Artificial Intelligence · Illinois, India

Best Artificial Intelligence Companies in Illinois, United States

Updated 2026-06-22 · Ranked by funding & momentum

93 indexable Artificial Intelligence companies headquartered in Illinois, United States, ranked by total equity funding and recent funding momentum. Combined disclosed equity funding of $2B across 33 funded companies, including 3 unicorns.

93
Companies
$2B
Total Funding
33
Funded
3
Unicorns
2
Rounds (90d)

Ranked: Best Artificial Intelligence companies in Illinois

#CompanyFundingValuationStage Latest roundEmployeesFoundedMomentum
1 Loop
Provider of a logistics data platform offering freight audit and visibility
$65M Series C Series C Apr 2026 47 2021 ↑ Active
2 K1x
Provider of AI-powered automation software for K-1, K-3, and 990 tax reporting
$35M Series B PE Apr 2026 61 2022 ↑ Active
3 Thoughtful
AI-powered healthcare administration platform to automate tasks
$20M Series A PE Apr 2025 16 2020 ↑ Active
4 Mattiq
Developer of an experimentation platform for accelerating materials discovery and design
$24.1M Seed Seed Dec 2024 19 2020 ↑ Active
5 Vermill
Provider of AI rights management platform protecting and licensing digital content
$16M Series A Series A Mar 2025 21 2021 ↑ Active
6 Tempus Unicorn
Developer of genomic testing and artificial intelligence tools for medicine
$1.1B $8.1B
as of 2020
Public Conventional Debt Oct 2022 772 2015
7 ModelOp
Platform offering machine learning model deployment and management
$16M Series B Series B Aug 2024 36 2016 ↑ Active
8 Arvist
Provider of AI-powered solutions for warehouse quality control and compliance
$1.1M Series A Series A Jul 2025 7 2021 ↑ Active
9 FourKites Unicorn
Developer of AI and web-based visibility solutions for the supply chain
$243.3M Series D Series D Sep 2022 24 2014
10 Identomat
Provider of AI-powered identity verification and KYC/AML compliance platform
$3.2M Seed Seed Jan 2025 32 2019 ↑ Active
11 Gideon
Developer of autonomous mobile robots for material handling in various industries
$38.5M Series A Series A Apr 2024 127 2015
12 iAsk AI
Developer of an AI search engine providing detailed, accurate responses
$4.2M Seed Seed Oct 2024 2022 ↑ Active
13 Pando
Provider of AI-powered solutions for freight management and supply chain
$45M $73.4M
as of 2021
Series B Series B May 2023 250 2018
14 Altris
AI-based diagnostic solution for ophthalmologists
$1M Seed Seed Jan 2025 15 2018 ↑ Active
15 Uptake Unicorn
Cloud-based platform for predictive analytics and asset performance management
$282.3M $2.3B
as of 2017
Series D Series D 2018 102 2014
16 ProvenAir
Provider of AI-powered platform for aircraft records management and compliance
$1.8M Series A Series A Jul 2024 13 2015 ↑ Active
17 eSpark Learning
Personalized learning on the iPad for schools
$30.7M Series C Series C Jan 2022 41 2010
18 Narrative Science
Provider of an AI-based content creation solution
$47.5M Acquired Series D Apr 2017 64 2010
19 Market Logic
Provider of AI-powered market and competitive intelligence platform for businesses
$50.3M Series C Series C May 2017 321 2005
20 Ascent
Cloud-based platform to track and automate financial regulatory compliance
$26.7M Acquired Series B Nov 2019 47 2015
21 Tagado
