Best Life Sciences Companies in South Holland, Netherlands
The 144 best Life Sciences companies in South Holland, Netherlands in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Crucell.
Our analysis of 576 Life Sciences companies
$91.7b in tracked funding; 70% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Life Sciences companies in South Holland
| # | Company | Disclosed funding | Last round | Stage | Employees | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Crucell Crucell researches and develops products and markets vaccines, proteins and antibodies for the treatment of… | $443M | 125 mo ago | Acquired | 1,300 | — | — | — | — |
| 2 | Pharvaris Orally deliverable bradykinin B2 antagonists for hereditary angioedema | $164M | 67 mo ago | Public | 66 | Berndt Modig Co-founder & CEO | WordPressApple iCloud MailMicrosoft 365+28 | 4 patents Novel small‑molecule bradykinin B2 receptor antagonists for therapeutic use | 2 job openings |
| 3 | Micreos Develops targeted antibacterial products to replace antibiotics | $109M | 43 mo ago | Series D | 120 | Mark Offerhaus CEO | — | 12 patents Phage-based biocontrol for food safety and animal growth enhancement | — |
| 4 | Vico Developer of RNA modulating therapies for genetic neurological diseases | $103M | 23 mo ago | Series B | 38 | Judith Van Deutekom Scientific Co-Founder and Advisor | WordPressMySQLPHP+16 | — | — |
| 5 | Ncardia Company offering hiPSC based products and services for drug discovery and development | $77M | 55 mo ago | Series C | 79 | Stefan Braam Co-Founder & President | HubSpot CMS Hubcore-jsjQuery+12 | 35 patents Manufacturing and differentiation of pluripotent stem cell-derived cardiomyocytes for therapeutic use. | 1 launch |
| 6 | Varmx Therapeutic proteins to restore blood clotting in bleeding patients | $77M | 36 mo ago | Series B | 10 | Pieter Reitsma Founder | — | — | — |
| 7 | AkkoLens Developer of Intraocular lenses with shifting optical elements | $48M | 29 mo ago | Series A | — | Michael Rombach Founder & CTO | — | — | — |
| 8 | ISA Pharmaceuticals Developer of therapeutic vaccines for cancer and infectious diseases | $41M | 59 mo ago | Series B | 44 | — | — | 90 patents Peptide-based cancer vaccines and immunogenic formulations combined with PD‑1 inhibition | — |
| 9 | Anavo Therapeutics Developer of drugs for cancer treatment | $33M | 37 mo ago | Seed | 10 | Birgit Zech CEO | Squarespace CommerceSquarespaceVimeo+12 | 3 patents Small-molecule WIP1 phosphatase inhibitors for cancer therapy | 1 job opening |
| 10 | Cradle Provider of chemoproteomics solutions for protein design and development 57AI top 20%Funding top 29%Growth top 35%Talent top 38% All 8 signals ▾AItop 20% Fundingtop 29% Growthtop 35% Talenttop 38% Moattop 42% Techtop 49% Globalbottom 38% Marketbottom 29% AI: Classified as an AI company Funding: Raised $33.0M across 3 rounds · 3 rounds over 4 yrs (0.8/yr) rank vs industry peers · Fliar Intelligence Index 57/100 | $33M | 18 mo ago | Series B | 14 | Stef Grieken Co-Founder & CEO | Framer SitesApple iCloud MailGoogle Workspace+15 | — | 1 job opening |
| 11 | ProFibrix Powdered fibrin sealant for surgical bleeding | $33M | 178 mo ago | Acquired | 25 | — | — | 112 patents Recombinant fibrinogen production and dry‑powder hemostatic delivery device technologies. | — |
| 12 | Mimetas Develops microfluidics-based organ-on-a-chip tissue models | $29M | 45 mo ago | Series B | 108 | Paul Vulto Co-Founder & Co-CEO | Webflowcore-jsjQuery+12 | 86 patents Microfluidic organ-on-a-chip platforms for 3D tissue and vascular modeling | 1 launch |
