Best Life Sciences Companies in Auvergne Rhone Alpes, France
The 194 best Life Sciences companies in Auvergne Rhone Alpes, France in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Amolyt Pharma.
Our analysis of 50 Life Sciences companies
$3.3b in tracked funding; 62% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Life Sciences companies in Auvergne Rhone Alpes
| # | Company | Disclosed funding | Last round | Stage | Employees | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Amolyt Pharma Developer of peptide therapeutics to treat rare endocrine and metabolic disorders | $292M | 41 mo ago | Acquired | 6 | 2015 | — | — | — |
| 2 | Valneva Developer of prophylactic vaccines for infectious diseases | $144M | 44 mo ago | Public | 719 | 1999 | WordPressMySQLPHP+24 | 195 patents Viral vaccine production and subunit vaccine formulation for chikungunya and respiratory pathogens | — |
| 3 | eCential Robotics Developer of robotic surgery platform combining imaging, navigation, and robotic assistance | $133M | 65 mo ago | Series C | 132 | 2009 | Craft CMSPHPUbuntu+11 | 115 patents Image-guided surgical robotics for orthopedic procedures with real-time tracking and planning | — |
| 4 | Diabeloop Developer of automated and personalized systems for type 1 diabetes 72Innovation top 15%Patents top 20%AI top 20%Moat top 21% All 11 signals ▾Innovationtop 15% Patentstop 20% AItop 20% Moattop 21% Fundingtop 31% Growthtop 45% Talentbottom 49% Marketbottom 47% Techbottom 47% Globalbottom 42% Newsbottom 27% Innovation: 65 patents (top 15% of patent-holders) · 57 filings since 2022 vs 8 in 2017-21 Patents: 65 patents matched (strict assignee match) · 57 filings since 2022 vs 8 in 2017-21 rank vs industry peers · Fliar Intelligence Index 72/100 | $124M | 48 mo ago | Series C | 158 | 2015 | WordPressApple iCloud MailGoogle Workspace+19 | 65 patents Closed-loop glucose monitoring and insulin dosing algorithms for diabetes management | 3 launchs · 1 partnership |
| 5 | Enyo Pharma Developer of therapeutics for diseases with impaired kidney function 60Patents top 20%Innovation top 21%Funding top 25%Moat top 26% All 9 signals ▾Patentstop 20% Innovationtop 21% Fundingtop 25% Moattop 26% Growthtop 45% Techbottom 49% Globalbottom 43% Marketbottom 40% Newsbottom 27% Patents: 164 patents matched (strict assignee match) · 114 filings since 2022 vs 50 in 2017-21 Innovation: 164 patents (top 16% of patent-holders) · 114 filings since 2022 vs 50 in 2017-21 rank vs industry peers · Fliar Intelligence Index 60/100 | $113M | 12 mo ago | Series C | 34 | 2014 | WordPress Block EditorWordPressMySQL+18 | 164 patents Novel antiviral small‑molecule salts and FXR‑agonist combos for hepatitis D therapy | — |
| 6 | UroMems Developer of active implantable devices for urological incontinence 72Funding top 21%Tech top 25%Patents top 27%Innovation top 28% All 9 signals ▾Fundingtop 21% Techtop 25% Patentstop 27% Innovationtop 28% Moattop 29% Growthtop 35% Globalbottom 43% Marketbottom 42% Newsbottom 22% Funding: Raised $85.7M across 6 rounds · 6 rounds over 10 yrs (0.6/yr) Tech: 33 technologies across 5/8 capability areas · Cloud: Cloudflare rank vs industry peers · Fliar Intelligence Index 72/100 | $86M | 1 mo ago | Series D | 49 | 2011 | WordPressMySQLPHP+21 | 173 patents Implantable occlusive devices and control systems for sealing anatomical ducts and protecting sensors | 3 job openings · 1 internship |
| 7 | Biom'Up Developer of hemostatic products for surgical applications | $84M | 82 mo ago | Public | 104 | 2005 | — | 59 patents Hemostatic powders and collagen-based wound sealing devices for surgical bleeding control | — |
| 8 | Inova Cloud-based biopharma CRM and CRO collaborating system for the life science industry | $71M | 59 mo ago | Series C | 137 | 2010 | — | 5 patents Heat‑resistant culinary apparel with elastic closures for improved chef comfort | — |