Provider of SaaS-based ML and NLP technology for data collection and analytics platform for marketing
$4M Seed Seed Nov 2022 10 2021
22 Neurensic
Regulatory compliance using Artificial Intelligence
$9M Acqui-Hired Seed Mar 2017 186 2015
23 Samya.ai
AI-based SaaS platform for consumer packaged goods companies
$6M Acqui-Hired Seed Jan 2020 61 2019
24 Clockwork
AI & cloud-based cash flow management solutions for small businesses
$2M Seed Seed Apr 2022 11 2018
25 Rippleshot
Provider of AI-driven banking fraud analytics and detection platform solutions
$4.8M Series A Series A Aug 2018 10 2013
26 QuillBot
Provider of an AI-based paraphrasing tool
$4.3M Acquired Seed Apr 2020 171 2017
27 Semantify
Knowledge based Data Discovery and Analytics Platform
$3.2M Series A Series A May 2016 25 2008
28 Blinkfire Analytics
Sports media analytics
$2.6M Seed Seed Jun 2017 27 2013
29 Telnyx
Provider of voice AI platform with global telecommunications infrastructure
$2.2M Seed Seed Nov 2014 106 2009
30 Rhetora
Cloud and AI based cold calling sales enablement solutions for sales teams
$120K Deadpooled Seed Sep 2023 6 2022
31 Brain.fm
Developer of music designed to enhance focus and cognitive performance
$225K Funding Raised Grant (prize money) Mar 2018 13 2014
32 Parkster
AI-enabled platform offering parking space detection and management solutions
$20K Seed Seed Sep 2022 2021
33 Edge Up Sports
Provider of a data analytics platform for sports
$30K Deadpooled Grant (prize money) Jun 2015 6 2014
34 Chaos
Offering secure communication solutions
Deadpooled Seed Apr 2021 5 2021
35 Wolfram
Developer of software for technical computing, data science, and AI
Funding Raised Grant (prize money) Dec 2019 414 1987
36 3pm Ai
Cloud based platform offering safety management compliance solutions
Acquired 33 2013
37 ae machines, inc
AE Machines is a manufacturer of program and reprogram simple automated systems.
Private 5 2015
38 Agentic Private Markets
Developer of AI agents for private market investment and analysis
Unfunded 2025
39 AIDO
Provider of an AI platform for international student enrollment management
Unfunded 2024
40 Aktiver
Developer of a platform automating ontology and taxonomy development using AI
Unfunded 2020
41 analyticsplus
AnalyticsPlus is an analytics and predictive modeling company with strong domain knowledge in healthcare and other industries.
Private 10 2010
42 anthro innovations
Anthro Innovations is an information technology & services company.
Private 4 2016
43 askwhai
We choose to build the moon.
Private 2 2018
44 athreon
Athreon provides prompt and reliable insurance transcription for all facets of the insurance industry.
20 1988
45 AtyaSecure
Provider of AI-driven threat detection, risk management, and digital asset control
Unfunded 2024
46 bob.tv
Explorer of industries. Passionate sharer of content. Creator of communities. Go-to guy for all things relevant.
Acquired 8 2012
47 Botenders
Provider of AI-powered assistant for developers
Unfunded 2024
48 cardio diagnostics
Cardio Diagnostics makes heart disease prevention and early detection more accessible, personalized, and precise.
Public 8 2017
49 Chirpz
Developer of an AI agent for academic paper discovery and citation
Unfunded 2025
50 CogniSure
Cognitive AI platform for the insurance industry
Funding Raised 74 2019

