Best HealthTech Companies in North Carolina, United States
The 501 best HealthTech companies in North Carolina, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: GenetronHealth.
Our analysis of 305 HealthTech companies
$32.1b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best HealthTech companies in North Carolina
| # | Company | Disclosed funding | Last round | Stage | Employees | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | GenetronHealth Provider of services in the development of precision medicine tools for cancer treatment | $191M | 78 mo ago | Public | 993 | Sizhen Wang Co-Founder & CEO | BootstrapNginxSwiper+6 | — | 1 launch |
| 2 | Well Provider of personalized health improvement plans with financial incentives and concierge support | $178M | 14 mo ago | Series B | 182 | David Werry Co-founder | WordPressApple iCloud MailGoogle Workspace+24 | 402 patents Electric-powered hydraulic fracturing equipment and power management systems | — |
| 3 | AccessOne Patient financing solutions, offering online access and payment options | $150M | 96 mo ago | Funding Raised | 220 | Russell Salton Founder | JavaWindows ServerMicrosoft ASP.NET+19 | — | — |
| 4 | MedShift Developer of software solutions for manufacturers and healthcare provider businesses | $116M | 37 mo ago | Series B | 39 | Brittani Rotunda Phillips Co-Founder / Board Advisor | Cart FunctionalityShopifyApple iCloud Mail+33 | — | 2 internships · 1 launch · 1 award |
| 5 | Bardy Diagnostics Medical technology company providing solutions for healthcare providers, caregivers, and patients | $83M | 75 mo ago | Acquired | 229 | — | WordPressMySQLMariaDB+27 | 380 patents Wearable cardiac monitoring systems: ECG patches, ambulatory data streaming, and rechargeable implants | — |
| 6 | Studycast A cloud PACS and echocardiogram reporting software solution for radiology, cardiology, and women's health. | $80M | 17 mo ago | Series C | 46 | — | WordPressMySQLPHP+23 | — | — |
| 7 | K4Connect Integrated technology solutions enhancing senior living community experiences and operational efficiency 53Funding top 24%News top 31%Moat top 32%Product top 37% All 12 signals ▾Fundingtop 24% Newstop 31% Moattop 32% Producttop 37% Talenttop 37% Growthtop 38% Patentstop 41% Innovationtop 43% Marketbottom 44% Globalbottom 40% Techbottom 36% Customersbottom 36% Funding: Raised $51.3M across 8 rounds · 8 rounds over 11 yrs (0.7/yr) News: 5 BI events in 12 mo (of 25 tracked, 5 types) · Top themes: Leadership rank vs industry peers · Fliar Intelligence Index 53/100 | $51M | 14 mo ago | Series C | 48 48 → 39 (-19%) | Jonathan Gould Cofounder | — | 70 patents Smart home automation integrating health analytics and dual-protocol network communication. | — |
| 8 | Spencer Health Solutions Provider of device and app for medication adherence | $45M | 20 mo ago | Series D | 76 | Tom Rhoads Founder & CEO | WordPressApple iCloud MailMicrosoft 365+24 | — | — |
| 9 | Nufabrx Provider of a wearable fabric with therapeutic value for pian managmenet | $43M | 56 mo ago | Acquired | 32 | Jordan Schindler Founder & CEO | Cart FunctionalityShopifyElement UI+33 | — | — |
| 10 | Medicom Web application for the medical industry that provides administrative task management tool | $42M | 22 mo ago | Series B | 15 | — | — | — | — |
| 11 | Valencell Developer of based medical sensors for monitoring body vitals | $38M | 76 mo ago | Series E | 34 | Steven Leboeuf President & Co-Founder | Tailwind CSSVue.jsAstro+13 | 418 patents Wearable photoplethysmography sensors for real-time health metrics estimation | — |
| 12 | Sleepme Provider of sleep management systems | $37M | 52 mo ago | Series C | 21 21 → 23 (+10%) | — | ShopifySentryZendesk+43 | 31 patents Adjustable thermal/acoustic bed zones for stress reduction, sleep enhancement, and weight loss | 1 expansion |
