Best Disease Self Management Companies in Israel
The 287 best Disease Self Management companies in Israel in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Vayyar.
Israel's Disease Self Management sector has a funding story worth reading straight. Our directory tracks 287 companies in Israel with $1.1 billion in total disclosed funding, and the spread between filers tells you everything: Vayyar sits at $296 million while Neurolief has raised $11 million and OneStep $48 million, meaning a single outlier holds roughly a quarter of the sector's entire capital base. One unicorn. Real concentration.
So what does the market underneath all that funding actually look like? The global Disease Self Management market was valued at approximately $4.8 billion in 2023 and is forecast to reach $16.8 billion by 2033, a CAGR of 13.4%, driven by rising lifestyle-based diseases and the shift toward digital, online management solutions. I'd flag one structural pressure you can't ignore: as connectivity deepens, ensuring data security and privacy becomes a harder compliance problem for every company in this directory. Active backers here include Europa, MassChallenge, and Israel Brain Technologies, which signals that institutional appetite hasn't dried up. The funding is real. The growth math is compelling. The question is which of these 287 companies captures it.
- ResearchAndMarkets.com
Our analysis of 50 Disease Self Management companies
$3.0b in tracked funding; 94% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Disease Self Management companies in Israel
| # | Company | Disclosed funding | Last round | Stage | Employees | Founder | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Vayyar 🦄 Developer of 4D imaging sensors for cancer detection and other devices | $296M | 48 mo ago | Series E | 330 | Raviv Melamed Co-Founder & CEO | Top 5M | — | — |
| 2 | Intuition Robotics Provider of an AI-based social robot that acts as a companion for the elderly | $83M | 33 mo ago | Series C | 74 | — | Top 10M | 54 patents Adaptive human‑robot interaction: user availability detection, emotional gestures, personalized device behavior | — |
| 3 | Lumen Provider of metabolism tracker for a diet plan | $78M | 42 mo ago | Series B | 1 | Merav Mor Co-Founder | Top 500k | — | — |
| 4 | Cnoga Medical Developer of noninvasive medical devices and remote patient monitoring solutions. | $70M | 111 mo ago | Series C | 27 | — | Top 5M | 55 patents Non‑invasive cardiovascular and metabolic monitoring via ECG, optical, and camera sensing | — |
| 5 | NUVO Developer of cloud-based maternal-fetal monitoring sensors | $55M | 59 mo ago | Series B | 72 | — | Top 50M | 137 patents Prenatal bio-potential sensing and fetal/maternal uterine activity monitoring devices | 1 launch |
| 6 | BrainQ Developer of AI-powered electromagnetic stimulation technology for stroke disability recovery | $49M | 53 mo ago | Series B | 44 | Yaron Segal Founder & CTO | Top 10M | 3 patents Non‑invasive electromagnetic neurostimulation for nerve regeneration and repair | — |
| 7 | OneStep Mobile-based application for physical therapy | $48M | 19 mo ago | Series B | 48 | Shahar Davidson Co-Founder & CTO | Top 5M | — | 1 launch |
| 8 | G Medical Innovations Provider of a suite of devices for vital signs monitoring | $41M | 31 mo ago | Public | 74 | — | — | 164 patents Wearable thoracic impedance monitoring systems for fluid and respiratory diagnostics | — |
| 9 | OrSense Provider of non-invasive sensing technology for body vitals measurement | $33M | 181 mo ago | Series B | 24 | Yoav Reisman CEO | Top 50M | 60 patents Non‑invasive optical spectroscopy for measuring blood analytes and physiological parameters. | — |
