Best Life Sciences Companies in Raleigh, United States
The 87 best Life Sciences companies in Raleigh, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Sprout Pharmaceuticals.
Our analysis of 164 Life Sciences companies
$34.7b in tracked funding; 83% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Life Sciences companies in Raleigh
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Sprout Pharmaceuticals Developer of drugs for hypoactive sexual desire disorder in women | $175M | 18 mo ago | 31 | 2011 | — | Cart FunctionalitySquarespace CommerceSquarespace+15 | — | — |
| 2 | Micell Drug eluting coronary stent | $158M | 105 mo ago | 2 | 1995 | — | — | 363 patents Controlled-release polymer coatings for drug-eluting, bioabsorbable medical implants and devices | — |
| 3 | Slate Medicines Developer of therapeutics for the treatment of migraine and other headache disorders 53Funding top 20%Talent bottom 49%Global bottom 48% All 3 signals ▾Fundingtop 20% Talentbottom 49% Globalbottom 48% Funding: Raised $130M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 53/100 | $130M | 4 mo ago | — | 2026 | Neil Buckley Co-Founder & CEO | — | — | — |
| 4 | Bryn Pharma Developer of nasal based epinephrine for anaphylaxis 10Funding top 26%Talent bottom 49%Global bottom 29%News bottom 24% All 6 signals ▾Fundingtop 26% Talentbottom 49% Globalbottom 29% Newsbottom 24% Marketbottom 20% Techbottom 17% Funding: Raised $123M across 6 rounds · 6 rounds over 8 yrs (0.8/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 10/100 | $123M | 14 mo ago | 10 | 2018 | David Dworaczyk Retired CEO: Corporate Advisor/Consultant to Bryn Pharma | PleskWindows ServerMicrosoft ASP.NET+10 | — | — |
| 5 | Locus Biosciences Developer of therapeutics for infectious disease and inflammatory indications | $67M | 28 mo ago | 74 74 → 61 (-18%) | 2015 | Paul Garofolo Chief Executive Officer | WordPress Block EditorWordPressMySQL+24 | 60 patents Engineered CRISPR‑enhanced bacteriophage therapeutics targeting antibiotic‑resistant bacterial infections | — |
| 6 | Contego Medical Provider of vascular stenting with embolic protection for both coronary and peripheral vasculature | $66M | 38 mo ago | 33 | 2005 | — | — | — | — |
| 7 | Ribometrix Provider RNA-targeted drug discovery platform | $65M | 80 mo ago | 26 | 2016 | — | — | 9 patents eIF4E inhibitor small molecules for oncology therapeutics | — |
| 8 | BioDelivery Sciences International Specialty pharmaceutical solutions for pain management and addiction | $40M | 84 mo ago | 188 | 1997 | Jeffrey Bailey CEO | — | 204 patents Mucoadhesive, abuse‑resistant transmucosal drug delivery systems for opioids and pain therapeutics. | — |
| 9 | Valencell Developer of based medical sensors for monitoring body vitals | $38M | 76 mo ago | 34 | 2006 | Steven Leboeuf President & Co-Founder | Tailwind CSSVue.jsAstro+13 | 418 patents Wearable photoplethysmography sensors for real-time health metrics estimation | — |
| 10 | Aer Therapeutics Developing an inhaled approach to treat lung disease with excess mucus and mucus plugs | $36M | 16 mo ago | 8 | 2014 | John Fahy Founder | — | — | — |
| 11 | Marius Pharmaceuticals Developer of an proprietary oral testosterone replacement therapy platform | $33M | 56 mo ago | 20 | 2017 | Himanshu Shah Co-Founder | WordPressMySQLPHP+17 | — | 1 partnership |
| 12 | Glycan Therapeutics Developer of glycan-based therapeutics for coagulation and thrombo inflammation | $23M | 14 mo ago | 4 | 2013 | Yongmei Xu Co-Founder
| TypeScriptBootstrapZone.js+9 | — | — |
| 13 | 9 Meters Biopharma Developer of drug compounds to treat short bowel syndrome and celiac disease | $23M | 73 mo ago | 21 | 2012 | — | WordPress Block EditorWordPressMySQL+37 | 43 patents Therapeutics targeting intestinal tight junctions and barrier permeability for GI disorders. | — |
| 14 | Midatech Developer of therapies focused on oncology treatment and oncology supportive care | $17M | 148 mo ago | — | 2003 | Christopher Clement President and CEO | — | 23 patents Nanoparticle-based peptide drug and vaccine delivery systems for targeted therapeutic administration | — |