| 13 | Validic Provider of a single platform which aggregates data from multiple health device connections | $32M | 43 mo ago | Series B | 128 | — | SentryAtlassian StatuspageBackbone.js+15 | 6 patents Secure health data authentication and optical digit reading of segmented displays | — |
| 14 | PatientPay Provider of payment solutions for healthcare organizations and their patients | $31M | 56 mo ago | Series C | 22 | Tom Furr Founder & CEO | Cart FunctionalitySquarespace CommerceSquarespace+18 | 2 patents Healthcare payment processing systems for installment billing | 1 partnership |
| 15 | Advanced Animal Diagnostics On-farm diagnostics for precise animal care, increased profits, and reduced antibiotics | $29M | 61 mo ago | Series C | 16 | — | Cart FunctionalityWixSentry+14 | 72 patents Rapid mobile diagnostic tools for animal infection detection and survivability assessment | — |
| 16 | Topography Health The company provides a full-stack clinical trials platform for community physicians | $28M | 52 mo ago | Series A | 12 | Andrew Kirchner Co-Founder | — | — | — |
| 17 | Codetta Online platform for analyzing omics clinical data | $27M | 24 mo ago | Series A | 21 | — | — | — | — |
| 18 | Portray Developer of intraoral 3D Tomosynthesis dental X-ray system | $25M | 35 mo ago | Series B | 19 | David Vance CEO | — | — | — |
| 19 | Reactive Biosciences Developer of boron-based medicines for various disease conditions | $23M | 16 mo ago | Series A | — | Julie Grant CEO | — | — | — |
| 20 | Ten63 Developer of therapeutics for undruggable targets 21Talent top 28%Funding top 32%Moat top 35%News top 44% All 7 signals ▾Talenttop 28% Fundingtop 32% Moattop 35% Newstop 44% Globalbottom 39% Techbottom 26% Marketbottom 24% Talent: 4 named leaders on record · 4 C-suite/founder profiles curated Funding: Raised $18.3M across 3 rounds · 3 rounds over 7 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 21/100 | $18M | 3 mo ago | Series A | 10 | Mark Hallen Co-Founder & CTO | WordPressMySQLPHP+13 | — | — |
| 21 | 8 Health Provider of a clinical best practices implementation platform for healthcare teams | $18M | 10 mo ago | Series A | — | Galia Schwarz Cofounder & CEO | WordPressHubSpot CMS HubBugHerd+23 | 9,824 patents Cell-based immunotherapies, targeted imaging agents, and regenerative medicine technologies. | 8 job openings |
| 22 | Clinetic Provider of data analysis and diagnostic tools for clinical trial professionals | $11M | 34 mo ago | Acquired | 17 | Erich Huang Md Founder | — | — | — |
| 23 | Keona Health Cloud-based CRM platform for healthcare providers | $10M | 35 mo ago | Series A | 25 | Stephen Dean Co-Founder & COO | WordPressHubSpot CMS HubMySQL+36 | — | — |
| 24 | Quinsite Provider of healthcare data analytics software to physician practices | $8M | 37 mo ago | Series A | 3 | Jenny Maze Co-Founder | — | — | 1 job opening · 1 partnership |
| 25 | Ventricle Health Ventricle Health is a high-growth virtual healthcare startup that provides digital care focused on heart… | $8M | 32 mo ago | Seed | — | Sean O’Donnell CEO | Apple iCloud MailGoogle WorkspaceAmazon Web Services+7 | — | — |
| 26 | Biospatial Cloud-based platform to provide information about health events | $8M | 28 mo ago | Series A | 12 | Jonathan Woodworth Co-Founder & COO | — | — | — |
| 27 | Lindy Biosciences Developer of formulation technology for bio-therapeutics drug delivery | $7M | 27 mo ago | Series B | 4 | — | — | — | — |
| 28 | Avicenna Provider of drug development solutions | $6M | 23 mo ago | Funding Raised | — | Pieter Burger Co-Founder | — | — | — |
| 29 | Siftwell AI-based data-driven solutions for healthcare payors | $6M | 8 mo ago | Seed | 6 | Eben Esterhuizen Co-Founder & CTO | — | — | — |
| 30 | Truentity Health Medication management tool for healthcare professionals | $5M | 4 mo ago | Series A | 12 | Mike Desai Co-Founder & CEO | — | — | — |
