Best Disease Self Management Companies in Ohio, United States
The 38 best Disease Self Management companies in Ohio, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: SPR Therapeutics.
Our analysis of 50 Disease Self Management companies
$3.0b in tracked funding; 94% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Disease Self Management companies in Ohio
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | SPR Therapeutics Peripheral nerve stimulation therapy for treating pain | $174M | 31 mo ago | 198 | 2010 | Maria E Bennett Founder & CEO | — | 220 patents Implantable neurostimulation systems for chronic and back pain relief | — |
| 2 | Neuros Medical Neurostimulation therapy for chronic neuropathic pain 40Funding top 18%Moat top 31%Growth top 48%Tech top 49% All 8 signals ▾Fundingtop 18% Moattop 31% Growthtop 48% Techtop 49% Talentbottom 49% Globalbottom 39% Marketbottom 31% Newsbottom 22% Funding: Raised $89.2M across 14 rounds · 14 rounds over 17 yrs (0.8/yr) Moat: Editorial + unicorn rating 8/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 40/100 | $89M | 14 mo ago | 28 28 → 53 (+89%) | 2008 | David Veino CEO | WordPressSentryApple iCloud Mail+24 | — | — |
| 3 | Include Health Provider of therapy solutions for the treatment of musculoskeletal pain | $22M | 22 mo ago | 13 | 2006 | Ryan Eder Founder & CEO | — | — | — |
| 4 | Redi Mobile-based application of medication adherence management 27Funding top 31%Innovation top 40%Product top 49%Tech top 50% All 9 signals ▾Fundingtop 31% Innovationtop 40% Producttop 49% Techtop 50% Talentbottom 49% Globalbottom 29% Marketbottom 24% Newsbottom 24% Customersbottom 11% Funding: Raised $17.7M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) Innovation: 2 new-product events in 24 mo rank vs industry peers · Fliar Intelligence Index 27/100 | $18M | 13 mo ago | 20 | 2021 | Nate Rehm Co-Founder and Head of Business Development | SanityTurbopackNode.js+15 | — | — |
| 5 | Eccrine Systems Developer of wearable electronic wearable systems to sweat biomarkers | $15M | 82 mo ago | 56 | 2013 | Gavi Begtrup CEO | — | — | — |
| 6 | NeuroWave Systems Neurodiagnostic device and accessories | $13M | 86 mo ago | 15 | 2003 | — | Apache HTTP ServerStatcounterGoogle Analytics+2 | — | — |
| 7 | ExactCare Pharmacy Medication management and pharmacy care provider for complex medical needs | $7M | 120 mo ago | 512 512 → 445 (-13%) | 2009 | Dale Wollschleger Founder & CEO | WordPressApple iCloud MailMySQL+22 | — | — |
| 8 | Aptatek Biosciences Developer of a medical device for monitoring patients with phenylketonuria 10Talent top 28%Funding top 48%Global bottom 38%News bottom 22% All 5 signals ▾Talenttop 28% Fundingtop 48% Globalbottom 38% Newsbottom 22% Marketbottom 10% Talent: Analyst team rating 5/5 · 2 named leaders on record Funding: Raised $4.0M across 1 rounds · 1 rounds over 4 yrs (0.2/yr) rank vs industry peers · Fliar Intelligence Index 10/100 | $4M | 15 mo ago | 3 | 2008 | Tilla Worgall Co-Founder | — | — | — |
| 9 | LifeBio Provider of social platform for the elderly | $4M | 17 mo ago | 18 | 2001 | Beth Sanders Founder & CEO | UmbracoMicrosoft ASP.NETVimeo+19 | — | — |
| 10 | Kilele Health Provider of wearable remote monitoring platform for cardiometabolic chronic diseases | $3M | 11 mo ago | 4 | 2021 | Jason Heikenfeld Co-Founder | — | — | — |
| 11 | TegoSens Developer of remote monitoring device for heart failures | $2M | 67 mo ago | 4 | 2020 | Emre Ertin Co-Founder | — | 7 patents Chest-mounted medical sensor positioning devices for precise physiological monitoring | — |
| 12 | MedaCheck HIPAA compliant platform empowering Health IT with secure, customizable data solutions | $1M | 139 mo ago | 3 | 2012 | — | — | — | — |
| 13 | Deep Brain Innvovations Deep brain stimulation technology | $393K | 87 mo ago | — | 2012 | Geoffrey Thrope CEO | — | — | — |