| 13 | Azafaros Developer of small molecule based therapeutics for the treatment of rare metabolic disorders | $28M | 13 mo ago | Series B | 17 | Stefano Portolano CEO | PleskLiteSpeedMicrosoft Advertising+11 | 17 patents Glucosylceramide synthase inhibitor drugs and their crystalline forms for lysosomal storage disease therapy | 1 award |
| 14 | NightBalance Sleep position training device for positional sleep apnea patients | $14M | 119 mo ago | Acqui-Hired | 14 | — | — | 48 patents Oral sleep‑apnea devices and wearable sleep‑position monitoring/training systems | — |
| 15 | Bluebee Provider of solutions for genomics data analysis | $13M | 122 mo ago | Acquired | 31 | — | — | — | — |
| 16 | Artica Therapeutics Developer of small molecule therapeutics for immunological disorders | $13M | 31 mo ago | Seed | — | Arwin Ridder Co-Founder | WebflowMicrosoft 365jQuery+6 | — | — |
| 17 | Amarna Therapeutics Developer of immune-modulating gene therapies for rare and prevalent autoimmune diseases and genetic diseases | $11M | 80 mo ago | Series A | 30 | Marjanne Messie CFO | CMS Made SimplePleskPHP+15 | 5 patents Patents concentrated in chemistry & materials | — |
| 18 | DEBx Medical Developer of treatments for chronic wounds | $11M | 19 mo ago | Late Stage | 11 | Alberto Cogo Co-Founder | WordPressApple iCloud MailMySQL+23 | 20 patents Advanced wound debridement and antimicrobial silver-based dressings for tissue removal | 1 launch |
| 19 | Amber Implants Developer of spinal implants for vertebral fracture | $10M | 60 mo ago | Series A | 10 | Banafsheh Sajadi Co-Founder | WordPressMySQLPHP+26 | — | — |
| 20 | ProteoNic Provider of products and services for improving recombinant protein production levels | $8M | 176 mo ago | Series A | 20 | Frank Pieper CEO | WordPressMySQLPHP+23 | — | — |
| 21 | Sensius Developer of a hyperthermia system for cancer treatment. | $8M | 12 mo ago | Series B | — | Paul Den Biggelaar Co-Founder & CEO | — | — | — |
| 22 | DCprime Developer of immunotherapeutic solutions for treating cancer | $7M | 124 mo ago | Acquired | 25 | — | — | 50 patents Novel dendritic cell-based cancer vaccines and tumor‑independent antigen immunotherapies | — |
| 23 | Pepscope Provider of services for proteomics using microarray and mass spectrometry | $5M | 66 mo ago | Deadpooled | — | Jos Joore Co-Founder & CEO | — | — | — |
| 24 | Arcarios Discovers and develops drugs that target bone and joint diseases | $5M | 189 mo ago | Seed | 5 | — | — | 22 patents Cyclodextrin-based derivatives for drug delivery, biologics, and extracellular matrix therapeutics | — |
| 25 | STIL Developer of a wearable device for tremor suppression | $5M | 41 mo ago | Seed | — | IJsbrand Lange Founder & CEO | — | 6 patents Medical wearable braces for body support and orthopedic injury treatment | — |
| 26 | Pan Cancer T Provider of TCR T-cell therapeutics for the treatment of cancer | $5M | 6 mo ago | Series A | 8 | Reno Debets Founder | WordPressMySQLPHP+13 | — | — |
| 27 | MyLife Technologies Developer of a nanotech-based drug delivery system | $4M | 55 mo ago | Series A | 12 | — | — | — | — |
| 28 | Delmic B.V. Provider of light and electron microscopy solutions for life sciences and materials science | $4M | 38 mo ago | Series A | 50 | Sander Hoedt CEO | HubSpot CMS HubRequireJSLazySizes+19 | 88 patents Focused ion beam micromachining and multi-beam charged‑particle sample inspection systems | — |
| 29 | BIOND Solutions Developer of organ-on-chip platform for cell-based assays | $4M | 51 mo ago | Series A | 13 | — | WordPressMySQLPHP+28 | 16 patents Integrated microfluidic chambers for 3D muscle tissue engineering and organ‑on‑chip platforms | — |
