Best Life Sciences Companies in Charlotte, United States
The 38 best Life Sciences companies in Charlotte, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Bardy Diagnostics.
Our analysis of 164 Life Sciences companies
$34.7b in tracked funding; 83% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Life Sciences companies in Charlotte
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Bardy Diagnostics Medical technology company providing solutions for healthcare providers, caregivers, and patients | $83M | 78 mo ago | Acquired | — | 2013 | WordPressMySQLMariaDB+27 | 380 patents Wearable cardiac ECG monitoring devices and remote data/charging infrastructure. | — |
| 2 | Chelsea Therapeutics University of Pennsylvania: Education, research, community, and global impact | $31M | 198 mo ago | Acquired | — | 2004 | — | — | — |
| 3 | SonaCare Medical Minimally-invasive prostate treatment using HIFU technology for precision prostate care | $24M | 109 mo ago | Series B | MARK CAROL CEO & President | 2004 | — | — | — |
| 4 | SoyMeds Biotech research: developing soybean seed-based therapeutics for disease treatment | $6M | 17 mo ago | Funding Raised | — | 2005 | — | 3 patents Plant-based recombinant protein production for oral vaccines using engineered soybeans | — |
| 5 | Amissa Developer of a wearable-based data collection solutions for the prediction, early identification, and… | $5M | 13 mo ago | Funding Raised | Jon Corkey Founder & CEO | 2017 | ContentfulTurbopackNode.js+12 | — | — |
| 6 | Diamond Orthopedic Innovating orthopedic fixation with faceted bone screw technology for enhanced healing | $4M | 105 mo ago | Seed | Roy Bivens CEO | 2016 | — | — | — |
| 7 | OncoTab Blood test for early breast cancer detection in dense breast tissue | $1M | 15 mo ago | Funding Raised | Rahul Puri Co-Founder & CEO | 2011 | — | 5 patents Targeted antibody‑drug conjugates for tumor-specific therapy | — |
| 8 | Adaptin Bio Developer of drug delivery platform for brain diseases | $1M | 8 mo ago | Public | Michael Roberts Co-Founder & CEO | 2023 | — | — | — |
| 9 | Entogenetics Provider of genetically engineered spider silk from silkworms for commercial-scale production | $540K | 157 mo ago | Deadpooled | David Brigham Founder & CEO | 2007 | — | 9 patents Biotechnological production of recombinant spider silk proteins for advanced material applications | — |
| 10 | FullEight Provider of products for sleep and restless leg relief | $115K | 27 mo ago | Seed | Patrick Redmond Founder & CEO | 2020 | — | — | — |
| 11 | Vital Motion Developer of fibromyalgia pain relief device | $100K | 137 mo ago | Deadpooled | Erik Hiester Co-Founder | 2012 | — | — | — |
Top 12 Life Sciences companies in Charlotte
#1
Funding Raised · Charlotte, North Carolina · founded 2017 · 7 employees$4.9Mraised▾
Developer of a wearable-based data collection solutions for the prediction, early identification, and prevention of dementias and other health conditions. The wearable data collection technology enables researchers and clinicians to gather real-world data to improve healthcare outcomes. It monitor compliance and send notifications to ensure adherence, analyse data, and share results.
- Aug 2025Grant (prize money)$2.5M
- Sep 2024Grant (prize money)$505.5K
- Sep 2021Grant (prize money)$1.9M
#2
Public · Charlotte, North Carolina · founded 2023$1Mraised▾
Developer of drug delivery platform for brain diseases. It offers Brain Bispecific T cell Engager hitchhiking drug delivery platform with a ombination of novel T cell engager and specifically manipulated polyclonal T cells for oncology, central nervous system, autoimmune, and cardiovascular diseases.
- Dec 2025Post IPO$1.7M
- Apr 2025Post IPO$7.7M
- Mar 2024Seed$1M
#3
Funding Raised · Charlotte, North Carolina · founded 2005 · 5 employees$6.4Mraised▾
Biotech research: developing soybean seed-based therapeutics for disease treatment. The company focuses on biotechnology research to develop and validate soybean seed-based therapeutics. Their work aims to treat, prevent, cure, and diagnose diseases through innovative applications of soybean technology. They explore commercial applications and technology related to host systems. The company is dedicated to advancing healthcare solutions through plant-based research, contributing to the field of biotechnology with a focus on therapeutic development. This research has a social impact by potentially providing new and accessible treatments for various diseases.
- Apr 2025Grant (prize money)$573.5K
- Jan 2021Grant (prize money)$583.6K
- Sep 2016Grant (prize money)$1M
- Feb 2014Grant (prize money)$541.5K
#4
Funding Raised · Charlotte, North Carolina · founded 2011$1.1Mraised▾
Blood test for early breast cancer detection in dense breast tissue. The company develops innovative diagnostic and therapeutic products focused on cancer, particularly addressing unmet needs in detection and treatment. They utilize cutting-edge, patented technology to target tumor-associated MUC1 (tMUC1), a key cancer antigen. Their lead product, Agkura® Personal Score, is a simple blood test aiding breast cancer detection in women with dense breast tissue, where mammography alone is often insufficient. The company is also developing agents for tumor imaging and targeted drug delivery, aiming to improve cancer outcomes. Their business model centers on research and commercialization through strategic partnerships. This is a B2C and B2B healthcare and diagnostic company.