| 14 | DIRAmed Non-invasive meters to measure key body ingredients | $375K | 182 mo ago | 4 | 1999 | Robert Schlegel Chairman | — | 16 patents Calibration shutter components for spectroscopic medical diagnostic instruments | — |
| 15 | MemVu Online platform for mental health care coordination | $200K | 151 mo ago | 11 | 2008 | Bill Tymoszczuk CEO | — | 2 patents Cognitive training hardware/software for mental fitness applications | — |
| 16 | Ulevo Health Provider of wearable device to detect muscle spam | $150K | 39 mo ago | — | 2022 | Jack Karabees Co-Founder & CEO | — | — | — |
Top 12 Disease Self Management companies in Ohio
#1
Series D · Cleveland, Ohio · founded 2008 · 28 employees$89.2Mraised▾
Neuros Medical, a medical device company, is focused on developing neurostimulation therapies. Their device delivers high-frequency stimulation to sensory nerves in the peripheral nervous system to block chronic pain. The system consists of an electrode (also known as a lead) placed around a peripheral nerve and powered by a pacemaker-size generator. The company's platform technology, Nerve Block provides patients with the elimination of chronic pain and spasticity in a variety of applications including neuroma/residual limb pain with potential applications in cancer pain, diabetic neuropathy, cerebral palsy, multiple sclerosis, and stroke. The technology is patented and is awaiting FDA approval. It also offers the Neuros Altius System which consists of an implantable generator with an integrated rechargeable battery, cuff electrode, and external devices for performing neurostimulation procedures.
- Jul 2025Series D$56M
- Sep 2023Series B$20M
- Dec 2022Conventional Debt$8.2M
- Nov 2020Series B$38.5M
#2
Series B · Columbus, Ohio · founded 2021 · 20 employees$17.7Mraised▾
Mobile-based application of medication adherence management. Users can keep track of their medications and comply with the prescribed drug dosage regimen using the app. Also, it allows users to monitor their health status and store all the medical health data information in one place. Users can share medical data with healthcare providers for medical guidance.
- Aug 2025Series B$6M
- Jan 2024Series B$14M
- Aug 2022Series A$3.7M
- Oct 2021Seed—
#3
Seed · Kettering, Ohio · founded 2021 · 4 employees$2.6Mraised▾
Provider of wearable remote monitoring platform for cardiometabolic chronic diseases. The company offers Sunvida platform that measures biochemical parameters in a long-term wearable.
- Sep 2025Seed$264.5K
- Apr 2025Grant (prize money)$304.8K
- Mar 2025Grant (prize money)$304.8K
- Mar 2025Grant (prize money)$1.2M
#4
Series A · Cincinnati, Ohio · founded 2006 · 13 employees$22Mraised▾
Provider of therapy solutions for the treatment of musculoskeletal pain. It is offering cloud-based software, health informatics sensors, and inclusive equipment along with workouts and exercise libraries to users. It has an application called, The Access Strength, which is a smart machine that offers and tracks exercises, machine setup, or even how much weight to use.
- Nov 2024Series A$5M
- Feb 2023Series A$11M
- Jul 2017Series A$2.4M
- Aug 2015Seed$1.8M
#5
Seed · Delaware, Ohio · founded 2008 · 3 employees$4Mraised▾
Developer of a medical device for monitoring patients with phenylketonuria. The company has developed a portable Bluetooth-enabled disease management device that detects small molecules and biomarkers like phenylalanine and helps patients to maintain their diet.
- Jun 2025Seed—
- Jun 2024Seed—
- Mar 2022Seed$4M
#6
Funding Raised · Marysville, Ohio · founded 2001 · 18 employees$3.9Mraised▾
LifeBio provides a platform where seniors can share their experiences about any diseases or dementia. It also assists people facing health challenges or memory loss.
