Best Life Sciences Companies in Minneapolis, United States
The 121 best Life Sciences companies in Minneapolis, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: CVRx.
Our analysis of 164 Life Sciences companies
$34.7b in tracked funding; 83% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Life Sciences companies in Minneapolis
| # | Company | Disclosed funding | Last round | Stage | Employees | Founded | Founder | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | CVRx Developer of implantable technology for hypertension and heart failure | $394M | 71 mo ago | Public | 142 142 → 252 (+77%) | 2001 | — | 284 patents Implantable baroreflex activation devices and minimally invasive electrode delivery systems | 1 partnership |
| 2 | Nuvaira Provider of a catheter-based system for patients suffering from COPD 57Funding top 18%Moat top 23%Product top 31%Patents top 33% All 11 signals ▾Fundingtop 18% Moattop 23% Producttop 31% Patentstop 33% Innovationtop 35% Growthtop 40% Talentbottom 49% Marketbottom 46% Techbottom 46% Globalbottom 40% Newsbottom 27% Funding: Raised $191M across 10 rounds · 10 rounds over 17 yrs (0.6/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 97 patents rank vs industry peers · Fliar Intelligence Index 57/100 | $191M | 3 mo ago | Series E | 57 | 2008 | Dennis Wahr CEO | 97 patents Minimally invasive therapeutic devices for respiratory, esophageal and catheter-based interventions | 1 job opening |
| 3 | Flywheel Cloud based data research platform 80Funding top 14%AI top 20%Product top 21%Moat top 31% All 10 signals ▾Fundingtop 14% AItop 20% Producttop 21% Moattop 31% Innovationtop 32% Techtop 33% Growthtop 35% Talenttop 38% Marketbottom 49% Globalbottom 39% Funding: Raised $110M across 10 rounds · 10 rounds over 8 yrs (1.2/yr) AI: Classified as an AI company rank vs industry peers · Fliar Intelligence Index 80/100 | $110M | 5 mo ago | Series D | 160 | 2015 | Gunnar Schaefer Co-Founder | — | 1 partnership |
| 4 | ShiraTronics Developer of a neuromodulating device for treating migraine | $108M | 21 mo ago | Series B | 29 | 2019 | — | 67 patents Implantable neurostimulation devices for headache relief with wireless charging and communication | — |
| 5 | Torax Medical Products to restore human sphincter function | $103M | 118 mo ago | Acqui-Hired | 70 | 2002 | — | — | — |
| 6 | Kips Bay Medical Medical device company innovating vascular technologies for cardiac surgeons | $63M | 134 mo ago | Public | 13 | 2007 | — | — | — |
| 7 | Rotation Medical Device for rotator cuff disease | $55M | 118 mo ago | Acquired | 34 | 2009 | — | 280 patents Minimally invasive delivery and fixation of implantable sheets and tendon repair devices | — |
| 8 | Amphora Medical Radiofrequency ablation device for overactive bladder treatment | $48M | 106 mo ago | Series B | 12 | 2011 | — | — | — |
| 9 | KORONIS BIOMEDICAL TECHNOLOGIES Developer of sensors for diagnosis of lung diseases | $40M | 9 mo ago | Funding Raised | — | 2003 | — | — | — |
| 10 | FOXO Technologies Provider of epigenetic biomarkers discovery and development platform | $40M | 12 mo ago | Public | 15 | 2020 | — | 3 patents Machine‑learning analysis and quality control of epigenetic DNA data for health diagnostics | — |
| 11 | Lutonix Global medical technology company advancing healthcare through innovative solutions and services | $35M | 186 mo ago | Acquired | 9 | 2007 | Lixiao Wang Co-Founder & CTO | 162 patents Patents concentrated in health & consumer products | — |
| 12 | Velocimed Interventional cardiology devices | $34M | 260 mo ago | Acquired | — | 2001 | Dennis Wahr Founder & CEO | 6 patents Medical closure devices and delivery tools for fluid containers | — |
| 13 | iVEAcare Developer of neuromodulation technology intended to treat patients suffering from chronic diseases | $28M | 25 mo ago | Series A | — | 2023 | Mudit Jain Co-Founder | 5 patents Personalized vagus nerve stimulation and AI-driven seizure/depression monitoring | — |