| 9 | PDC*line Pharma Developer of therapeutic vaccines for the treatment of cancer | $65M | 54 mo ago | Series B | 34 | 2014 | DrupalPHPGoogle Maps+13 | — | — |
| 10 | Advanced Accelerator Applications Novartis company, developing molecular nuclear medicine theranostics | $56M | 134 mo ago | Acquired | 1,038 | 2002 | DrupalPHPVideoJS+16 | 215 patents Formulating stable, concentrated radiopharmaceutical complexes for diagnostic and therapeutic use. | — |
| 11 | EYE TECH CARE Developer of ultrasound device to treat glaucoma | $52M | 45 mo ago | Series D | 19 | 2008 | TYPO3 CMSPHPBootstrap+7 | 111 patents Patents concentrated in health & consumer products | — |
| 12 | Poxel Developer of therapeutic solutions for the treatment of Type 2 diabetes | $50M | 46 mo ago | Public | 37 | 2009 | BootstrapApache HTTP ServerjQuery+7 | 338 patents Deuterated small‑molecule drugs targeting metabolic, neurological and rare genetic disorders. | — |
| 13 | MaaT Pharma Developer of microbiome therapy for the treatment of intestinal dysbiosis diseases | $42M | 59 mo ago | Public | 71 | 2014 | WordPressMySQLPHP+25 | 171 patents Patents concentrated in health & consumer products | 1 internship |
| 14 | Kayentis Provider of electronic clinical outcome assessment solutions for clinical trials | $36M | 38 mo ago | Series D | 12 | 2003 | WordPressMySQLPHP+25 | — | 2 job openings · 2 launchs |
| 15 | Mablink Provider of Antibody-Drug-Conjugates (ADC's) technology for cancer treatment | $35M | 44 mo ago | Acquired | 29 | 2018 | — | — | — |
| 16 | Osivax Developer of vaccines against constantly mutating pathogens 32Growth top 28%Funding top 37%Moat top 37%Patents top 40% All 10 signals ▾Growthtop 28% Fundingtop 37% Moattop 37% Patentstop 40% Innovationtop 49% Globalbottom 45% Techbottom 37% Marketbottom 33% Newsbottom 21% Fin. healthbottom 15% Growth: Web rank 50,000,000 → 10,000,000 YoY · Fresh capital in last 24 mo Funding: Raised $31.8M across 8 rounds · 8 rounds over 9 yrs (0.9/yr) rank vs industry peers · Fliar Intelligence Index 32/100 | $32M | 15 mo ago | Series B | 40 | 2017 | WordPressMySQLPHP+24 | 16 patents mRNA and protein-based vaccine formulation and delivery technologies | 1 job opening |
| 17 | Keranova Surgical equipment for anterior chamber Ophthalmic surgery | $31M | 81 mo ago | Series B | 46 | 2015 | WordPressMySQLPHP+18 | 146 patents Ophthalmic laser cutting systems with optical coupling and bubble-energy optimization | — |
| 18 | Remedee Labs Developer of endorphin stimulation therapy for pain management | $28M | 42 mo ago | Series A | 39 | 2016 | WordPressMySQLPHP+21 | 36 patents Wearable millimeter-wave antenna devices for therapeutic and cosmetic electromagnetic treatment | — |
| 19 | Adocia Developer of therapeutics for the treatment of diabetes and obesity 45Product top 14%Patents top 28%Innovation top 35%Funding top 35% All 11 signals ▾Producttop 14% Patentstop 28% Innovationtop 35% Fundingtop 35% Moattop 35% Markettop 49% Growthbottom 47% Techbottom 45% Globalbottom 43% Fin. healthbottom 35% Newsbottom 30% Product: 5 distinct product lines · Company stage: Public Patents: 684 patents matched (strict assignee match) · 119 filings since 2022 vs 272 in 2017-21 rank vs industry peers · Fliar Intelligence Index 45/100 | $26M | 6 mo ago | Public | 111 | 2005 | WordPressApple iCloud MailMicrosoft 365+23 | 684 patents Peptide therapeutics formulation and delivery using polymer conjugates and injectable hydrogels | — |
| 20 | Brenus Pharma Developer of immunotherapy for the treatment of cancer | $25M | 21 mo ago | Series A | 12 | 2020 | WordPressMySQLPHP+12 | — | — |
| 21 | Cytoo Specializes in the development of physiologically-relevant cellular models and assays for High Content… | $16M | 174 mo ago | Series C | 36 | 2008 | WordPressMySQLPHP+21 | 39 patents Therapeutics and AI-driven assays for skeletal muscle hypertrophy and disease diagnostics | — |