| 10 | Sweetch AI-based mobile app for disease risk prediction solution through behavior modification | $30M | 59 mo ago | Series A | 49 | Yossi Bahagon Chief Executive Officer | Top 50M | — | — |
| 11 | GluSense Implantable Glucose level sensor for Type 1 Diabetes patients | $27M | 112 mo ago | Deadpooled | 6 | — | — | 36 patents FRET-based continuous glucose biosensors for implantable, real-time analyte monitoring | — |
| 12 | Medasense Non-invasive pain-monitoring device | $27M | 68 mo ago | Series C | 27 | Galit Stark Founder & CEO | Top 10M | — | 1 partnership |
| 13 | HAGAR Developer of a non-invasive glucometer device for diabetes patients | $25M | 34 mo ago | Series C | — | Guy Zur Co-Founder & CEO | Top 50M | — | — |
| 14 | ElliQ Provider of an Artificial Intelligence driven social robot | $22M | 101 mo ago | Series A | — | Roy Amir Co-Founder | Top 5M | — | — |
| 15 | ContinUse Biometrics Contactless biometric sensor for the continuous monitoring of biomedical parameters | $21M | 99 mo ago | Series B | 12 | — | — | 80 patents Patents concentrated in computing, sensing & instrumentation | — |
| 16 | Uniper care Digital care planning in management tool for elder individuals | $19M | 59 mo ago | Series A | 65 | Rami Kirshblum Co-Founder & CEO | Top 10M | — | 5 job openings · 1 partnership |
| 17 | Cordio Medical Monitoring chronic heart failure through free speech into a smartphone app | $18M | 53 mo ago | Series A | 30 | Aviv Lotan Co-Founder | Top 50M | 121 patents Voice-based health diagnostics and physiological monitoring through speech analysis | — |
| 18 | KeePAP Provider of wearable device to monitor sleep apnea | $15M | 68 mo ago | Series C | — | Alex Rapoport Founder & CEO | — | — | — |
| 19 | CardiacSense Provider of sensor to monitor heart arrhythmia and vital signs | $14M | 72 mo ago | Series B | 40 | Eldad Shemesh Co-Founder And Ceo | Top 5M | 58 patents Wearable cardiac and oxygen saturation monitoring devices for continuous physiological tracking | — |
| 20 | Vectorious Medical Tech Implant for left-atrial monitoring | $14M | 74 mo ago | Acquired | 69 | — | Top 10M | — | — |
| 21 | Binah.ai Provider of a video-based health and wellness monitoring system | $14M | 72 mo ago | Series B | 65 | Konstantin Gedalin Co-Founder | Top 5M | 24 patents Non‑invasive optical measurement of blood pressure, pulse transit time, and alcohol levels | 1 launch |
| 22 | GlassesOff Online program to improve near vision sharpness and reading capabilities | $13M | 128 mo ago | Late Stage | 25 | Nimrod Madar CEO and President | Top 50M | — | — |
| 23 | Neurolief Wearable device for neurological and neuropsychiatric disorders 27Patents top 36%Talent top 38%Innovation top 39%Funding top 46% All 10 signals ▾Patentstop 36% Talenttop 38% Innovationtop 39% Fundingtop 46% Producttop 47% Moattop 47% Globalbottom 35% Marketbottom 28% Techbottom 26% Newsbottom 22% Patents: 55 patents matched (strict assignee match) · 18 filings since 2022 vs 29 in 2017-21 Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 27/100 | $11M | 2 mo ago | Series A | — | Shmuel Shany Co-Founder | Top 50M | 55 patents Wearable transdermal neurostimulation headsets integrating biosensing for therapeutic monitoring | 1 job opening |
| 24 | 6over6 Mobile apps for optometry | $11M | 102 mo ago | Acquired | 130 | — | Top 50M | — | — |
| 25 | Kyma Remote patient monitoring solutions for chronic cardiac patients | $10M | 152 mo ago | Acqui-Hired | 11 | Uriel Weinstein Co-founder | — | — | — |
| 26 | Olive Diagnostics AI and home-based urinalyses sensor for disease diagnosis | $7M | 45 mo ago | Seed | 28 | Guy Goldman Co-Founder & CEO | — | 6 patents Real-time urine analysis integrated into home toilet for health monitoring | — |
