Best Disease Self Management Companies in Germany
The 333 best Disease Self Management companies in Germany in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Ada.
Germany's Disease Self Management sector has 333 companies tracked, with $577M in total disclosed funding and not a single unicorn yet. That gap between capital deployed and breakout valuation is the story right now. Clue leads the pack at $56M raised, followed by Patronus Group at $34M and HelloBetter at $28M. So you've got a handful of funded standouts and a long tail of sub-$10M players like AssistMe and Regulate still finding their footing. The global market sits at roughly $4.8B today and, according to IMARC Group, is forecast to hit $16.8B by 2033 at a 13.4% CAGR. That's a tailwind worth paying attention to.
I'd argue the more interesting pressure point is structural. Increasing lifestyle-based diseases are driving demand faster than infrastructure can scale, and data security with rising digital connectivity is the regulatory friction every founder here has to price in. Investors like HTGF, EIT Health and German Accelerator are clearly betting on the space, but the absence of a unicorn tells you the category's still consolidating. Which company clears $100M first? Watch the funding momentum closely, because this quarter it's genuinely moving.
- ResearchAndMarkets.com
Our analysis of 50 Disease Self Management companies
$3.0b in tracked funding; 94% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Disease Self Management companies in Germany
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | App-install YoY | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Ada Provider of AI-driven personalized healthcare platform | $167M | 52 mo ago | 3 | Claire Novorol Co-Founder | WordPressApple iCloud MailMySQL+26 | — | — | — |
| 2 | Clue Provider of women-led period and cycle tracker app 62Customers top 17%Tech top 27%Funding top 29%Moat top 31% All 10 signals ▾Customerstop 17% Techtop 27% Fundingtop 29% Moattop 31% Markettop 40% Producttop 46% Growthtop 48% Talentbottom 49% Fin. healthbottom 47% Globalbottom 39% Customers: Play-Store rating 4.45★ across 1,469,482 ratings (1 apps) · Review volume +4% in 6 mo Tech: 44 technologies across 6/8 capability areas · Cloud: Amazon Cloudfront, Amazon Web Services rank vs industry peers · Fliar Intelligence Index 62/100 | $56M | 5 mo ago | 78 78 → 158 (+103%) | Rhiannon White Chief Executive Officer | Cart FunctionalityContentfulApple iCloud Mail+21 | +17% | — | 1 partnership · 1 award |
| 3 | Sapiens Neuro Developer of brain stimulation device to treat neurodegenerative disorders | $56M | 150 mo ago | 59 | Sjaak Deckers ex-CEO | — | — | — | — |
| 4 | Patronus Group Provider of software that transforms a smartwatch into a reliable companion for elderly people 62Funding top 26%Growth top 28%Tech top 38%Market bottom 49% All 6 signals ▾Fundingtop 26% Growthtop 28% Techtop 38% Marketbottom 49% Talentbottom 49% Globalbottom 39% Funding: Raised $33.8M across 3 rounds · 3 rounds over 4 yrs (0.8/yr) Growth: Web rank 50,000,000 → 10,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 62/100 | $34M | 1 mo ago | 106 | Ben Staudt Managing Director & Founder | RubyAnimate.cssTailwind CSS+18 | — | — | — |
| 5 | HelloBetter Provider of online therapy programs and an AI-based psychological support companion 80Talent top 23%Funding top 26%Tech top 28%Growth top 35% All 9 signals ▾Talenttop 23% Fundingtop 26% Techtop 28% Growthtop 35% AItop 45% Markettop 46% Producttop 46% Newsbottom 43% Globalbottom 39% Talent: 7 named leaders on record · 7 C-suite/founder profiles curated Funding: Raised $27.7M across 8 rounds · 8 rounds over 6 yrs (1.3/yr) rank vs industry peers · Fliar Intelligence Index 80/100 | $28M | 15 mo ago | 122 | Hannes Kloepper Co-Founder & CEO | SentryAlgoliaTailwind CSS+20 | — | — | — |
| 6 | Endel App for audio-based mind relaxation | $22M | 43 mo ago | 12 | Dmitry Evgrafov Co-Founder | TurbopackNode.jsFacebook Login+20 | +64% | — | — |