| 22 | NH TherAguix Developer of nanoparticle-based theranostic for the treatment of cancer | $16M | 86 mo ago | Series A | 18 | 2015 | — | 94 patents Nanoparticle-based drug delivery and radiopharmaceutical imaging/therapy | — |
| 23 | Surgivisio Imaging and computer-assisted minimally invasive surgery | $14M | 98 mo ago | Series B | 222 | 2009 | — | 44 patents Image-guided surgical navigation and robotic assistance for minimally invasive orthopedic procedures | — |
| 24 | Healshape Developer of products for breast reconstruction and augmentation | $13M | 47 mo ago | Series A | 9 | 2020 | WordPressMySQLPHP+17 | 6 patents 3D-printed medical implants for customized anatomical reconstruction | — |
| 25 | GenOway Provider of transgenic rodent models and customized cell lines for preclinical development | $12M | 77 mo ago | Public | 124 | 1999 | WebflowMatomo AnalyticsGoogle Analytics+16 | 15 patents Genetically engineered animal models with conditional KO/KI and advanced cloning vectors | 1 partnership |
| 26 | NETRI Developer of microfluidic devices for industrial applications | $9M | 16 mo ago | Series A | 45 | 2018 | WordPressMySQLPHP+34 | 33 patents Microfluidic cell‑culture platforms integrating humidification and large‑scale neural activity assays | 2 partnerships |
| 27 | Netris pharma Developer of therapeutic solutions to treat cancer | $8M | 30 mo ago | Series A | 14 | 2008 | WordPressPleskMySQL+20 | 120 patents Patents concentrated in chemistry & materials | — |
| 28 | Tollys Developer of drugs for treating cancer | $7M | 71 mo ago | Series A | 11 | 2015 | — | 10 patents TLR3 agonist immunomodulators for epithelial and myeloid cell activation in therapeutics | — |
| 29 | Fabentech Developing polyclonal antibodies to treat infectious diseases such as avian influenza, ebola etc. | $7M | 42 mo ago | Series A | 54 | 2009 | WordPressMySQLPHP+5 | 6 patents Recombinant antibody production for passive immunotherapy against H5N1 influenza | — |
| 30 | Ciliatech Developer of a implant for treating ophthalmic disorder | $7M | 37 mo ago | Series A | 2 | 2017 | — | 19 patents Ocular interposition implants with surface projections for enhanced fixation and positioning | 1 job opening |
| 31 | Blink Biomedical Antibody-based checkpoint inhibitors for oncology. | $6M | 119 mo ago | Series A | 11 | 2015 | — | 25 patents Therapeutic antibodies for nicotine addiction and CD96-mediated immune modulation | — |
| 32 | 3-D Matrix Developer of synthetic peptides for medical applications | $6M | 18 mo ago | Public | 37 | 2004 | HubSpot CMS HubMaterial Design LiteMicrosoft Clarity+14 | 23 patents Patents concentrated in health & consumer products | — |
| 33 | In2Bones Provider of single use surgical instruments and orthopedic implants for use in lower extremity surgeries. | $6M | 103 mo ago | Acquired | 62 | 2011 | — | 93 patents Orthopedic tibial and ankle joint replacement implants and surgical instrumentation | 1 launch |
| 34 | Signia Therapeutics Re-purposed formulations for influenza infections | $5M | 48 mo ago | Deadpooled | 8 | 2017 | — | 15 patents Repurposed diltiazem-based antiviral combinations for SARS‑CoV‑2 treatment | — |
| 35 | Axess Vision Technology Products for video-Bronchoscopy, video-Ureteroscopy and video-Cystoscopy | $5M | 150 mo ago | Acqui-Hired | 40 | 2006 | — | 138 patents Advanced control and sterilization mechanisms for flexible medical endoscopes. | 1 partnership |
| 36 | ErVimmune Developer of immunotherapies for the treatment of cancer 16News top 36%Moat top 38%Funding top 40%Patents top 44% All 9 signals ▾Newstop 36% Moattop 38% Fundingtop 40% Patentstop 44% Talentbottom 49% Innovationbottom 48% Globalbottom 36% Marketbottom 25% Techbottom 23% News: 3 BI events in 12 mo (of 3 tracked, 1 types) · Top themes: Funding Moat: Editorial + unicorn rating 4/10 · IP moat: 9 patents rank vs industry peers · Fliar Intelligence Index 16/100 | $5M | 4 mo ago | Series A | — | 2019 | WordPressApple iCloud MailMicrosoft 365+16 | 9 patents HERV-based cancer epitope discovery and AML diagnostic/therapeutic biomarkers | 1 job opening |
