007———
38Kodiak Sciences
Developer of therapeutics to treat retinal diseases
$36M97 mo ago112
112 → 138 (+23%)
2009Victor Perlroth
Chairman and CEO
211 patents
Antibody‑drug conjugates and protein therapeutics targeting cytokines and ocular disease.
—
39OmniAb
Therapeutic antibody discovery company providing diverse antibody repertoires and cutting-edge screening…
48Patents top 25%Innovation top 33%Funding top 36%Tech top 42%
All 10 signals ▾
Patentstop 25%
Innovationtop 33%
Fundingtop 36%
Techtop 42%
Markettop 46%
Moattop 48%
Globalbottom 38%
Fin. healthbottom 38%
Growthbottom 33%
Newsbottom 18%
Patents: 30 patents matched (strict assignee match) · 29 filings since 2022 vs 1 in 2017-21
Innovation: 30 patents (top 42% of patent-holders) · 29 filings since 2022 vs 1 in 2017-21
rank vs industry peers · Fliar Intelligence Index 48/100
$30M9 mo ago952012—30 patents
Therapeutic antibodies for immune checkpoints and viral targets, plus APOL1 small‑molecule inhibitors.
—
40Mekonos
Developer of silicon-based nanomachine chips
$30M55 mo ago482016Greg Sitters
Co-Founder
49 patents
Patents concentrated in transport & manufacturing processes
—
41Epalex
Developer of therapies for treating neurological disorders
$26M7 mo ago22009Brendan Magrab
CEO
30 patents
Prodrug and formulation technologies for intravenous anesthetic propofol delivery
—
42Artificial Intelligence
AI‑driven lab automation platform
$22M61 mo ago26
26 → 15 (-42%)
2018David Fuller
Chief Executive Officer
97 patents
Patents concentrated in computing, sensing & instrumentation
—
43Pumpkinseed
Developer of protein sequencing technology using silicon photonics and machine learning
67Talent top 35%Funding top 36%AI top 45%Global bottom 33%
All 4 signals ▾
Talenttop 35%
Fundingtop 36%
AItop 45%
Globalbottom 33%
Talent: 3 named leaders on record
Funding: Raised $20.3M across 2 rounds · 2 rounds over 1 yrs (2.0/yr)
rank vs industry peers · Fliar Intelligence Index 67/100
$20M1 mo ago—2021Jennifer Dionne
Co-Founder
——
44GEn1E
Developer of therapeutics for the treatment of inflammatory and rare diseases
$17M7 mo ago192018Ritu Lal
Co-Founder & CEO
——
45Surf Bio
Developer of therapeutics for the treatment of multiple diseases
$16M25 mo ago42021Jennifer Schneider Md
Founder
——
46HUMA.AI
AI-based business development tool for healthcare
$14M14 mo ago282018Lana Feng
Co-Founder & CEO
—1 launch
47Electron Optica
Provider of solutions for electron microscopy and electron lithography
37Funding top 44%Talent bottom 45%Global bottom 29%
All 3 signals ▾
Fundingtop 44%
Talentbottom 45%
Globalbottom 29%
Funding: Raised $9.3M across 8 rounds · 8 rounds over 15 yrs (0.5/yr)
Talent: 1 named leader on record
rank vs industry peers · Fliar Intelligence Index 37/100
$9M14 mo ago—2011Marian Mankos
Founder & CEO
——
48PhnyX Lab
AI-powered solutions to simplify workflows in pharmaceutical research
$4M10 mo ago—2024Harshit Gupta
Co-Founder
——
49Interface Biosciences
Developer of microbiome therapeutics to treat inflammatory diseases
$3M30 mo ago72020———
50Greenstone
AI-based computational platform for drug discovery
$3M24 mo ago132021Joseph Wu
Co-Founder
—2 partnerships

Top 12 Life Sciences companies in Palo Alto

#1
Series C · Palo Alto, California · founded 2013 · 50 employees
$96.4Mraised
▾

Antheia is focused on developing medicines using its technology. Its technology combines synthetic biology, informatics, and fermentation technology to provide plant-based medicines. It is currently working on engineering the yeast cells genetically to produce natural medicinal products.

