Best Healthcare Companies in North Carolina, United States
The 827 best Healthcare companies in North Carolina, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: PPD.
Ranked: Best Healthcare companies in North Carolina
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | PPD CRO providing diversified clinical development services 87Funding top 18%Fin. health top 19%Market top 23%Moat top 34% All 8 signals ▾Fundingtop 18% Fin. healthtop 19% Markettop 23% Moattop 34% Techtop 38% Growthbottom 48% Globalbottom 46% Newsbottom 35% Funding: Raised $1.0B across 5 rounds · 5 rounds over 3 yrs (1.7/yr) Fin. health: Revenue ~$4.7B (FY2021) · Net margin 10.7% rank vs industry peers · Fliar Intelligence Index 87/100 | $1.0B | 32 mo ago | 1,530 | 1985 | — | WordPress Block EditorWordPressMySQL+27 | — | — |
| 2 | Caidya CRO focused on clinical development for phases II & III clinical trials and regulatory affair services 50Funding top 20%Tech top 48%Growth bottom 45%Market bottom 44% All 7 signals ▾Fundingtop 20% Techtop 48% Growthbottom 45% Marketbottom 44% Moatbottom 38% Globalbottom 37% Newsbottom 21% Funding: Raised $373M across 5 rounds · 5 rounds over 10 yrs (0.5/yr) Tech: 25 technologies across 4/8 capability areas · Cloud: Cloudflare rank vs industry peers · Fliar Intelligence Index 50/100 | $373M | 17 mo ago | 351 351 → 748 (+113%) | 2003 | — | WordPressMySQLPHP+22 | — | 1 partnership · 2 awards |
| 3 | Asymchem CDMO providing comprehensive pharmaceutical development and manufacturing solutions globally | $331M | 76 mo ago | 48 | 1995 | — | Apple iCloud MailTypeScriptSalesforce+14 | — | — |
| 4 | Avista Pharma Leading hosting automation software providing web server and website management tools | $252M | — | 330 | 2015 | — | — | — | — |
| 5 | UpStream Provides wellness services | $185M | 42 mo ago | 300 | 2019 | — | — | — | — |
| 6 | Patheon Global CDMO providing integrated drug development, clinical trials, and manufacturing services | $141M | 53 mo ago | 9,000 | 1974 | Doug Sprague Founder | Adobe Experience ManagerJavaMicrosoft ASP.NET+14 | 10 patents pH‑dependent solid dosage forms for controlled release of ionizable poorly soluble drugs | — |
| 7 | Abound Health Provides rehabilitation services 62Funding top 28%Growth top 35%Market top 44%Product top 47% All 7 signals ▾Fundingtop 28% Growthtop 35% Markettop 44% Producttop 47% Talentbottom 49% Techbottom 42% Globalbottom 32% Funding: Raised $140M across 1 rounds · 1 rounds over 2 yrs (0.5/yr) Growth: Headcount 898 → 1,245 (+39%) across vintages rank vs industry peers · Fliar Intelligence Index 62/100 | $140M | 25 mo ago | 1,245 | 1997 | Dennis Lally CEO | WordPressApple iCloud MailMicrosoft 365+21 | — | — |
| 8 | Petfolk Provider of veterinary surgery, dental care, and behavioral training services | $116M | 20 mo ago | 101 | 2015 | Michael Wystrach Co-Founder & Co-CEO | ContentfulSentryApple iCloud Mail+33 | — | — |
| 9 | Pathalys Provider of CKD biotherapeutics development services | $105M | 21 mo ago | 8 | 2021 | Neal Fowler CEO | — | — | — |
| 10 | Roanoke Chowan Community Health Center Provider of primary and preventive healthcare services | $96M | 12 mo ago | 112 | 2005 | — | JoomlaApple iCloud MailPHP+13 | — | 4 job openings |
| 11 | High Country Community Health Provider of integrated medical and dental services, including behavioral health and nutrition | $95M | 11 mo ago | 67 | 2013 | — | WixSentryEnvoy+15 | — | — |
| 12 | ADDYI Provider of patients medical informations | $94M | 101 mo ago | 48 | 2010 | — | WordPressMySQLPHP+33 | — | — |
| 13 | Gaia Herbs Gaia Herbs is a leading grower and producer of Certified Organic (COG) herbs and herbal products | $71M | 47 mo ago | 253 253 → 179 (-29%) | 1987 | — | Cart FunctionalityShopifySentry+41 | 3 patents Botanical anti-inflammatory compounds derived from Echinacea for therapeutic formulations | — |