| 7 | DiaMonTech Developer of non-invasive blood glucose monitoring technology 53Talent top 23%Moat top 25%Innovation top 31%Patents top 34% All 10 signals ▾Talenttop 23% Moattop 25% Innovationtop 31% Patentstop 34% Fundingtop 35% Growthtop 45% Globalbottom 42% Techbottom 38% Marketbottom 34% Newsbottom 22% Talent: 5 named leaders on record · 5 C-suite/founder profiles curated Moat: Editorial + unicorn rating 7/10 · IP moat: 92 patents rank vs industry peers · Fliar Intelligence Index 53/100 | $19M | 19 mo ago | 29 | Werner Mäntele Co-Founder & Head Of Research And Development | WebflowYouTubecore-js+10 | — | 92 patents Optical spectroscopy devices for in‑tissue analyte detection and concentration monitoring | 1 internship |
| 8 | Inne Provider of an at-home fertility monitoring system for women | $19M | 48 mo ago | 14 | — | Cart FunctionalityShopifySentry+35 | — | — | 1 partnership |
| 9 | Caspar Digital therapy planning and management solution | $17M | 58 mo ago | 53 | Max von Waldenfels Co-Founder | TypeScriptZone.jsEmotion+13 | +44% | — | — |
| 10 | Cara Care Provider of a digital therapeutic app for irritable bowel syndrome | $16M | 48 mo ago | 32 32 → 52 (+62%) | Andre Summer Co-Founder | ContentfulYouTubeEmotion+22 | +4% | — | 1 job opening |
| 11 | Motion Capture Group Digital solution for chronic MSK conditions | $15M | 79 mo ago | 6 | Hartmut Voss Co-CEO and Co-Founder | — | — | 14 patents Wearable foot‑ground force sensors for precise gait analysis and biomechanics monitoring. | — |
| 12 | Selfapy Provider of digital therapeutic software for medical providers and employees | $14M | 41 mo ago | 28 | Katrin Bermbach Co-Founder | Apple iCloud MailGoogle WorkspaceTypeScript+23 | — | — | — |
| 13 | Neotiv Mobile app for brain training and tracking cognitive health | $10M | 43 mo ago | 19 19 → 42 (+121%) | — | Apple iCloud MailMicrosoft 365Zoho+14 | — | 3 patents Implantable neurovascular stimulation devices for therapeutic vascular modulation | 1 partnership |
| 14 | Sympatient Provider of virtual reality-based anxiety therapy solutions | $9M | 44 mo ago | 15 | Jan Niklas Rösch Co-Founder & CTO | WordPressPleskZoho+20 | — | 4 patents Digital therapeutic serious‑game platforms for mental‑health prevention and treatment | 1 job opening |
| 15 | CardioSecur Heart health monitoring device | $9M | 112 mo ago | 14 | — | Cart FunctionalityTYPO3 CMSOdoo+22 | — | — | — |
| 16 | EyeSense Developer of a continuous glucose monitoring system for diabetes management | $8M | 138 mo ago | 15 15 → 15 (+0%) | Achim Muller Managing Director | — | — | 80 patents Continuous transcutaneous glucose biosensor implantation and monitoring systems | 1 partnership |
| 17 | Libify A mobile emergency call system | $7M | 92 mo ago | 55 | — | HubSpot CMS HubEnvoyBootstrap+18 | — | — | — |
| 18 | AssistMe Developer of IoT enabled solution to combat incontinence 42Innovation top 29%Patents top 32%Growth top 35%Moat top 38% All 9 signals ▾Innovationtop 29% Patentstop 32% Growthtop 35% Moattop 38% Fundingtop 43% Productbottom 48% Techbottom 36% Globalbottom 33% Marketbottom 28% Innovation: 20 patents (top 45% of patent-holders) · 20 filings since 2022 vs 0 in 2017-21 Patents: 20 patents matched (strict assignee match) · 20 filings since 2022 vs 0 in 2017-21 rank vs industry peers · Fliar Intelligence Index 42/100 | $6M | 10 mo ago | 25 | — | WordPressMySQLPHP+17 | — | 20 patents Smart incontinence detection and assembly technologies for absorbent hygiene products | — |
| 19 | Clare Provider of AI-enabled voice assistant tool for psychological health | $5M | 22 mo ago | 20 | Celina Messner Co-Founder | Webflow EcommerceWebflowcore-js+16 | — | — | — |
| 20 | VisionHealth Developer of digital health solutions for optimized inhalation therapy administration | $5M | 39 mo ago | 22 22 → 14 (-36%) | Philipp Kroneberg Co-Founder & COO | WordPressPleskMySQL+18 | — | 3 patents Inhaler training devices and simulation software for respiratory therapy | — |
| 21 | Memorado Memory and Brain training app | $5M | 134 mo ago | 5 | — | FirebaseAnimate.cssBootstrap+16 | — | — | — |
| 22 | Seroton Provider of an app controlled device with integrated relaxation techniques and massage patterns 48Talent top 35%Tech top 47%Funding bottom 44%Product bottom 40% All 5 signals ▾Talenttop 35% Techtop 47% Fundingbottom 44% Productbottom 40% Globalbottom 25% Talent: 3 named leaders on record Tech: 25 technologies across 4/8 capability areas · Cloud: Cloudflare rank vs industry peers · Fliar Intelligence Index 48/100 | $4M | 15 mo ago | — | Nico Vogler Co-Founder | Cart FunctionalityShopifyVisa+18 | — | — | 2 awards |