Fliar Intelligence Index™ 64how this company ranks against its industry peers
Funding
top 20%
Patents
top 25%
Moat
top 28%
Innovation
top 34%
Product
top 35%
Growth
top 36%
Funding: Raised $96.4M across 13 rounds · 13 rounds over 11 yrs (1.2/yr) · Last round Series C (Jan 2026)
Patents: 82 patents matched (strict assignee match) · 52 filings since 2022 vs 30 in 2017-21 · Latest publication 2025
Moat: Editorial + unicorn rating 8/10 · IP moat: 82 patents · Soonicorn
Audience (LinkedIn): 10k LinkedIn followers — 2.6% of this cohort's audience
Hiring (LinkedIn): 2 hiring posts in 12 mo (public) · momentum +2 · hiring: Associate Director of Global Quality, Senior Quality Control Manager
Funding rounds
  • Jan 2026Series C$24M
  • Jun 2025Series C$56M
  • Jul 2024Series B$6M
  • Jun 2022Venture Debt$40M
Founders & team
Christina SmolkeCo-Founder & CEOKristy HawkinsCo-Founder & CSO
Investors
Viking Global Investors, Sherpalo Ventures, In-Q-Tel, Echo, Oxford Finance, SVB
Tech stack
BabelCloudflareCloudflare Bot ManagementCookieyesCore-JsElementor
#2
Series C · Palo Alto, California · founded 2010 · 20 employees
$65Mraised
▾

Developer of medical devices for treating mitral valve regurgitation. The company is developing a minimally-invasive trans-catheter hemi-replacement system, PLAR system, to treat insufficiency in the function of the mitral valve.

Funding rounds
  • Mar 2026Series C$50M
  • Jun 2020Series B$40M
  • Jul 2018Series A$25M
Founders & team
Jacques EssingerFounder & CEOJacques EssingerCEO
Investors
Decheng Capital, Endeavour Vision, IDO Investments, Earlybird, Wellington Partners Venture Capital, Longitude Capital
#3
Series A · Palo Alto, California · founded 2021
$20.3Mraised
▾

Developer of protein sequencing technology using silicon photonics and machine learning. The company focuses on high-resolution protein analysis, including sequence, post-translational modifications, structure, and interactions. It aims to provide insights into the proteome to address challenges in personal, population, and ecosystem health. The technology amplifies light to analyze proteins without relying on sample amplification or fluorescent tags. The goal is to enable proactive solutions in medicine and sustainability.

Fliar Intelligence Index™ 67how this company ranks against its industry peers
Talent
top 35%
Funding
top 36%
AI
top 45%
Global
bottom 33%
Talent: 3 named leaders on record
Funding: Raised $20.3M across 2 rounds · 2 rounds over 1 yrs (2.0/yr) · Last round Series A (May 2026)
AI: Product described with: machine learning
Funding rounds
  • May 2026Series A$20M
  • Apr 2025Grant (prize money)$289.9K
Founders & team
Jennifer DionneCo-FounderJack HuCo-FounderNhat VuCo-Founder
Investors
HHS, NFX, Future Ventures, Base4 Capital, Analog Devices, Stanford University
#4
Late Stage · Palo Alto, California · founded 2024
$50Mraised
▾

Developer of therapeutics for retinal disorders. It offers a lead product, TH103 which is a fully humanized, recombinant fusion protein designed for intravitreal delivery as anti-VEGF agent for the treatment of neovascular age-related macular degeneration.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 6k LinkedIn followers
Funding rounds
  • Dec 2025Post IPO$50M
Founders & team
Srinivas AkkarajuCo-Founder & DirectorNapoleone FerraraCo-FounderSamir PatelCo-Founder
Investors
ADAR1, Coastlands Capital, RTW Investments, Samsara BioCapital, Woodline Partners, Invus
#5
Acquired · Palo Alto, California · founded 2020
$70Mraised
▾

Developer of trifunctional effector cell response inhibitors for allergic diseases. It focuses on advancing beyond traditional anti-IgE approaches. The company targets IgE bound to the effector cell, the source of allergic signaling. It aims to improve patient quality of life by combating severe allergic diseases.

