Best Life Sciences Companies in Sheffield, United Kingdom
The 36 best Life Sciences companies in Sheffield, United Kingdom in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Rinri Therapeutics.
Our analysis of 62 Life Sciences companies
$9.8b in tracked funding; 75% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2026.
Ranked: Best Life Sciences companies in Sheffield
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Rinri Therapeutics Provider of regenerative stem cell-based therapies for the treatment of hearing loss | $16M | 65 mo ago | Series A | Simon Chandler CEO and Director | 2018 | WordPressMySQLPHP+19 | — | — |
| 2 | Phase Focus Provider of virtual lens that generates High definition images without high-quality lenses | $12M | 36 mo ago | Acquired | Martin Humphry Chief Executive Officer | 2006 | Concrete CMSPHPVimeo+15 | 135 patents Object tracking and temporal behavior analysis using 3D imaging and computer vision | — |
| 3 | Zilico Real-time diagnostics for cancer. | $9M | 103 mo ago | Series A | — | 2006 | — | 2 patents Biomedical tissue impedance measurement devices for diagnostic and research applications. | — |
| 4 | CellTran Dressings, hydrogels for wound management. | $7M | 228 mo ago | Acqui-Hired | Malgosia Jarmolowicz CEO | 2000 | — | 4 patents Cell-based therapeutic delivery systems and lysate-derived pharmaceutical compositions. | — |
| 5 | SleepCogni Provider of a bedside sleep device to induce sleep 16Innovation top 32%Product top 46%Talent bottom 49%Funding bottom 45% All 8 signals ▾Innovationtop 32% Producttop 46% Talentbottom 49% Fundingbottom 45% Globalbottom 32% Techbottom 31% Newsbottom 18% Marketbottom 10% Innovation: 2 product lines · Deep-tech classification: Tech Hardware Product: 2 distinct product lines · Company stage: Series A rank vs industry peers · Fliar Intelligence Index 16/100 | $4M | 21 mo ago | Series A | Maan Werken Founder & CSO | 2015 | — | — | — |
| 6 | Absynth Biologics Developer of vaccines and antibodies to treat bacterial infections | $4M | 113 mo ago | Deadpooled | Simon Foster Co-Founder | 2007 | — | 52 patents Bacterial and peptide-based combination vaccines for infectious disease prevention | — |
| 7 | Unicorn Biotechnologies Developer of bioreactors for cell-based manufacturing | $3M | 52 mo ago | Seed | Jack Reid Co-Founder | 2020 | WebflowGSAPMicrosoft Clarity+13 | 6 patents Automated anchorage‑dependent cell culture passaging and sterile fluidic connector interfacing systems | — |
| 8 | Crucible Therapeutics Developer of RNA-targeting therapies for neurodegenerative diseases | $3M | 15 mo ago | Funding Raised | Guillaume Hautbergue Chief Scientific Officer | 2023 | — | — | — |
| 9 | SynGenSys Company creates product-specific libraries of synthetic genetic parts | $2M | 29 mo ago | Seed | David James Co-Founder | 2021 | — | — | — |
| 10 | Blackfin Bio Developer of gene therapies for the treatment of rare diseases | $317K | 33 mo ago | Seed | Mimoun Azzouz Co-Founder | 2022 | WordPressProton MailMySQL+12 | — | — |
| 11 | Perlemax Commercializing chemical and biochemical engineering technologies centered around microbubbles and plasma… | $122K | 136 mo ago | Seed | Will Zimmerman Founder & CTO | 2010 | — | 45 patents Fluidic oscillators enabling efficient mixing and low‑heat‑exchange mass transfer processes. | — |
| 12 | Cytiva Online shop for life science software and products for research work | — | 35 mo ago | Funding Raised | Emmanuel Ligner CEO & President | 1968 | SitecoreMicrosoft ASP.NETVideoJS+28 | 4 patents Innovative small‑volume fluid mixing and filtration recovery solutions for bioprocess labs | — |
Top 12 Life Sciences companies in Sheffield
#1
Funding Raised · Sheffield, England · founded 2023$3.1Mraised▾
Developer of RNA-targeting therapies for neurodegenerative diseases. It focuses on the most common genetic forms of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD), developing treatments that prevent rogue RNAs from escaping into the cytoplasm where they cause damage. The approach uses RNA interference to reduce toxic protein levels, aiming to slow or halt disease progression. Research originates from internationally recognized institutes in neurodegenerative disease research, leveraging expertise in RNA biology, gene therapy, and clinical development. The goal is to develop curative treatments for these debilitating conditions.
- Jun 2025Grant (prize money)$3.1M
#2
Series A · Sheffield, England · founded 2015 · 3 employees$4.4Mraised▾
Provider of a bedside sleep device to induce sleep. It customizes the treatment based on the user's physiological profile and sleep environment and delivers a program of audio, visual, and tactile cues to the user. The device is triggered manually and monitors the user's heart rate, mental alertness, skin temperature, and movement through sensors worn on the user's index finger.
- Dec 2024Series A$379.7K
- Nov 2021Series A$1.9M
- Nov 2021Conventional Debt—
- Jul 2021Seed$660.5K
#3
Acquired · Sheffield, England · founded 2006 · 10 employees$12.1Mraised▾
Provider of virtual lens that generates High definition images without high-quality lenses. It develops a lensless imaging method. It also finds analytical applications in life sciences and engineering metrology and in multiple wavelength regimes like visible light, X-ray, electron, and others.
