Best Life Sciences Tech Companies in Maryland, United States
The 44 best Life Sciences Tech companies in Maryland, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Gene Logic.
Our analysis of 50 Life Sciences Tech companies
$9.6b in tracked funding; 89% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Life Sciences Tech companies in Maryland
| # | Company | Disclosed funding | Last round | Stage | Founder | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Gene Logic Integrated genomics company providing comprehensive Genomic Reference Databases and GLP compliant Microarray… | $29M | 349 mo ago | Public | — | 1994 | — | — | — |
| 2 | VeraChem Computational chemistry software for drug discovery and protein-ligand binding | $16M | 39 mo ago | Funding Raised | Michael Gilson Co-Founder & CEO | 2000 | — | — | — |
| 3 | SilcsBio Provides software and services for computer driven drug design | $7M | 17 mo ago | Funding Raised | — | 2012 | WordPressMySQLPHP+24 | — | — |
| 4 | HealthCare IT Software solutions for science and medicine | $5M | 222 mo ago | Deadpooled | Bill Tulskie CEO & CTO | 2008 | — | 425 patents Patents concentrated in computing, sensing & instrumentation | — |
| 5 | InforMax Scientific solutions provider: instruments, reagents, software, and services for researchers | $4M | 325 mo ago | Acquired | Alex Titomirov Founder | 1990 | — | — | — |
| 6 | CTIS Provider of health information technology and data management solutions | $3M | 122 mo ago | Funding Raised | Raj Shah Founder and Chairman Emeritus | 1988 | WordPressPleskMySQL+20 | — | 2 awards |
| 7 | RespondHealth Provider of an AI-based platform focused on clinical discovery to real-world health emergencies | $2M | 148 mo ago | Series A | Vicki Seyfert-Margolis Founder & CEO | 2013 | — | — | 1 launch |
| 8 | BioDatomics Next-generation bioinformatics tools for accelerated NGS data analysis and collaboration | $1M | 129 mo ago | Seed | Alan Taffel Co-Founder & CEO | 2012 | — | 11 patents Visualization and UI tools for big‑data scientific workflow creation and execution platforms | — |
| 9 | InfraTrac Light-based solutions for anti-counterfeiting, quality assurance, and controlled release | $604K | 47 mo ago | Funding Raised | — | 2006 | — | — | — |
| 10 | Fidelity Systems Developer of tools for advanced DNA and protein technologies | $539K | 207 mo ago | Funding Raised | Michael Fidelis CEO | 1997 | — | — | — |
| 11 | NexGen Forensic Sciences Developer of a DNA analysis tools for precision medicine development | $450K | 41 mo ago | Seed | Andrew B Feldman CEO | — | — | — | — |
| 12 | GalaxyWorks Provider of a SaaS-based omics data analysis platform for healthcare providers | $280K | 83 mo ago | Funding Raised | Dannon Baker Co-Founder | 2019 | — | — | — |
| 13 | Digidence Online platform for patient enegagement and data management | $150K | 92 mo ago | Seed | — | 2014 | — | — | — |
| 14 | JournalDoc Provider of search engine for medical expert | $125K | 187 mo ago | Seed | John M Nelson Founder & CEO | 2002 | — | — | — |
Top 12 Life Sciences Tech companies in Maryland
#1
Funding Raised · Baltimore, Maryland · founded 2012 · 7 employees$7Mraised▾
SilcsBio provides software and services for computer driven drug design. Its products include CGENFF to perform simulations on a system that contains a small organic molecule; SILCS, fragment-based drug design platform.
- Mar 2025Grant (prize money)$1.8M
- Nov 2021Grant (prize money)$1.8M
- Mar 2019Grant (prize money)$2M
- Mar 2015Grant (prize money)$1.5M
#2
Funding Raised · Germantown, Maryland · founded 2000 · 4 employees$15.6Mraised▾
Computational chemistry software for drug discovery and protein-ligand binding. The company provides state-of-the-art software solutions for protein-ligand binding affinity prediction, accurate partial atomic charge calculation, and conformational search. Their products include tools for 2D to 3D small molecule conversion, protein-ligand docking, chemical drawing, and molecular superposition. They offer solutions for analyzing molecular conformers, calculating RMSDs, and visualizing small molecules. The company's software supports drug discovery, offering capabilities like free energy calculations and integration with other software. They provide commercial licensing, customer support, and documentation for their software products.
- May 2023Grant (prize money)$2.1M
- Jun 2020Grant (prize money)$1.9M
- Apr 2018Grant (prize money)$1.6M
- Sep 2014Grant (prize money)$2.4M
#3
Public · Gaithersburg, Maryland · founded 1994 · 85 employees$29Mraised▾
Gene Logic was an integrated genomics company providing comprehensive Genomic Reference Databases and GLP compliant Microarray Services. It also offered drug development solutions to the pharmaceutical industry. It was also involved in clinical stage small molecule drug candidate, GL1001 whcih was repositioned as a drug candidate to treat gastrointestinal disease. In 2007, its genomic business was acquired by Ocimum Biosolutions.