| 15 | Clinverse Cloud-based financial lifecycle system for automating clinical payments for the clinical trials industry. | $16M | 142 mo ago | 51 | 2008 | — | — | 4 patents Healthcare payment network for clinical services and billing integration | — |
| 16 | NuPulseCV Transforming chronic heart failure treatment with minimally invasive cardiac assist devices | $14M | 59 mo ago | 23 23 → 20 (-13%) | 2011 | Douglas Altschuler Founder & CEO | — | 81 patents Percutaneous mechanical circulatory support devices and real-time cardiac rhythm monitoring | — |
| 17 | TranS1 Medical device company delivering innovative spine surgery solutions | $12M | 277 mo ago | 32 | 2002 | — | — | 207 patents Spinal minimally invasive surgical tools, implants, and therapeutic devices for vertebral fixation and motion preservation. | — |
| 18 | Clinetic Provider of data analysis and diagnostic tools for clinical trial professionals | $11M | 34 mo ago | 17 | 2017 | Erich Huang Md Founder | — | — | — |
| 19 | Advanced Chemotherapy Technologies Developer of a medical device used for chemotherapy | $8M | 58 mo ago | 12 | 2014 | — | — | — | — |
| 20 | Gentris A provider of pharmacogenomic testing and biorepository services | $6M | 253 mo ago | 40 | 2001 | — | — | 2 patents Generating reference controls for pharmacogenomic testing | — |
| 21 | Altopa Provider of personalized supplements based on a quiz | $5M | 89 mo ago | — | 2016 | Matt Wilson Co-Founder | — | 28 patents Microfluidic precision dispensing and on-demand mixing for personalized formulation delivery | — |
| 22 | EternaTear Developer of medicine for dry eye disease | $5M | 69 mo ago | 2 | 2018 | Tim Willis Founder & CEO | — | 17 patents Eye‑drop pharmaceutical compositions for treating ocular surface disorders. | — |
| 23 | NephroGenex Innovator developing drugs for kidney disease, particularly diabetic nephropathy | $4M | 127 mo ago | 6 | 2004 | — | — | 22 patents Pyridoxamine-based inhibitors targeting advanced glycation end‑products for diabetic nephropathy therapy | — |
| 24 | SelSym Developer of therapeutics for hemostasis and wound healing | $3M | 9 mo ago | 5 | 2019 | — | — | — | — |
| 25 | Bedrock Therapeutics Developer of gene therapy using AAV capsids and immune modulators | $2M | 15 mo ago | — | 2019 | Bedrock Inc Owner | — | — | — |
| 26 | Agile Sciences Develops anti-bacterial small molecules | $2M | 72 mo ago | 11 | 2007 | — | — | — | — |
| 27 | Phitonex Innovative flow cytometry solutions with NovaFluor dyes and conjugated antibodies | $2M | 80 mo ago | 11 | 2017 | Chris Dwyer Co-Founder & CSO | — | 17 patents Nucleic‑acid bioconjugates enabling multiplexed single‑cell assays and signal amplification | — |
| 28 | Benanova Sustainable materials company creating nature-inspired colloid solutions for diverse markets | $2M | 23 mo ago | — | 2013 | Alexander Richter Co-Founder | — | 8 patents Patents concentrated in health & consumer products | — |
| 29 | Flag Therapeutics Developer of small molecule therapeutics for difficult-to-treat cancers | $2M | 83 mo ago | 2 | 2013 | Frank Sorgi President & CEO | — | — | — |
| 30 | LigaTrap Technologies Innovating bioprocess purification technologies for complex biologics and advanced therapies | $2M | 100 mo ago | 9 | 2015 | — | — | — | 2 partnerships |
| 31 | Quadvantage Developer of medical devices for orthopedic surgery | $1M | 32 mo ago | 2 | 2020 | Tom Gutierrez CEO | — | — | — |
| 32 | GeneVentiv Therapeutics Developer of therapeutic solutions for the treatment of hematology disorders | $1M | 13 mo ago | 2 | 2020 | Damon Race CEO & President | — | — | — |
| 33 | Genoverde Provider of genetically engineering plants for higher carbon sequestration | $1M | 93 mo ago | — | 2015 | Samuel Hazen Co-Founder & CSO | — | — | — |
| 34 | Xanofi Nano-fibres for healthcare applications | $825K | 169 mo ago | 9 | 2010 | Miles Wright CEO & Board of Directors | — | 8 patents Nanofiber-based substrates and coatings for enhanced cell culture, hydrophobic surfaces, and dispersion technologies. | — |