| 27 | HeraMED Developer of remote maternity monitoring platform and related smart devices | $7M | 30 mo ago | Public | 21 | — | Top 5M | — | 2 launchs · 1 award |
| 28 | XTrodes Wearables to monitor mental wellness | $6M | 31 mo ago | Seed | 21 | David Rand Co-Founder | Top 10M | — | 1 launch |
| 29 | Nevia Bio Machine learning-enabled platform for early detection of women-related diseases | $5M | 33 mo ago | Seed | 8 | Inbal ZafirLavie Co-Founder & CEO | — | — | — |
| 30 | WideMed Web-based sleep monitoring platform for the diagnosis of sleep disorders | $5M | 258 mo ago | Public | — | Bar-Lev Yaacov Owner & Ceo & Chairman Of The Board | — | 44 patents Non-invasive monitoring and analysis of cardiac and respiratory signals via photoplethysmography | — |
| 31 | VOTIS AI-based device and platform for diagnosing diabetic patient feet | $5M | 37 mo ago | Seed | 16 | — | — | — | — |
| 32 | FertilAI AI-based platform for monitoring fertility | $4M | 18 mo ago | Seed | 8 | — | Top 50M | 3 patents AI-based precise ovulation date prediction for fertility and reproductive health | 1 launch · 1 partnership |
| 33 | Innovision Labs Company providing consumer-facing solutions using visual neuroscience. | $4M | 128 mo ago | Deadpooled | 19 | Nimrod Madar CEO & President | — | — | — |
| 34 | Bosco Kids' smartphone activity monitoring awareness app for parents | $4M | 94 mo ago | Series A | 6 | Enon Landenberg Co-Founder | — | — | — |
| 35 | Reflect Developer of smart device for stress and anxiety management | $3M | 63 mo ago | Seed | 9 | Noga Sapir Founder & CEO | Top 10M | — | — |
| 36 | Oxitone Wrist-based Pulse Oximetry health monitor | $3M | 133 mo ago | Seed | 11 | Leon Eisen Founder & Executive Chairman | Top 50M | — | — |
| 37 | IMMA Health Provider of ovulation stimulation monitoring system 29Talent top 38%Funding bottom 43%Global bottom 36% All 3 signals ▾Talenttop 38% Fundingbottom 43% Globalbottom 36% Talent: 2 named leaders on record · 2 C-suite/founder profiles curated Funding: Raised $2.5M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 29/100 | $2M | 9 mo ago | Seed | — | Beatrice Chemla Co Founder And Ceo | — | — | — |
| 38 | BSP Medical Developer of ECG devices for Ischemic heart disease | $2M | 121 mo ago | Public | — | Amir Beker Founder | — | — | — |
| 39 | iRen Medical Provider of remote dialysis services and self-care solutions | $2M | 81 mo ago | Funding Raised | 8 | Hezkiah Tsoory Co-Founder & CEO | — | — | — |
| 40 | Sanolla Developer of AI-based digital diagnostics systems to detect multiple diseases | $2M | 66 mo ago | Funding Raised | 18 | Dudu Linhard Co-Founder | — | 21 patents Patents concentrated in health & consumer products | — |
| 41 | SayVU Safety app to enable quick emergency services | $2M | 118 mo ago | Seed | 13 | — | — | — | — |
| 42 | NeuroTrigger Provider of a wearable muscle re-eductaion stimulator | $2M | 8 mo ago | Seed | 4 | Hagit Deutsch Co-Founder | — | 21 patents Wearable magnetic‑connector electrodes for transcutaneous facial nerve stimulation | — |
| 43 | BioLert Smartwatch wearable for the detection of epilepsy seizures | $2M | 174 mo ago | Funding Raised | — | Avi Yaron CEO | — | 7 patents Wearable medical devices for real-time epileptic seizure detection and monitoring. | — |
| 44 | EchoCare Provider of remote monitoring solution for senior safety and well-being | $1M | 86 mo ago | Series A | — | Rafi Zack Founder | — | — | — |
| 45 | Intendu Kinect-based motor rehabilitation solution | $1M | 106 mo ago | Deadpooled | 7 | — | — | 2 patents Neurocognitive training and assessment platforms for brain health monitoring | — |