Funding rounds
  • Oct 2025Series A$70M
Founders & team
Theodore JardetzkyCo-FounderAlexander EggelCo-FounderGeoff HarrisCo-Founder & Chief Scientific Officer
Investors
Samsara BioCapital, Red Tree Venture Capital, Decheng Capital
Tech stack
Anime.JsCloudflareCloudflare Browser InsightsCloudflare StreamCookieyesCore-Js
#6
Series C · Palo Alto, California · founded 2017 · 41 employees
$37Mraised
▾

Developer of embryology diagnosis device for professionals. It offers DaVitri an automated platform designed to modernize egg freezing and embryo warming workflows, automates critical timing and cryoprotectant exposure steps for improved consistency and oocyte survival rates. It also offers m|z test an AI powered metabolomic test designed for non-invasive embryo selection.

Fliar Intelligence Index™ 67how this company ranks against its industry peers
Patents
top 26%
AI
top 28%
Talent
top 28%
Funding
top 29%
Moat
top 31%
Innovation
top 32%
Patents: 44 patents matched (strict assignee match) · 34 filings since 2022 vs 10 in 2017-21 · Latest publication 2026
AI: Holds AI/ML patents (G06N-family CPC) · Product described with: ai powered
Talent: 4 named leaders on record · 4 C-suite/founder profiles curated
Audience (LinkedIn): 12k LinkedIn followers — 3.1% of this cohort's audience
Activity (LinkedIn): 1 product launches · 1 partnerships (incl. TekServis Ltd. ti.) announced in 12 mo
Funding rounds
  • Nov 2025Conventional Debt$23M
  • Apr 2025Series C$20.6M
  • May 2021Series B$15M
  • Dec 2018Series A$13.6M
Founders & team
Jose HorcajadasCo-Founder & Chief Scientific OfficerSantiago MunneCo-Founder & CIOMartin VarsavskyCo-Founder & Chairman
Investors
Octopus Ventures, Google Ventures, Khosla Ventures, Felicis Ventures, Overwater Ventures, European Investment Bank
Tech stack
Amazon CloudfrontAmazon S3Amazon Web ServicesCdnjsCloudflareCloudflare Bot Management
#7
Series A · Palo Alto, California · founded 2009 · 2 employees
$25.6Mraised
▾

Developer of therapies for treating neurological disorders. The company is developing therapies for treating neurological disorders (migraine and epilepsy) in collaboration with the University of California. The lead candidate of the company, EP-102, is an oral treatment for acute migraine. It is a short-acting benzodiazepine and acts on gamma-aminobutyric acid (GABA) receptors.

Funding rounds
  • Oct 2025Series A$1.2M
  • Dec 2024Series A$4M
  • Oct 2022Series A$4.3M
  • Dec 2020Series A$20.3M
Founders & team
Brendan MagrabCEO
#8
Series B · Palo Alto, California · founded 2021 · 10 employees
$151.6Mraised
▾

Developer of therapeutics for multiple metabolic diseases. It offer drug cangidates that target central pathways of energy metabolism which include ACC2 inhibitor TLC-3595 for type-2 diabetes, LXR inverse agonist TLC-2716 for Severe Dyslipidemias, Mitochondrial protonophore TLC-6740, and TLC-1235 for Lipodystrophies.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 3k LinkedIn followers
Funding rounds
  • Feb 2025Series B$1.7M
  • Feb 2025Grant (prize money)$2.3M
  • Aug 2024Series B$67M
  • Oct 2023Series A$84.6M
Investors
Longitude Capital, Enavate Sciences, Samsara BioCapital, NuevaBio, Lilly, Ascenta Capital
#9
Series A · Palo Alto, California · founded 2018 · 19 employees
$17.2Mraised
▾

Developer of therapeutics for the treatment of inflammatory and rare diseases. The company's platform is utilizing the drug development cycle by applying AI to multiple-mechanism-of-action protein targets and their natural platform to create novel therapies for rare and inflammatory diseases. The lead candidate molecule is "GEn-1124"- for lung chronic conditions and other candidate molecules are in the research and discovery phase.