| 14 | Eon Aligner Provider of invisible and removable braces | $26M | 55 mo ago | Series B | 216 | 2008 | Firas Shahrour Co-Founder | — | — |
| 15 | Tactile Medical Provider of lymphedema and venous ulcer treatment therapy and pumps | $23M | 164 mo ago | Public | 592 592 → 1,106 (+87%) | 1995 | — | — | 1 internship · 1 partnership · 1 award |
| 16 | VDyne Developer of a medical device to treat tricuspid regurgitation | $21M | 65 mo ago | Series C | — | 1992 | Edward Malouf CEO | 178 patents Transcatheter heart valve delivery systems with side‑entry and cinching mechanisms | — |
| 17 | RxFunction Provider of wearable prosthesis for people with sensory peripheral neuropathy | $19M | 43 mo ago | Series B | 30 | 2010 | Lars Oddsson CTO & Co-Founder | 26 patents Sensory nerve stimulation and feedback systems for gait and balance enhancement | 5 job openings · 1 award |
| 18 | Preceptis Medical Surgical tool for ear tube procedures | $19M | 2 mo ago | Series B | 4 | 2011 | — | — | — |
| 19 | Hyloris Developer of drugs for rare and orphan disease conditions | $16M | 73 mo ago | Public | 14 | 2014 | Stijn Rompay CEO | — | 1 expansion |
| 20 | Celcuity Developer of targeted therapies for cancer patients | $15M | 32 mo ago | Public | 42 | 2012 | — | 74 patents Predictive biomarker assays and companion diagnostics for PI3K/mTOR cancer therapies | — |
| 21 | Humanetics Corporation Clinical-stage biopharma company developing radiation modulators as therapeutics for solid cancers | $13M | 31 mo ago | Funding Raised | 4 | 1988 | Ronald Zenk Chief Executive Officer and member of the Board of Directors | 99 patents Pharmaceutical genistein formulations for inflammatory/respiratory disorders and radiation sensitizers. | — |
| 22 | Vascular Solutions Products for vascular diagnostics and interventional procedures | $12M | 196 mo ago | Acquired | 562 | 1997 | — | 85 patents Minimally invasive vascular closure, occlusion, and guidewire technologies for endovascular procedures. | — |
| 23 | InterValve Aortic valvuloplasty balloon catheter | $11M | 136 mo ago | Acquired | 15 | 2008 | — | 35 patents Catheter-based heart valve repair and measurement devices for mitral and aortic interventions | — |
| 24 | GT Urological Domain name sales and pricing services with expert support | $11M | 142 mo ago | Deadpooled | 4 | 2002 | — | 66 patents Hydraulic occlusion devices for urethral and vascular treatment and their packaging. | — |
| 25 | Altheus Therapeutics Developing therapies for the treatment of inflammatory bowel disease | $10M | 148 mo ago | Deadpooled | — | 2006 | Dennis Schafer CEO | — | — |
| 26 | Given Imaging Global healthcare technology company alleviating pain, restoring health, extending life | $10M | 238 mo ago | Acquired | 804 | 1998 | — | 51 patents Capsule-based gastrointestinal imaging and magnetically steerable ingestible endoscopic devices | — |
| 27 | Aspire Beverages Functional beverage company commercializing low-calorie sports drink products | $10M | 128 mo ago | Deadpooled | — | 2012 | Jesse Parker Co-Founder & CEO | — | — |
| 28 | Sterilucent Manufacturer of Hydroxen Peroxide sterilizers | $8M | 134 mo ago | Series A | 17 | 2004 | David Bell Founder | 52 patents Advanced diffusion-based sterilization and drying systems for medical devices and instruments | — |
| 29 | Pops Diabetes Provides smart devices and app-based solution for managing diabetes | $8M | 84 mo ago | Series A | 25 | 2013 | Dan Davis Co-Founder | 39 patents Remote glucose monitoring and telehealth analytics for diabetes management | — |
| 30 | Travanti Pharma Speciality biopharma company that develops and markets drug delivery platforms | $8M | 238 mo ago | Acqui-Hired | — | 1997 | Paul Mori CEO | — | — |
| 31 | Bio-Techne Developer of biotech reagents, instruments and clinical diagnostic products | $5M | 120 mo ago | Public | 2,400 2,400 → 2,975 (+24%) | 1981 | — | — | 1 internship · 1 partnership |