| 31 | Gradient Health AI-based medical image management tool | $5M | 14 mo ago | Seed | — | Joshua Miller Chief Executive Officer | TurbopackEmotionApple iCloud Mail+21 | — | — |
| 32 | Vega Health Provider of AI solutions for healthcare organizations to improve patient care | $5M | 10 mo ago | Series A | — | Mark Sendak Co-Founder and CEO | — | — | 2 partnerships |
| 33 | Amissa Developer of a wearable-based data collection solutions for the prediction, early identification, and… | $5M | 10 mo ago | Funding Raised | 7 | Jon Corkey Founder & CEO | ContentfulTurbopackNode.js+12 | — | — |
| 34 | RevelAi Health Provider of generative AI platform for value-based specialty care for health systems and payors | $4M | 14 mo ago | Seed | — | Kamran Khan Co-Founder & CEO | Squarespace CommerceCart FunctionalitySquarespace+25 | — | — |
| 35 | Alleviate Health Provider of AI-powered platform for clinical research participant recruitment workflows | $4M | 8 mo ago | Seed | — | Saathvik Boompelli Co-Founder | — | — | — |
| 36 | Greenlight Health Provider of software solutions to store multiple health data | $4M | 18 mo ago | Series A | 21 | Stephen Malik Founder | WordPressMySQLPHP+29 | — | — |
| 37 | OrbitalRX Provider of an online platform for pharmacists to manage drug shortages and supply chain management | $4M | 9 mo ago | Series A | 10 | — | — | — | — |
| 38 | Liine Platform offering marketing solutions for healthcare organizations | $4M | 18 mo ago | Series A | 30 | — | — | — | 1 launch · 1 award |
| 39 | cbdMD Provider of cannabis products | $3M | 5 mo ago | Public | 52 52 → 86 (+65%) | Scott Coffman Founder & CEO | Cart FunctionalityShopifyTypeScript+51 | 2 patents Formulating stable cannabinoid-based pharmaceutical compositions for therapeutic applications. | — |
| 40 | XanderGlasses Developer of smart glasses providing real-time captioning | $3M | 22 mo ago | Seed | — | Marilyn Westner Co-founder and Chief Experience Officer | HubSpot CMS HubApple iCloud MailYouTube+14 | 4 patents Real-time speech-to-text transcription integrated into augmented-reality eyeglass devices. | — |
| 41 | Clinware Developer of software automating healthcare reimbursement and patient referral processes | $2M | 13 mo ago | Seed | — | Cory Evans Founder & CEO | Node.jsZohoTailwind CSS+7 | — | 1 launch |
| 42 | mPATH Cloud-based program to healthcare organizations for a preventive care service | $2M | 11 mo ago | Seed | 4 | David Miller Co-Founder & CEO | WordPressMySQLPHP+14 | — | — |
| 43 | Polymer Braille Provider of braille display technology | $1M | 14 mo ago | Funding Raised | — | Peichun Yang Co-Founder | — | — | — |
| 44 | VERINETICS Supply chain solutions for the pharmaceutical industry to combat counterfeit products | $1M | 15 mo ago | Seed | 8 | Tom Mercolino CEO & President | — | 14 patents Automated secure drug dispensing and remote medication management systems | — |
| 45 | ForesightCares AI-based elderly care coordination platform for professionals | $1M | 12 mo ago | Funding Raised | — | Hamed Tabkhi Co-Founder / CTO | — | 2 patents AI-driven mobility assessment tools for medical rehabilitation and patient monitoring | 1 launch · 1 award |
| 46 | DentalHQ Online dental insurance platform for individuals and businesses | $835K | 14 mo ago | Seed | 17 | Brett Wells Founder | WordPressShowitMySQL+26 | — | — |
| 47 | Social Cascade Provider of social media patient education solutions. This company offers a platform that allows healthcare… | $379K | 15 mo ago | Seed | 10 | Philippe Sabourin Co-Founder | — | — | 1 launch |
Top 12 HealthTech companies in North Carolina
#1
Series A · Durham, North Carolina · founded 2019 · 10 employees$18.3Mraised▾
Ten63 is a developer of drugs that target undruggable protein targets. The company is developing therapeutics through its platform called COPPER that uses proprietary AI technology and physical models to explore the protein chemical space and screen a large dataset of molecules to identify binding sites.
