Best HealthTech Companies in State of Hessen, Germany
The 59 best HealthTech companies in State of Hessen, Germany in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: COBI.bike.
Our analysis of 50 HealthTech companies
$1.6b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best HealthTech companies in State of Hessen
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | COBI.bike Smart connected biking system | $12M | 125 mo ago | Acqui-Hired | — | 2014 | Vue.jsAmazon Web ServicesModernizr+1 | 4 patents E‑bike control interfaces, passive‑switch battery management, and vehicle control electronics. | — |
| 2 | CardioSecur Heart health monitoring device | $9M | 113 mo ago | Series B | — | 2008 | Cart FunctionalityTYPO3 CMSOdoo+22 | — | — |
| 3 | Ankaadia Provider of recruitment management software for healthcare organizations | $2M | 37 mo ago | Seed | Fabio Enge Co-Founder | 2021 | WebflowCart FunctionalityApple iCloud Mail+13 | — | — |
| 4 | IDMP1 Provider of clinical management software for hospitals | $174K | 79 mo ago | Funding Raised | — | 2015 | — | — | — |
| 5 | STRAFFR Smart resistance band for tracking exercise data | $20K | 48 mo ago | Seed | Torben Hellmuth Co-Founder & CTO | 2017 | — | 5 patents Smart elastic resistance bands for sports training with integrated force sensing. | — |
| 6 | Curia Provider of an online information platform for cancer and patient sourcing for clinical trials | — | 72 mo ago | Funding Raised | — | 2019 | — | — | — |
| 7 | CrystalsFirst Provider of protein crystals and machine learning for biopharmaceutical industry | — | 85 mo ago | Funding Raised | Serghei Glinca Co-Founder & CEO | 2018 | — | 9 patents Optimizing small‑molecule soaking conditions for macromolecular crystal structure determination | 1 launch |
| 8 | Innoplexus AI-based life Sciences company that provides solutions for discovering and developing safer and more… | — | 86 mo ago | Series C | Gunjan Bhardwaj Co-Founder & CEO | 2011 | Node.jsZohoTailwind CSS+12 | 218 patents Patents concentrated in computing, sensing & instrumentation | — |
Top 9 HealthTech companies in State of Hessen
#1
Seed · Oberursel, State of Hessen · founded 2021 · 11 employees$1.9Mraised▾
Provider of recruitment management software for healthcare organizations. The company offers a state-of-the-art SaaS application ("Software-as-a-Service"), for service agencies, institutions in the health and care sector, and international nursing professionals to digitize the recruitment process.
- Jun 2023Seed$1.9M
#2
Acqui-Hired · Frankfurt, State of Hessen · founded 2014 · 35 employees$11.8Mraised▾
COBI developed a smart biking system consisting of a smartphone app and other hardware for safe and convenient biking experience. Features of the system include navigation and weather, Automatic front- and rear-light with collision avoidance, music streaming control, fitness tracking, phone calls among others.
- Jan 2016Series A$6.9M
- Apr 2015Series A$4.2M
- Apr 2014Seed$688.4K
#3
Series B · Frankfurt, State of Hessen · founded 2008 · 14 employees$8.6Mraised▾
CardioSecur offers a mobile EKG device for monitoring heart health. Device consists of 4 disposable electrodes connected a mobile app which can record clinic-quality 15-lead ECG. App can monitor the data for any abnormalities and recommend further doctor consultation if required.
- Jan 2017Series B$5.3M
- Jan 2016Series A—
- Apr 2013Series A$3.3M
- Nov 2010Seed—
#4
Seed · Kassel, State of Hessen · founded 2017 · 9 employees$20Kraised▾
STRAFFR has developed a smart resistance band for tracking the exercise data. The smart resistance band is connected to the app which provides training instructions, analyses the tracked training data to provide insights and real-time feedback and statistics.
- 2022Seed$20K
#5
Funding Raised · Bad Vilbel, State of Hessen · founded 2015$173.6Kraised▾
Provider of clinical management software for hospitals
- Dec 2019Grant (prize money)$173.6K
#6
Funding Raised · Eschborn, State of Hessen · founded 2019 · 25 employees—raised▾
Provider of an online information platform for cancer and patient sourcing for clinical trials. The app provides information on therapies, drugs, clinical trials, and experts, based on cancer profiles. Users can access recruiting clinical trials based on cancer type by answering a few questions and can track the progress of an application.
- 2020Grant (prize money)—
#7
Funding Raised · Marburg, State of Hessen · founded 2018 · 15 employees—raised▾
CrystalsFirst is a provider of crystals and machine learning for biopharmaceutical industry. It has developed proprietary scaling lab technology using protein crystals and machine learning. Its proprietary technology helps in the potential of 3D-models for structure-guided drug design and meets the high demand for bio-structural data to tailor the compounds for high affinity, selectivity, safety, and efficacy. It helps to identify new modes of action for drug candidates, enter design paths of the allosteric modulators and increase the efficiency of the drug pipeline.
- May 2019Grant (prize money)—
#8
Series C · Eschborn, State of Hessen · founded 2011 · 141 employees—raised▾
AI-based life Sciences company that provides solutions for discovering and developing safer and more successful medicines by leveraging its proprietary ontosight AI search platform.
- Apr 2019Series C—
- Dec 2016Seed—
#9
Acquired · Giessen, State of Hessen · founded 1992 · 141 employees$551.6Mraised▾
Alcedis offers IT solutions and services for clinical research. It offers AlcedisTRIAL - software for clinical research. Alcedis offers the AlcedisTRIAL – CTMS - Clinical Trial Management System, AlcedisTRIAL – eCRF - electronic Case Report Form, AlcedisTRIAL – Plugins, AlcedisTRIAL – Mobile -mobile software systems for clinical research, and AlcedisACADEMY training software. Plugins can be selected as per requirement and the system customised to suit the need of the trial. It acts as a Contract Research Organization (CRO) and offers clinical trial services.
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of HealthTech coverage by sub-theme.
Regulatory-risk over time flat
Funding & growth over time
funding rising · growth rising
How research on Digital Health is moving in Germany
A read on the academic research around Digital Health — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,976 Germany-affiliated papers.
- Charité - Universitätsmedizin Berlin161
- Heidelberg University147
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin82
- Technical University of Munich76
- Friedrich-Alexander-Universität Erlangen-Nürnberg73
- Health informatics1→28
- Wearable computer3→18
- Context (archaeology)1→11
- Photoplethysmogram1→10
- Psychological intervention1→8
- Health informatics8→118
- Health care5→106
- Public health2→60
- Psychological intervention2→60
- Intervention (counseling)1→49
- Health care11→278
- Health informatics31→192
- Public health14→120
- Psychological intervention2→91
- Health administration24→100
Where digital health is researched across Germany
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing medical devices patents in Germany
Germany medical devices patent filing is cooling — 97,357 filings from 8,000 assignees (2016–2025), led by Siemens, Sanofi Aventis Deutschland, Aesculap; annual filings 10817→8851.
- Siemens18029
- Sanofi Aventis Deutschland10212
- Aesculap4911
- Zeiss CARL Meditec4291
- Fresenius Medical CARE Deutschla4185
- Hoffmann LA Roche2978
- Fresenius Medical CARE DE2692
- Biotronik SE & KG2562
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.