Best Life Sciences Companies in Lyon, France
The 73 best Life Sciences companies in Lyon, France in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Valneva.
Our analysis of 50 Life Sciences companies
$3.3b in tracked funding; 62% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Life Sciences companies in Lyon
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Valneva Developer of prophylactic vaccines for infectious diseases | $144M | 44 mo ago | Public | Thomas Lingelbach President & CEO | 1999 | WordPressMySQLPHP+24 | 195 patents Viral vaccine production and subunit vaccine formulation for chikungunya and respiratory pathogens | — |
| 2 | Enyo Pharma Developer of therapeutics for diseases with impaired kidney function 60Patents top 20%Innovation top 21%Funding top 25%Moat top 26% All 9 signals ▾Patentstop 20% Innovationtop 21% Fundingtop 25% Moattop 26% Growthtop 45% Techbottom 49% Globalbottom 43% Marketbottom 40% Newsbottom 27% Patents: 164 patents matched (strict assignee match) · 114 filings since 2022 vs 50 in 2017-21 Innovation: 164 patents (top 16% of patent-holders) · 114 filings since 2022 vs 50 in 2017-21 rank vs industry peers · Fliar Intelligence Index 60/100 | $113M | 12 mo ago | Series C | — | 2014 | WordPress Block EditorWordPressMySQL+18 | 164 patents Patents concentrated in health & consumer products | — |
| 3 | Inova Cloud-based biopharma CRM and CRO collaborating system for the life science industry | $71M | 59 mo ago | Series C | David Carteret Co-Founder | 2010 | — | 5 patents Heat‑resistant culinary apparel with elastic closures for improved chef comfort | — |
| 4 | EYE TECH CARE Developer of ultrasound device to treat glaucoma | $52M | 45 mo ago | Series D | — | 2008 | TYPO3 CMSPHPBootstrap+7 | 111 patents Patents concentrated in health & consumer products | — |
| 5 | Poxel Developer of therapeutic solutions for the treatment of Type 2 diabetes | $50M | 46 mo ago | Public | Thomas Kuhn Co-Founder & CEO | 2009 | BootstrapApache HTTP ServerjQuery+7 | 338 patents Deuterated small‑molecule drugs targeting metabolic, neurological and rare genetic disorders. | — |
| 6 | MaaT Pharma Developer of microbiome therapy for the treatment of intestinal dysbiosis diseases | $42M | 59 mo ago | Public | Herve Affagard Founder and Chief Executive Officer | 2014 | WordPressMySQLPHP+25 | 171 patents Patents concentrated in health & consumer products | 1 internship |
| 7 | Mablink Provider of Antibody-Drug-Conjugates (ADC's) technology for cancer treatment | $35M | 44 mo ago | Acquired | Charles Dumontet Co-Founder | 2018 | — | — | — |
| 8 | Osivax Developer of vaccines against constantly mutating pathogens 32Growth top 28%Funding top 37%Moat top 37%Patents top 40% All 10 signals ▾Growthtop 28% Fundingtop 37% Moattop 37% Patentstop 40% Innovationtop 49% Globalbottom 45% Techbottom 37% Marketbottom 33% Newsbottom 21% Fin. healthbottom 15% Growth: Web rank 50,000,000 → 10,000,000 YoY · Fresh capital in last 24 mo Funding: Raised $31.8M across 8 rounds · 8 rounds over 9 yrs (0.9/yr) rank vs industry peers · Fliar Intelligence Index 32/100 | $32M | 15 mo ago | Series B | — | 2017 | WordPressMySQLPHP+24 | 16 patents mRNA and protein-based vaccine formulation and immunogenic composition development | — |
| 9 | Adocia Developer of therapeutics for the treatment of diabetes and obesity 45Product top 14%Patents top 28%Innovation top 35%Funding top 35% All 11 signals ▾Producttop 14% Patentstop 28% Innovationtop 35% Fundingtop 35% Moattop 35% Markettop 49% Growthbottom 47% Techbottom 45% Globalbottom 43% Fin. healthbottom 35% Newsbottom 30% Product: 5 distinct product lines · Company stage: Public Patents: 684 patents matched (strict assignee match) · 119 filings since 2022 vs 272 in 2017-21 rank vs industry peers · Fliar Intelligence Index 45/100 | $26M | 6 mo ago | Public | — | 2005 | WordPressApple iCloud MailMicrosoft 365+23 | 672 patents Patents concentrated in health & consumer products | — |
| 10 | NH TherAguix Developer of nanoparticle-based theranostic for the treatment of cancer | $16M | 86 mo ago | Series A | — | 2015 | — | 94 patents Nanoparticle-based drug delivery and radiopharmaceutical imaging/therapy | — |
