Best Life Sciences Platforms and Tools Companies in North Carolina, United States
The 88 best Life Sciences Platforms and Tools companies in North Carolina, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Xilis.
Our analysis of 50 Life Sciences Platforms and Tools companies
$4.8b in tracked funding; 68% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Life Sciences Platforms and Tools companies in North Carolina
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Xilis Developer of drug discovery and precision therapy platform for oncology 53Patents top 21%Moat top 21%Innovation top 22%Funding top 26% All 9 signals ▾Patentstop 21% Moattop 21% Innovationtop 22% Fundingtop 26% Talentbottom 49% Marketbottom 46% Globalbottom 42% Techbottom 29% Newsbottom 22% Patents: 97 patents matched (strict assignee match) · 96 filings since 2022 vs 1 in 2017-21 Moat: Editorial + unicorn rating 8/10 · IP moat: 97 patents rank vs industry peers · Fliar Intelligence Index 53/100 | $89M | 14 mo ago | 72 | Hans Clevers Co-Founder | WordPressMySQLPHP+16 | Top 50M | 97 patents Microfluidic organoid droplet generation and component delivery for personalized medicine | — |
| 2 | Ribometrix Provider RNA-targeted drug discovery platform | $65M | 80 mo ago | 26 | — | — | — | 9 patents eIF4E inhibitor small molecules for oncology therapeutics | — |
| 3 | Microban Antimicrobial and odor control technologies for durable product protection and freshness | $65M | 256 mo ago | 141 | — | Craft CMSApple iCloud MailMicrosoft 365+31 | Top 5M | — | 1 launch · 1 partnership |
| 4 | Oriel Therapeutics Develops respiratory care drugs | $26M | 223 mo ago | — | Paul Atkins President & CEO | — | — | 148 patents Patents concentrated in health & consumer products | — |
| 5 | Cell Microsystems Developer of a technology to isolate and recover single cells for molecular analysis | $19M | 34 mo ago | 28 | — | WordPressMySQLPHP+33 | Top 10M | — | — |
| 6 | Precise Bio Developer of integrated 3D printing and tissue-engineering platform | $19M | 29 mo ago | 6 | Shay Soker Co-Founder & CSO | WordPressMySQLPHP+23 | Top 50M | — | — |
| 7 | KeraNetics Advanced biomaterials company focused on creating keratin-based products for use in areas of regenerative… | $14M | 111 mo ago | 14 | — | WordPressMySQLPHP+19 | Top 50M | 37 patents Keratin extraction and formulation for veterinary wound care and related biomaterial products. | — |
| 8 | Ascent Bio-Nano Technologies Innovating acoustofluidic technologies for research, diagnostics, and therapeutics with social impact | $14M | 9 mo ago | 2 | Lin Wang Co-Founder & CEO | — | — | — | — |
| 9 | LEAP Technologies Developer of automated systems for sample preparation and handling | $12M | 49 mo ago | 26 | Silverio Iacono CEO | — | — | 29 patents Microwave-based on‑site asphalt recycling and pavement production technology | — |
| 10 | Bioskryb Developer of a genome sequencing and amplification system | $12M | 77 mo ago | 21 21 → 40 (+90%) | Jay West Co-Founder & CEO | — | — | 8 patents High‑sensitivity nucleic‑acid amplification and single‑cell genomic analysis technologies | 1 launch |
| 11 | Inanovate Provider of multiplexed protein quantification platform for clinical diagnostics and research | $11M | 14 mo ago | 11 | David Ure Chairman & Founder | — | — | 30 patents High-throughput immunoassay platforms for serology and cancer biomarker detection | — |
| 12 | Isolere Bio Developer of bioprocessing reagents for purification and manufacturing of therapeutics | $7M | 52 mo ago | 18 | Joseph McMahon Co-Founder | Cart FunctionalitySquarespace CommerceSquarespace+15 | Top 50M | — | — |
| 13 | Gentris A provider of pharmacogenomic testing and biorepository services | $6M | 253 mo ago | 40 | — | — | — | 2 patents Generating reference controls for pharmacogenomic testing | — |