- Aug 2023Series B$191.2K
- Jul 2012Series B$5M
- Jul 2009Series A$5.7M
- Feb 2008Seed$1.2M
#4
Seed · Sheffield, England · founded 2021 · 6 employees$2.3Mraised▾
SynGenSys is a biotechnology research company that creates product-specific libraries of synthetic genetic parts for next-generation biomedicines and biomanufacturing processes. They aim to rely on engineering principles to create a library of genetic building blocks.
- Apr 2024Seed$2.3M
#5
Series A · Sheffield, England · founded 2018 · 9 employees$15.7Mraised▾
Provider of regenerative stem cell-based therapies for the treatment of hearing loss. The company's novel technology is to replace damaged or dead sensory cells of the inner ear with stem cell therapy and restore hearing. The company is inducing differentiation from human embryonic stem cells (hESCs) using signals involved in the initial specification of the otic placode.
- Apr 2021Series A$13.9M
- May 2019Seed$1.8M
#6
Seed · Sheffield, England · founded 2020 · 5 employees$3.2Mraised▾
Developer of bioreactors for cell-based manufacturing. The company has developed automated biomanufacturing systems, to unlock cost-efficient platforms for rapidly scaling cultivated meat manufacturing and enabling the transition to animal-free agriculture.
- Apr 2022Seed$3.2M
- 2021Seed—
- 2020Seed—
#7
Seed · Sheffield, England · founded 2022$317.4Kraised▾
Developer of gene therapies for the treatment of rare diseases. The company accelerate clinical development and commercialisation of promising gene therapy products for rare and other diseases of the Central Nervous System.
- Dec 2023Seed$317.4K
#8
Series A · Sheffield, England · founded 2006 · 15 employees$8.6Mraised▾
Zilico is developing cancer diagnostics that will provide a real-time diagnosis for cervical cancer . The company is focused on developing a range of products that utilize Electrical Impedance Spectroscopy (EIS) as a platform technology to provide diagnostics for certain cancers. Its lead product ZedScan is a diagnostic system that is used alongside colonoscopy to provide an objective assessment of the cervical epithelial tissue in real time. Two applications are under development: the first for the referral market and the second for the screening market. In addition, Zilico has completed a proof-of-concept clinical study utilizing EIS to discriminate between different oral tissues, including neoplasia.
- Feb 2018Series A$7M
- Jun 2012Seed$1.5M
#9
Deadpooled · Sheffield, England · founded 2007 · 3 employees$3.8Mraised▾
Developer of vaccines and antibodies to treat bacterial infections. The company has established a vaccine pipeline targeting the pathogens Staphylococcus aureus, Clostridium difficile, and Streptococcus pyogenes. Also developing monoclonal antibodies that specifically recognize S. aureus.
- Apr 2017Seed$435.4K
- Nov 2015Seed$375.8K
- Jul 2015Seed$272.8K
- Jun 2014Seed$1.2M
#10
Acqui-Hired · Sheffield, England · founded 2000 · 11 employees$6.8Mraised▾
CellTran engages in the research and development of products for the regeneration of tissue and the healing of wounds. It offers Myskin that is used for the treatment of difficult to heal wounds; Lyphoderm, a freeze-dried lysate from cultured human keratinocytes that is formulated into a hydrophilic gel; and Ulcodress, an integrated wound care dressing that provides control of moisture, infection, and proteases within the wound area. It provides skin banking services, as well as contract manufacture services in the fields of materials fabrication and cell culture. As of October 28, 2008, CellTran operates as a subsidiary of York Pharma.
- Aug 2007Series A$2M
- Aug 2005Series A$4.8M
#11
Seed · Sheffield, England · founded 2010 · 3 employees$122.3Kraised▾
Perlemax is a technology development company formed to commercialize technologies developed by Prof. William Zimmerman, Professor of Biochemical Dynamical Systems at the University of Sheffield, specifically to find applications of their microbubble and plasma microreactor technologies. The company is developing a method to capture carbon from steel plant exhaust with algae using its microbubble technology, increasing the overall recovery efficiency of algal biomass to 99.2%. Microbubble technology is also being applied to developing solutions to increasing the efficiency of methane production in anaerobic cultures by almost 100%. In addition, the company's fluidic oscillator technology finds application in its collaboration with Yorkshire Water to improve supplementary oxygenation of intensive recirculation systems used in aquaculture, and in waste water treatment solutions.
- May 2015Seed—
- Jul 2013Seed—
- Jan 2011Seed$122.3K
#12
Funding Raised · Sheffield, England · founded 1968 · 510 employees—raised▾
Online shop for life science software and products for research work. The company provides solutions for biological research, clinical therapy diagnosis, and more. Few products of the company are Xcellerex APS for downstreaming processes, IN Carta SINAP (microscope for cell analysis), DeltaVision imaging systems, and more. The company has sequencing technology and tools for research, drug discovery.
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Life Sciences coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
What Sheffield researches in biotechnology
- University of Sheffield18
- Sheffield Hallam University1
- Sheffield Kidney Institute1
- Sheffield Teaching Hospitals NHS Foundation Trust1
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.