Best Nanotechnology Companies in Spain
The 59 best Nanotechnology companies in Spain in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Splice Bio.
Spain's Nanotechnology sector is smaller than the headlines suggest, but it's moving fast enough to pay attention to. This directory ranks 59 tracked companies by disclosed equity funding and recent momentum, with $116M on the books total and Splice Bio commanding a striking $57M of that pool on its own.
That concentration tells you something. Strip out Splice Bio and the rest of the field is scrappy, early-stage, and hunting for the same EU capital from backers like EIC Fund, Caixa Capital Risc, and BeAble Capital. Bionicia sits at $3M, Graphenea at $1M, and several others like Nucaps Nanotechnology and Calpech are still in the hundreds of thousands. The global market context makes that gap feel urgent: forecasts put nanotechnology on a path toward $33.6B by 2030, driven by miniaturized devices and healthcare diagnostics. And the clinical signals are aligning with that bet, from nanotech approaches to glioblastoma to new Alzheimer's treatment research putting nanomedicine squarely at the center of the conversation. I'd watch nanomedicine and nanocapsule companies here closely this year.
- Nanotechnology Market to Expand at a CAGR of 10.36% by 2027
- Nanotechnology Market Forecast Unprecedented CAGR of 14.5% During 2022
Our analysis of 50 Nanotechnology companies
$6.5b in tracked funding; 78% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Nanotechnology companies in Spain
| # | Company | Disclosed funding | Last round | Stage | Founder | Employees | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Splice Bio Provider of a proprietary platform for gene therapy 37Funding top 29%Growth top 45%Moat top 48%Tech bottom 49% All 7 signals ▾Fundingtop 29% Growthtop 45% Moattop 48% Techbottom 49% Talentbottom 49% Globalbottom 38% Marketbottom 33% Funding: Raised $56.7M across 2 rounds · 2 rounds over 6 yrs (0.3/yr) Growth: Web rank 10,000,000 → 50,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 37/100 | $57M | 13 mo ago | Series B | Miquel Vila-Perello CEO | 24 | WordPressMySQLPHP+22 | — | — |
| 2 | Advancell Specialty company developing nanotech drug delivery for new applications of already-known molecules | $11M | 223 mo ago | Deadpooled | — | 17 | — | — | — |
| 3 | nLife Therapeutics Oligonucleotide-based therapies for Parkinsons's disease and other CNS disorders | $9M | 144 mo ago | Deadpooled | — | 17 | — | 46 patents Targeted delivery of oligonucleotides/mRNA to specific neurons and hepatic cells | — |
| 4 | AlphaSIP Nanotube-based biosensor chip for diagnostic applications | $8M | 95 mo ago | Funding Raised | Brent Segal Co-Founder | — | — | — | — |
| 5 | Nano Coatings Developer of a technology for nanocoating with synthetic diamonds | $4M | 82 mo ago | Funding Raised | Pedro Martin Velasco CEO | — | — | 5 patents Patents concentrated in electrical & electronics | — |
| 6 | Nanoimmunotech Characterization and functionalization of nanoparticles | $4M | 94 mo ago | Deadpooled | Christian Sanchez Espinel CEO | 11 | — | 6 patents Patents concentrated in transport & manufacturing processes | — |
| 7 | Gnanomat Developer of advanced materials for energy storage and printed electronics | $3M | 66 mo ago | Acquired | — | 9 | — | 11 patents Nanostructured carbon‑metal‑oxide catalysts for high‑performance metal‑air batteries | — |
| 8 | Nanogap Manufactures silver-based nanomaterials | $3M | 90 mo ago | Series A | — | 20 | WordPressMySQLPHP+22 | — | — |
| 9 | Bionicia Development of equipment to fabricate nanomaterials | $3M | 42 mo ago | Funding Raised | Hipolito Montejano Lozoya Co-Founder & CFO | — | WordPress Block EditorDiviWordPress+19 | — | — |
| 10 | Cebiotex Developer of nano-fiber-based drug delivery technology | $2M | 107 mo ago | Series A | Jose Antonio Tornero Co-founder and CTO | 7 | — | 9 patents Beaded nonwoven membrane technology for controlled drug delivery applications. | 1 award |