| 14 | Celldom Developer of single cell analysis device | $6M | 14 mo ago | 9 | Zachary Forbes Founder & CEO | — | — | 8 patents Microfluidic single-cell assay platforms for drug screening and barcoded particle analysis | — |
| 15 | Grid Therapeutics Developer of therapeutic antibodies | $6M | 66 mo ago | 4 | — | — | — | — | — |
| 16 | SoyMeds Biotech research: developing soybean seed-based therapeutics for disease treatment | $6M | 14 mo ago | 5 | — | — | — | 3 patents Plant-based recombinant protein production for edible vaccines and therapeutic proteins | — |
| 17 | Altis Biosystems Provider of invitro platform for drug testing | $5M | 6 mo ago | 29 | Scott Magness Co-Founder | WordPressMySQLPHP+18 | Top 50M | — | — |
| 18 | Tiamat Sciences Provider of data and result information for online lottery games | $5M | 39 mo ago | 10 | France Adil Founder & CEO | — | — | — | — |
| 19 | Affinergy Develops assays and research tools for specific biological systems | $5M | 34 mo ago | 193 | Peyton Anderson Founder & CEO | — | — | 97 patents Protein diagnostics, peptide-coated device drug delivery, and biomaterial tissue repair technologies. | — |
| 20 | Advanced Liquid Logic Bioassay protocols using digital microfluidics | $5M | 143 mo ago | 17 | Vamsee Pamula Co-Founder & ex-CTO | — | — | 617 patents Microfluidic droplet manipulation and magnetic bead handling for biochemical assays | — |
| 21 | Element Genomics Developer of epigenomic editing platform | $5M | 115 mo ago | 12 | John Oxaal Co-Founder | — | — | — | — |
| 22 | Phase Developer of 3D printing technology for microfluidics which is applicable to life sciences | $4M | 28 mo ago | — | Jeff Schultz Co-Founder | — | — | 78 patents Patents concentrated in mechanical & energy engineering | — |
| 23 | Protochips Electron microscopy products and analytical tools for studying nanoscale materials | $4M | 40 mo ago | 40 40 → 44 (+10%) | — | — | — | 183 patents Advanced electron microscopy instrumentation for drift correction, temperature control, and electrochemical analysis | — |
| 24 | Nirvana Sciences Provider and manufacturer of fluorescent dyes for medical diagnostic and imaging systems and tests | $4M | 60 mo ago | 12 | — | — | — | — | — |
| 25 | EpiCypher Provider of epigentic kits, reagents and assays for research purpose | $3M | 9 mo ago | 43 | — | Cart FunctionalityBigCommerceSearchanise+33 | Top 5M | 66 patents Chromatin profiling tools: nucleosome barcoding, modification quantification, and high‑throughput assays | 1 partnership |
| 26 | InnovaPrep Sample preparation tools for microbiology research | $3M | 6 mo ago | 37 37 → 23 (-38%) | Dave Alburty CEO | Cart FunctionalityShopifyVenmo+15 | Top 50M | 111 patents Disposable fluid-path devices for concentrating biological particles in liquids and aerosols | — |
| 27 | Phitonex Innovative flow cytometry solutions with NovaFluor dyes and conjugated antibodies | $2M | 80 mo ago | 11 | Chris Dwyer Co-Founder & CSO | — | — | 17 patents Nucleic‑acid bioconjugates enabling multiplexed single‑cell assays and signal amplification | — |
| 28 | Inhalon Biopharma Developing inhaled antibody treatments for acute respiratory infections, a clinical-stage biotechnology… | $2M | 10 mo ago | 8 | — | — | — | — | — |
| 29 | CellSolutions Cytology solutions: sample collection, preservation, slide preparation, and digital evaluation | $2M | 94 mo ago | 16 | Ernest Knesel CEO & President | — | — | 4 patents Automated cell sample preparation devices for biomedical analysis | — |
| 30 | Benanova Sustainable materials company creating nature-inspired colloid solutions for diverse markets | $2M | 23 mo ago | — | Alexander Richter Co-Founder | — | — | 8 patents Patents concentrated in health & consumer products | — |