- Apr 2025Grant (prize money)$494.2K
- Sep 2024Grant (prize money)$432.3K
- Sep 2021Grant (prize money)$448.5K
- Aug 2020Grant (prize money)$2.5M
#7
Series D · Cleveland, Ohio · founded 2010 · 198 employees$173.9Mraised▾
Developer of a peripheral nerve stimulation therapy platform designed to treat severe pain. The company offers a non-narcotic, reversible, safe, effective, and affordable alternative to addictive opioid medications and invasive surgeries for acute and chronic pain management, enabling patients to get sustained and significant pain relief.
#8
Deadpooled · Cincinnati, Ohio · founded 2013 · 56 employees$15.5Mraised▾
Developer of wearable electronic wearable systems to sweat biomarkers. The company develops non-invasive, disposable, and electronic patches for remote, and quantitative medication monitoring through sweat human sweat. Also, it has applications ranging from opioid compliance to precision dosing of narrow therapeutic index drugs in oncology and organ transplant.
- Oct 2019Series B$1.9M
- Jun 2019Conventional Debt$621.9K
- Jul 2018Series B$6.6M
- Jul 2017Conventional Debt$861.5K
#9
Funding Raised · Cleveland, Ohio · founded 2003 · 15 employees$13.3Mraised▾
NeuroWave Systems develops neurodiagnostic and monitoring devices. The company's focus is on peri-operative neuromonitoring, seizure detection, and sleep architecture assessment. The NeuroSENSE Monitor is a bilateral brain monitor with EasyPrep electrodes. The company is ISO 13485 certified. The products are available in markets where the CE mark is recognized.
- Jul 2019Grant (prize money)$244.6K
- Sep 2014Grant (prize money)$1.5M
- Sep 2013Grant (prize money)$354.7K
- Jun 2010Grant (prize money)$499.8K
#10
Series A · Cleveland, Ohio · founded 2009 · 512 employees$7Mraised▾
Medication management and pharmacy care provider for complex medical needs. We specialize in comprehensive pharmacy care and medication management, helping individuals with chronic conditions live healthier lives at home. Our services include medication synchronization, adherence packaging, clinical support, and coordination with healthcare teams. We partner with healthcare organizations, including health plans, home health agencies, and hospitals, to improve patient outcomes, reduce readmissions, and lower the total cost of care. Our pharmacy care team, including licensed clinical pharmacists and pharmacy technicians, provides personalized support and medication counseling. We are licensed with the Boards of Pharmacy in all states and Washington, D.C. We offer online patient account access, prescription refills, and a dedicated helpline for medication-related questions. We focus on improving medication adherence, optimizing medication therapy, and enabling better patient health through our comprehensive services.
- Sep 2016Series A—
- Mar 2016Series A$7M
- Jan 2014Seed—
#11
Seed · Columbus, Ohio · founded 2020 · 4 employees$1.9Mraised▾
Developer of remote monitoring device for heart failures. It has developed a low-power radio frequency imaging sensor for monitoring heart failure and detecting fluid retention. It is a heart failure and heart health monitoring device. It has features for imaging sensors, radio frequency signals, data measurement, early detection of acute heart failure, and more.
- Feb 2021Seed$1.9M
#12
Seed · Columbus, Ohio · founded 2022$150Kraised▾
Provider of wearable device to detect muscle spam. The company offers a wearable device that detects muscle spasms and produces corrective stimulation as needed to immediately arrest the spasm and associated discomfort.
- Jun 2023Seed$150K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Disease Self Management coverage by sub-theme.
Regulatory-risk over time falling
Funding & growth over time
funding flat · growth flat
How research on Digital Health in Ohio is moving
A read on the academic research around Digital Health in Ohio — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 77 papers.
- The Ohio State University52
- The Ohio State University Wexner Medical Center13
- The Ohio State University at Lima6
- The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute5
- Ohio University5
- Cyberinfrastructure2
- Workforce2
- Curriculum2
- Leverage (statistics)2
- Workforce development2
- Health informatics11
- Health care10
- mHealth6
- Health administration6
- Informatics5
- Health informatics1→11