- Jul 1997Series B$20M
- May 1996Series A$9M
#4
Seed · Columbia, Maryland$450.3Kraised▾
Developer of a DNA analysis tools for precision medicine development
#5
Funding Raised · Silver Spring, Maryland · founded 2006 · 2 employees$604.2Kraised▾
Light-based solutions for anti-counterfeiting, quality assurance, and controlled release. The company provides innovative solutions using light-activated chemical signatures to protect products from counterfeiting. They offer quality assurance for 3D printed products through NIR spectroscopy, verifying material integrity against reference models. Their controlled release technology utilizes 3D printed nano-containers, releasing payloads in response to environmental conditions. This technology has applications across pharmaceuticals, aerospace, and other industries. They focus on spectroscopic tagging and authentication, particularly for additive manufacturing, offering a promising technique for quality control and authentication. Their innovations extend to improving controlled release of liquids and powders across various industrial, manufacturing, and medical applications.
- Sep 2022Grant (prize money)$604.2K
- Jul 2007Grant (prize money)—
#6
Deadpooled · Rockville, Maryland · founded 2008$5Mraised▾
Software solutions for science and medicine. BIGR-Biospecimen Repository Management System is a biospecimen management solution to enter, track and manage all aspects of sample management for biobanks and biospecimen repositories. It also serves the cancer research community as a caBIG Service Support Provider and offers hosting capabilities for caBIG applications under a Software-As-A-Service model.
- Feb 2008Series A$3.6M
#7
Funding Raised · Rockville, Maryland · founded 1988 · 69 employees$3.1Mraised▾
Provider of health information technology and data management solutions. The company designs and implements solutions to improve patient outcomes and operational efficiency. It specializes in streamlining clinical trial processes, focusing on data management and health equity. The company offers services including IT modernization, AI enablement, and cloud computing.
- 2016Grant (prize money)$3M
- Aug 2014Grant (prize money)$145K
#8
Acquired · Bethesda, Maryland · founded 1990 · 223 employees$4Mraised▾
Scientific solutions provider: instruments, reagents, software, and services for researchers. The company offers a wide array of products including antibodies, chemicals, lab equipment, and consumables. It serves diverse applications across life sciences, pharma, food safety, and industrial sectors. Services encompass lab instrument support, custom solutions, training, and enterprise-level informatics. Digital solutions, e-procurement, and a comprehensive online presence facilitate ordering and support. The company empowers genetic discovery, accelerates science, and provides integrated workflows. It offers a broad portfolio of scientific tools and resources, including software, to support research and development. The business model includes product sales, service contracts, and digital solutions, catering to both B2B and research communities.
- Jul 1999Series A$4M
#9
Seed · Bethesda, Maryland · founded 2012 · 11 employees$1.1Mraised▾
Next-generation bioinformatics tools for accelerated NGS data analysis and collaboration. They provide powerful, intuitive bioinformatics tools designed to help genomic and biomedical researchers gain insights from their data more quickly. The company offers an open-source platform that accelerates research through a simple interface, visualized results, faster analysis, and real-time, web-based collaboration. Products include BioDT SaaS, a pay-as-you-go option via the public cloud; BioDT Pro, a full-featured version with enhanced security for private clouds; and BioDT Community, a free, downloadable open-source platform. They also offer custom workflow development services. Key features include visualized results, a drag-and-drop interface, accelerated analysis, an open platform supporting many bioinformatics tools, real-time collaboration, and compatibility with public and private cloud infrastructures. This is a B2B tech company offering SaaS and software solutions for bioinformatics analysis.
- Nov 2015Conventional Debt$185K
- Oct 2014Conventional Debt$200K
- May 2014Grant (prize money)$195.6K
- Apr 2014Seed$700K
#10
Series A · Bethesda, Maryland · founded 2013$1.9Mraised▾
Provider of an AI-based platform focused on clinical discovery to real-world health emergencies. It provide safe registries, advanced analytics and workflows for research, clinical trials, and medical device testing that aim is to detect and respond to health emergencies.
- Apr 2014Series A$1.9M
#11
Funding Raised · Gaithersburg, Maryland · founded 1997$538.6Kraised▾
Developer of tools for advanced DNA and protein technologies. It offer tools such as TopoTaq DNA Polymerase, known for its robustness in PCR amplification, and other products designed to enhance DNA sequencing and related molecular biology applications.
- May 2009Grant (prize money)$269.3K
- Apr 2009Grant (prize money)$269.3K
#12
Funding Raised · Baltimore, Maryland · founded 2019 · 2 employees$280Kraised▾
Provider of a SaaS-based omics data analysis platform for healthcare providers. The company has developed a digital platform that allows researchers and scientists with the data analysis process along with troubleshooting technology. The platform has tools for optimizing workflow, share work, collaborate with members, and collaborate on analyses. The software has tools for validation, practice management, and R&D production as well.
- Sep 2019Grant (prize money)$280K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Life Sciences Tech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Biotechnology in Maryland is moving
A read on the academic research around Biotechnology in Maryland — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 57 papers.
- University of Maryland, Baltimore25
- University of Maryland, College Park22
- University of Maryland, Baltimore County6
- University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center2
- Maryland Department of Health2
- Cell culture3
- Epithelium2
- Limiting2
- Bacillus thuringiensis2
- Arabidopsis2
- Prostate cancer2
- Recombinase Polymerase Amplification1
- Multiple displacement amplification1
- Loop-mediated isothermal amplification1
- Nucleic acid1
- Antibiotic resistance2
- Antimicrobial2
- Aquaculture1
- Population1
- Antibiotics1