| 14 | Rho Full and functional service CRO offering clinical development services 57Funding top 35%Growth top 35%News top 40%Tech top 45% All 7 signals ▾Fundingtop 35% Growthtop 35% Newstop 40% Techtop 45% Markettop 49% Globalbottom 37% Productbottom 36% Funding: Raised $67.5M across 9 rounds · 9 rounds over 12 yrs (0.8/yr) Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 57/100 | $67M | 13 mo ago | 859 | 1984 | — | WordPressApple iCloud MailMySQL+24 | — | — |
| 15 | Centice Computational sensor technology | $52M | 146 mo ago | 12 | 2004 | — | — | — | — |
| 16 | Humaneva Group Provider of clinical research data services for oncology & other therapeutic areas | $50M | 20 mo ago | — | 2014 | Tomasz Dabrowski Co-Founder & CEO | AzurePriority HintsPreact+6 | — | — |
| 17 | Belhaven Biopharma Developer of needle-free nasal spray for anaphylaxis and severe allergic reactions | $44M | 9 mo ago | 4 | 2020 | — | — | 27 patents Dry powder epinephrine formulations for inhalation and intranasal delivery devices | — |
| 18 | Javara Research Integrating clinical research at the point of care for better outcomes 50Funding top 31%Growth top 35%Tech top 43%Moat top 48% All 8 signals ▾Fundingtop 31% Growthtop 35% Techtop 43% Moattop 48% Talentbottom 49% Marketbottom 41% Globalbottom 29% Newsbottom 21% Funding: Raised $40.0M across 5 rounds · 5 rounds over 7 yrs (0.7/yr) Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 50/100 | $40M | 13 mo ago | 233 | 2018 | Jennifer Byrne CEO | WordPressApple iCloud MailMicrosoft 365+26 | — | 1 award |
| 19 | Inceptor CDMO offering services for cell and gene therapy products 7Funding top 47%Moat bottom 42%Global bottom 35%Market bottom 34% All 7 signals ▾Fundingtop 47% Moatbottom 42% Globalbottom 35% Marketbottom 34% Patentsbottom 31% Newsbottom 21% Innovationbottom 4% Funding: Raised $37.7M across 3 rounds · 3 rounds over 4 yrs (0.8/yr) Moat: Editorial + unicorn rating 1/10 · IP moat: 2 patents rank vs industry peers · Fliar Intelligence Index 7/100 | $38M | 17 mo ago | 69 | 2020 | — | — | 2 patents Accelerating web page delivery and enriching data indexing for e‑commerce platforms | — |
| 20 | Veritas Collaborative Chain of mental and behavioral therapy centers | $27M | 73 mo ago | 550 | 2012 | — | — | — | — |
| 21 | HPTN Healthcare association involved in HIV prevention trials | $21M | 66 mo ago | — | 2000 | — | DrupalPHPPlatform.sh+4 | — | — |
| 22 | KBI Biopharma Provider of protein formulation, process & cell line development, and cGMP services | $21M | 202 mo ago | 1,243 1,243 → 1,686 (+36%) | 1996 | — | HubSpot CMS HubApple iCloud MailMicrosoft 365+26 | 24 patents Non‑chromatographic protein purification using steric exclusion and charge neutralization; fluidized‑bed particle processing. | 1 launch · 1 partnership |
| 23 | Open Book Extracts Manufacturer and supplier of plant-based cannabinoid products | $20M | 19 mo ago | 58 | 2019 | Scott Thorn Co-Founder and CSO/COO | Cart FunctionalityWooCommerceWordPress+28 | — | — |
| 24 | Novant Health Chain of multispeciality hospitals 74Tech top 23%Customers top 30%Market top 35%Funding top 42% All 9 signals ▾Techtop 23% Customerstop 30% Markettop 35% Fundingtop 42% Growthtop 50% Productbottom 43% Moatbottom 38% Globalbottom 37% Newsbottom 27% Tech: 51 technologies across 7/8 capability areas · Cloud: Azure, Cloudflare Customers: Play-Store rating 4.56★ across 636 ratings (2 apps) · Review volume +9% in 6 mo rank vs industry peers · Fliar Intelligence Index 74/100 | $19M | 11 mo ago | 29,747 | 1997 | — | Apple iCloud MailMicrosoft 365TypeScript+21 | — | — |
| 25 | Collaborations Pharmaceuticals AI-driven drug discovery for rare, neglected diseases, and toxicology solutions | $18M | 27 mo ago | 9 | 2014 | — | UbuntuNginxMicrosoft 365 | — | — |
| 26 | NightHawk Biosciences Fully integrated biopharmaceutical company | $17M | 32 mo ago | 29 | 2008 | — | — | — | — |
| 27 | Parion Sciences Developing therapies to restore lung mucosal defense for respiratory diseases | $12M | 10 mo ago | 13 | 2000 | Paul Boucher CEO and President | — | 546 patents Respiratory therapeutics targeting ENaC inhibition and mucolytic agents for airway clearance | — |