| 23 | Nia Health Provider of digital therapeutics for personalized patient support in dermatology and allergology | $4M | 36 mo ago | — | Oliver Welter Co-Founder | WordPressMySQLPHP+19 | — | — | — |
| 24 | Keleya App offering exercise and yoga plans for pregnant women | $3M | 56 mo ago | 18 18 → 25 (+39%) | Alexander Leuchte Co-Founder | Cart FunctionalitySentryZendesk+19 | +28% | — | 1 job opening |
| 25 | Aumio Provider of an application for childs meditation and sleep | $3M | 49 mo ago | — | Tilman Wiewinner Co-Founder | Cart FunctionalityShopifyVisa+15 | — | — | 1 job opening |
| 26 | Preventicus Developer of medical technologies and care programs for heart health | $3M | 58 mo ago | 26 26 → 34 (+31%) | — | WordPressApple iCloud MailMicrosoft 365+27 | +25% | 30 patents Real-time physiological monitoring and analysis of cardiovascular biomarkers. | 1 launch |
| 27 | SwiftAlarm App offering personal emergency response system | $3M | 88 mo ago | — | Rudolf C King Founder | — | — | — | — |
| 28 | Emperra Glucose monitoring system - devices and connected mobile & web apps | $3M | 125 mo ago | 11 | — | — | — | — | — |
| 29 | Lilio Provider of baby monitoring devices for parents to understand the childs needs | $2M | 30 mo ago | — | Nadine Wunderlich Co-Founder & CEO | — | — | — | — |
| 30 | brainjo AI based plafrom providing cognitive training 21AI top 35%Funding top 44%Talent bottom 49%Product bottom 45% All 7 signals ▾AItop 35% Fundingtop 44% Talentbottom 49% Productbottom 45% Globalbottom 32% Techbottom 31% Marketbottom 22% AI: Product described with: ai based, ai-based Funding: Raised $2.4M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 21/100 | $2M | 1 mo ago | — | Christian Gnerlich Founder | MyWebsiteDudaMyWebsite Creator+10 | — | — | — |
| 31 | iATROS Provider of mobile app to monitor vital health | $2M | 75 mo ago | 47 | — | Webflow EcommerceWebflowTypeScript+21 | — | — | — |
| 32 | DIPAT Online platform for creating wills and storing emergency data | $2M | 110 mo ago | 4 | — | ContaoApple iCloud MailGoogle Workspace+19 | — | — | — |
| 33 | Niostem Provider of smart wearable device to regrow hair | $2M | 53 mo ago | 9 | Emil Aliev Co-Founder | Cart FunctionalityShopifyBootstrap+33 | — | — | — |
| 34 | smedo Provider of body vital measuring device | $2M | 49 mo ago | 8 | Thomas Grellner Founder & CEO & MD | — | — | — | — |
| 35 | Regulate Provider of an AI-powered platform that provides personalized support for mental performance, emotional… 53AI top 45%Funding top 49%Talent bottom 49%Global bottom 48% All 5 signals ▾AItop 45% Fundingtop 49% Talentbottom 49% Globalbottom 48% Productbottom 40% AI: Product described with: ai-powered Funding: Raised $1.6M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 53/100 | $2M | 1 mo ago | — | Peter Woerkum Founder | — | — | — | — |
| 36 | inContAlert Developer of wearable sensor technology for bladder monitoring and management | $2M | 33 mo ago | 15 | Jannik Lockl Co-Founder | WordPressMySQLPHP+24 | — | 6 patents Non‑invasive urinary bladder volume monitoring devices for patient hydration management | — |
| 37 | Flow Lab Provider of mobile app for mental health management | $1M | 60 mo ago | 8 | Peter Schwarz Co-Founder | WordPressMySQLPHP+17 | — | — | — |
| 38 | xbird Provider of AI-based solutions for diagnosis and health risk assessment | $1M | 69 mo ago | 21 | — | — | — | — | — |
| 39 | Vivira Provider of digital therapeutic application for back pain management and relief | $1M | 110 mo ago | 45 | Fabian Blank Co-Founder | TYPO3 CMSApple iCloud MailGoogle Workspace+14 | — | — | — |
| 40 | HERMONE Mobile application offering information and tracking menstrual cycle symptoms | $1M | 39 mo ago | 5 | Lucia Vilsecker Co-Founder & CEO | — | — | — | — |
| 41 | Connected health Local Exchange of medical data with the doctor | $1M | 113 mo ago | — | Matthias Lau Co-Founder & CTO | — | — | — | — |
| 42 | IEM Portfolio of devices and software for hypertension management | $759K | 65 mo ago | — | Uwe Korth CEO | OdooPostgreSQLFirebase+9 | — | — | 2 partnerships |