| 46 | Biobeat Body vitals monitoring solution 48Tech top 34%Growth top 35%Product top 40%Funding top 46% All 7 signals ▾Techtop 34% Growthtop 35% Producttop 40% Fundingtop 46% Moattop 48% Globalbottom 38% Marketbottom 37% Tech: 38 technologies across 5/8 capability areas · Cloud: Amazon Web Services, Cloudflare Growth: Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 48/100 | $1M | 5 mo ago | Series B | 29 | — | Top 5M | — | 1 expansion |
| 47 | Nehora Photonics Sensor and algorithms to non-invasively and continuously monitor Hematocrit | $780K | 179 mo ago | Deadpooled | 11 | David Frank Chairman & CEO | — | — | — |
| 48 | QuLab Medical Developer of minimally-invasive continuous glucose monitoring system | $750K | 40 mo ago | Funding Raised | 8 | Idan Tamir CEO | — | 38 patents Electrochemical FET biosensors for point‑of‑care medical diagnostics | — |
| 49 | Prana Essentials Personalized recommendation system for diet, physical activity, stress management & wellness | $575K | 132 mo ago | Deadpooled | 8 | Yaron Meerfeld Founder & CEO | — | 3 patents AI-driven personalized nutraceutical and supplement recommendation platform | — |
| 50 | AmnioTix Medical Spectroscopy-based medical device for the assessment of fetal well-being | $550K | 192 mo ago | Deadpooled | — | Ehud Nachtomy CEO | — | — | — |
Top 12 Disease Self Management companies in Israel
#1
Series A · Herzliya, Tel Aviv · founded 2012$11Mraised▾
Neurolief is focussed on developing a wearable platform technology for brain neuromodulation. It is developing a wearable device that enables the safe and effective treatment for neuro disorders such as migraine and depression without interfering with the patient's daily activities. As of September 2016, the device is in clinical development.
- Mar 2026Series A$6M
- Aug 2025Series A$5M
- 2015Seed—
#2
Series B · Tel Aviv, Tel Aviv · founded 2010 · 48 employees$48Mraised▾
Mobile-based application for physical therapy. The platform provides virtual physical therapy for stroke recovery, pre-and post-operative joint replacement recovery, and broken bones. Users can perform the regular exercises and receives real-time feedback and personalized insights for improvement.
- Oct 2024Series B$36M
#3
Series B · Petah Tikva, Central District · founded 2014 · 29 employees$1Mraised▾
Biobeat offers a non-invasive body vitals monitoring wearable solution. It uses reflective Pulse Oximetry technology with their algorithm to allow for constant measurements of related body vitals. Sensor delivers a range of body vitals measurement including consciousness, saturation, pulse, temperature and perspiration. The devices are connected to a mobile app or a central monitoring system where the user's data is stored. Data is then compared against a person's normal levels to identify life-threatening situations. It also allows data sharing with doctors and caregivers. They have released their products for athletes and Hospitals. Founded by Arik Ben Ishai Director of startups in the Rocket and Space Department of the Ministry of Defense, Israel.
- Dec 2025Series B$50M
- Oct 2019Grant (prize money)$188.5K
- Jun 2016Angel$1M
#4
Seed · Tel Aviv, Tel Aviv · founded 2018 · 4 employees$1.7Mraised▾
Provider of a wearable muscle re-eductaion stimulator. The company develops the next-generation wearable powered muscle re-education stimulation system for facilitating and improving muscle performance and muscle range of motion and for the prevention or retardation of disuse atrophy.
- Oct 2025Seed$725K
- Dec 2024Seed$520K
- Jul 2023Seed$1.7M
#5
Seed · Ra'anana, Central District · founded 2020$2.5Mraised▾
Provider of ovulation stimulation monitoring system. The company has developed an ultrasound like device for women to diagnose and monitor follicle stimulation and fertility status.