| 11 | GenOway Provider of transgenic rodent models and customized cell lines for preclinical development | $12M | 77 mo ago | Public | — | 1999 | WebflowMatomo AnalyticsGoogle Analytics+16 | 15 patents Genetically engineered animal models with conditional KO/KI and advanced cloning vectors | 1 partnership |
| 12 | NETRI Developer of microfluidic devices for industrial applications | $9M | 16 mo ago | Series A | Florian Larramendy CEO - CTO - Co-founder | 2018 | WordPressMySQLPHP+34 | 33 patents Microfluidic cell‑culture platforms integrating humidification and large‑scale neural activity assays | 2 partnerships |
| 13 | Netris pharma Developer of therapeutic solutions to treat cancer | $8M | 30 mo ago | Series A | — | 2008 | WordPressPleskMySQL+20 | 120 patents Patents concentrated in chemistry & materials | — |
| 14 | Tollys Developer of drugs for treating cancer | $7M | 71 mo ago | Series A | Serge Lebecque Co-Founder & CEO | 2015 | — | 10 patents TLR3 agonist immunomodulators for epithelial and myeloid cell activation in therapeutics | — |
| 15 | Fabentech Developing polyclonal antibodies to treat infectious diseases such as avian influenza, ebola etc. | $7M | 42 mo ago | Series A | — | 2009 | WordPressMySQLPHP+5 | 6 patents Recombinant antibody production for passive immunotherapy against H5N1 influenza | — |
| 16 | Blink Biomedical Antibody-based checkpoint inhibitors for oncology. | $6M | 119 mo ago | Series A | Jack Elands Chief Executive Officer | 2015 | — | 25 patents Therapeutic antibodies for nicotine addiction and CD96-mediated immune modulation | — |
| 17 | ErVimmune Developer of immunotherapies for the treatment of cancer 16News top 36%Moat top 38%Funding top 40%Patents top 44% All 9 signals ▾Newstop 36% Moattop 38% Fundingtop 40% Patentstop 44% Talentbottom 49% Innovationbottom 48% Globalbottom 36% Marketbottom 25% Techbottom 23% News: 3 BI events in 12 mo (of 3 tracked, 1 types) · Top themes: Funding Moat: Editorial + unicorn rating 4/10 · IP moat: 9 patents rank vs industry peers · Fliar Intelligence Index 16/100 | $5M | 5 mo ago | Series A | Stephane Depil Founder | 2019 | WordPressApple iCloud MailMicrosoft 365+16 | 9 patents Patents concentrated in chemistry & materials | 1 job opening |
| 18 | Bioxis Developing regenerative medical products in the dermatology and medical aesthetic fields | $3M | 117 mo ago | Series A | Frederic Bertaina Founder & CEO | 2010 | PHPZURB FoundationPrototype+9 | — | — |
| 19 | LXRepair Provider of multiplexed assays for determination of the enzymatic status of cellular DNA repair | $3M | 85 mo ago | Seed | Sylvie Sauvaigo Founder & CEO | 2013 | — | 7 patents DNA repair profiling assays for tumor radiosensitivity and toxicity prediction | — |
| 20 | Allogenica Biotechnology company specializing in the development of allogeneic CAR-T therapies for cancer treatment | $3M | 15 mo ago | Funding Raised | Inna Menkova Co-Founder & CEO | 2022 | WixSentryApple iCloud Mail+13 | — | — |
| 21 | Elsalys Biotech Develops therapeutic monoclonal antibodies for cancer and inflammatory diseases | $3M | 65 mo ago | Acqui-Hired | — | 2013 | — | 17 patents Immunotherapeutic agents targeting CD160 and TYRO3 receptors for disease treatment | — |
| 22 | Laclarée Developer of an eye-wear solution for presbyopia correction | $2M | 16 mo ago | Seed | Bruno Berge Founder & CEO | 2016 | WordPressApple iCloud MailMySQL+22 | — | — |
| 23 | Calixar Specializes in the functional and native isolation of complex therapeutic targets & antigens | $2M | 89 mo ago | Series A | — | 2011 | Webflow EcommerceCart FunctionalityWebflow+16 | 31 patents Patents concentrated in health & consumer products | — |
| 24 | StromaCare Developer of immunotherapy for the treatment of solid tumors | $2M | 48 mo ago | Seed | — | 2020 | — | — | — |
| 25 | CTIBiotech Develops 3D human tissue models 19Tech top 45%Talent bottom 49%Funding bottom 47%Global bottom 29% All 5 signals ▾Techtop 45% Talentbottom 49% Fundingbottom 47% Globalbottom 29% Marketbottom 25% Tech: 17 technologies across 5/8 capability areas · Cloud: Amazon Ses, Amazon Web Services Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 19/100 | $1M | 1 mo ago | Funding Raised | Nico Forraz CEO | 2009 | Hostinger Website BuilderNginxOpenResty+14 | — | 2 launchs · 1 partnership · 1 award |