| 43 | Mediteo Provider of mobile app for medication management | $573K | 65 mo ago | — | — | WordPressBetterDocsMySQL+19 | +18% | — | — |
| 44 | heyvie Online platform for managing migraine pain | $464K | 56 mo ago | 4 | Marius Kramer Co-Founder & Managing Director | — | — | — | — |
| 45 | movisens Manufacturer of activity sensors for ambulatory assessment and mobile monitoring applications | $449K | 62 mo ago | — | Ulrich Grobmann Co-CEO | Cart FunctionalityWooCommerceWordPress+20 | — | 6 patents Wearable bioimpedance and heart‑rate sensing belts for continuous physiological monitoring | 1 launch · 1 award |
| 46 | memodio Mobile app offering cognitive training | $436K | 40 mo ago | 10 | Doron Stein Co-Founder & CEO | WordPressMySQLPHP+12 | — | — | — |
| 47 | BOOST Thyroid Provider of personalised app for managing thyroid disorders | $370K | 64 mo ago | 2 | Mikael Hogqvist Tabor Co-Founder | — | — | — | — |
| 48 | CogniScent Provider of AI-based platform for early detection of neurodegenerative diseases | $355K | 72 mo ago | 2 | Micol Ruvo Co-Founder & CTO | — | — | — | — |
| 49 | Medipee Developer of a contactless and automated urinalysis system | $249K | 62 mo ago | 10 | — | WordPressApple iCloud MailMySQL+15 | — | 32 patents Real-time urinary diagnostics and micturition monitoring using test strips and sensor devices | — |
| 50 | Enuncia.ai AI powered platform offering speech therapy app | $160K | 26 mo ago | — | Julius Behner Founder & CEO | — | — | — | — |
Top 12 Disease Self Management companies in Germany
#1
Series A · Berlin, Berlin · founded 2021 · 106 employees$33.8Mraised▾
Provider of software that transforms a smartwatch into a reliable companion for elderly people. The software allows older adults at risk to call for help anytime and anywhere with a built-in call function. It helps the elderly to live safely and independently while staying connected to their families.
- Apr 2026Series A$12.9M
- Oct 2022Series A$26.8M
- May 2022Seed$7M
#2
Series B · Berlin, Berlin · founded 2012 · 78 employees$56Mraised▾
Provider of women-led period and cycle tracker app. The application offers cycle statistics and predictions. It provides tracking modes based on individual needs. The application allows users to share cycles with partners.
- Jan 2026Series B—
- Apr 2023Series B$7.6M
- Dec 2021Series B$18M
- Nov 2016Series B$20M
#3
Seed · Regensburg, Bavaria · founded 2019$2.4Mraised▾
Brainjo is an AI-based platform that provides cognitive training. The company tests the physical and cognitive performance of the individual and set personal goals. It creates a personal training plan for physical-mental training. It provides training like reaction training, neurofeedback, and brain jogging.
- Apr 2026Seed$2.4M
#4
Seed · Munich, Bavaria · founded 2008$1.6Mraised▾
Provider of an AI-powered platform that provides personalized support for mental performance, emotional regulation, and wellness. It offers science-based breathwork sessions to achieve desired mental, physical, and emotional state.
- May 2026Seed$1.6M
#5
Series B · Hamburg, Hamburg · founded 2015 · 122 employees$27.7Mraised▾
Provider of online therapy programs and an AI-based psychological support companion. The company offers various programs addressing conditions like burnout, sleep issues, and anxiety. It also provides an AI companion for emotional support and self-reflection. The programs are developed by psychotherapists and aim to provide accessible mental healthcare.
- Mar 2025Series B$6.4M
- Nov 2024Conventional Debt—
- Nov 2024Grant (prize money)$3.2M
- Sep 2023Series A$5.3M
#6
Series A · Berlin, Berlin · founded 2018 · 25 employees$6.1Mraised▾
AssistMe develops Internet of Things enabled solutions for healthcare applications. Its chief offering AidMate is a smart incontinence pant that comes with intelligent algorithms for detecting abnormal patterns and medical problems while predicting issues and harmful behavior. Additionally, the solution can be used for monitoring parameters like heart rate, breathing rate, temperature, sleep patterns, to name a few. It also allows integrating third-party devices to the solution for creating a holistic care ecosystem.