- May 2025Grant (prize money)$400K
- Sep 2021Grant (prize money)$260.6K
- Sep 2021Grant (prize money)$400K
#5
Acquired · Charlotte, North Carolina · founded 2013 · 229 employees$83.4Mraised▾
Medical technology company providing solutions for healthcare providers, caregivers, and patients. The company focuses on developing and manufacturing a wide range of medical devices and equipment. These include diagnostic cardiology, patient monitoring systems, healthcare furniture, and surgical solutions. The company offers products and services across various healthcare settings, such as hospitals, surgical centers, and home healthcare. The company aims to improve patient outcomes and enhance the efficiency of healthcare delivery through innovative medical technologies. The company provides solutions for vital signs monitoring, safe patient handling, respiratory therapy, and surgical workflow. The company also offers services like remote management, repair, and customer experience centers. The company's products incorporate advanced technologies and connectivity features.
- Feb 2020Series B$12.5M
- Jan 2019Series B$35.5M
- Jul 2018Series B—
- Jun 2018Series B$35.4M
#6
Series B · Charlotte, North Carolina · founded 2004 · 38 employees$24Mraised▾
Minimally-invasive prostate treatment using HIFU technology for precision prostate care. They are focused on transforming sound energy into focused healing, revolutionizing healthcare delivery for patients worldwide. They specialize in focal therapy for prostate disease, offering an alternative to conventional treatments. Their core values include innovation, communication, and customer success. They provide a customizable focal therapy option with robotic accuracy and real-time ultrasound feedback, ensuring patient safety. They are a global leader in HIFU technology, offering a minimally-invasive solution for prostate diseases. They are committed to making a positive impact on patient lives through their innovative technology.
- Aug 2017Conventional Debt$3M
- Jul 2010Series B$1M
- Jul 2009Series B$5M
- 2008Series B$23M
#7
Acquired · Charlotte, North Carolina · founded 2004 · 8 employees$30.7Mraised▾
University of Pennsylvania: Education, research, community, and global impact. It provides access to services and information online while respecting user privacy. The institution collects and uses personal and other information for various purposes, including providing services, fulfilling requests, sending promotional materials, and improving user experience. Data analysis, security measures, and compliance with legal obligations are prioritized. Users have choices regarding their data, and the institution retains information as needed. Third-party services and advertising are utilized. The institution addresses cross-border data transfers and provides contact information for inquiries. It offers online learning, research, innovation, athletics, arts, culture, and community involvement. The website includes login, privacy policy, and resources for students, faculty, staff, parents, alumni, visitors, and media.
- Feb 2010Post IPO$18.2M
- Mar 2007Post IPO$12.5M
#8
Seed · Charlotte, North Carolina · founded 2020$115Kraised▾
Provider of products for sleep and restless leg relief
#9
Seed · Charlotte, North Carolina · founded 2016 · 6 employees$3.5Mraised▾
Innovating orthopedic fixation with faceted bone screw technology for enhanced healing. This company is revolutionizing orthopedic fixation with its patented faceted threadform technology. Their bone screws offer lower insertional torque, increased bone contact, and higher pullout strength, promoting better osteogenesis and device apposition. They focus on advancing orthopedic solutions, providing surgeons with innovative tools for improved patient outcomes. Their products include small bone screw sets, headless compression screw sets, and cannulated screw sets. They are seeking distributors to expand the reach of their innovative product portfolio. They are committed to setting a new fixation standard in orthopedics.
- Nov 2017Seed$3.5M
- Apr 2017Seed$625K
#10
Deadpooled · Charlotte, North Carolina · founded 2007 · 11 employees$540.2Kraised▾
Provider of genetically engineered spider silk from silkworms for commercial-scale production. The company has developed a process for large scale, inexpensive spider silk production from genetically engineered silkworms. EntoGenetics’ technology removes the silk gene from a silkworm and replaces it with spider silk gene. The inserted spider silk gene is then used by the silkworm to make its cocoon.
- Jul 2013Seed$540.2K
#11
Deadpooled · Charlotte, North Carolina · founded 2012 · 6 employees$100Kraised▾
Vital Motion has developed a device for relieving the patient from fibromyalgia pain and symptoms. The Hummingbird is an FDA-registered device used to alleviate aches, pains, fatigue and other symptoms of fibromyalgia. The device applies micro-mechanical stimulation to the nerve-endings in the plantar surface of the foot to activate the soleus muscles in the calves for improving the blood flow throughout the body.
- Apr 2015Seed$100K
#12
Public · Charlotte, North Carolina · founded 1899 · 15000 employees—raised▾
Developer of dental products and equipment. The company's product categories are dental consumable products, dental laboratory products, dental specialty products, and consumable medical device products. The company also manufactures urological catheters and surgical products.
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Life Sciences coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Biotechnology is moving in the United States
A read on the academic research around Biotechnology — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 6,260 United States-affiliated papers.
- Harvard University209
- Cornell University177
- University of Tennessee at Chattanooga140
- Howard Hughes Medical Institute126
- Johns Hopkins University121
- Gene33→164
- Transcription (linguistics)11→79
- Antibody11→62
- Genome6→56
- Mutation7→56
- Gene8→110
- Cell culture3→62
- Gene expression3→62
- Fermentation2→54
- Downregulation and upregulation1→50
- Agriculture19→58
- Antibiotic resistance15→45
- Public health4→31
- Gene6→30
- Production (economics)5→29
Where biotechnology is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing biotechnology patents in the United States
United States biotechnology patent filing is accelerating — 457,918 filings from 8,000 assignees (2016–2025), led by Genentech, UNIV California, Regeneron Pharma; annual filings 36884→44446.
- Genentech18078
- UNIV California17948
- Regeneron Pharma16082
- Amgen10495
- Monsanto Technology9742
- UNIV Pennsylvania8521
- Harvard College7460
- UNIV Texas7378