- Sep 2025Seed$2.5M
- Sep 2025Grant (prize money)—
#6
Vayyar 🦄Series E · Yehud, Center District · founded 2011 · 330 employees$296Mraised▾
Developer of 4D imaging sensors for cancer detection and other devices. It offers a hand-held screening device that generates high-resolution 3D images that detect breast cancer by using radio frequency technology. Also, it develops touchless fall detection for seniors. It provides various products for multiple industries such as retail, public safety, robotics, and smart buildings.
- Jun 2022Series E$108M
- Nov 2019Series D$109M
- Dec 2017Series C$45M
- Dec 2015Series B$22M
#7
Series C · Tel Aviv, Tel Aviv · founded 2015 · 74 employees$83Mraised▾
Provider of an AI-based social robot that acts as a companion for the elderly. The robot is a tabletop object with a screen and is equipped with the capability for video chat and voice commands. It can provide proactive commands and entertain the user.
- Aug 2023Venture Debt$5M
- Aug 2023Series C$20M
- Feb 2020Series B$36M
- Dec 2017Series A$6M
#8
Seed · Tel Aviv, Tel Aviv · founded 2020 · 8 employees$4.5Mraised▾
AI-based platform for monitoring fertility
- Nov 2024Seed$4.5M
#9
Public · Rehovot, Central District · founded 2014 · 74 employees$41.3Mraised▾
Provider of a suite of devices for vital signs monitoring. The company offers a range of consumer and Hospital grade medical devices for early detection and diagnosis of patients as well as remote monitoring. The company offers prizma G2, a smartphone case transforming any smartphone into a medical monitoring and diagnostic smartphone that captures a wide range of vital signs. The mobile application helps to collects and analyses medical data and determines correlations between tests. The company also offers – G MEDICAL PATCH (GMP), a bio-sensor monitoring system, which can be used in hospital care and post-discharge programs for continuous, real-time monitoring.
- Oct 2023Post IPO$500K
- Apr 2022Post IPO—
- Jan 2022Post IPO—
- May 2020Series B$6M
#10
Series B · Ramat Hasharon, Tel Aviv District · founded 2014 · 1 employees$77.5Mraised▾
Provider of metabolism tracker for a diet plan. The device is breath monitoring-based and provides personalized data on the mobile app, for carbohydrates and fats to monitor the body metabolism and diet plan for weight loss and overall fitness.
- Dec 2022Series B$62M
- Sep 2019Series B$8.5M
- Jul 2018Series A$7M
- Nov 2017Seed—
#11
Series C · Tel Aviv, Tel Aviv · founded 2017$25Mraised▾
Developer of a non-invasive glucometer device for diabetes patients. The company's device utilizes radiofrequency waves to continuously measure glucose levels in the blood. The device is integrated with a smartphone application to track glucose readings.
- Aug 2023Series C$5M
- Aug 2021Series B$11.7M
- Mar 2021Series A$4.4M
#12
Series B · Jerusalem, Jerusalem District · founded 2011 · 44 employees$48.8Mraised▾
Developer of AI-powered electromagnetic stimulation technology for stroke disability recovery. The investigational therapy uses tailored, low-intensity, low-frequency electromagnetic stimulation to enhance the brain’s recovery process. The device is designed for safe use in clinical and home settings. The therapy aims to help patients regain independence and improve neurological conditions.
- Dec 2021Grant (prize money)$56.6K
- Aug 2021Series B$40M
- Jan 2020Grant (prize money)$2.5M
- Nov 2018Grant (prize money)$56.9K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Disease Self Management coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health is moving in Israel
A read on the academic research around Digital Health — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 238 Israel-affiliated papers.
- Ben-Gurion University of the Negev36
- Hadassah Medical Center30
- Tel Aviv University30
- University of Haifa23
- Hebrew University of Jerusalem22
- Health care5
- Remote patient monitoring3
- Knowledge management2
- Vital signs2
- Scalp2
- Health care1→14
- Public health1→9
- Health care2→36
- Public health1→29
- Health services research1→22
- Health administration1→21
- Health informatics2→15
Where digital health is researched across Israel
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.