- Aug 2025Series A$6.1M
#7
Series A · Berlin, Berlin · founded 2015 · 29 employees$19.2Mraised▾
Developer of non-invasive blood glucose monitoring technology. This technology utilizes a novel laser-based method to measure glucose levels in interstitial fluid, eliminating the need for needles or test strips. The company is developing a handheld device for consumer use and a miniaturized sensor for integration into other devices. The technology is currently undergoing clinical trials and regulatory processes before market launch. A companion app is also under development to track glucose levels, along with other health data.
- Nov 2024Series A—
- Dec 2023Series A—
- Feb 2022Series A$5.7M
- Sep 2019Series A$7.7M
#8
Seed · Gunzenhausen, Bavaria · founded 2023$4.1Mraised▾
Seroton delivers immersive relaxation experiences by combining haptic feedback with sound, helping people deeply relax and recover in their everyday environments. Its app-controlled platform offers personalized relaxation sessions with synchronized haptic patterns, seamlessly integrated into loungers and mats for homes, workspaces, hotels and clinics. Acting as a smart control hub, the app curates adaptive sessions that adjust to each user’s mood, goals and schedule, making effective relaxation both accessible and measurable in daily life.
- Feb 2025Seed$1.6M
- Jan 2024Seed$2.5M
#9
Series A · Germany · founded 2021 · 20 employees$5.2Mraised▾
Provider of AI-enabled voice assistant tool for psychological health. It provides users with a voice assistant tool that allows them to seek help for mental-health-related difficulties over the phone or through text messaging.
- Aug 2024Series A$4M
- Feb 2022Seed$1.1M
- 2021Seed—
#10
Series B · Berlin, Berlin · founded 2011 · 3 employees$167Mraised▾
Provider of AI-driven personalized healthcare platform. Its virtual application allows users to ask questions and describe their symptoms to a chatbot which then provides feedback and medical advice, it also enables the user with a follow-up remote consultation with a real doctor over text. It features a medical library for giving more detailed information on health management and help in the storage and sharing of their medical records.
- Feb 2022Series B$30M
- May 2021Series B$90.5M
- Nov 2018Series A—
- Oct 2017Series A$46.5M
#11
Series B · Berlin, Berlin · founded 2017 · 12 employees$22.1Mraised▾
Endel offers an app for audio-based mind relaxation. The app offers algorithm-based personalized tunes which alter according to the environmental conditions. The app can be used at home, work, and public space environments. The enables users to focus & concentrate at work, to relax & sleep at home and comfort in a public space.
- Nov 2022Grant (prize money)$257.2K
- Apr 2022Series B$15M
- Sep 2020Series A$5M
- Sep 2018Seed$1.3M
#12
Series A · Berlin, Berlin · founded 2016 · 28 employees$14.1Mraised▾
Provider of digital therapeutic software for medical providers and employees. The company has developed an online platform that enables patients and employees to get mental therapeutic courses, services, and programs. It allows doctors, therapists, and business companies to offer online courses on mental health management for patients/employees. The platform has different courses for chronic pain, panic, depression, stress, and more.
- Dec 2022Series A$7.4M
- Feb 2020Series A$6.6M
- 2018Seed—
- Aug 2017Seed—
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Disease Self Management coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health is moving in Germany
A read on the academic research around Digital Health — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,976 Germany-affiliated papers.
- Charité - Universitätsmedizin Berlin161
- Heidelberg University147
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin82
- Technical University of Munich76
- Friedrich-Alexander-Universität Erlangen-Nürnberg73
- Health informatics1→28
- Wearable computer3→18
- Context (archaeology)1→11
- Photoplethysmogram1→10
- Psychological intervention1→8
- Health informatics8→118
- Health care5→106
- Public health2→60
- Psychological intervention2→60
- Intervention (counseling)1→49
- Health care11→278
- Health informatics31→192
- Public health14→120
- Psychological intervention2→91
- Health administration24→100
Where digital health is researched across Germany
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing digital health patents in Germany
Germany digital health patent filing is accelerating — 50 filings from 50 assignees (2016–2025), led by Robert Bosch, Airbus Operations, Liebherr Aerospace Lindenberg; annual filings 5→6.
- Robert Bosch16
- Airbus Operations11
- Liebherr Aerospace Lindenberg9
- FENG ZHE6
- Hasan Taufiq6
- WENG Fuliang6
- NEC Laboratories Europe3
- Lotus TECH Innovation Centre3
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.