Funding rounds
  • Oct 2025Series A$5.5M
  • Dec 2022Series A$17M
  • 2021Seed—
  • Aug 2019Seed$125K
Founders & team
Ritu LalCo-Founder & CEO
Investors
Clear Ventures, Y Combinator, SV Latam Capital, Khosla Ventures, Neue Fund, Harmonix
#10
Public · Palo Alto, California · founded 2012 · 95 employees
$30Mraised
▾

Therapeutic antibody discovery company providing diverse antibody repertoires and cutting-edge screening technologies. They empower pharmaceutical partners with access to advanced antibody discovery platforms for next-generation therapeutics. They offer validated transgenic animals capable of generating high-quality, fully human antibodies. Their technology includes heavy chain-only transgenic chicken for diverse antibody repertoires. They provide antibody generation, antigen design, bispecific platforms, xPloration screening, and antibody optimization services. They also offer Fc-silencing, ion channel, transporter, and in silico technologies. They focus on partnerships to advance clinical drug development. They provide antibody discovery services.

Fliar Intelligence Index™ 48how this company ranks against its industry peers
Patents
top 25%
Innovation
top 33%
Funding
top 36%
Tech
top 42%
Market
top 46%
Moat
top 48%
Patents: 30 patents matched (strict assignee match) · 29 filings since 2022 vs 1 in 2017-21 · Latest publication 2026
Innovation: 30 patents (top 42% of patent-holders) · 29 filings since 2022 vs 1 in 2017-21
Funding: Raised $30.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) · Last round Post IPO (Aug 2025)
Funding rounds
  • Aug 2025Post IPO$30M
Tech stack
Apple Icloud MailAstraCallrailCloudflareCloudflare Bot ManagementCloudflare Browser Insights
#11
Series B · Palo Alto, California · founded 2018 · 47 employees
$138.1Mraised
▾

Developer of RNA biomarkers and AI platform for cancer detection. It focuses on identifying signals from RNA to gain clinical insights. The platform aims to revolutionize cancer diagnosis, treatment, and management. It utilizes novel RNA biomarkers and artificial intelligence to connect previously unseen clinical insights.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 6k LinkedIn followers
Hiring: 1 hiring post in 12 mo (public)
Activity: 2 product launches · 1 partnerships (incl. Deviation Capital) announced in 12 mo
Funding rounds
  • Sep 2024Grant (prize money)$1.3M
  • Oct 2022Series B$70.6M
  • Dec 2021Series A$67.5M
Founders & team
Babak AlipanahiCo-Founder & Chief Scientific OfficerHani GoodarziCo-Founder
Investors
Casdin Capital, Two Sigma Ventures, S32, HHS, BVF
#12
Acquired · Palo Alto, California · founded 2015 · 383 employees
$434.2Mraised
▾

Developer of therapeutics for the treatment of genetic diseases. It utilizes a mapping of various genetic disease landscapes to identify opportunities for therapeutic intervention. The company's drug candidates include PTCH1-inhibitor for Gorlin syndrome and S1P-lyase inhibitor for Darier disease and Hailey-Hailey disease and others.