| 35 | Vogenx Developer of therapeutics for the treatment of serious metabolic and gastrointestinal diseases | $750K | 6 mo ago | — | 2020 | James Green Chief Executive Officer | — | 9 patents Patents concentrated in health & consumer products | — |
| 36 | Impulse Wellness Developer of wearable sensor technology for physiological data and health insights | $675K | 36 mo ago | — | 2023 | Brady Adcock Co-Founder & Chief Technology Officer | — | 3 patents Personalized wearable biosignal monitoring devices for therapeutic feedback | — |
| 37 | Sapere Bio Diagnostic company that develops non-invasive biomarker tests to measure cellular aging and predict the risk… | $500K | 23 mo ago | 5 | 2013 | Norman Sharpless Co-Founder | — | — | — |
| 38 | Acorn Applications Cloud-Based Analytic Clinical Research Solutions | $500K | 132 mo ago | — | 2013 | Gordon Jones Founder & CEO | — | — | — |
| 39 | Novocor Nervous system regulation through data-driven somatic exercises and evidence-based practices | $337K | 134 mo ago | — | 2013 | Tony Voiers Co-Founder & CEO | — | — | — |
| 40 | BreStem Developer of stem cell and exosome therapies for the treatment of chronic lung diseases | $300K | 59 mo ago | 2 | 2017 | Ke Cheng Founder | — | — | — |
| 41 | MAA Laboratories Transforming molecules into next-generation therapies through advanced nanoparticle technology | $225K | 108 mo ago | 16 | 2013 | Anjani Jha CEO & President | — | — | — |
| 42 | BrainTrip Manufacturer of a wearable device for detecting behavioral changes | $215K | 73 mo ago | 10 | 2017 | Maximiliano Romero CEO | Framer SitesReactLenis+6 | — | — |
| 43 | Avana Health Developer of treatments for women health | $128K | 8 mo ago | 6 | 2021 | Peter Pacult Co-Founder & CEO | Cart FunctionalitySquarespace CommerceSquarespace+10 | — | — |
| 44 | NanoVector Biologic nanoparticle-based therapeutic drug delivery system | $125K | 204 mo ago | — | 2007 | Albert Bender CEO | — | 2 patents Engineering viral vectors for gene delivery and therapeutic applications | — |
Top 12 Life Sciences companies in Raleigh
#1
Series A · Raleigh, North Carolina · founded 2026$130Mraised▾
Developer of therapeutics for the treatment of migraine and other headache disorders. The company is focused on developing next generation therapeutics targeting PACAP for the treatment and prevention of migraine and other headache disorder
- Feb 2026Series A$130M
#2
Series C · Raleigh, North Carolina · founded 2018 · 10 employees$123Mraised▾
Bryn Pharma has developed nasal based epinephrine for anaphylaxis. The company has developed a portable epinephrine auto-injector that can also be used as an intranasal epinephrine delivery system to treat allergic reactions or an anaphylactic reaction.
- Apr 2025Series C$4.7M
- Jul 2023Series C$26.7M
- Oct 2022Series C$43.5M
- Jun 2020Series B$26M
#3
Acquired · Raleigh, North Carolina · founded 2011 · 31 employees$174.6Mraised▾
Sprout Pharmaceuticals has developed drugs for women's health. The company has developed an FDA-approved non-hormonal pill called ADDYI to cure Hypoactive Sexual Desire Disorder (HSDD) in premenopausal women.
- Dec 2024Series D$10.6M
- Apr 2023Series D$7.1M
- Aug 2022Series D$28M
- May 2022Series D$25.1M
#4
Funding Raised · Raleigh, North Carolina · founded 2013 · 4 employees$23.3Mraised▾
Developer of glycan-based therapeutics for coagulation and thrombo inflammation.The company is developing drug therapies based on a novel synthetic carbohydrate technology platform. The platform technology can be used to synthesize an anticoagulant drug, like synthetic heparin, as well as design heparin-like oligosaccharides for research and development for other medical applications.
- Apr 2025Grant (prize money)$454.7K
- Apr 2025Grant (prize money)$2.4M
- Sep 2023Grant (prize money)$1.3M
- Sep 2023Grant (prize money)$347.5K
#5
Series A · Raleigh, North Carolina · founded 2014 · 8 employees$36Mraised▾
Developing an inhaled approach to treat lung disease with excess mucus and mucus plugs. It offers AER-01 a thiol-modified carbohydrate which cleaves mucin disulfide bridges to liquefy mucus plugs and treat muco-obstructive lung diseases.