| 32 | Orasi Medical Provider of imaging software to diagnose and monitor neurological diseases | $5M | 187 mo ago | Deadpooled | — | 2007 | Mark T. Wagner CEO | — | — |
| 33 | UroDev Medical Developer of the bladder management device | $5M | 97 mo ago | Seed | 14 | 2015 | — | — | — |
| 34 | SpineThera Developer of therapeutics for chronic pain management | $5M | 60 mo ago | Funding Raised | — | 2012 | Jeff Missling Chief Executive Officer | 27 patents Peptide-based pharmaceutical formulations using salts and surfactants | — |
| 35 | Gila Therapeutics Developer of therapeutics for the treatment of obesity and cardiometabolic disorders | $5M | 30 mo ago | Series A | 1 | 2014 | Andres Acosta Co-Founder | — | — |
| 36 | Discovery Genomics Gene therapies for blood diseases | $4M | 184 mo ago | Acquired | 6 | 2000 | — | — | — |
| 37 | Pelvital Innovative mechanotherapy device for treating stress urinary incontinence and strengthening pelvic floor | $4M | 37 mo ago | Series A | — | 2016 | Ole Olsen Co-Founder | — | — |
| 38 | Luminary Developer of cell therapies for treating cancer | $3M | 8 mo ago | Series B | 8 | 2019 | — | 6 patents Patents concentrated in health & consumer products | — |
| 39 | NitriCap Medical Developer of single-use antimicrobial catheter insert device | $3M | 62 mo ago | Series A | 2 | 2020 | — | — | — |
| 40 | Be The Match Provider of cell therapy research, patient support, and donor registry | $3M | 10 mo ago | Funding Raised | 2,281 | 1987 | — | 126 patents AI-driven social networking recommendation and remote conversation facilitation platforms | — |
| 41 | Crossfire Medical Developer of medical devices for chronic venous insufficiency | $3M | 53 mo ago | Seed | 9 | 2016 | Scott Nelson Co-Founder | — | — |
| 42 | Surgical Information Sciences AI and cloud-based platform for visualizing brain MRI images | $3M | 79 mo ago | Seed | — | 2012 | Guillermo Sapiro Co-Founder | — | — |
| 43 | R&D Systems Developer of reagents and kits for biotech research and development | $2M | 94 mo ago | Funding Raised | 788 | 1985 | — | 1,296 patents Advanced multi‑plane stereolithography materials and high‑resolution 3D printing processes | 3 launchs |
| 44 | CloSys Corporation Vascular closure device using natural clotting for closure | $2M | 120 mo ago | Series A | — | 2005 | Karol Nowakowski Founder and CTO | 14 patents Hemostatic wound closure devices employing clotting cascade activation | — |
| 45 | OneOme Pharmacogenomic testing for personalized prescriptions, co-developed with Mayo Clinic | $2M | 108 mo ago | Seed | 45 | 2014 | Troy Kopischke Co-Founder & CEO | 3 patents Pharmacogenomic decision-support engines for genotype-based drug stratification | — |
| 46 | Sora Neuroscience Developer of brain mapping software utilizing resting state functional MRI | $1M | 32 mo ago | Seed | 3 | 2020 | — | — | — |
| 47 | Photonic Pharma Pioneering precision in early-phase drug discovery with advanced biosensor technology | $1M | 50 mo ago | Funding Raised | 11 | 2014 | Jennifer Thomas Co-Founder | — | — |
| 48 | Delve Health Digital clinical trial management tool for researchers | $1M | 47 mo ago | Seed | 14 | 2015 | — | — | — |
| 49 | Neuroglide Developer of automated lymphatic drainage therapy for pain relief and lymphatic health | $852K | 13 mo ago | Seed | — | 2016 | Irene Waldridge Founder & CEO & CTO | — | — |
| 50 | AcQumen Medical Developer of hemodynamic monitor providing continuous cardiac output for pediatric patients | $341K | 7 mo ago | Seed | — | 2024 | Rodney Houfburg Co-Founder & CTO | — | 1 award |
Top 12 Life Sciences companies in Minneapolis
#1
Series E · Minneapolis, Minnesota · founded 2008 · 57 employees$191.1Mraised▾
Provider of a catheter-based system for patients suffering from COPD. The company is developing Nuvaira Lung Denervation System, a catheter-based system used to treat the overactive airway nerves in a procedure called Targeted Lung Denervation (TLD). It provides an ablative therapy that opens obstructed airways to improve breathing.