| 37 | Trixell Manufacturer of X-ray digital detectors imaging plates for radiological imaging industry | $5M | 77 mo ago | Funding Raised | 192 | 1997 | DrupalPHPBootstrap+6 | 320 patents High‑performance matrix detectors for ionizing radiation imaging, especially low‑dark‑current medical scanners. | — |
| 38 | Sublimed Developer of pain management devices | $5M | 89 mo ago | Series A | 22 | 2015 | WordPressMySQLPHP+18 | 2 patents Implantable neurostimulation therapy for chronic knee osteoarthritis pain relief | — |
| 39 | Electroducer Developer of devices for coronary interventions and direct wire pacing | $4M | 59 mo ago | Series A | — | 2018 | — | 37 patents Intravascular catheters for cardiac diagnostics, valve replacement, and autonomic nerve stimulation. | — |
| 40 | NeoMedLight Fiber-optic phototherapy device for neonatal care | $3M | 61 mo ago | Series A | 10 | 2014 | WordPressMySQLPHP+22 | 9 patents Wearable textile phototherapy devices integrating light applicators for targeted skin treatment | — |
| 41 | Allogenica Biotechnology company specializing in the development of allogeneic CAR-T therapies for cancer treatment | $3M | 15 mo ago | Funding Raised | — | 2022 | WixSentryApple iCloud Mail+13 | — | — |
| 42 | Elsalys Biotech Develops therapeutic monoclonal antibodies for cancer and inflammatory diseases | $3M | 65 mo ago | Acqui-Hired | 14 | 2013 | — | 17 patents Immunotherapeutic agents targeting CD160 and TYRO3 receptors for disease treatment | — |
| 43 | Laclarée Developer of an eye-wear solution for presbyopia correction | $2M | 16 mo ago | Seed | 10 | 2016 | WordPressApple iCloud MailMySQL+22 | — | — |
| 44 | Hunt X Pharma Developer of therapeutics for neurological diseases | $2M | 21 mo ago | Seed | — | 2022 | — | — | — |
| 45 | StromaCare Developer of immunotherapy for the treatment of solid tumors | $2M | 48 mo ago | Seed | 9 | 2020 | — | — | — |
| 46 | CTIBiotech Develops 3D human tissue models 19Tech top 45%Talent bottom 49%Funding bottom 47%Global bottom 29% All 5 signals ▾Techtop 45% Talentbottom 49% Fundingbottom 47% Globalbottom 29% Marketbottom 25% Tech: 17 technologies across 5/8 capability areas · Cloud: Amazon Ses, Amazon Web Services Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 19/100 | $1M | 1 mo ago | Funding Raised | — | 2009 | Hostinger Website BuilderNginxOpenResty+14 | — | 2 launchs · 1 partnership · 1 award |
| 47 | Meddenovo Developer of computational biochemistry software for pharmaceutical research and development | $1M | 22 mo ago | Seed | — | 2021 | — | — | — |
| 48 | Smartox Biotechnology Discovery and the synthesis of peptides coming from animal venoms and related drug discovery services | $1M | 32 mo ago | Seed | 14 | 2009 | Cart FunctionalityWooCommerceWordPress+23 | — | — |
| 49 | Nemera Manufacturer of Plastic drug delivery devices for multiple specialties | $849K | 10 mo ago | Acquired | 455 | 2014 | WordPress Block EditorWordPressMySQL+28 | — | 2 launchs |
| 50 | TheraPPI Biotech company developing protein interaction solutions for cancer and related diseases | $113K | 14 mo ago | Seed | — | 2023 | — | — | — |
Top 12 Life Sciences companies in Auvergne Rhone Alpes
#1
Series D · Grenoble, Auvergne Rhone Alpes · founded 2011 · 49 employees$85.7Mraised▾
Developer of active implantable devices for urological incontinence. The device MyoElectroMechanical System is based on a technology where a patient‘s activity is measured in real-time through micro-sensors inside the implant into which algorithms are embedded; the system interprets data coming from the micro-sensors and computes the urethral pressure to apply.