LinkedIn Pulse recent public activity · Jul 2026
Audience: 81k LinkedIn followers — 21.0% of this cohort's audience
Activity: 1 awards announced in 12 mo
Funding rounds
  • Apr 2024Post IPO$200M
  • Feb 2021Post IPO$4.5M
  • Jan 2021Post IPO$650M
  • Jan 2019Series D$299.2M
Founders & team
Neil KumarCo-Founder & CEOFrank McCormickCo-Founder
Investors
KKR, Viking Global Investors, Perceptive Advisors, AIG, Hercules Capital, Aisling Capital
Tech stack
Amazon CloudfrontAmazon Web ServicesApple Icloud MailCloudflareCloudflare Bot ManagementContentful

Funding & investor landscape

$4.7Btotal disclosed funding
96companies funded
293disclosed rounds
1rounds last 90 days
Most active investors
HHS19 rounds
Y Combinator7 rounds
Alta Partners4 rounds
Andreessen Horowitz4 rounds
Arch Venture Partners4 rounds
Asset Management Ventures4 rounds
Google Ventures4 rounds
Lightspeed Venture Partners4 rounds
Morningside4 rounds
AME Cloud Ventures3 rounds

Notable founders

Christina Smolke
Co-Founder & CEO · Antheia
Kristy Hawkins
Co-Founder & CSO · Antheia
Jacques Essinger
Founder & CEO · Polares Medical
Jennifer Dionne
Co-Founder · Pumpkinseed
Jack Hu
Co-Founder · Pumpkinseed
Srinivas Akkaraju
Co-Founder & Director · Kalaris Therapeutics
Napoleone Ferrara
Co-Founder · Kalaris Therapeutics
Theodore Jardetzky
Co-Founder · Excellergy
Alexander Eggel
Co-Founder · Excellergy
Jose Horcajadas
Co-Founder & Chief Scientific Officer · Overture Life
Santiago Munne
Co-Founder & CIO · Overture Life
Brendan Magrab
CEO · Epalex
Prism market signals · United States · country-scoped Prism corpus, 1,465,538 docs

Market landscape — 10 sub-themes by coverage

Share of Life Sciences coverage by sub-theme.

Regulatory-risk over time rising

Funding & growth over time

funding rising · growth rising

RESEARCH SIGNALS · United States

How research on Biotechnology is moving in the United States

A read on the academic research around Biotechnology — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 6,260 United States-affiliated papers.

research sentiment over time
200820162026
enthusiastic · positive · guarded tone
Tone is overwhelmingly optimistic and steady — the enthusiastic (strongly-positive) share moved 44% → 42% across 2008–2026.
top research entities
  • Harvard University209
  • Cornell University177
  • University of Tennessee at Chattanooga140
  • Howard Hughes Medical Institute126
  • Johns Hopkins University121
leading researchers
Stylianos Chatzimanolis · TARIK DEDOVIC · KATH-RYN ANN F. HANKINS · Christoforos Pavlou · Giannis Bolanakis · Ashley R Tetens · Tyler Findlay · Jordyn Craig-Schwartz
▲ Breakthroughs2,038 · 33%
▼ 41%→30% share
▼0.7× share momentum0 median citations71% since 2021mostly empirical
Gene-focused breakthrough research is surging — papers rose from 33 to 164 while three sub-topics including Identification and Reporter gene emerged brand-new.
rising sub-themes (early→recent)
  • Gene33→164
  • Transcription (linguistics)11→79
  • Antibody11→62
  • Genome6→56
  • Mutation7→56
Newly emergingIdentification (biology) 0→18 · Function (biology) 0→18 · Reporter gene 0→16
Landmark U1 snRNP regulates cancer cell migration and invasion in vitro · 7,224 cites
◆ Advancements2,118 · 34%
▲ 29%→35% share
▲1.2× share momentum0 median citations80% since 2021mostly empirical
Cell culture and fermentation advancements are intensifying — papers jumped from 3→62 and 2→54 respectively as Advancements field-share grew to 35%.
rising sub-themes (early→recent)
  • Gene8→110
  • Cell culture3→62
  • Gene expression3→62
  • Fermentation2→54
  • Downregulation and upregulation1→50
Newly emergingIdentification (biology) 0→27 · Probiotic 0→24 · Cultivar 0→23
Landmark Using Deep Learning for Image-Based Plant Disease Detection · 4,262 cites
▼ Concerns1,006 · 16%
▼ 17%→15% share
▼0.9× share momentum0 median citations73% since 2021mostly empirical
Antibiotic resistance concern is escalating — papers tripled from 15 to 45 alongside newly emerging Animal health and Integrated pest management signals.
rising sub-themes (early→recent)
  • Agriculture19→58
  • Antibiotic resistance15→45
  • Public health4→31
  • Gene6→30
  • Production (economics)5→29
Newly emergingQuality (philosophy) 0→27 · Animal health 0→14 · Integrated pest management 0→13
Landmark The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate · 8,812 cites
RESEARCH HOTSPOTS · United States

