Best Disease Self Management Companies in Colorado, United States
The 68 best Disease Self Management companies in Colorado, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: BioIntelliSense.
Our analysis of 50 Disease Self Management companies
$3.0b in tracked funding; 94% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Disease Self Management companies in Colorado
| # | Company | Disclosed funding | Last round | Stage | Founder | Employees | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | BioIntelliSense Developer of medical-grade wearable devices and data services for patient monitoring 50Funding top 21%Moat top 21%Patents top 25%Innovation top 26% All 10 signals ▾Fundingtop 21% Moattop 21% Patentstop 25% Innovationtop 26% Producttop 35% Talenttop 38% Techbottom 49% Globalbottom 40% Marketbottom 36% Customersbottom 3% Funding: Raised $82.0M across 4 rounds · 4 rounds over 8 yrs (0.5/yr) Moat: Editorial + unicorn rating 8/10 · IP moat: 47 patents rank vs industry peers · Fliar Intelligence Index 50/100 | $82M | 6 mo ago | Series C | James Mault Co-Founder&CEO | 26 | WordPressApple iCloud MailMicrosoft 365+21 | 47 patents Patents concentrated in health & consumer products | — |
| 2 | Riva Health Mobile-based application for monitoring blood pressure | $32M | 45 mo ago | Series A | — | 32 | Webflow EcommerceWebflowApple iCloud Mail+16 | — | — |
| 3 | Prima-Temp Digital health technology empowering women through data and AI for better health | $15M | 86 mo ago | Series A | — | 2 | — | 20 patents Vaginal temperature sensing devices for reproductive health monitoring | — |
| 4 | Sana Developer of a wearable sleep inducer for individuals | $14M | 70 mo ago | Seed | Richard Hanbury Chief Executive Officer | 23 | Cart FunctionalitySquarespace CommerceSquarespace+17 | — | — |
| 5 | SOBR Safe Manufacturer of medical devices 48Product top 28%Tech top 34%Growth top 35%Talent top 38% All 12 signals ▾Producttop 28% Techtop 34% Growthtop 35% Talenttop 38% Innovationtop 40% Patentstop 41% Fundingtop 42% Newstop 43% Moatbottom 49% Fin. healthbottom 35% Globalbottom 32% Marketbottom 22% Product: 1 published app (718 installs) · Company stage: Public Tech: 54 technologies across 5/8 capability areas · Cloud: Cloudflare rank vs industry peers · Fliar Intelligence Index 48/100 | $13M | 5 mo ago | Public | Kevin Moore CEO | 15 15 → 15 (+0%) | Cart FunctionalityShopifyShop Pay+32 | 15 patents Patents concentrated in health & consumer products | — |
| 6 | AbleLink Smart Living Technologies Provider of solution for cognitive disabilities | $9M | 17 mo ago | Funding Raised | Daniel K. Davies Founder & President | 6 | — | — | — |
| 7 | Kindara Fertility tracking app and community empowering women to understand their bodies | $8M | 119 mo ago | Acquired | — | 9 | Cart FunctionalitySquarespace CommerceSquarespace+14 | 8 patents Wireless basal body temperature fertility monitoring devices and associated mobile integration | — |
| 8 | FRENZ Provider of wearable headband for inducing sleep and relaxation | $7M | 36 mo ago | Seed | Tam Vu Founder & CEO | 32 | Shogun Page BuilderWebflowShopify+41 | — | — |
| 9 | Neuromonics App for treating tinnitus | $3M | 176 mo ago | Series A | Paul B. Davis PhD Founder | 12 12 → 12 (+0%) | Framer SitesReactCloudflare+11 | — | — |
| 10 | Vivos Developer of a medical treatment plan for sleep apnea management | $3M | 31 mo ago | Public | — | 154 | WordPressMySQLPHP+21 | 15 patents Formulating radiotherapy gels and yttrium‑phosphate radioactive suspensions for cancer therapy | — |
| 11 | Serenity Engage Provider of software solutions for mental health monitoring of elderly people | $2M | 61 mo ago | Seed | — | 8 | — | — | — |
| 12 | LifeFilez Provider of a digital platform to store health documents | $1M | 71 mo ago | Deadpooled | Beth Krauklis CEO | — | — | — | — |
| 13 | Respirogen Developer of oxygen delivery technology | $750K | 84 mo ago | Seed | Bob Scribner CEO | 4 | GoDaddy Website BuilderReactLodash+6 | 11 patents Oxygen delivery systems for medical, cosmetic, and food applications, plus gas‑sensitive packaging. | — |
| 14 | Analyte Logic Sensor system for Postoperative Opioid-Induced Respiratory Depression prevention | $700K | 148 mo ago | Deadpooled | Nicholas L. Taro Founder | 5 | — | — | — |