| 30 | Kaminari Medical Developer of diagnostic solution for vulnerable plaque in the coronary arteries | $4M | 20 mo ago | Series A | 6 | Jeroen Kodde CEO | — | — | 1 job opening |
| 31 | Harbour Antibodies Production of antibodies and VH (heavy chain with one variable) domains for therapy | $3M | 75 mo ago | Acquired | 10 | — | — | 25 patents Therapeutic antibodies and antibody‑nanoparticle conjugates for targeted disease treatment | — |
| 32 | Facio Therapies Provider of small molecule therapeutics for Facioscapulohumeral Dystrophy | $3M | 128 mo ago | Series A | 7 | David Dasberg CEO | — | — | — |
| 33 | Genewity Biotech company focused on commercializing potentially groundbreaking therapies in the field of cell and gene… | $3M | 39 mo ago | Funding Raised | — | Arno Bisschop Co-Founder & CEO | — | 2 patents Artificial thymus creation for immune cell therapy and regenerative immunology | — |
| 34 | Allero Therapeutics Developer of immunotherapies for allergy and autoimmune disease | $3M | 45 mo ago | Seed | 5 | Kees Leenhouts Co-Founder / Chief Technology Officer & Chief Operations Officer | — | 3 patents mRNA and antigen-specific immunotherapies for treating immune disorders and viral‑induced inflammation | — |
| 35 | SkylineDX Provider of gene expression profiling tests for personalized medicine | $2M | 53 mo ago | Seed | 61 | Dharminder Chahal CEO | WordPressMySQLPHP+19 | 27 patents Predictive gene expression biomarkers for melanoma metastasis and treatment response | — |
| 36 | STIL Orthosis Developer of medical device to alleviate tremors and enhancing voluntary movement | $2M | 12 mo ago | Seed | 7 | IJsbrand Lange Co-Founder & CEO | WordPressMySQLPHP+20 | — | — |
| 37 | Toxys Developer of In vitro genotoxicity testing services | $2M | 75 mo ago | Public | 23 | — | WordPressApple iCloud MailMicrosoft 365+42 | 3 patents In vitro embryonic development assays for toxicology and drug safety evaluation. | 2 launchs |
| 38 | DAB Technology solutions provider for accelerated fermentation | $2M | 7 mo ago | Series A | 20 | Kirsten Herben-Steinbusch Founder | SanityRadix UITailwind CSS+18 | — | — |
| 39 | SLAM Orthopedic Developer of solutions for orthopedic surgical applications | $2M | 25 mo ago | Seed | — | Bart Kolling Co-Founder | — | — | — |
| 40 | IPD Provider of treatment for prosthetic joint & metal implant infections | $2M | 60 mo ago | Seed | 2 | Richard Wateringen CEO | — | — | — |
| 41 | TherageniX Developer of non-viral delivery system for tissue regeneration | $1M | 33 mo ago | Funding Raised | — | Anandkumar Nandakumar Co-Founder & CEO | — | — | — |
| 42 | GenomeScan Provider of next-generation genome sequencing and testing | $1M | 43 mo ago | Funding Raised | 38 | Peter Belt CEO | WordPressMySQLPHP+28 | — | 1 job opening · 1 internship |
| 43 | BaseClear Contract service laboratory with a focus on DNA technology, genomics and synthetic biology. | $1M | 82 mo ago | Funding Raised | 96 | — | WordPress Block EditorCart FunctionalityWordPress+27 | — | 3 job openings · 4 internships |
| 44 | XS Innovations Developer of medical device for chronic kidney disease treatments | $1M | 21 mo ago | Seed | — | Joris Rotmans Co-Founder | — | 50 patents Patents concentrated in health & consumer products | — |
| 45 | VitroScan Provider of a diagnostic platform for precision treatments for cancer patients | $901K | 18 mo ago | Seed | 6 | Willemijn Vader Managing Director | — | 8 patents Ex vivo tumor organoid platforms for immune response measurement and personalized immunotherapy | 1 partnership |