Top 12 Artificial Intelligence companies in Illinois

#1
Loop Series C
$65M Raised
expand_more
location_onChicago, Illinois
Founded
2021
Employees
47
Funding raised
$65M
Stage
Series C

Provider of a logistics data platform offering freight audit and visibility. The platform unifies shipment and tracking data, enabling logistics teams to operate efficiently. It offers features such as parcel contract intelligence and carrier payments. The platform provides tools for cost allocation, decision intelligence, and transportation network optimization.

Funding rounds (4 disclosed of 4)
Round Date Amount
Series C Apr 2026 $95M
Series B Oct 2023 $35M
Series A Nov 2022 $24M
Seed 2021 $6M
Tech stack
amazon s3amazon sesamazon web servicesapple icloud mailchili pipercloudflare+14
#2
K1x Series B
$35M Raised
expand_more
location_onChicago, Illinois
Founded
2022
Employees
61
Funding raised
$35M
Stage
Series B

Provider of AI-powered automation software for K-1, K-3, and 990 tax reporting. This software automates the receipt and production of K-1s, streamlining the process for both investors and advisors. It also offers automated 990 exempt reporting and filing, including e-filing capabilities. The platform integrates with various other software solutions and provides support, training, and onboarding services. The software

Funding rounds (3 disclosed of 3)
Round Date Amount
PE Apr 2026 $175M
PE Sep 2024 $20M
Series B Dec 2022 $15M
Tech stack
aosautoptimizeazurecloudflarecloudflare bot managementcomplianz+14
#3
Thoughtful Series A
$20M Raised
expand_more
location_onChicago, Illinois
Founded
2020
Employees
16
Funding raised
$20M
Stage
Series A

AI-powered healthcare administration platform to automate tasks. The company offers solutions for automating revenue cycle management, streamlining company processes, and implementing robotic process automation (RPA).

Funding rounds (1 disclosed of 2)
Round Date Amount
PE Apr 2025 Undisclosed
Series A Jul 2024 $20M
Tech stack
webflowyoutubejquerygoogle tag managerpriority hintsjsdelivr+2
#4
Mattiq Seed
$24.1M Raised
expand_more
location_onSkokie, Illinois
Founded
2020
Employees
19
Funding raised
$24.1M
Stage
Seed

Developer of an experimentation platform for accelerating materials discovery and design. The platform transforms materials discovery from trial-and-error methods to intelligence-driven design. The company aims to unlock the materials blueprint, igniting the next era of human progress.

Funding rounds (8 disclosed of 8)
Round Date Amount
Seed Dec 2024 $4.5M
Grant (prize money) Sep 2024 $275K
Grant (prize money) Jul 2023 $1.3M
Grant (prize money) Feb 2023 $199.7K
Grant (prize money) Feb 2023 $255.9K
Seed Feb 2023 $15M
2 earlier rounds — sign up free
#5
Vermill Series A
$16M Raised
expand_more
location_onChicago, Illinois
Founded
2021
Employees
21
Funding raised
$16M
Stage
Series A

Provider of AI rights management platform protecting and licensing digital content. The platform offers tools to manage terms, conditions, and usage rights for content. It helps content owners protect against unauthorized use, deepfakes, and distribution. The platform also provides content monitoring and risk assessment services. It aims to enable content owners to capitalize on revenue streams from generative AI.

Funding rounds (1 disclosed of 1)
Round Date Amount
Series A Mar 2025 $16M
#6
Tempus Unicorn Public
$1.1B Raised
expand_more
location_onChicago, Illinois
Founded
2015
Employees
772
Funding raised
$1.1B
Valuation
$8.1B · 2020
Stage
Public

Developer of genomic testing and artificial intelligence tools for medicine. This organization provides molecular profiling, algorithmic diagnostic models, and digital pathology services to assist in clinical decision-making. The technology integrates clinical data with sequencing results to identify therapeutic options and potential clinical trial matches. These tools support oncology, neurology, psychiatry, cardiol

Funding rounds (6 disclosed of 8)
Round Date Amount
Series G Oct 2022 Undisclosed
Conventional Debt Oct 2022 Undisclosed
Series G Dec 2020 $200M
Series G Mar 2020 $100M
Series F May 2019 $200M
Series E Aug 2018 $110M
2 earlier rounds — sign up free
Tech stack
acquia cloud platformacquia cloud site factoryadobe analyticsadobe experience platform identity serviceadobe experience platform launchakamai+14
#7
ModelOp Series B
$16M Raised
expand_more
location_onChicago, Illinois
Founded
2016
Employees
36
Funding raised
$16M
Stage
Series B

Platform offering machine learning model deployment and management. It enables data scientists, IT professionals, and business teams to deploy, monitor and govern artificial intelligence models. Has use case in credit scoring, bond trading, model risk management and trading applications.