- Feb 2026Series E$35.8M
- Nov 2023Series E$15.1M
- Jan 2022Series E$31.3M
- Feb 2019Series E$79M
#2
Series D · Minneapolis, Minnesota · founded 2015 · 160 employees$110Mraised▾
Cloud based data research platform. It is a data research platform provider for the healthcare industry. It provides a platform for data capture, analysis, and research sharing. It also provides a platform for researchers to help in data capture, analysis, and research sharing. It allows data migration for importing data into its systems and combining data from multiple data sets.
- Dec 2025Series D$27.5M
- Oct 2025Series D$2.3M
- May 2025Grant (prize money)$8.7M
- Dec 2024Series D$20M
#3
Series B · Minneapolis, Minnesota · founded 2011 · 4 employees$19.2Mraised▾
Preceptis Medical is a medical device manufacturer developing surgical tools that allow ear tube procedures to be performed with reduced pain and surgical time for the pediatric patient. Its product, The HUMMINGBIRD TTS Tympanostomy Tube System, gives physicians the option to perform the procedure using moderate or conscious sedation. The device is not commercially available. Participated with Mayo Clinic and Children’s Hospitals and Clinics of Minnesota clinical study.
- Apr 2026Series B$2.6M
- Dec 2020Series B$3.2M
- Mar 2020Series B$3.7M
- Jun 2018Series B$6M
#4
Funding Raised · Minneapolis, Minnesota · founded 2003$40.2Mraised▾
Developer of sensors for diagnosis of lung diseases
- Aug 2025Grant (prize money)$389K
- Aug 2025Grant (prize money)$1.9M
- 2024Grant (prize money)$1M
- 2021Grant (prize money)$3.4M
#5
Public · Minneapolis, Minnesota · founded 2020 · 15 employees$40Mraised▾
Provider of epigenetic biomarkers discovery and development platform. The company leverages advanced machine learning and artificial intelligence to analyze complex data, particularly in the field of epigenetic biomarker research related to human longevity. It applies AI to DNA methylation to identify molecular biomarkers of human health and aging, revolutionizing underwriting and mortality prediction in the insurance industry.
- Jun 2025Post IPO$1.6M
- May 2025Post IPO$1.1M
- Apr 2025Post IPO$600K
- Dec 2024Post IPO$110K
#6
Series B · Minneapolis, Minnesota · founded 2019 · 29 employees$107.7Mraised▾
ShiraTronics (a spinout from NuXcel) is a developer of neuromodulation devices for treating migraines. The company claims that the implant uses neuromodulation technologies to treat migraine and other chronic diseases. Some of the partners are AMZAK, APERTURE, and LivaNova.