| 46 | 20Med Therapeutics Develops RNA-based therapeutics and vaccines for drug delivery | $736K | 37 mo ago | Series A | 13 | Michiel Lodder CEO | — | 15 patents Patents concentrated in chemistry & materials | — |
| 47 | Levels Developer of diagnostic tools for the treatment of infectious diseases | $417K | 29 mo ago | Seed | — | Blandine Tallec Co-Founder | — | — | — |
| 48 | Fibriant Develops variants of fibrinogen protein for therapeuticapplication | $316K | 50 mo ago | Seed | 9 | Jaap Koopman CEO | — | 17 patents Fibrinogen-based adjuvant formulations enhancing antimicrobial and therapeutic peptide efficacy | — |
| 49 | OASYS NOW Provider of medical data processing solutions for healthcare organizations | $275K | 18 mo ago | Seed | 12 | Soroosh Torabi Co-Founder | Framer SitesApple iCloud MailGoogle Workspace+13 | — | — |
| 50 | BIMINI Biotech Developer of therapeutics for the treatment of cancer | $238K | 17 mo ago | Seed | 4 | Ger Strous Co-Founder | — | — | 1 expansion |
Top 12 Life Sciences companies in South Holland
#1
Series A · Rotterdam, South Holland · founded 2020 · 8 employees$4.6Mraised▾
Provider of TCR T-cell therapeutics for the treatment of cancer. The company uses the adoptive T cell therapies for treating pan-cancer. The company pipeline product includes MAGE-C2/HLA-A2 TCR and epigenetic drugs which can be used in the treatment of melanoma and head-and-neck carcinoma. The company also offers Pan-Cancer T’s platforms which include a dose-escalation of TCR T cells.
- Dec 2025Series A$5.8M
- Dec 2025Conventional Debt$5.8M
- Jul 2024Seed$4.6M
- Oct 2021Seed—
#2
Series B · Leiden, South Holland · founded 2018 · 17 employees$27.5Mraised▾
Developer of small molecule based therapeutics for the treatment of rare metabolic disorders. It has developed products for patients suffering from lysosomal storage disorders (LSDs) and LSD-related diseases. The compounds interfere with the metabolism of glycolipids that is disturbed in these patients.
- May 2025Series B$146M
- Feb 2020Series A$27.5M
- Jul 2018Seed—
#3
Series B · Rotterdam, South Holland · founded 2015$7.5Mraised▾
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- Jun 2025Series B$17.2M
- Feb 2023Series A$7.2M
- 2022Grant (prize money)$2.8M
- Jan 2022Grant (prize money)$2.8M
#4
Series A · Delft, South Holland · founded 2012 · 20 employees$2.2Mraised▾
DAB is a technology solutions provider for accelerated fermentation. It enables the production of chemicals, materials, and fuel from renewable feedstock. It also provides solutions for fermentations with a water-insoluble product.
- Oct 2025Series A—
- May 2019Series A$2.2M
#5
Series B · Leiden, South Holland · founded 2019 · 38 employees$103.3Mraised▾
Developer of RNA modulating therapies for genetic neurological diseases. The company uses VICOMER antisense oligonucleotide platform to design RNA modulating therapeutics to address specific genetic defects such as Rett syndrome, Alzheimer’s disease, Huntington disease, and more. The company's lead candidate is VO659 for multiple polyglutamine disorders, spinocerebellar ataxia type 3 and type 1 and Huntington’s disease.
- Jun 2024Series B$12.3M
- Jan 2024Series B$60M
- Jul 2020Series A$31M
#6
Series B · Delft, South Holland · founded 2021 · 14 employees$33Mraised▾
Provider of chemoproteomics solutions for protein design and development. The platform enables researchers to design proteins using predictive algorithms and AI design suggestions. It also offers 3D structure prediction, optimizing thermostability and codon expression.
