Best High Tech Companies in Cleveland, United States
The 37 best High Tech companies in Cleveland, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: SPR Therapeutics.
Our analysis of 306 High Tech companies
$95.7b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best High Tech companies in Cleveland
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | SPR Therapeutics Peripheral nerve stimulation therapy for treating pain | $174M | 31 mo ago | Series D | Maria E Bennett Founder & CEO | 2010 | — | 220 patents Implantable neurostimulation systems for chronic and back pain relief | — |
| 2 | GL Neurotech Developer of bioinstrumentation products for physiological monitoring and therapy | $18M | 20 mo ago | Funding Raised | Robert Schmidt Chairman and CEO | 2010 | — | — | — |
| 3 | NeuroWave Systems Neurodiagnostic device and accessories | $13M | 86 mo ago | Funding Raised | — | 2003 | Apache HTTP ServerStatcounterGoogle Analytics+2 | — | — |
| 4 | PowdermetInc Advanced materials R&D: nanotechnology, clean energy, and sustainable solutions | $2M | 16 mo ago | Funding Raised | — | 1996 | — | — | — |
| 5 | RoadPrintz Provider of robotic road painting solution | $2M | 15 mo ago | Funding Raised | Sam Bell President & Co-Founder | 2017 | WordPressMySQLZoho+18 | — | — |
| 6 | NimbusWeb Provider of AI powered portals for internal and external collaboration | $700K | 25 mo ago | Seed | Pavel Sher Founder & CEO | 2023 | WordPressMySQLPHP+23 | — | — |
| 7 | Solace Vision Platform offering software to build metaverses | $100K | 39 mo ago | Seed | — | 2020 | — | — | — |
| 8 | HotEnd Works Insights on faith-based investing, presentation tools, and industry trends | $40K | 115 mo ago | Deadpooled | Benjamin Becker CEO & MD | 2012 | — | — | — |
Top 11 High Tech companies in Cleveland
#1
Funding Raised · Cleveland, Ohio · founded 2010 · 15 employees$17.9Mraised▾
Developer of bioinstrumentation products for physiological monitoring and therapy. The products include physiological monitors and patient-centered diagnostic and therapy systems integrated with wireless, remote, and web-based applications. The companys offerings support research and education, focusing on movement disorders like parkinsons disease, telemedicine, and in-home health monitoring. Manufacturing, distribution, and export of research systems and medical devices are also core business activities.
- Jan 2025Grant (prize money)$1.7M
- Sep 2023Grant (prize money)$289.5K
- Sep 2018Grant (prize money)$1.7M
- Jul 2018Grant (prize money)$224.7K
#2
Funding Raised · Cleveland, Ohio · founded 1996 · 13 employees$2.1Mraised▾
Advanced materials R&D: nanotechnology, clean energy, and sustainable solutions. The company develops and transitions breakthrough materials innovations, enabling reduced weight, resource consumption, and environmental footprint. They increase energy efficiency through engineered nano-scale features and hierarchically structured metal and/or ceramic phases. The company offers toll processing services, contract R&D, and a diverse line of unique products. They bridge the gap between lab bench and pilot production, focusing on clean, sustainable, energy, and life-saving advanced materials solutions. Their expertise lies in CVD, milling, furnace, and processing equipment, catering to a broad range of markets and end-users. The company is committed to advancing materials science for a sustainable future.
- Apr 2025Grant (prize money)$1.4M
- Jun 2012Grant (prize money)$150K
- Feb 2012Grant (prize money)$149.8K
- May 2011Grant (prize money)$150K
#3
Funding Raised · Cleveland, Ohio · founded 2017 · 3 employees$1.7Mraised▾
RoadPrintz is a manufacturer of robotic road painting equipment. The machine uses proprietary Dragon Drop technology that allows engineers to specify and apply paint schemes for road painting and pavement markings. Claims that its machine will first perform survey and then map the area to start painting, and repainting activities for signs like turn arrows, diagonal buffers, lane separators and more.
- May 2025Grant (prize money)$1.4M
- Jan 2022Grant (prize money)—
- May 2020Grant (prize money)$224.6K
- Oct 2019Grant (prize money)$75K
#4
Series D · Cleveland, Ohio · founded 2010 · 198 employees$173.9Mraised▾
Developer of a peripheral nerve stimulation therapy platform designed to treat severe pain. The company offers a non-narcotic, reversible, safe, effective, and affordable alternative to addictive opioid medications and invasive surgeries for acute and chronic pain management, enabling patients to get sustained and significant pain relief.