| 28 | Scion NeuroStim Manufacturer of neuromodulation medical devices | $10M | 32 mo ago | 12 | 2007 | — | — | 108 patents Advanced neurostimulation and vestibular stimulation devices with packet/envelope modulation | — |
| 29 | EmVenio Research Provider of clinical trials support, patients engagement, and research services | $9M | 42 mo ago | 79 | 2020 | Keith Henthorne CEO | WordPressApple iCloud MailMicrosoft 365+29 | — | — |
| 30 | URO-1 Innovating prostate biopsy instruments for accurate diagnosis and improved patient outcomes | $8M | 53 mo ago | 4 | 2017 | — | — | — | — |
| 31 | Isolere Bio Developer of bioprocessing reagents for purification and manufacturing of therapeutics | $7M | 52 mo ago | 18 | 2017 | Joseph McMahon Co-Founder | Cart FunctionalitySquarespace CommerceSquarespace+15 | — | — |
| 32 | Pulvinar Neuro Developer of drugs for neuroscience research services | $7M | 15 mo ago | 5 | 2016 | — | — | — | — |
| 33 | Exela Pharma Manufacturer of sterile injectable pharmaceutical products and CDMO services 48Innovation top 20%Product top 30%Growth top 40%Funding top 43% All 8 signals ▾Innovationtop 20% Producttop 30% Growthtop 40% Fundingtop 43% Talentbottom 49% Marketbottom 37% Globalbottom 32% Techbottom 31% Innovation: 8 product lines Product: 8 distinct product lines · Company stage: Series B rank vs industry peers · Fliar Intelligence Index 48/100 | $7M | 8 mo ago | 205 205 → 339 (+65%) | 2005 | Phanesh Koneru Co-Founder & CEO | WordPressMySQLPHP+17 | — | 2 job openings · 1 award |
| 34 | QATCH Technologies CRO focused on providing early stage drug development services | $6M | 15 mo ago | 6 | 2016 | — | — | — | 1 launch |
| 35 | Clinical Trial Research Network of research sites providing clinical trial management services 29Funding top 41%Talent bottom 49%Global bottom 33% All 3 signals ▾Fundingtop 41% Talentbottom 49% Globalbottom 33% Funding: Raised $5.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 29/100 | $5M | 6 mo ago | — | 2025 | Adarsh Karanth Founder Director | — | — | — |
| 36 | Trillium Health Resources Provider of services for mental health, substance use, and disabilities 50Innovation top 20%Growth top 35%Product top 46%Market bottom 48% All 7 signals ▾Innovationtop 20% Growthtop 35% Producttop 46% Marketbottom 48% Fundingbottom 41% Globalbottom 34% Techbottom 21% Innovation: 5 product lines Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 50/100 | $5M | 12 mo ago | 283 | 1999 | — | DrupalPHPGoogle Font API+5 | — | 1 job opening · 1 partnership |
| 37 | Piedmont Stone Center Mobile lithotripsy services for non-surgical kidney stone treatment | $3M | 29 mo ago | 22 | 2005 | — | — | — | — |
| 38 | Bionic Health Standalone general clinic | $3M | 38 mo ago | 11 | 2022 | Robbie Allen Co-Founder & CEO | WebflowReactKlaviyo Forms+22 | — | — |
| 39 | Lamassu Pharma Provider of market research and clinical development & testing services | $3M | 27 mo ago | 3 | 2018 | Greg Palmer Co-Founder & CSO | — | — | — |
| 40 | VQ Biomedical Developer of intravascular oxygenation catheter for respiratory failure in hospitals | $2M | 22 mo ago | — | 2023 | Marc Deshusses Co-Founder and Principal Scientist/Engineer | — | — | — |
| 41 | Sciome Provider of software development services for biopharma sector | $2M | 33 mo ago | — | 2010 | — | — | 9 patents AI-driven text extraction from unstructured documents and recall estimation for systematic reviews | — |
| 42 | IMR Institute For Medical Research conducts and supports research and educational activities to enhance health. | $1M | 15 mo ago | 107 | 1989 | — | WordPressMySQLPHP+9 | — | — |
| 43 | Quasar Health Solutions Provider of healthcare solutions with a focus on prevention and well-being, offering a range of medical… | $1M | 24 mo ago | — | 2023 | Madeline Sol Co-CEO | — | — | — |
| 44 | ZealCare | $805K | 14 mo ago | 10 | 2020 | Ralph Snyderman Founder And Board Member | — | — | — |
| 45 | Wellzesta Provider of home healthcare services | $750K | 24 mo ago | 18 | 2014 | — | SentryZendeskTypeScript+24 | — | 1 launch |
| 46 | ECU Health Health systems | $694K | 13 mo ago | 1,827 | 1992 | — | WordPressApple iCloud MailAlgolia+22 | — | — |