- Feb 2026Series A—
- May 2023Series A$15.9M
- Jan 2021Seed$2.1M
- 2019Seed$250K
#2
Series B · Chapel Hill, North Carolina · founded 1993 · 182 employees$177.8Mraised▾
Provider of personalized health improvement plans with financial incentives and concierge support. The company develops individualized health pathways based on member patterns and behaviors. It offers financial rewards for achieving health goals and provides live, on-demand concierge support for understanding healthcare bills, coverage, navigation, and provider scheduling. The company also delivers personalized health journeys and suggestions, along with coaching services to help members reach their objectives.
- Apr 2025Series B$30M
- Oct 2021Series B$71.9M
- Dec 2020Conventional Debt—
- Jun 2020Series A$50.9M
#3
Series A · Raleigh, North Carolina · founded 2020 · 12 employees$5.5Mraised▾
Medication management tool for healthcare professionals. The company has developed software that assists with patient health management and communication. The system has features for clinical outcomes management, clinical workflow management, prescription generation, and more.
- Feb 2026Series A$5.5M
#4
Series C · Raleigh, North Carolina · founded 2013 · 48 employees$51.3Mraised▾
Integrated technology solutions enhancing senior living community experiences and operational efficiency. The company provides a comprehensive suite of SaaS solutions designed for senior living communities. Their platform unifies applications, services, and devices to simplify communication, automate workflows, reduce administrative burdens, and streamline operations. They empower staff with data-driven insights to improve care, hospitality, and cost management. Their offerings include resident engagement applications, staff efficiency tools, voice-activated assistance, digital signage, smart home solutions, and an integration platform. The company focuses on improving the lives of residents, supporting staff, and enhancing overall community value through innovative technology and seamless integration. They offer multiple products and services.
- Mar 2025Series C$625K
- Jul 2023Series C$8.9M
- Feb 2022Series C$12M
- Nov 2021Conventional Debt$3.1M
#5
Series A · Wilmington, North Carolina · founded 2019$18Mraised▾
Provider of a clinical best practices implementation platform for healthcare teams. The platform unifies standards of care and consolidates clinical information into workflows. It offers tools for managing best practices, policy updates, and compliance. The platform integrates with existing systems and provides ongoing support for implementation and usage.
- Jul 2025Series A$12M
- Seed$6M
#6
Series C · Raleigh, North Carolina · founded 2007 · 46 employees$80Mraised▾
Studycast is a cloud PACS and echocardiogram reporting software solution for radiology, cardiology, and women's health. Studycast uploads all the ultrasound exams and other diagnostic testing results to the cloud. With Studycast, radiologists and providers can access medical images instantly, anywhere they have internet access. After alerting the radiologist that their images are ready and giving them immediate access, Studycast SmartWorksheets claims to make completing the interpretation efficient.