- May 2026Series D$60M
- Jun 2024Series C$47M
- Apr 2021Series B$8.3M
- May 2020Series B$17.5M
#2
Public · Lyon, Auvergne Rhone Alpes · founded 2005 · 111 employees$26Mraised▾
Developer of therapeutics for the treatment of diabetes and obesity. Its proprietary platform called the 'Biochaperone' enhances the effectiveness and safety of therapeutic proteins and enables easier usage on patients. Their clinical pipeline includes a unique formulation of PGDF-BB for the treatment of diabetic foot ulcers and insulin formulations for the treatment of diabetes.
- Dec 2025Post IPO$11.7M
- Feb 2025Post IPO$10.2M
- Oct 2019Conventional Debt$16.5M
- Jan 2010Series B$14M
#3
Series C · Lyon, Auvergne Rhone Alpes · founded 2014 · 34 employees$113.5Mraised▾
Developer of therapeutics for diseases with impaired kidney function. The company offers VONAFEXOR is a small molecule with strong fibrolytic and anti-inflammatory properties in both organs, kidney and liver.
- Jun 2025Series C$6.9M
- Jan 2024Series C$42.8M
- Oct 2018Grant (prize money)$2.8M
- Jun 2018Series B$46.6M
#4
Series A · Lyon, Auvergne Rhone Alpes · founded 2019$4.8Mraised▾
Developer of immunotherapies for the treatment of cancer. The company combines cancer vaccines and T-cell therapies to create treatments based on the identification of new families of tumor antigens.
- Jan 2026Series A$19.8M
- Jun 2023Grant (prize money)$15.4M
- Jan 2023Seed$4.8M
#5
Funding Raised · Lyon, Auvergne Rhone Alpes · founded 2009$1.5Mraised▾
CTIBiotech is a developer of 3D human tissue models for the pharmaceutical industry and dermato-cosmetics sectors. The company also claims of printing cancer tissues in 3D using the tools in bioengineering. It offers 3D tissue and cell models to the pharmaceutical industry for cancer research, regenerative medicine, medical devices, public and private research institutions, and organizations. Offers human biological sample procurement & cell harvesting.
- Apr 2026Grant (prize money)$1.5M
#6
Series B · Lyon, Auvergne Rhone Alpes · founded 2017 · 40 employees$31.8Mraised▾
Developer of vaccines against constantly mutating pathogens. The company leverages oligoDOM a novel proprietary nanoparticles technology specifically designed to trigger superior T-cell responses. The company's lead candidate is OVX836 against influenza and coronavirus.
- Mar 2025Series B$10.5M
- Dec 2023Grant (prize money)—
- Mar 2023Grant (prize money)$1M
- Jun 2022Grant (prize money)$10.5M
#7
Series A · Issoire, Auvergne Rhone Alpes · founded 2020 · 12 employees$25Mraised▾
Developer of immunotherapy for the treatment of cancer. The company's flagship product includes STC-1010 which is used to treat metastatic colorectal cancer (mCRC) and solid cancers.