| 11 | Innoup Farma Nanotechnology solutions for drug delivery | $2M | 128 mo ago | Series A | Juan Irache Co-Founder | 8 | — | 33 patents Pharmaceutical mixing equipment and nanoparticle drug‑delivery formulation technologies. | — |
| 12 | Sagetis Biotech Drug delivery technologies | $2M | 179 mo ago | Series A | Eduard Diviu Terradas Co-Founder & CEO | 2 | — | 27 patents Poly(beta‑amino ester) polymer carriers for viral‑based gene and therapeutic delivery | — |
| 13 | Nadetech Developer of micro and nano materials processing based equipments | $1M | 60 mo ago | Seed | Francisco J Arregui Co-Founder | 17 | — | — | — |
| 14 | ADParticles Provider of a surface modification tool for dry dispersion of nanoparticles | $1M | 55 mo ago | Seed | — | 18 | — | — | — |
| 15 | Graphenea Developer of high-quality graphene devices and foundry services | $1M | 42 mo ago | Seed | Jesus Fuente Founder & CEO | 33 | Cart FunctionalityShopifyZoho+20 | 50 patents Graphene‑oxide reinforced adhesives and composites for laminated wood‑based panels | — |
| 16 | Avanzare Develops additive materials using nanotechnology | $938K | 110 mo ago | Late Stage | Julio Gomez Cordon President & CEO | — | — | — | — |
| 17 | Bionanoplus Developer of polymeric nanoparticles and microparticles as controlled release drug delivery systems | $899K | 76 mo ago | Seed | Hesham Salman Founder & CEO | 11 | — | 34 patents Topical cyclosporine formulations and polymeric nanoparticle drug‑delivery systems for dermatology | — |
| 18 | Calpech Carbon nanoparticle manufacturer 6Talent bottom 49%Funding bottom 38%Global bottom 29%Market bottom 16% All 4 signals ▾Talentbottom 49% Fundingbottom 38% Globalbottom 29% Marketbottom 16% Talent: 1 named leader on record · 1 C-suite/founder profile curated Funding: Raised $628k across 1 rounds · 1 rounds over 2 yrs (0.5/yr) rank vs industry peers · Fliar Intelligence Index 6/100 | $628K | 18 mo ago | Seed | Yuriy Budyk Co-Founder & CEO | 2 | — | — | 1 award |
| 19 | Mateprincs Manufacturer of conductive inks for printed electronic devices | $581K | 94 mo ago | Seed | Jose Echeverria Managing Director | 2 | — | — | — |
| 20 | Applied Nanoparticles Provider of the nanocomposites system | $529K | 75 mo ago | Funding Raised | Victor Puntes Founder | — | — | — | — |
| 21 | Nucaps Nanotechnology Provider of encapsulation technology for developing nanocapsules and biocapsules 9Moat top 45%Talent bottom 49%Funding bottom 47%Patents bottom 44% All 8 signals ▾Moattop 45% Talentbottom 49% Fundingbottom 47% Patentsbottom 44% Globalbottom 40% Techbottom 37% Marketbottom 23% Innovationbottom 23% Moat: Editorial + unicorn rating 5/10 · IP moat: 2 patents Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 9/100 | $440K | 22 mo ago | Seed | Mariano Oto CEO | 12 | WordPressMySQLPHP+14 | 2 patents Nanoparticle-based encapsulation systems for targeted phytomedicine cancer therapies | 2 awards |
| 22 | BIHURCRYSTAL Provider of novel materials and UHV equipments | $363K | 94 mo ago | Deadpooled | Francisco Lopez Gejo CEO | — | — | — | — |
| 23 | Distinkt Nano-ink manufacturer | $363K | 26 mo ago | Seed | Alex Lopez Co-Founder | — | WixSentryEnvoy+12 | — | 1 award |
| 24 | ControlNano Provides tool for exposure to nanoparticles | $219K | 75 mo ago | Funding Raised | Demetrio Gil CEO | — | — | — | — |
| 25 | Nanovex Biotech Nanoparticles for life science applications | $135K | 81 mo ago | Funding Raised | Rebeca Alonso Co-Founder & CSO | — | WordPressMySQLPHP+12 | — | — |
| 26 | Future Chromes Developer of nanotechnology-based photochromic materials | $111K | 73 mo ago | Funding Raised | Claudio Roscini Co-Founder & CEO | — | — | — | — |
| 27 | Yflow SD Mnufacturer of electrospinning equipment | $109K | 121 mo ago | Funding Raised | Rogelio Zubizarreta CEO | — | — | — | — |
Top 12 Nanotechnology companies in Spain
#1
Series B · Barcelona, Catalonia · founded 2020 · 24 employees$56.7Mraised▾
Provider of a proprietary platform for gene therapy. The company offers proprietary intein platform technology for treating patients suffering from rare genetic diseases. The company's lead program is in Stargardt disease, the most common inherited retinal disorder caused by mutations in a single gene ABCA4.