- Sep 2024Series B$66M
- Aug 2023Series A$8.7M
- Nov 2019Series A$33M
#7
Series B · Minneapolis, Minnesota · founded 2019 · 8 employees$3.4Mraised▾
Developer of gene therapies for treating cancer. The company has developed a allogenic platform that utilizes gamma technology to develop a pipeline consists of two products LMY-920 for B-cell malignancies and autoimmune disorders, LMY-232 for solid tumors and autoimmune disorders.
- Oct 2025Series B$1.4M
- Apr 2025Grant (prize money)$3.7M
- Feb 2025Grant (prize money)$399.3K
- Jan 2025Grant (prize money)$3.7M
#8
Funding Raised · Minneapolis, Minnesota · founded 1987 · 2281 employees$3Mraised▾
Provider of cell therapy research, patient support, and donor registry. They facilitate connections between researchers and supporters to accelerate innovation in finding cures. They maintain a registry of potential donors and work with transplant partners to expand access to treatment. The organization offers physical, emotional, spiritual, and financial support to patients and caregivers.
- Aug 2025Grant (prize money)$2.1M
- Aug 2007Grant (prize money)$882.9K
#9
Seed · Minneapolis, Minnesota · founded 2024$341.4Kraised▾
Developer of hemodynamic monitor providing continuous cardiac output for pediatric patients. The monitor utilizes ultrasound and impedance technology for noninvasive and accurate measurements. It empowers healthcare providers with clinically relevant measurements and data analytics.
- Oct 2025Conventional Debt—
- Oct 2025Seed$341.4K
#10
Seed · Minneapolis, Minnesota · founded 2016$852.1Kraised▾
Developer of automated lymphatic drainage therapy for pain relief and lymphatic health. It offers Neuroglide that simulates and automates manual lymphatic drainage (MLD) therapy and myofascial manipulation (MM) to bring about pain relief and reduce inflammation.
- Apr 2025Seed$50K
- Aug 2024Seed$50K
- Oct 2022Seed$80.1K
- Mar 2020Seed$25K
#11
Public · Minneapolis, Minnesota · founded 2001 · 142 employees$394.1Mraised▾
CVRx is a developer of implantable technology for hypertension and heart failure. The product Barostim neo is implanted under the skin, similar to a pacemaker. It then sends signals to the body's cardiovascular regulators to improve cardiac and vascular function by restoring sympathovagal balance through activation of the afferent and efferent pathways of the autonomic nervous system. The product is CE marked and approved for sale in Europe for both indications.
- Jul 2020Series F$50M
- May 2019Series F$75.4M
- Aug 2016Conventional Debt$20M
- Sep 2014Venture Debt$15M
#12
Series A · Minneapolis, Minnesota · founded 2023$27.5Mraised▾
Developer of neuromodulation technology intended to treat patients suffering from chronic diseases. It offer devices and software that deliver targeted electrical stimulation to specific areas of the brain or spinal cord enabling medical professionals to create therapies.
- Apr 2024Series A$27.5M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Life Sciences coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Biotechnology is moving in the United States
A read on the academic research around Biotechnology — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 6,260 United States-affiliated papers.
- Harvard University209
- Cornell University177
- University of Tennessee at Chattanooga140
- Howard Hughes Medical Institute126
- Johns Hopkins University121
- Gene33→164
- Transcription (linguistics)11→79
- Antibody11→62
- Genome6→56
- Mutation7→56
- Gene8→110
- Cell culture3→62
- Gene expression3→62
- Fermentation2→54
- Downregulation and upregulation1→50
- Agriculture19→58
- Antibiotic resistance15→45
- Public health4→31
- Gene6→30
- Production (economics)5→29
Where biotechnology is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing biotechnology patents in the United States
United States biotechnology patent filing is accelerating — 457,918 filings from 8,000 assignees (2016–2025), led by Genentech, UNIV California, Regeneron Pharma; annual filings 36884→44446.
- Genentech18078
- UNIV California17948
- Regeneron Pharma16082
- Amgen10495
- Monsanto Technology9742
- UNIV Pennsylvania8521
- Harvard College7460
- UNIV Texas7378