- Sep 2024Series A$25M
#8
Series A · Lyon, Auvergne Rhone Alpes · founded 2018 · 45 employees$8.9Mraised▾
Developer of microfluidic devices for industrial applications. The company has NeoBento a microfluidic platform that focuses on the development of next-generation 3D brain-on-a-chip models for the treatment of neurological diseases.
- Feb 2025Series A$5.1M
- Mar 2022Series A$8.9M
#9
Acquired · Ecully, Auvergne Rhone Alpes · founded 2015 · 6 employees$292.3Mraised▾
Developer of peptide therapeutics to treat rare endocrine and metabolic disorders. The pipelineincludes two therapeutic peptide programs eneboparatide for the treatment of hypoparathyroidism and AZP-3813 for the treatment of acromegaly.
- Jan 2023Series C$137.5M
- Sep 2021Series B$80M
- Aug 2019Series A$74.8M
#10
Public · Caluire et Cuire, Auvergne Rhone Alpes · founded 2004 · 37 employees$5.9Mraised▾
3-D Matrix develops synthetic peptides for medical applications. The company synthesizes the self-assembling peptide matrix which is composed of three amino acids in a sequence that is repeated 4 times (Arginine - Alanine - Aspartic Acid - Alanine). The company's product includes PuraStat, a self-assembling synthetic peptide scaffold that mimics the human extra cellular matrix (ECM). The product is used in endoscopic, cardiac, and ENT solutions.
- Nov 2024Post IPO$5.7M
- Jan 2021Grant (prize money)$231.9K
#11
Acquired · La Verpilliere, Auvergne Rhone Alpes · founded 2014 · 455 employees$848.9Kraised▾
Nemera is a Manufacturer of Plastic drug delivery devices for multiple specialties. Montagu Private Equity acquired Centor and Nemera from Rexam PLC in a combined transaction in May 2014 through a management buyout. After the acquisition, Montagu renamed the former Rexam prescription retail unit Centor and the Rexam healthcare devices unit. Nemera's products include Ophthalmic (preservative-free multidose eyedroppers), Ear, Nose, Throat (sprays/ pumps, etc.), Inhalation (pMDI, MDIs, DPIs), Dermal and Transdermal (airless & atmospheric dispensers), and Parenteral (auto-injectors, pens, safety devices & implanters) drug delivery devices. Some of its flagship brands are Advancia, Inhalia, Safe’n’Sound and Novelia
- Aug 2025Seed—
- Feb 2017Grant (prize money)$430.6K
- Jan 2017Grant (prize money)$418.3K
#12
Funding Raised · Lyon, Auvergne Rhone Alpes · founded 2022$2.7Mraised▾
Biotechnology company specializing in the development of allogeneic CAR-T therapies for cancer treatment. It uses healthy donor hematopoietic stem cells as the starting material, rather than the patient's own T cells. Company stem cells are bioengineered to express the CAR and then differentiated into immature precursor T cells called CAR-pre-T cells.
- Mar 2025Grant (prize money)$2.7M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Life Sciences coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Biotechnology is moving in France
A read on the academic research around Biotechnology — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,220 France-affiliated papers.
- Centre National de la Recherche Scientifique280
- Inserm169
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement144
- Ministry of Agriculture118
- AgroParisTech36
- Gene3→26
- Genome2→14
- Antibody1→10
- Cell culture1→10
- Mutant1→10
- Gene2→30
- Agriculture1→20
- Selection (genetic algorithm)2→18
- Resistance (ecology)2→16
- Population1→12
- Agriculture2→13
- Antibiotic resistance3→12
- Population1→9
- Public health1→8
- Context (archaeology)2→9
Where biotechnology is researched across France
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing biotechnology patents in France
France biotechnology patent filing is cooling — 34,222 filings from 8,000 assignees (2016–2025), led by Centre NAT RECH Scient, INST NAT Sante RECH MED, Sanofi; annual filings 3501→2745.
- Centre NAT RECH Scient10049
- INST NAT Sante RECH MED8302
- Sanofi3990
- Pasteur Institut3423
- Agronomique INST NAT RECH1334
- Cellectis1320
- PF Medicament1204
- Commissariat Energie Atomique1153