Best Life Sciences Companies in Misgav, Israel

Escala Medical is focussed on developing a device for the treatment of pelvic organ prolapse (POP). It has developed a device whose approach mirrors the surgery-based repair to fix the vaginal apex to the sacrospinous ligament (SSL). As of September 2016, the device is in technological development and claims to be a nonsurgical, incision-free, mesh-free repair approach.

Vessi Medical develops a method for treating Non-Muscle Invasive Bladder Cancer (NMIBC). The company uses surface cryotherapy, a method that utilizes extreme cold, to freeze and destroy abnormal tissue. The invasive solution for NMIBC provides a new, first-line, therapeutic alternative to surgery

Developer of a repair system for meniscus tears of the knee. It uses proprietary SuperBall repair system that has developed a knotless all-suture implant and a delivery system for meniscus repair. The system preserves meniscus functionality, repairs hard-to-reach areas, provides full meniscus coverage and is easy to operate.

Developer of immunotherapies for oncology and autoimmune diseases. The lead candidate BND 22 is an immune checkpoint inhibitor for solid tumors, BION-206 is a VHH antibody, enhances phagocytosis, and BND-35 is an antibody targeting ILT3 receptor for the treatment of solid tumors. The INspire technology is a platform for the internalization of antibodies into cells, addressing “undruggable” intracellular targets.

Developer of minimally invasive BPH treatment solutions. It offers a non-surgical procedure to restore urinary function and relieve symptoms associated with benign prostatic hyperplasia (BPH). The solution provides long-term efficacy with reduced risk, preserving sexual function and eliminating complications associated with traditional treatments. The procedure is minimally invasive, reversible, and offers immediate relief. The technology utilizes a unique tissue-embedding technique to maintain a clear urethral pathway.

MitrAssist is a medical devices company in the cardiology field. It aims to provide a minimally invasive solution for the treatment of mitral regurgitation (MR). The proprietary valve implant is neither repair nor replacement, instead, it is placed on top of the natural valve to work in unison with it and to enhance valve functionality.

Gordian Surgical is developing a trocar with an integrated closure system that provides a suture-anchored fascia closure for improved laparoscopic procedures. Their two-in-one trocar can be adapted to different types of trocars including bladed/bladeless, disposable/multiuse, and others

ElastiMed is developing a wearable compression device, to improve blood circulation in the lower extremity by mimicking rhythmic calf muscle contractions and stimulating blood flow. The compression stocking has applications in the treatment of treatment of CVI (Chronic Venous Insufficiency), Lymphedema and prevention of DVT (Deep Vein Thrombosis). Based on proprietary technology utilizing smart materials, ElastiMed’s stocking stretches and contracts when stimulated by an electric pulse (generated by a 3V battery). The company claims that these unique capabilities combined with low-cost materials and a high level of control, enables the ElastiMed stocking to provide patients with a highly effective and easy-to-wear, affordable treatment option. The products are targeted at the compression therapy market, which was estimated at $2.2B worldwide in 2014. The company is backed by Trendlines, an Israel-based innovation commercialization company.

OrthoSpin is focussed on developing a smart external fixation system for bone injuries, bone lengthening & limb deformities. It has developed a hexapod-shaped external frame system that stabilizes broken bones until healing occurs. The system automatically and continuously adjusts and lengthens the struts according to the prescribed treatment regimen. It also developed a proprietary software program which allows physicians to chart patient progress and to change the treatment schedule.

Provider of an enteral feeding device for the treatment of gastrointestinal disorders. The company product includes a PEG device disposable feeding tube with an internal bumper that enables to prevent dislodgment and breaks apart for trauma.

Provider of miniature screwless spine fusion implant. The company offers zLOCK SI to treat SI dysfunction, zLOCK Cervical is used to stabilize and treat spinal stenosis, zLOCK lumbar is used to treat spinal stenosis and facet arthritis.

Founders & team

Ofer LevyCEO

Investors

MassChallenge, The Trendlines Group, Israel Innovation Authority, Europa, EIC Fund

Tech stack

WixReactGoogle CloudSectigoHstsGoogle Cloud Cdn

ApiFix offers an "internal brace” to correct the spinal curve and maintain it. The ApiFix Internal Brace System is attached to the spine via 2 pedicle screws in an hour long procedure. The expandable rod between the two screws uses a miniature ratchet mechanism that captures incremental deformity corrections at the time of patient is performs side bending exercises to the corrective direction, at home, for 6 months after the operation.The long, incremental process reduces the load on the screws and allows the body to rebuild itself in the correct position. Product is CE Marked.