| 31 | LigaTrap Technologies Innovating bioprocess purification technologies for complex biologics and advanced therapies | $2M | 100 mo ago | 9 | — | — | — | — | 2 partnerships |
| 32 | Enzerna Developer of novel molecular tools to modulate gene expression in any organism | $1M | 46 mo ago | 9 | — | — | — | — | — |
| 33 | Genoverde Provider of genetically engineering plants for higher carbon sequestration | $1M | 93 mo ago | — | Samuel Hazen Co-Founder & CSO | — | — | — | — |
| 34 | Neochromosome Genome-scale biological engineering enabling cell-based manufacturing and antibody discovery | $1M | 60 mo ago | 28 | — | — | — | 6 patents Patents concentrated in chemistry & materials | — |
| 35 | Xanofi Nano-fibres for healthcare applications | $825K | 169 mo ago | 9 | Miles Wright CEO & Board of Directors | — | — | 8 patents Nanofiber-based substrates and coatings for enhanced cell culture, hydrophobic surfaces, and dispersion technologies. | — |
| 36 | Falcon Therapeutics Developer of cell therapies to treat brain cancers | $700K | 108 mo ago | 5 | Susan Nichols CEO | — | — | — | — |
| 37 | Base4 Developer of RNA-modulating small molecule drugs for multiple diseases | $550K | 68 mo ago | — | Joshua Fairbank Founder & CEO | — | — | 14 patents Provides anti‑flare cookware and grill accessories such as pans, trivet and docking systems. | — |
| 38 | Entogenetics Provider of genetically engineered spider silk from silkworms for commercial-scale production | $540K | 155 mo ago | 11 | David Brigham Founder & CEO | — | — | 9 patents Recombinant spider silk protein production for biomaterial and textile applications | — |
| 39 | Creative Scientist Cell-based assay services accelerating drug discovery and development with scientific rigor | $499K | 94 mo ago | — | Alexander Kinev Founder & CEO | — | — | — | — |
| 40 | CasTag Developer of antibody kits for research purposes | $356K | 64 mo ago | 2 | — | — | — | — | — |
| 41 | Concentrx Pharmaceuticals Pharmaceutical company specializing in unit dose dry powder inhaler development | $308K | 128 mo ago | — | Gilbert Mott Founder & CEO & President | — | — | — | — |
| 42 | Redbud Labs Manufacturer of microfluidic platforms for biosensing and sample processing | $305K | 14 mo ago | 20 | — | — | — | 101 patents Patents concentrated in transport & manufacturing processes | — |
| 43 | Data Driven Bioscience Machine learning-enabled cancer genomics diagnostic kits | $301K | 17 mo ago | 4 | Sandeep Dave Founder | — | — | — | — |
Top 12 Life Sciences Platforms and Tools companies in North Carolina
#1
Series B · Durham, North Carolina · founded 2019 · 72 employees$89Mraised▾
Developer of drug discovery and precision therapy platform for oncology. The company has micro-organ sphere technologies which enable rapid diagnostics, personalized drug screening, and scalable patient-derived models for immuno-oncology drug discovery.
- Apr 2025Series B$19.4M
- Apr 2025Conventional Debt—
- Feb 2025Grant (prize money)$2.4M
- Jul 2022Series A$19M
#2
Funding Raised · Durham, North Carolina · founded 2011 · 2 employees$13.7Mraised▾
Innovating acoustofluidic technologies for research, diagnostics, and therapeutics with social impact. This biotech firm specializes in developing and commercializing acoustofluidic chips and instruments. The core competency lies in rapid prototype development for sample preparation, separation, manipulation of bioparticles, and bioanalysis. The company focuses on creating ready-to-manufacture prototypes with customer validation and collaborating with industry partners on customized product development and integration. The aim is to make a societal impact through innovative acoustofluidic technologies, offering solutions for research, diagnostic, and therapeutic applications.