#5
Seed · Cleveland, Ohio · founded 2023 · 45 employees$700Kraised▾
Provider of AI powered portals for internal and external collaboration. These portals facilitate client, sales, partner, and onboarding processes. The platform incorporates AI agents for automated task management, improving efficiency and streamlining workflows. Customizable templates and integrations with existing systems are offered, enabling seamless personalization and optimization. The solution aims to consolidate various tools into a unified platform, enhancing communication and collaboration across teams and clients. AI-driven features automate tasks such as meeting transcription, proposal generation, and partner onboarding, accelerating processes and improving overall operational efficiency.
- Aug 2024Seed$700K
#6
Funding Raised · Cleveland, Ohio · founded 2003 · 15 employees$13.3Mraised▾
NeuroWave Systems develops neurodiagnostic and monitoring devices. The company's focus is on peri-operative neuromonitoring, seizure detection, and sleep architecture assessment. The NeuroSENSE Monitor is a bilateral brain monitor with EasyPrep electrodes. The company is ISO 13485 certified. The products are available in markets where the CE mark is recognized.
- Jul 2019Grant (prize money)$244.6K
- Sep 2014Grant (prize money)$1.5M
- Sep 2013Grant (prize money)$354.7K
- Jun 2010Grant (prize money)$499.8K
#7
Seed · Cleveland, Ohio · founded 2020 · 4 employees$100Kraised▾
Platform offering software to build metaverses. The platform offers no code development tool that enables businesses to virtual environments. The software helps to automate environment development and supports customization of the environment as per requirements.
- 2023Seed$100K
#8
Funding Raised · Cleveland, Ohio · founded 2019$25Kraised▾
Provider of IoT solutions to gauge equipment health and performance. The IIoT platform uses wireless sensor nodes and is used to augment industrial, manufacturing and power generation sectors. Also offers a self-powered sensor device and a software dashboard for predictive maintenance and downtime mitigation.
- Sep 2020Grant (prize money)$25K
#9
Funding Raised · Cleveland, Ohio · founded 2018 · 2 employees$25Kraised▾
Prophit.ai provides e-invoicing compliance software for businesses. It features AI-based solutions for invoice auditing and compliance. It offers algorithms for tax evaluation.
- Dec 2019Grant (prize money)$25K
#10
Deadpooled · Cleveland, Ohio · founded 2012 · 3 employees$40Kraised▾
Insights on faith-based investing, presentation tools, and industry trends. The company provides insights into Christian investing, guiding individuals to align their finances with their faith through socially responsible and impact investing. It explores tools for creating engaging cartoon presentations, offering a creative solution for effective communication. The platform also delivers updates on diverse industry trends, from commercial vehicles to construction materials and workspace design, offering valuable information for professionals and enthusiasts alike. The company promotes socially responsible investing and offers creative presentation solutions.
- Jan 2017Grant (prize money)$40K
#11
Seed · Cleveland, Ohio · founded 2015 · 619 employees$25Kraised▾
Revolutionizing consumer experience with mobile app, beacons, and content management. This technology company offers a platform connecting businesses and consumers through Bluetooth beacon technology and a mobile application. Business subscribers can utilize a content management system to upload custom content and connect it to strategically placed beacons within their establishments. When consumers with the mobile app are within range of these beacons, they receive information via push notifications. This system provides businesses with valuable customer metrics and analytics to increase productivity, reduce costs, and improve profitability. The platform offers a subscription-based service, providing a comprehensive solution for businesses to engage with their customers in a more personalized and informative way.
- 2015Seed$25K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of High Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Semiconductors is moving in the United States
A read on the academic research around Semiconductors — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 8,739 United States-affiliated papers.
- Georgia Institute of Technology489
- IMEC343
- Intel325
- Purdue University West Lafayette218
- Industrial Technology Research Institute177
- Photonics56→121
- Photonic integrated circuit49→81
- Artificial neural network3→29
- Detector25→48
- Scalability53→73
- Photonics45→59
- Artificial neural network2→14
- Rapid single flux quantum2→12
- Detector20→29
- Image sensor2→11
- Photonics10→28
- Hardware security module6→13
- Thermal10→16
- Automotive industry2→8
- Photonic integrated circuit9→14
Where semiconductors is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing semiconductors patents in the United States
United States semiconductors patent filing is cooling — 112,775 filings from 8,000 assignees (2016–2025), led by IBM, Applied Materials, Intel; annual filings 11572→7675.
- IBM19691
- Applied Materials13119
- Intel11689
- Micron Technology10011
- Texas Instruments4804
- LAM RES4667
- Sandisk Technologies3051
- Qualcomm2897