- Jan 2025Series C$80M
#7
Public · Charlotte, North Carolina · founded 2015 · 52 employees$3.5Mraised▾
Provider of cannabis products. It is an online store for users to purchase cannabis(CBD) products. The product categories include oil tincture, capsules, gummies, topicals, and animal products.
- Dec 2025Post IPO$2.2M
- Feb 2024Post IPO$1.2M
#8
Seed · Charlotte, North Carolina · founded 2022 · 6 employees$5.8Mraised▾
AI-based data-driven solutions for healthcare payors. The company is providing services such as population health and custom AI models to help healthcare payors optimize resources and improve health outcomes while reducing costs.
- Oct 2025Seed$3.5M
- Jan 2024Seed$5.8M
#9
Series A · Durham, North Carolina · founded 2021$23.5Mraised▾
Developer of boron-based medicines for various disease conditions. The company uses computational methods and a boron-based discovery platform to discover and develop drugs for undruggable targets.
- Feb 2025Grant (prize money)$464.5K
- Jan 2025Grant (prize money)$464.5K
- Jun 2023Conventional Debt$4M
- Sep 2022Series A$23.5M
#10
Series D · Morrisville, North Carolina · founded 2015 · 76 employees$44.8Mraised▾
Spencer Health Solutions is a provider of devices and apps for medication adherence. It gives vibration reminders and a medical/emergency alert system. The device syncs with its companion mobile application. Also allows users to scan and receive medication chronology and dosage information. Features include patient-reported outcomes collection, real-time insights, telehealth connections & others. The company also offers an app for tracking and managing medication dosage and adherence for patients and caregivers. It also provides solutions for patient engagement like it allows patients to answer health status questions by touch screen.
- Oct 2024Conventional Debt$5.1M
- Aug 2023Series D$43M
- May 2023Conventional Debt$6M
- Dec 2021Conventional Debt$15M
#11
Seed · Durham, North Carolina · founded 2023$4.3Mraised▾
Provider of AI-powered platform for clinical research participant recruitment workflows. The platform offers conversational engagement at scale, responding to participants quickly. It uses a library of conversations to maximize response rates. The platform adapts to different study requirements and indications. It facilitates pre-screening conversations via SMS and AI voice calls.
- Oct 2025Seed$4.3M
#12
Series A · Winston-salem, North Carolina · founded 2017 · 10 employees$3.7Mraised▾
OrbitalRX (previously known as Arxchitect) provides drug shortage management solutions. It provides tools to hospitals and pharmacies to address medication shortages and responding to supply chain threats. The platform allows the users to access drug information such as the drug stock in the inventory, automated storage inventory, and customizable labeling solutions. The inbuilt dashboard provides access to the information of the inventory and also assists with the communication system.
- Aug 2025Series A$1.2M
- Jan 2025Series A$958.9K
- May 2023Series A$1.4M
- Mar 2021Seed$150K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of HealthTech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health is moving in the United States
A read on the academic research around Digital Health — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 8,843 United States-affiliated papers.
- Design Intelligence421
- Harvard University383
- Johns Hopkins University295
- University of North Carolina at Chapel Hill206
- University of Washington173
- Health care9→240
- Wearable computer6→129
- Health informatics25→140
- Remote patient monitoring11→76
- Informatics10→60
- Health care36→766
- Health informatics113→495
- Psychological intervention20→320
- Public health34→290
- Intervention (counseling)5→193
- Health care98→1170
- Health informatics213→712
- Public health73→525
- Psychological intervention26→368
- Health administration110→363
Where digital health is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing medical devices patents in the United States
United States medical devices patent filing is accelerating — 666,693 filings from 8,000 assignees (2016–2025), led by Covidien, Boston Scient Scimed, Medtronic; annual filings 63466→63610.
- Covidien29351
- Boston Scient Scimed24775
- Medtronic22434
- Becton Dickinson18269
- Procter & Gamble16210
- Ethicon ENDO Surgery13758
- Kimberly Clark12462
- Ethicon11769
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.