| 15 | ZenVault Cloud-based personal health record | $678K | 132 mo ago | Deadpooled | Alan Gin Co-Founder | — | — | — | — |
| 16 | Instream water Smart water bottle and wristband for water refilling | $562K | 67 mo ago | Seed | Patrick Mahncke Founder & CEO | 2 | — | — | — |
| 17 | PillGuard Pill bottle for medical adherence. | $340K | 155 mo ago | Deadpooled | Anthony Mceldowney Interim CEO | — | — | — | — |
| 18 | Bravrr Provider of wearable device and an app diagnostics & digital therapeutics for clinicians and patients | $280K | 72 mo ago | Seed | — | 3 | — | 3 patents Dental muscle activity monitoring sensors for bruxism diagnosis and therapy | — |
| 19 | Connetix Health Provider of cloud-based app for personal health record | $225K | 94 mo ago | Seed | — | 7 | — | — | — |
| 20 | Best Shot Provider of mobile app for fertility management | $200K | 72 mo ago | Seed | — | 6 | — | — | — |
| 21 | Sleep Easy Provider of clinically-proven solution for sleep, stress and anxiety management for employees | $135K | 196 mo ago | Funding Raised | Kate Maloney CEO | 6 | — | 9 patents Neck-supported medical gas delivery devices for patient respiratory therapy | — |
| 22 | GeoPalz Activity trackers for children | $120K | 159 mo ago | Seed | Alexandra Zan O'Leary Co-Founder & COO | 3 | — | — | — |
Top 12 Disease Self Management companies in Colorado
#1
Series C · Denver, Colorado · founded 2018 · 26 employees$82Mraised▾
Developer of medical-grade wearable devices and data services for patient monitoring. it provides BioButton a rechargeable, multi-parameter wearable that captures vital signssuch as heart rate, respiratory rate, and skin temperature. It is integrated with data platforms BioCloud that provides advanced analytics and algorithmic notifications to support actionable triage and workflow efficiency and BioDashboard that Enables exception-based management for more proactive clinical decision-making.
- Dec 2025Series C$58.1M
- Jul 2021Series B$45M
- Aug 2020Series B$12M
- Dec 2018Series B$25M
#2
Public · Boulder, Colorado · founded 2007 · 15 employees$12.7Mraised▾
Manufacturer of medical devices
- Dec 2025Post IPO$2M
- Sep 2022Post IPO$6M
- Sep 2021Post IPO$3M
- Aug 2020Post IPO$1.7M
#3
Funding Raised · Colorado Springs, Colorado · founded 1997 · 6 employees$8.9Mraised▾
AbleLink Technologies provides a solution for people suffering from cognitive disabilities. The company flagship products AbleLink WayFinder is for GPS-based navigation support, Smart Living Mobile Suite/Desktop Suite have multiple apps for disables for keeping their track throughout the day, support for performing daily tasks and AbleLink ATLAS is cloud-based service for intellectual and developmental disabilities patients. It also offers several research-based services for developing technologies for support for intellectual disabilities, autism spectrum disorders, traumatic brain injuries, and age-related cognitive decline among others.
- Jan 2025Grant (prize money)$295.9K
- Sep 2024Grant (prize money)$295.9K
- Sep 2017Grant (prize money)$1.7M
- Oct 2014Grant (prize money)$75K
#4
Series A · Denver, Colorado · founded 2013 · 32 employees$32Mraised▾
Mobile-based application for monitoring blood pressure. The platform allows users to manage heart rate, hypertension, and overall cardiovascular healthcare.
- Sep 2022Series A$7.2M
- Mar 2021Series A$15.5M
- Dec 2020Series A$12.5M
- Nov 2016Series A$567.4K
#5
Seed · Boulder, Colorado · founded 2018 · 32 employees$6.8Mraised▾
Provider of wearable headband for inducing sleep and relaxation. FRENZ is a wearable device that uses artificial intelligence (AI) to monitor and records data such as brain signals (EEG), Eye motion (EOG), and Facial micro-muscle movements (EMG) to deliver personalized clinically-proven CBT-i sleep-inducing or focus-boosting audio content via the integrated bone-conduction speakers.
- Jun 2023Seed—
- Jan 2022Seed$6.8M
#6
Public · Highlands Ranch, Colorado · founded 2016 · 154 employees$3Mraised▾
Developer of a medical treatment plan for sleep apnea management. The company has developed a multidisciplinary treatment procedure that assists professionals and individuals to self-assess sleeping problems. It can be used by doctors to treat dentofacial abnormalities and by [atients to go through sleep assessment.