- Jun 2025Series B$135M
- Feb 2022Series A$56.7M
- Sep 2020Seed—
#2
Seed · Alacanti, Valencian Community · founded 2021 · 2 employees$628Kraised▾
Carbon nanoparticle manufacturer. It develops iron nanoparticles encapsulated in CE-nZVI for environmental solutions such as improvement of biogas production and elimination of hydrogen sulfide in biodigesters,elimination of heavy metals in contaminated water and soil, denitrification of aquifers , desulfurization of gaseous streams.
- Dec 2024Seed$628K
#3
Seed · Noain, Navarre · founded 2016 · 12 employees$440Kraised▾
NUCAPS provides encapsulation technology for developing nanocapsules and biocapsules. Its product includes a protein-based dry powder that can be filled in a capsule/sachet/pill. It is claimed to increase the solubility of the active compound and form stable suspensions in liquids. Additionally, it provides encapsulation services for bioactive and probiotics capsules. Its offerings have applications in the nutrition, food, pharmaceutical, cosmetics, and healthcare industries. The company also provides IP licenses for applications of its technology in multiple markets and owns 4 international patents for its protein-based nano/biocapsules. The company was found by a collaboration between CNTA, IDIFARMA, and the University of Navarra.
- Sep 2024Grant (prize money)$55.1K
- Nov 2023Conventional Debt$519.6K
- 2020Seed$440K
#4
Funding Raised · Paterna, Valencian Community · founded 2009$2.6Mraised▾
Bionicia is a technological spin-off of the Spanish Council for Scientific Research in 2012. It offers development and manufacturing of equipment to fabricate nanomaterials. Core technology includes electro-hydrodynamic processing, electrospinning, electrospraying, core-shell e-stretching, and others. It has a proprietary multifunctional mono- and multi-axial electrospinning and electrospraying processes as part of its Fluidnatek product line. Offers contract manufacturing for developing specialty materials, improving the performance of existing materials, scaling up and manufacturing of monophase, core-shell and multiphase fibers and particles.
- Jan 2023Grant (prize money)$327.9K
- Jul 2022Grant (prize money)$51.1K
- Aug 2019Grant (prize money)$763.9K
- Apr 2018Grant (prize money)$44.3K
#5
Seed · Barcelona, Catalonia · founded 2022$362.8Kraised▾
Nano-ink manufacturer. It uses nanotechnology to manufacter smart ink that helps prevent counterfeiting. It caters to currency, documents, luxury goods, and tax stamps.
- Apr 2024Seed—
- Feb 2024Grant (prize money)$362.8K
#6
Seed · San Sebastian, Basque Country · founded 2010 · 33 employees$1.1Mraised▾
Developer of high-quality graphene devices and foundry services. It is involved in manufacturing graphene materials, offering customized graphene foundry services on wafers up to 6 inches with tailored designs. The company produces high-quality graphene products, including films, sheets, and powders, for various applications such as bioengineering, energy technology, and composite materials. Its products are used in research and industrial settings, enabling fast development and testing of graphene-based solutions.
- Jan 2023Grant (prize money)$155.7K
- May 2021Grant (prize money)$1.1M
- Nov 2020Grant (prize money)$414.1K
- Oct 2020Grant (prize money)$613.6K
#7
Funding Raised · Zaragoza, Aragon · founded 2008$7.8Mraised▾
AlphaSIP designs, develops, and produces molecular diagnostic chips that allow immediate and effective illness detection, promoting better health services for patients and great advances towards personalized medicine. Its ASIP chip uses FET- based sensors (Field Effect Transistor) that detect changes in the conductivity on the surface of the chip, resulting in real-time medical diagnosis. Its ultrasensitive biosensor chip is based on nanotubes. The company is currently focused on 3 diagnostic kits, DrugSIP (a rapid drug test), PneumoSIP( a rapid test for pneumococci) & TromboChip (a quick test for deep venous thrombosis).