- Jan 2025Series A$5M
- Dec 2022Series A$36M
#6
Funding Raised · Raleigh, North Carolina · founded 2019 · 5 employees$2.8Mraised▾
Developer of therapeutics for hemostasis and wound healing. It offers platelet-mimetic therapeutics for the treatment of uncontrolled bleeding.
- Aug 2025Grant (prize money)$2M
- Sep 2022Grant (prize money)$229.5K
- Jun 2022Conventional Debt$100K
- Mar 2022Grant (prize money)$258.5K
#7
Funding Raised · Raleigh, North Carolina · founded 2020$750Kraised▾
Developer of therapeutics for the treatment of serious metabolic and gastrointestinal diseases. The company's product line include Mizagliflozin which is a small molecule inhibitor of sodium glucose transporter 1 (SGLT1) which act on intestinal lumen for the treatment of post bariatric hypoglycemia.
- Dec 2025Conventional Debt$750K
#8
Series B · Raleigh, North Carolina · founded 2015 · 74 employees$67.3Mraised▾
Developer of therapeutics for infectious disease and inflammatory indications. The company has developed a platform to design and deliver custom CRISPR-Cas systems directly to specific bacteria and enables the development of antimicrobials for infectious diseases.
- Jan 2024Grant (prize money)$23.9M
- May 2022Series B$35M
- Oct 2021Conventional Debt—
- Nov 2020Conventional Debt$20M
#9
Funding Raised · Raleigh, North Carolina · founded 2019$2.4Mraised▾
Developer of gene therapy using AAV capsids and immune modulators. The company focuses on adapting natural mechanisms for safe, single-dose therapeutics. It researches human-tropic and antibody-evading AAV capsids. The company also develops single-chain immune modulators for therapeutic applications.
- Mar 2025Grant (prize money)$328.1K
- Sep 2022Grant (prize money)$261.1K
- Sep 2021Grant (prize money)$328.1K
- Sep 2020Grant (prize money)$1.2M
#10
Seed · Raleigh, North Carolina · founded 2020 · 2 employees$1.4Mraised▾
Developer of therapeutic solutions for the treatment of hematology disorders. The company is involved in the development of gene therapy-based solutions and drug candidates that help to deliver healthy genes to a variety of cell targets within the body. It provides solutions for treating liver-directed diseases such as hemophilia, lysosomal storage disorders, and inherited ocular diseases by using optimized codon, a strong liver promoter, and novel cleavage sequence technologies.
- May 2025Grant (prize money)$2.5M
- Mar 2025Grant (prize money)$2.5M
- Apr 2024Grant (prize money)$1.2M
- Aug 2022Seed$1.4M
#11
Series D · Raleigh, North Carolina · founded 2005 · 33 employees$66Mraised▾
Provider of vascular stenting with embolic protection for both coronary and peripheral vasculature. The company's product offering includes Corguard - coronary stent system with integrated embolic protection; Vanguard - peripheral dilation balloon with integrated embolic protection; Paladin - carotid post-dilation balloon with integrated embolic protection.
- Apr 2023Series D$23M
- Apr 2022Series D$15.1M
- Jun 2020Series C—
- Jan 2020Series C$22.3M
#12
Seed · Raleigh, North Carolina · founded 2021 · 6 employees$127.5Kraised▾
Developer of treatments for women health. The company aims to provide women with treatments for Postpartum Hemorrhage (PPH) and Abnormal Uterine Bleeding (AUB) that are accessible anywhere in the world.
- Sep 2025Seed$2.8M
- Nov 2022Seed$127.5K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Life Sciences coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Biotechnology is moving in the United States
A read on the academic research around Biotechnology — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 6,260 United States-affiliated papers.
- Harvard University209
- Cornell University177
- University of Tennessee at Chattanooga140
- Howard Hughes Medical Institute126
- Johns Hopkins University121
- Gene33→164
- Transcription (linguistics)11→79
- Antibody11→62
- Genome6→56
- Mutation7→56
- Gene8→110
- Cell culture3→62
- Gene expression3→62
- Fermentation2→54
- Downregulation and upregulation1→50
- Agriculture19→58
- Antibiotic resistance15→45
- Public health4→31
- Gene6→30
- Production (economics)5→29
Where biotechnology is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing biotechnology patents in the United States
United States biotechnology patent filing is accelerating — 457,918 filings from 8,000 assignees (2016–2025), led by Genentech, UNIV California, Regeneron Pharma; annual filings 36884→44446.
- Genentech18078
- UNIV California17948
- Regeneron Pharma16082
- Amgen10495
- Monsanto Technology9742
- UNIV Pennsylvania8521
- Harvard College7460
- UNIV Texas7378