- Oct 2023Post IPO—
- May 2019Seed$556.5K
- Sep 2016Grant (prize money)$2.4M
#7
Seed · Lafayette, Colorado · founded 2015 · 23 employees$13.8Mraised▾
Developer of a wearable sleep inducer for individuals. It offers a smart sleeping mask to manage sleeping and neurological disorders. The wearable device measures sleep and health data over time that is transferred to a platform. The software uses the measured data to analyze and provide tailored programs on deep relaxation for sleeping and aid patients in improving neurological disorders.
- Jul 2020Seed$5.8M
- Dec 2019Grant (prize money)—
- Aug 2019Seed$240K
- Sep 2018Grant (prize money)$350K
#8
Series A · Boulder, Colorado · founded 2010 · 2 employees$15.3Mraised▾
Digital health technology empowering women through data and AI for better health. The company is focused on women's health, leveraging continuous data tracking and community to empower informed health decisions. Their digital health approach converges technologies, harvesting big data into a mobile platform, utilizing continuous data for predictive insights, and applying chronobiology. This enables the creation of clinical solutions using artificial intelligence. The company's technology captures core body temperature variances to provide precise information, acting as a circadian biomarker. Their solutions include fertility management and future applications in metabolic disorders and menopause. They offer a wearable solution designed to support continuous, remote monitoring, facilitating virtual patient-provider interactions and clinical diagnostic support. The company's platform integrates a large community and health data points to inform their clinical application roadmap.
- Apr 2019Series A$5M
- Oct 2017Series A$5.4M
- Feb 2016Series A$1.6M
- Dec 2015Seed$1.2M
#9
Seed · Golden, Colorado · founded 2016$98.4Kraised▾
SomnoHealth is a developer of a wearable sleep monitoring device. The company's product EverSleep sleep tracker is worn around the wrist and has a built-in pulse oximeter that provides blood oxygen saturation monitoring, in addition to an accelerometer for noticing motion, and a sound monitor for detecting any snoring. The device is paired with an app, which allows review of all the data and to receive personalized coaching to improve sleep based on results from prior nights. The device is claimed not only to monitor sleeping patterns but will detect conditions such as snoring, apnea, and insomnia. The company launched an Indiegogo crowdfunding campaign in May 2017, for its device.
- Oct 2024Seed$98.4K
#10
Acquired · Boulder, Colorado · founded 2009 · 9 employees$7.8Mraised▾
Fertility tracking app and community empowering women to understand their bodies. This digital fertility charting system helps individuals get pregnant faster and learn more about their reproductive health. It supports fertility awareness-based methods, providing a trusted platform for tracking and understanding cycles. The app is available for both iOS and Android, offering accessible tools for women seeking to manage their fertility naturally. This Software as a Service (SaaS) platform fosters a community, empowering users with knowledge and support for their fertility journeys. It is a B2C tech company.
- Jul 2016Seed$550K
- Aug 2015Seed$5.3M
- Nov 2014Seed$1.2M
- Nov 2013Seed$370K
#11
Seed · Denver, Colorado · founded 2011 · 8 employees$2.2Mraised▾
Provider of software solutions for mental health monitoring of elderly people
- May 2021Seed$1.2M
- Apr 2021Seed$945K
#12
Series A · Westminster, Colorado · founded 2002 · 12 employees$3.3Mraised▾
Neuromonics is a developer of treatment solutions for ringing in the ears. Their solution is a patented and FDA approved medical device designed for tinnitus relief. It also has a connected downloadable product for mobile devices called the Neuromonics Tinnitus Alleviator. The app makes the user listen to spectrally modified music designed to retrain the brain to ignore the ringing sounds and stop reacting negatively to them. The app includes a hearing test which allows users to customize the four soundtracks. The app can be used on any Apple device using your own quality earphones. A member of the American Tinnitus Association.
- Oct 2011Grant (prize money)$700K
- Sep 2011Grant (prize money)$699K
- Jun 2010Grant (prize money)$876K
- 2010Grant (prize money)—
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Disease Self Management coverage by sub-theme.
Regulatory-risk over time falling
Funding & growth over time
funding flat · growth flat
How research on Digital Health in Colorado is moving
A read on the academic research around Digital Health in Colorado — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 123 papers.
- University of Colorado Anschutz Medical Campus39
- University of Colorado Denver38
- Colorado State University15
- Colorado School of Public Health13
- University of Colorado Boulder11
- Health informatics7
- Health care4
- Informatics3
- Health administration3
- Mental health2
- Health care1→10
- Public health1→4
- Usability1→4
- Clinical decision support system1→3
- Health informatics5→6
- Health informatics1→19
- Health administration1→9
- Health care1→9
- Nursing research1→8
- Psychological intervention1→6
Common questions
Sweetie watches where the money and the users are piling in. She covers sector wealth and momentum — the install curves and revenue pools that show which corners of the market are quietly on fire.