- Jul 2018Grant (prize money)$4M
- Nov 2015Grant (prize money)$3.7M
- Feb 2015Grant (prize money)$56K
- Oct 2014Grant (prize money)$63.1K
#8
Acquired · Madrid, Community of Madrid · founded 2014 · 9 employees$3.3Mraised▾
Developer of advanced materials for energy storage and printed electronics. The company focuses on manufacturing and commercializing materials for various industrial sectors. It leverages its carbon-hybrid materials platform to address industrial challenges. The company extends application potential with new technologies and products. It offers collaboration opportunities to co-develop solutions.
- Jan 2021Grant (prize money)$437.8K
- Nov 2018Grant (prize money)$1.4M
- Dec 2016Grant (prize money)$1.3M
- Jul 2016Grant (prize money)—
#9
Deadpooled · Armilla, Andalusia · founded 2010 · 17 employees$9.3Mraised▾
nLife Therapeutics is focussed on the development of cell-specific oligonucleotides as therapeutic agents for CNS disorders. It is developing a delivery platform, a two-component design which has a small drug that targets the selected group of cells and siRNAs / antisense oligonucleotides that reduce the amount of disease-related protein. Its lead candidate NLF-PD 1233 targets alpha-synuclein and reduce its accumulation which causes Parkinson's disease. It is also developing NLF-HD for Huntington disease, which reduces the level of altered Htt in striatal and cortical neurons thus stopping the disease progression.
- Jun 2014Series A$2.7M
- Feb 2012Series A$6.6M
#10
Deadpooled · Barcelona, Catalonia · founded 2001 · 17 employees$11Mraised▾
Advancell is a biotech nanomedicine company, engages in the development of drugs through the search for new applications for already-known molecules, and services and reagents. It also develops and markets in vitro cell models with a regulatory and/or predictive value. It focusses on oncology, dermatology, and CNS where their technologies and development capabilities can add distinctive value. Their technology utilizes polysaccharides and other excipients to generate nanosystems that confer new properties the active ingredient, thereby creating nanomedicine. The company was acquired by Indukern in 2008
- Dec 2007Series B$11M
#11
Deadpooled · Zaragoza, Aragon · founded 2009 · 11 employees$3.6Mraised▾
Nanoimmunotech provides technology for biological & physicochemical characterization and functionalization of nanoparticles. It provides bioconjugation of different nanomaterials, biomolecules such as nucleid acids, enzymes, antibodies, carbohydrates, peptides, etc, as well as other elements like nano-biosensors. These find applications in sectors like biomedical, pharmaceutics, cosmetics, veterinary, agro-food, environmental, etc.
- Sep 2018Grant (prize money)$238.8K
- Jan 2017Grant (prize money)$533.5K
- Sep 2016Grant (prize money)$1.5M
- Sep 2015Grant (prize money)$336.4K
#12
Series A · Santiago de Compostela, Galicia · founded 2006 · 20 employees$2.8Mraised▾
Nanogap is a spinout from University of Santiago de Compostela which manufactures silver based nanomaterials using a technology that is based on controlled wet chemistry. Using this technology platform they can produce Atomic Quantum Clusters, nanoparticles, and nanofibers. Their products are used in conductive inks, luminescent materials, antimicrobial coatings and therapeutic applications.
- Jan 2019Grant (prize money)$438.1K
- Jan 2017Grant (prize money)$236.5K
- Aug 2016Grant (prize money)$55.8K
- Mar 2016Grant (prize money)$54.4K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Nanotechnology coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Nanomaterials is moving in Spain
A read on the academic research around Nanomaterials — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,308 Spain-affiliated papers.
- Ikerbasque74
- Institució Catalana de Recerca i Estudis Avançats72
- Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine65
- Institute of Catalysis and Petrochemistry59
- Universidad Autónoma de Madrid53
- Nanoparticle13→146
- Catalysis2→59
- Nanocomposite3→38
- Quantum dot5→35
- Nanostructure2→31
- Nanoparticle14→146
- Catalysis5→51
- Nanocomposite4→45
- Quantum dot1→23
- Colloidal gold3→23
- Catalysis2→6
- Nanoparticle8→9
Where nanomaterials is researched across Spain
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.