- Nov 2024Series B$73M
- Nov 2023Series A$24M
- Nov 2022Seed$5.7M
#7
Seed · Delft, South Holland · founded 2016 · 7 employees$2.3Mraised▾
Developer of medical device to alleviate tremors and enhancing voluntary movement. The flagship product the STIL Orthosis that features specialized dampers that suppress tremors, allowing individuals to perform daily activities for the treatment of tremor disorders.
- May 2025Seed$2.3M
#8
Late Stage · Rotterdam, South Holland · founded 2019 · 11 employees$10.8Mraised▾
Developer of treatments for chronic wounds. It develops products to eliminate biofilms and infections. It offers an application process suitable for various healthcare settings, designed to address the removal of infected tissue, facilitating wound bed preparation. It helps users to improve the treatment experience for both patients and healthcare providers.
- Nov 2024PE—
- May 2023PE$10.8M
#9
Series A · Rotterdam, South Holland · founded 2018 · 6 employees$4.2Mraised▾
Kaminari Medical is developing a diagnostic solution for vulnerable plaque in the coronary arteries. The company has developed the ultrasound (ivus) and photoacoustic (pa) imaging that can provide information about plaque location and composition.
- Oct 2024Series A$4.2M
- Oct 2024Conventional Debt$1.6M
- Dec 2019Grant (prize money)—
#10
Series B · Leiden, South Holland · founded 2015 · 10 employees$77.2Mraised▾
VarmX, a spin-out company from the Leiden University Medical Center, is focussed on development and manufacturing of therapeutic proteins to restore blood clotting in bleeding patients. Its lead product PseudoXa is a modified recombinant human coagulation factor X and is being developed to restore blood clotting in the presence of direct factor Xa anticoagulants (DOACS) such as rivaroxaban, apixaban, and edoxaban. DOACS are taken by patients for the prevention and treatment of thrombosis and stroke, but as a side effect severe bleeding often occurs.
- May 2023Series B$32.3M
- Sep 2022Grant (prize money)$2.5M
- Oct 2021Grant (prize money)—
- 2021Grant (prize money)$56.5K
#11
Series A · Rijswijk, South Holland · founded 2005$48.1Mraised▾
Developer of Intraocular lenses with shifting optical elements. It offers Lumina lens, an accommodative intraocular lens that can restore vision and accommodation. It uses spring like haptics to allow movement perpendicular to the optical axis, enhancing focal change and providing clear vision without glasses for patients with cataractand presbyopia.
- Jan 2024Series A$48.1M
#12
Series D · The Hague, South Holland · founded 2005 · 120 employees$109Mraised▾
Micreos develops targeted antibacterial products to replace antibiotics. The company provides Micreos endolysin technology that can kill unwanted bacteria including antibiotic-resistant strains while leaving the beneficial bacteria intact. The company is also involved in the development of Micreos' Staphefekt SA.100 enzyme (endolysin), which can kill Staphylococcus aureus and MRSA. It is also suitable for routine maintenance therapy, for people with skin conditions with an infectious component, such as acne, eczema, psoriasis, and rosacea. The compnay products are FDA-approved.
- Oct 2022Series D$24.6M
- Dec 2021Grant (prize money)$56.6K
- Sep 2021Series D$37.3M
- Nov 2019Grant (prize money)$2.8M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Life Sciences coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Biotechnology is moving in the Netherlands
A read on the academic research around Biotechnology — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 513 Netherlands-affiliated papers.
- Wageningen University & Research116
- Utrecht University59
- Leiden University Medical Center43
- Netherlands Institute of Ecology35
- Erasmus MC30
- Messenger RNA1→6
- Gene3→7
- DNA damage1→5
- Immune system1→5
- DNA repair1→4
- Gene1→5
- Biological pest control1→4
- Population1→4
- Production (economics)1→5
- Public health1→4
- Food security2→4
- Food safety2→4
Where biotechnology is researched across Netherlands
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.