Funding rounds (2 disclosed of 3)
Round Date Amount
Series B Aug 2024 $10M
Series A 2023 Undisclosed
Series A Mar 2020 $6M
Tech stack
cloudflarecloudflare bot managementcookiebotcore-jsgoogle analyticsgoogle font api+14
#8
Arvist Series A
$1.1M Raised
expand_more
location_onChicago, Illinois
Founded
2021
Employees
7
Funding raised
$1.1M
Stage
Series A

Provider of AI-powered solutions for warehouse quality control and compliance. It automates inspections, detects hazards, enforces safety rules, and monitors restricted areas. The platform integrates with existing systems and equipment, providing real-time alerts and dashboards. It helps to standardize quality checks, reduce errors, and improve overall warehouse efficiency.

Funding rounds (3 disclosed of 3)
Round Date Amount
Series A Jul 2025 $5.9M
Seed Nov 2023 $1.1M
Seed 2022 $20K
#9
FourKites Unicorn Series D
$243.3M Raised
expand_more
location_onChicago, Illinois
Founded
2014
Employees
24
Funding raised
$243.3M
Stage
Series D

Developer of AI and web-based visibility solutions for the supply chain. It provides users with real-time visibility solutions for shippers, brokers, 3PLs, and carriers. It uses machine learning and AI to provide predictive insights and real-time supply chain information. It also enables users to calculate shipment arrival times and uses GPS or ELD devices for covering all modes including ocean, rail, parcel, and ove

Funding rounds (8 disclosed of 9)
Round Date Amount
Series D Sep 2022 $10M
Series D Aug 2022 $30M
Series D Jun 2022 Undisclosed
Series D Mar 2021 $100M
Series C Feb 2019 $50M
Series B Feb 2018 $35M
3 earlier rounds — sign up free
Tech stack
akamaiakamai mpulseamazon cloudfrontamazon web servicesapple icloud mailboomerang+14
#10
Identomat Seed
$3.2M Raised
expand_more
location_onChampaign, Illinois
Founded
2019
Employees
32
Funding raised
$3.2M
Stage
Seed

Provider of AI-powered identity verification and KYC/AML compliance platform. The platform offers identity verification using government-issued identification, biometric data, and authoritative sources. It facilitates video-based verification, AML screening, business verification, and age verification. The platform includes modules for ID verification, liveness detection, face matching, and address verification, alon

Funding rounds (2 disclosed of 2)
Round Date Amount
Seed Jan 2025 $1M
Seed Jan 2022 $3.2M
Tech stack
cloudflarecloudflare bot managementcore-jsfacebook pixelgoogle analyticsgoogle font api+14
#11
Gideon Series A
$38.5M Raised
expand_more
location_onBolingbrook, Illinois
Founded
2015
Employees
127
Funding raised
$38.5M
Stage
Series A

Developer of autonomous mobile robots for material handling in various industries. The company's robots automate manual material-handling jobs in manufacturing, logistics, warehousing, and retail. The robots are designed to work safely with people and equipment. The company's technology aims to improve process stability and throughput.

Funding rounds (3 disclosed of 4)
Round Date Amount
Series A Apr 2024 $4.6M
Series A Jun 2021 $31M
Seed Oct 2019 $2.9M
Seed 2016 Undisclosed
Tech stack
backdropcloudflarecloudflare bot managementcloudflare browser insightscloudflare rocket loadercore-js+14
#12
iAsk AI Seed
$4.2M Raised
expand_more
location_onChicago, Illinois
Founded
2022
Funding raised
$4.2M
Stage
Seed

Developer of an AI search engine providing detailed, accurate responses. The engine enables users to ask questions in natural language and receive answers. It offers features such as document analysis, image creation, and grammar checking. The platform also provides tools for summarizing web content and brainstorming content ideas.