| 26 | Alma Bio Therapeutics Developer of immunomodulatory drugs for the treatment of autoimmune diseases | $1M | 78 mo ago | Seed | — | 2013 | — | — | — |
| 27 | ETISENSE Developer of a wearable cardio-respiratory monitoring device | $508K | 71 mo ago | Seed | Timothe Flenet Co-Founder & CEO | 2017 | — | 14 patents Wearable inductive plethysmography vests for physiological monitoring of small mammals | 1 partnership |
| 28 | Nova In Silico Developer of AI-driven in silico clinical trial platform for improving decision-making in biology, medicine… | $310K | 129 mo ago | Funding Raised | François-Henri Boissel Co-founder & CEO | 2010 | WordPressMySQLPHP+18 | — | 1 launch |
| 29 | Adjuvatis Developer of biodegradable vaccine adjuvants called i-Particles. | $306K | 103 mo ago | Funding Raised | Charlotte Primard CEO | 2013 | — | — | — |
| 30 | TheraPPI Biotech company developing protein interaction solutions for cancer and related diseases | $113K | 15 mo ago | Seed | Stephane Giraud Co-Founder | 2023 | — | — | — |
| 31 | Imaxio Developer of vaccines against typhoid, cholera, and leptospirosis | $41K | 113 mo ago | Funding Raised | Christian Pradeyrol CEO | 2006 | — | 57 patents Engineered coiled‑coil proteins and influenza nucleoprotein recombinant vaccines | — |
| 32 | Inpart Platform connecting scientific decision makers with research, assets, and expertise | — | 59 mo ago | Seed | Gilles Toulemonde Co-Founder & CEO | 2010 | SanityApple iCloud MailMicrosoft 365+17 | — | — |
Top 12 Life Sciences companies in Lyon
#1
Public · Lyon, Auvergne Rhone Alpes · founded 2005 · 111 employees$26Mraised▾
Developer of therapeutics for the treatment of diabetes and obesity. Its proprietary platform called the 'Biochaperone' enhances the effectiveness and safety of therapeutic proteins and enables easier usage on patients. Their clinical pipeline includes a unique formulation of PGDF-BB for the treatment of diabetic foot ulcers and insulin formulations for the treatment of diabetes.
- Dec 2025Post IPO$11.7M
- Feb 2025Post IPO$10.2M
- Oct 2019Conventional Debt$16.5M
- Jan 2010Series B$14M
#2
Series C · Lyon, Auvergne Rhone Alpes · founded 2014 · 34 employees$113.5Mraised▾
Developer of therapeutics for diseases with impaired kidney function. The company offers VONAFEXOR is a small molecule with strong fibrolytic and anti-inflammatory properties in both organs, kidney and liver.
- Jun 2025Series C$6.9M
- Jan 2024Series C$42.8M
- Oct 2018Grant (prize money)$2.8M
- Jun 2018Series B$46.6M
#3
Series A · Lyon, Auvergne Rhone Alpes · founded 2019$4.8Mraised▾
Developer of immunotherapies for the treatment of cancer. The company combines cancer vaccines and T-cell therapies to create treatments based on the identification of new families of tumor antigens.
- Jan 2026Series A$19.8M
- Jun 2023Grant (prize money)$15.4M
- Jan 2023Seed$4.8M
#4
Funding Raised · Lyon, Auvergne Rhone Alpes · founded 2009$1.5Mraised▾
CTIBiotech is a developer of 3D human tissue models for the pharmaceutical industry and dermato-cosmetics sectors. The company also claims of printing cancer tissues in 3D using the tools in bioengineering. It offers 3D tissue and cell models to the pharmaceutical industry for cancer research, regenerative medicine, medical devices, public and private research institutions, and organizations. Offers human biological sample procurement & cell harvesting.
- Apr 2026Grant (prize money)$1.5M
#5
Series B · Lyon, Auvergne Rhone Alpes · founded 2017 · 40 employees$31.8Mraised▾
Developer of vaccines against constantly mutating pathogens. The company leverages oligoDOM a novel proprietary nanoparticles technology specifically designed to trigger superior T-cell responses. The company's lead candidate is OVX836 against influenza and coronavirus.
- Mar 2025Series B$10.5M
- Dec 2023Grant (prize money)—
- Mar 2023Grant (prize money)$1M
- Jun 2022Grant (prize money)$10.5M
#6
Series A · Lyon, Auvergne Rhone Alpes · founded 2018 · 45 employees$8.9Mraised▾
Developer of microfluidic devices for industrial applications. The company has NeoBento a microfluidic platform that focuses on the development of next-generation 3D brain-on-a-chip models for the treatment of neurological diseases.
