Best Disease Self Management Companies in Texas, United States
The 132 best Disease Self Management companies in Texas, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Happy Ring.
Our analysis of 50 Disease Self Management companies
$3.0b in tracked funding; 94% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Disease Self Management companies in Texas
| # | Company | Disclosed funding | Last round | Employees | Founder | Stage | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Happy Health Provider of at-home sleep disorder diagnosis and treatment | $60M | 45 mo ago | — | Caroline Chow Co-Founder & Registered Holistic Nutritionist | Series A | Top 10M | — | — |
| 2 | Happy Ring Smart ring for remote patient monitoring and personalised medical insights | $60M | 45 mo ago | 25 | Sean Rad Co-Founder | Series A | — | — | — |
| 3 | AllClear ID Provider of a platform consolidating and sharing patient medical records securely | $28M | 105 mo ago | 14 | — | Series B | Top 10M | 8 patents Secure mobile payment and authentication systems enabling cross-channel transactions. | — |
| 4 | Rey Online platform offering VR-based therapeutic sessions for mental health management | $26M | 58 mo ago | 43 | Deepak Gopalakrishnan Founder & CEO | Deadpooled | — | — | — |
| 5 | OxfordVR Provider of virtual devices for the treatment of psychological health | $19M | 76 mo ago | 35 | Daniel Freeman Co-Founder | Series A | Top 50M | — | — |
| 6 | Motif neurotech Developer of minimally invasive bioelectronics for mental health disorders | $19M | 28 mo ago | 7 | Jacob Robinson Co-Founder & CEO | Series A | Top 10M | 8 patents Closed-loop neural interfaces using implantable magnetoelectric stimulation and wireless monitoring | 1 partnership |
| 7 | Spark Biomedical Developer of wearable neurostimulation technology for drug-free opioid withdrawal treatment 53Patents top 23%Innovation top 26%Funding top 32%Moat top 38% All 10 signals ▾Patentstop 23% Innovationtop 26% Fundingtop 32% Moattop 38% Techtop 40% Growthtop 45% Talentbottom 49% Productbottom 48% Globalbottom 40% Marketbottom 29% Patents: 61 patents matched (strict assignee match) · 55 filings since 2022 vs 6 in 2017-21 Innovation: 61 patents (top 27% of patent-holders) · 55 filings since 2022 vs 6 in 2017-21 rank vs industry peers · Fliar Intelligence Index 53/100 | $16M | 10 mo ago | 18 18 → 27 (+50%) | Daniel Powell CEO | Series A | Top 10M | 61 patents Non‑invasive auricular neurostimulation devices for women's health therapies | 1 award |
| 8 | Fourth Frontier Provider of a connected wearable device for cardiac health monitoring | $15M | 59 mo ago | 48 48 → 76 (+58%) | Manav Bhushan Co-Founder & Co-CEO | Series B | Top 5M | — | 5 job openings |
| 9 | Inito Provider of test devices to track fertility hormones at home 64Tech top 22%Growth top 23%Funding top 32%News top 38% All 13 signals ▾Techtop 22% Growthtop 23% Fundingtop 32% Newstop 38% Talenttop 38% Moattop 41% Innovationtop 46% Patentstop 46% Producttop 46% Marketbottom 46% Globalbottom 46% Fin. healthbottom 46% Customersbottom 36% Tech: 54 technologies across 6/8 capability areas · Cloud: Amazon Web Services, Cloudflare Growth: Headcount 108 → 175 (+62%) across vintages · Web rank 5,000,000 → 1,000,000 YoY rank vs industry peers · Fliar Intelligence Index 64/100 | $15M | 6 mo ago | 175 175 → 253 (+45%) | Varun Akur venkatesan Co-Founder & CTO | Series B | Top 1M | 3 patents Optical biosensing platforms for hormone assays and microbial load measurement | — |
| 10 | HeartSciences Provider of a screening device for the early detection of cardiac dysfunction | $8M | 31 mo ago | 12 12 → 23 (+92%) | Mark Hilz CEO | Public | Top 5M | 3 patents Non‑invasive ECG algorithms for deriving echocardiographic measurements and quantitative cardiac assessment | 3 launchs · 1 partnership |
| 11 | Dele Provider of AI-based software solution and device for the fall detection for elderly people | $7M | 65 mo ago | 17 | — | Series A | — | — | — |
| 12 | LVL Technologies Provider of wearable sensor to monitor hydration levels | $7M | 106 mo ago | 11 | — | Deadpooled | — | 3 patents Residential low-voltage electrical fixtures: lamps, dimmer switches, outdoor outlet covers. | — |
| 13 | Noninvasix Developer of a fetal blood oxygenation monitoring device | $6M | 65 mo ago | 3 | David Giarracco Chief Executive Officer | Seed | — | 21 patents Patents concentrated in health & consumer products | — |