- Aug 2025Grant (prize money)$1.7M
- Jun 2024Grant (prize money)$982.9K
- Aug 2019Grant (prize money)$2.7M
- Sep 2018Grant (prize money)$1.5M
#3
Seed · Durham, North Carolina · founded 2015 · 29 employees$5.4Mraised▾
Provider of invitro platform for drug testing. The company offers RepliGut a unique, stem cell-derived platform for studying many aspects of drug disposition including toxicity, metabolism, drug absorption, and efficacy.
- Nov 2025Grant (prize money)$1.8M
- Mar 2025Seed$2.1M
- Sep 2023Grant (prize money)$343.3K
- Jul 2023Grant (prize money)$1.8M
#4
Series A · Drexel, North Carolina · founded 2009 · 37 employees$2.6Mraised▾
Sample preparation tools for microbiology research. It provide tools for sample preparation in microbiology that increase sensitivity and enable a faster, easier, and more efficient means of delivering the most highly concentrated sample possible for downstream analyses. The company's products include concentrating pipettes, large volume concentrators, air samplers, and other custom solutions for special applications.
- Dec 2025Series A$100K
- Mar 2020Series A$500K
- Sep 2018Series A$2.1M
- Sep 2013Grant (prize money)$650.5K
#5
Series A · Chapel Hill, North Carolina · founded 2012 · 43 employees$3.4Mraised▾
Provider of epigentic kits, reagents and assays for research purpose. Its products include antibodies, cell extracts, histone peptide arrays, histone peptides, nucleosomes, peptide synthesis, and recombinant proteins. It also, offer Cutana cut and Run assays, which are an alternative to ChIP assays and offer advantages such as reduced cell input and diverse target profiling.
- Sep 2025Grant (prize money)$2M
- May 2025Grant (prize money)$2M
- Apr 2025Grant (prize money)$2.5M
- Feb 2025Grant (prize money)$1.4M
#6
Series C · Durham, North Carolina · founded 2006 · 11 employees$11.3Mraised▾
Provider of multiplexed protein quantification platform for clinical diagnostics and research. Its flagship product BioID uses a proprietary Longitudinal Assay Screening that functions as a real-time ELISA test to detect multiplexed proteins in patient samples. Its application is a test for breast cancer, which uses the BioID platform to detect 7 auto-antibodies associated with breast cancer.
- Mar 2025Series C$808K
- Nov 2024Series C$900K
- May 2024Series C$1.1M
- Dec 2023Series C$1.5M
#7
Funding Raised · Charlotte, North Carolina · founded 2005 · 5 employees$6.4Mraised▾
Biotech research: developing soybean seed-based therapeutics for disease treatment. The company focuses on biotechnology research to develop and validate soybean seed-based therapeutics. Their work aims to treat, prevent, cure, and diagnose diseases through innovative applications of soybean technology. They explore commercial applications and technology related to host systems. The company is dedicated to advancing healthcare solutions through plant-based research, contributing to the field of biotechnology with a focus on therapeutic development. This research has a social impact by potentially providing new and accessible treatments for various diseases.
- Apr 2025Grant (prize money)$573.5K
- Jan 2021Grant (prize money)$583.6K
- Sep 2016Grant (prize money)$1M
- Feb 2014Grant (prize money)$541.5K
#8
Seed · Morrisville, North Carolina · founded 2018 · 8 employees$2Mraised▾
Developing inhaled antibody treatments for acute respiratory infections, a clinical-stage biotechnology company focused on creating revolutionary treatments. They are rapidly advancing programs for multiple respiratory infections, addressing the unmet need for effective treatments against active infections directly in the lung. Their innovative inhaled drug platform aims to provide superior effectiveness and at-home convenience, simplifying respiratory care through a "test-to-treat" model. They are developing a pipeline of proprietary inhaled antibody treatments for respiratory syncytial virus, influenza, human metapneumovirus, and SARS-CoV-2. This biotechnology company is dedicated to improving patient outcomes through advanced therapeutic solutions.