| 47 | Balanced pHarma Manufacturer and development of anesthetic drugs | $481K | 18 mo ago | 5 | 2018 | John Keadle Founder & CEO | — | — | — |
| 48 | Scope Anesthesia Provider of anesthesia services | $464K | 17 mo ago | — | 2018 | Thomas Wherry Founder & CEO | — | — | — |
| 49 | Tripleswitch Brewing Retailer of non-alcoholic beer infused with THC and CBD | $125K | 11 mo ago | — | 2024 | Paul Pirner Co-Founder/Partner | Cart FunctionalityShopifyEasyGift+20 | — | — |
| 50 | EmergeOrtho Chain of orthopedic clinics | $114K | 17 mo ago | — | 2016 | Kyle Raygor CEO | WordPressSentryApple iCloud Mail+30 | — | — |
Top 12 Healthcare companies in North Carolina
#1
Funding Raised · Boone, North Carolina · founded 2013 · 67 employees$94.6Mraised▾
Provider of integrated medical and dental services, including behavioral health and nutrition. It offers primary care for all ages, from pediatrics to geriatrics. Dental services encompass preventative care, restorative procedures, and oral surgery. Behavioral health services are available both in-person and online. Nutritional guidance and lifestyle planning are also provided. The organization assists patients with accessing financial assistance programs, such as sliding fee scales and prescription drug discounts. Support services include patient advocacy and resource coordination to ensure access to necessary social and medical resources
- Jul 2025Grant (prize money)$15.7M
- 2025Grant (prize money)$1.1M
- Jun 2025Grant (prize money)$3M
- May 2025Grant (prize money)$74K
#2
Series C · Morrisville, North Carolina · founded 2003 · 351 employees$373Mraised▾
CRO focused on clinical development for phases II & III clinical trials and regulatory affair services
- Jan 2025PE$165M
- Jul 2021Series C$50M
- Dec 2020Series C$100M
- Oct 2019Series B$50M
#3
Funding Raised · Ahoskie, North Carolina · founded 2005 · 112 employees$96.2Mraised▾
Provider of primary and preventive healthcare services, including pediatrics, dental care, mental health, and substance abuse treatment. It offers services in a medical home setting, ensuring accessible and affordable care. The organization provides complete preventive and primary health care for families. A pharmacy and other supplemental services are also available. No one is denied access due to inability to pay
- May 2025Grant (prize money)$31K
- Apr 2025Grant (prize money)$589K
- Mar 2025Grant (prize money)$16.4M
- Feb 2025Grant (prize money)$425.3K
#4
Series C · Raleigh, North Carolina · founded 2020 · 4 employees$44Mraised▾
Developer of needle-free nasal spray for anaphylaxis and severe allergic reactions. The company focuses on creating accessible and user-friendly emergency medications. It develops dry powder nasal formulations to improve drug absorption and simplify emergency use. The goal is to provide temperature-stable, pain-free options for allergy emergencies.
- Aug 2025Series C$32.3M
- Jan 2025Seed$11M
- Feb 2023Conventional Debt$500K
- Jul 2021Conventional Debt$250K
#5
Funding Raised · Chapel Hill, North Carolina · founded 1984 · 859 employees$67.5Mraised▾
Rho offers contract research services for Phase I - IV trials, post-approval phases, regulatory submissions, and trial rescue. They use the proprietary platforms of Medidata, Oracle, and Medrio for clinical trial management. Their clinical trial service portfolio includes Biostatistics and Statistical Programming, Clinical Data Management, Clinical Operations and Monitoring, Clinical Project Management, Data Standards, Medical Monitoring, Product Safety, Quality Assurance, Regulatory Operations, Re and Medical Writing. Therapeutic areas they cater to are ADHD, Analgesia, CNS, Dental, Hematology, Ophthalmology, Psychiatric Disorders, Respiratory. They are currently engaged in over 23 federal projects and have signed contracts for clinical development with various US Federal Agencies. They also offer their services on an FSP basis for biostatistics and statistical programming, data standards and CDISC, Data management, and Regulatory medical writing.