- Feb 2025Series A$5.1M
- Mar 2022Series A$8.9M
#7
Funding Raised · Lyon, Auvergne Rhone Alpes · founded 2022$2.7Mraised▾
Biotechnology company specializing in the development of allogeneic CAR-T therapies for cancer treatment. It uses healthy donor hematopoietic stem cells as the starting material, rather than the patient's own T cells. Company stem cells are bioengineered to express the CAR and then differentiated into immature precursor T cells called CAR-pre-T cells.
- Mar 2025Grant (prize money)$2.7M
#8
Seed · Lyon, Auvergne Rhone Alpes · founded 2016 · 10 employees$2.2Mraised▾
Laclaree is the developer of an eye-wear solution for presbyopia correction. The platform has developed the eyeglasses that can be powered with rechargeable batteries and then this electronic hardware is placed in eyeglass frames. Its technology uses a refraction-based solution using liquids that can be inserted in the lense that helps to improve vision.
- Jan 2025Seed$3.6M
- Jan 2025Grant (prize money)$2.6M
- Jun 2020Grant (prize money)$56.2K
- Jan 2020Grant (prize money)$56.1K
#9
Public · Lyon, Auvergne Rhone Alpes · founded 1999 · 719 employees$143.6Mraised▾
Developer of prophylactic vaccines for infectious diseases. The company's lead candidate is VLA1553 is a live-attenuated, single dose vaccine targeting the chikungunya virus. Other products includes VLA15 for Lyme Disease, VLA84 for Clostridium difficile, and VLA1601 for zika virus
- Oct 2022Post IPO$102M
- Jun 2022Post IPO$94.9M
- Feb 2022Grant (prize money)—
- Nov 2021Post IPO—
#10
Public · Lyon, Auvergne Rhone Alpes · founded 2009 · 37 employees$50.4Mraised▾
Developer of therapeutic solutions for the treatment of Type 2 diabetes. It offer products for metabolic diseases with a focus on Type 2 diabetes. Its lead candidate is Imeglimin, an orally active adjunct for diet and exercises to improve glycemic control in patients with type 2 diabetes is a mitochondrial bioenergetics enhancer. Its other products include PXL770, an AMP kinase inhibitor for Type 2 diabetes; PXL007, a FxR agonist for Hepatitis B. Also discovering small molecules targeting GLP-1 receptor, the FXR (farnesoid X receptor) as well as on glucokinase activators and 11-B HSD inhibitor.
- Aug 2022Post IPO$6.1M
- May 2020Post IPO$19.3M
- Jul 2016Post IPO$29.2M
- Jul 2015Post IPO$21.9M
#11
Series D · Lyon, Auvergne Rhone Alpes · founded 2008 · 19 employees$51.6Mraised▾
EYE TECH CARE has developed a CE and CFDA approved ultrasound device. The flagship product, EyeOP1 offers a non-invasive treatment for refractory glaucoma. The procedure is performed under local anesthesia. The device is positioned on the patient's eye and the transducer delivers ultrasound energy to reduce intraocular pressure.
- Sep 2022Series D—
- Jan 2016Series D$27.3M
- Mar 2013Series C$13M
- Jul 2010Series B$9.4M
#12
Acquired · Lyon, Auvergne Rhone Alpes · founded 2018 · 29 employees$35Mraised▾
Provider of Antibody-Drug-Conjugates (ADC's) technology for cancer treatment. It offers its propriety hydrophilic linker platform and Mablink’s approach for developing the drug. It forms a non-polymeric of MW 2.0 kD linker which is plasma-stable homogeneous ADCs and doesn't require a site-specific conjugation to binds. The products include MBK-101, MBK-102 for Acute myeloid leukemia, and Multiple myeloma.
- Oct 2022Series A$30.2M
- Apr 2021Seed$4.8M
- 2018Grant (prize money)$1.7M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Life Sciences coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Biotechnology in Lyon is moving
A read on the academic research around Biotechnology in Lyon — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 41 papers.
- Université Claude Bernard Lyon 114
- Ecologie Microbienne Lyon10
- Hospices Civils de Lyon5
- Institut National des Sciences Appliquées de Lyon4
- École Normale Supérieure de Lyon3
- Ribozyme2
- Polymerase2
- Ligase ribozyme2
- RNA polymerase I2
- RNA polymerase2
- Antimicrobial2
- Genome2
- Essential oil1
- Antibacterial activity1
- Vanillin1
- Antibiotics2
- Antibiotic resistance2
- Antibody2
- Microbiome1
- Microbiology1