Where biotechnology is researched across United States

Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.

Boston351 · +0.52
Hot · Cancer researchAdvancing · Nucleic acidOpportunity · Strain (injury)Concern · Antibiotics
New York319 · +0.47
Hot · GermplasmAdvancing · Genomic selectionOpportunity · CellConcern · Agriculture
SF Bay Area235 · +0.57
Hot · Near-infrared spectroscopyAdvancing · Fluorescence-lifetime imaging microscopyOpportunity · ReceptorConcern · Biochemical engineering
Philadelphia115 · +0.60
Hot · Chimeric antigen receptorAdvancing · Genetically modified mouseOpportunity · Transgene
San Diego101 · +0.59
Hot · Recombinant DNAAdvancing · Gene knockdownOpportunity · Cell cultureConcern · Cancer cell
Seattle95 · +0.46
Hot · Polymerase chain reactionAdvancing · Monoclonal antibodyOpportunity · Downregulation and upregulation
Chicago95 · +0.57
Hot · AntigenAdvancing · Untranslated regionOpportunity · Transcription factor
Los Angeles93 · +0.61
Hot · NucleaseAdvancing · GenomicsOpportunity · Cell
Pittsburgh65 · +0.54
Hot · MutationAdvancing · Nucleic acidOpportunity · Gene
Ann Arbor65 · +0.58
Hot · Cell cultureAdvancing · Identification (biology)Opportunity · Mutant
PATENT SIGNAL · United States

Who's filing biotechnology patents in the United States

United States biotechnology patent filing is accelerating — 457,918 filings from 8,000 assignees (2016–2025), led by Genentech, UNIV California, Regeneron Pharma; annual filings 36884→44446.

457,918 filings8,000 assigneespeak 51616/yr2016–2025
filing momentum (YoY 2016–2025)
top patent filers
  • Genentech18103
  • UNIV California17969
  • Regeneron Pharma16083
  • Amgen10510
  • Monsanto Technology9754
  • UNIV Pennsylvania8526
  • Harvard College7463
  • UNIV Texas7382

Common questions

How many Life Sciences companies are there in Palo Alto, United States?
Radar tracks 165 indexable Life Sciences companies headquartered in Palo Alto, United States that meet our profile-completeness bar.
What is the total funding raised by Life Sciences companies in Palo Alto, United States?
The Life Sciences companies in Palo Alto, United States on this list have raised a combined $4.7B in disclosed equity funding across 96 funded companies.
Which is the highest-funded Life Sciences company in Palo Alto, United States?
Medable is the highest-funded Life Sciences company in Palo Alto, United States, with $521M in disclosed equity funding.
How many Life Sciences companies in Palo Alto, United States are funded?
96 of the 165 Life Sciences companies in Palo Alto, United States on this list have disclosed at least one equity funding round.
How many Life Sciences unicorns are there in Palo Alto, United States?
1 Life Sciences company in Palo Alto, United States on this list is valued at $1B or more.
Who are the top investors in Palo Alto, United States Life Sciences companies?
The most active investors in Palo Alto, United States Life Sciences companies on this list include HHS, Y Combinator, Alta Partners, Andreessen Horowitz, Arch Venture Partners.
Riya SenguptaFinancials

Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.

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