- May 2025Grant (prize money)$28.2M
- Apr 2025Grant (prize money)$28.4M
- Feb 2021Grant (prize money)$368.9K
- Apr 2014Grant (prize money)—
#6
Series B · Winston-salem, North Carolina · founded 2018 · 233 employees$40Mraised▾
Integrating clinical research at the point of care for better outcomes. This organization pioneers Clinical Research as a Care Option (CRAACO), connecting patients with clinical trials through trusted physicians and healthcare partners. The model unlocks access to broader, more diverse populations, driving faster enrollment, stronger retention, and richer data. By streamlining operations and centralizing resources, they aim to reduce the drug development time cycle and improve patient care. As an Integrated Research Organization (IRO), they provide staff, training, and infrastructure needed to conduct clinical trials and drive innovation. They focus on diversity, equity, and inclusion, fostering greater innovation and improving communication and care. The organization partners with biopharma, biotech, and CRO companies to deliver high-quality data from diverse patient populations, enhancing patient care through in-house clinical research. They offer services to healthcare organizations, biopharmaceutical companies, and contract research organizations (CROs).
- May 2025Series B$6.6M
- Nov 2023Conventional Debt$9.4M
- Apr 2022Series B$30M
- Aug 2020Series A$4.6M
#7
Funding Raised · Durham, North Carolina · founded 2000 · 13 employees$12Mraised▾
Developing therapies to restore lung mucosal defense for respiratory diseases. The company focuses on science-driven technologies targeting respiratory illnesses caused by defective mucosal host defense. Their pipeline includes ENAC PULMONARY, tPAD, and Mucolytic Agents, progressing through research and clinical trials. They aim to commercialize innovative products addressing conditions like cystic fibrosis and Primary Ciliary Dyskinesia. The company fosters partnerships and is dedicated to advancing respiratory medicine through research and development. They are not a tech company, SaaS, Software, or Cloud Based company. They are a B2B company.
- Aug 2025Grant (prize money)$2.3M
- May 2024Grant (prize money)$295.7K
- Jan 2020Grant (prize money)$274.2K
- Sep 2014Grant (prize money)$3M
#8
Funding Raised · Charlotte, North Carolina · founded 1997 · 29747 employees$18.8Mraised▾
Chain of multispeciality hospitals
- Jul 2025Grant (prize money)$2.2M
- 2025Grant (prize money)$115.6K
- Apr 2025Grant (prize money)$2.2M
- 2024Grant (prize money)$499.2K
#9
Late Stage · Research Triangle Park, North Carolina · founded 2025$5Mraised▾
Network of research sites providing clinical trial management services. The organization offers site management for clinical trials across multiple therapeutic areas. These areas include behavioral health, central nervous system, respiratory, pulmonary, internal medicine, gastrointestinal, nephrology, and ophthalmology. The organization aims to improve clinical trial efficiency through technology and collaboration with healthcare providers.
- Nov 2025PE$5M
#10
Series B · Lenoir, North Carolina · founded 2005 · 205 employees$6.7Mraised▾
Manufacturer of sterile injectable pharmaceutical products and CDMO services. This entity develops and manufactures both proprietary and generic sterile injectables. Its operations encompass the entire pharmaceutical lifecycle, from research and development to finished drug product manufacturing and distribution. Services include contract development and manufacturing, leveraging expertise in liquid vials, IV bags, lyophilized vials, and pre-filled syringes. The company also offers a range of regulatory support services.
- Sep 2025Grant (prize money)$28.3M
- Sep 2021Series B—
- Aug 2015Series A$419.8K
- Jul 2013Conventional Debt$1M
#11
Series C · Charlotte, North Carolina · founded 2015 · 101 employees$116Mraised▾
Provider of veterinary surgery, dental care, and behavioral training services
- Oct 2024Series C$36M
- Jul 2023Series B$40M
- Aug 2022Series A$40M
#12
Series A · Raleigh, North Carolina · founded 2020 · 69 employees$37.7Mraised▾
CDMO offering services for cell and gene therapy products
- Jan 2025Series A$21M
- Oct 2022Conventional Debt$15.9M
- Mar 2022Series A$37.7M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Healthcare coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.