- Aug 2025Grant (prize money)$2M
- May 2025Grant (prize money)$2M
- Apr 2025Grant (prize money)$2M
- Feb 2025Grant (prize money)$2M
#9
Seed · Durham, North Carolina · founded 2016 · 9 employees$6.5Mraised▾
Developer of single cell analysis device. The company offers CloneXplorer is the next-generation live single-cell assay platform that combines functional imaging and molecular readouts with integrated cell retrieval to identify and characterize rare cells that play critical roles in biological pathways and disease.
- Apr 2025Grant (prize money)$1.8M
- May 2024Grant (prize money)$938.6K
- Apr 2019Seed—
- Jan 2019Grant (prize money)$2M
#10
Series B · Winston-salem, North Carolina · founded 2015 · 6 employees$19Mraised▾
Developer of integrated 3D printing and tissue-engineering platform. The platform allows the production of repeatable bio-fabricated organs from the patient's own cells for cardiology, orthopedics, dermatology, and more. The company's lead product is 3D cardiac tissue “patch” for post-myocardial infarction (MI) implant to retrieve cardiac muscle viability and functionality.
- Jan 2024Series B$12M
- Jul 2022Seed—
- Feb 2022Conventional Debt$15.5M
- Series A$7M
#11
Series A · Chapel Hill, North Carolina · founded 2010 · 20 employees$305Kraised▾
Manufacturer of microfluidic platforms for biosensing and sample processing. The company's platform uses actuated surface-attached posts (ASAPs), which are micro-posts that bend in the presence of magnetic fields and are capable of fluid handling applications. ASAPs have a diameter less than that of a bacterium and can promote the manipulation of fluids, cells, and reagents. Its applications include life science research and the development of clinical diagnostics.
- Mar 2025Grant (prize money)$2.5M
- Mar 2025Grant (prize money)$2M
- 2022Grant (prize money)$3.3M
- 2021Grant (prize money)$1.3M
#12
Series B · Durham, North Carolina · founded 2009 · 28 employees$19.1Mraised▾
Developer of a technology to isolate and recover single cells for molecular analysis. The company's proprietary technology CellRaft AIR system allows to track the cells, grow colonies faster, and analyze with gentle sorting and isolation of your cells.
- Aug 2023Series B$6.5M
- Nov 2021Series A$12.6M
- Aug 2021Grant (prize money)$256.6K
- Mar 2021Grant (prize money)$2.1M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Life Sciences Platforms and Tools coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Bioinformatics is moving in the United States
A read on the academic research around Bioinformatics — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 13,110 United States-affiliated papers.
- Harvard University633
- Broad Institute433
- Howard Hughes Medical Institute318
- Stanford University287
- Johns Hopkins University287
- Gene83→532
- Transcriptome25→436
- Genome117→419
- Disease6→218
- Immune system11→219
- Disease17→407
- Immune system4→266
- Gene38→281
- Transcriptome13→238
- Biomarker2→208
- Disease27→311
- Immune system6→152
- Cancer17→130
- Clinical trial4→111
- Biomarker2→92
Where bioinformatics is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing bioinformatics patents in the United States
United States bioinformatics patent filing is accelerating — 246 filings from 64 assignees (2016–2025), led by Edico Genome, Illumina, UNIV Washington; annual filings 22→23.
- Edico Genome129
- Illumina60
- UNIV Washington18
- Nantomics9
- Genomsys7
- Baluch Mohamed Khoso7
- Microsoft6
- Contamination Source Identificat6
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.