Funding rounds (1 disclosed of 1)
Round Date Amount
Seed Oct 2024 $4.2M
Tech stack
alpine.jsamazon sesamazon web serviceselixirerlanggoogle analytics+9

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Funding & investor landscape

Total raised
$2B
across these companies
Companies funded
33
with disclosed funding
Highest-funded
$1.1B raised

Most active investors

Plug and Play Tech Center Plug and Play Tech Center 6 investments in Artificial Intelligence Techstars Techstars 4 investments in Artificial Intelligence Service Provider Capital Service Provider Capital 3 investments in Artificial Intelligence Valor Equity Partners Valor Equity Partners 3 investments in Artificial Intelligence Baillie Gifford Baillie Gifford 2 investments in Artificial Intelligence Chicago Early Growth Ventures Chicago Early Growth Ventures 2 investments in Artificial Intelligence DNS Capital DNS Capital 2 investments in Artificial Intelligence KDWC Ventures KDWC Ventures 2 investments in Artificial Intelligence KGC Capital KGC Capital 2 investments in Artificial Intelligence Lightbank Lightbank 2 investments in Artificial Intelligence Method Capital Method Capital 2 investments in Artificial Intelligence New Enterprise Associates New Enterprise Associates 2 investments in Artificial Intelligence

Notable founders in Illinois Artificial Intelligence

MM Matt McKinney Co-Founder & CEO Loop · $65M raised
NS Neal Schneider Co-Founder K1x · $35M raised
JL John LaMancuso CEO K1x · $35M raised
Alex Zekoff Alex Zekoff Co-Founder & CEO Thoughtful · $20M raised
Dan Parsons Dan Parsons Co-Founder, CMO/CPO Thoughtful · $20M raised
Andrey Ivankin Andrey Ivankin Co-Founder & Chief Technology Officer Mattiq · $24.1M raised
Dan Neely Dan Neely Co-Founder & CEO Vermill · $16M raised
BL Brad Lehner Co-Founder Vermill · $16M raised
RM Ryan Mchale Co-Founder & CTO Vermill · $16M raised
EL Eric Lefkofsky Founder & CEO Tempus · $1.1B raised
Stu Bailey Stu Bailey Co-Founder ModelOp · $16M raised
Pete Foley Pete Foley CEO ModelOp · $16M raised

Frequently asked questions

How many Artificial Intelligence companies are there in Illinois, United States?
Radar tracks 93 indexable Artificial Intelligence companies headquartered in Illinois, United States that meet our profile-completeness bar.
What is the total funding raised by Artificial Intelligence companies in Illinois, United States?
The Artificial Intelligence companies in Illinois, United States on this list have raised a combined $2B in disclosed equity funding across 33 funded companies.
Which is the highest-funded Artificial Intelligence company in Illinois, United States?
Tempus is the highest-funded Artificial Intelligence company in Illinois, United States, with $1.1B in disclosed equity funding.
How many Artificial Intelligence companies in Illinois, United States are funded?
33 of the 93 Artificial Intelligence companies in Illinois, United States on this list have disclosed at least one equity funding round.
How many Artificial Intelligence unicorns are there in Illinois, United States?
3 Artificial Intelligence companies in Illinois, United States on this list are valued at $1B or more.
Who are the top investors in Illinois, United States Artificial Intelligence companies?
The most active investors in Illinois, United States Artificial Intelligence companies on this list include Plug and Play Tech Center, Techstars, Service Provider Capital, Valor Equity Partners, Baillie Gifford.

Rankings are computed by Radar (Fliar BI) from the Radar company master and are updated periodically. Funding and momentum scores use disclosed equity-funding data only. Figures may lag private rounds. Last updated 2026-06-22.

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