| 14 | UnaliWear Medical alert watch with fall detection for independent living | $6M | 72 mo ago | 19 | Jean Anne Booth CEO | Series A | Top 5M | 14 patents Patents concentrated in computing, sensing & instrumentation | — |
| 15 | Berkshire Biomedical Provider of cloud-based smart device for drug dispensing 22Moat top 32%Patents top 36%Innovation top 37%Talent top 38% All 8 signals ▾Moattop 32% Patentstop 36% Innovationtop 37% Talenttop 38% Fundingtop 41% Globalbottom 35% Newsbottom 27% Marketbottom 10% Moat: Editorial + unicorn rating 5/10 · IP moat: 45 patents Patents: 45 patents matched (strict assignee match) · 19 filings since 2022 vs 26 in 2017-21 rank vs industry peers · Fliar Intelligence Index 22/100 | $6M | 12 mo ago | 4 | Tommy Rouse Co-Founder & Chairman | Seed | — | 45 patents Secure, automated oral medication dispensing and refill management systems for patient adherence | — |
| 16 | Healium Provider of VR-based meditation app for stress and sleep management | $5M | 30 mo ago | 20 | — | Seed | Top 5M | — | — |
| 17 | Rosy Provider of a mobile-based app for the women to ask questions related to sexual health | $4M | 55 mo ago | 6 | Lyndsey Harper Founder & CEO | Seed | Top 5M | — | — |
| 18 | Throne Provider of gut health and hydration tracking device 45Growth top 28%Moat top 38%Talent top 38%Patents top 41% All 10 signals ▾Growthtop 28% Moattop 38% Talenttop 38% Patentstop 41% Innovationtop 42% Techtop 48% Productbottom 45% Fundingbottom 44% Globalbottom 31% Marketbottom 28% Growth: Web rank 10,000,000 → 5,000,000 YoY · Fresh capital in last 24 mo Moat: Editorial + unicorn rating 4/10 · IP moat: 8 patents rank vs industry peers · Fliar Intelligence Index 45/100 | $4M | 12 mo ago | — | Timothy Blumberg Co-Founder & CTO | Seed | Top 5M | 8 patents Sanitary fixture accessories, waste emission monitoring, and public bathroom management solutions | 1 launch · 1 award |
| 19 | knowRX Digital medication management system for pharmacists, providers, and caregivers | $4M | 37 mo ago | 9 | David Franklin Co-Founder & CEO | Series A | — | — | — |
| 20 | Socrates Health Non-invasive blood glucose monitoring sensor | $4M | 120 mo ago | 3 | — | Seed | — | — | — |
| 21 | MedHab Remote patient monitoring and therapeutic devices for improved health and performance | $2M | 95 mo ago | 8 | — | Seed | — | 33 patents Wearable health monitoring devices for fall detection, gait analysis, and activity tracking | — |
| 22 | MR3Health Provider of monitoring services to health insurers for diabetic neuropathy patients | $1M | 47 mo ago | 10 | — | Public | — | — | — |
| 23 | Advanced Maternity Innovations Medical technologies for pregnancy monitoring & management | $1M | 168 mo ago | 4 | Jack McCrary CEO & MD | Funding Raised | — | — | — |
| 24 | ASD.ai AI-based mobile app for children with autism | $1M | 56 mo ago | 7 | Blake Rutherford Co-Founder | Seed | — | 34 patents Patents concentrated in computing, sensing & instrumentation | — |
| 25 | Wulou Labs Domain sales and pricing services with expert support | $825K | 133 mo ago | — | Rob Kulis Co-Founder & CEO | Deadpooled | — | — | — |
| 26 | 1 True Health Provider of solutions for patients and professionals to manage medical data | $800K | 28 mo ago | — | Shawn Smith CEO | Seed | — | — | — |
| 27 | Line Health D2C medication adherence app | $784K | 106 mo ago | 9 | Diogo Ortega Co-Founder & CEO | Deadpooled | — | — | — |
| 28 | Health Behavior Solutions Digital therapeutics for emotional well-being through evidence-based cognitive behavioral therapy | $760K | 32 mo ago | — | Jay Brown Co-Founder & CMO | Funding Raised | — | — | — |
| 29 | Vironix AI Provider of remote patient monitoring platform, devices, and clinician support | $756K | 20 mo ago | 2 | Sriram Ramanathan Founder and Advisor | Seed | Top 5M | — | 1 award |
| 30 | Nerveli A digital health platform providing personalized approach to pain management and recovery | $540K | 9 mo ago | — | Leon Jacobson CEO & Co-Founder | Seed | — | — | — |
| 31 | Anatomotion Developer of a wearable technology solution for dental care | $505K | 119 mo ago | 3 | Shane Matt Founder & CEO | Seed | — | — | — |
| 32 | Mediphant Developer of an AI-powered platform for personal health data management | $330K | 10 mo ago | — | Venu Nair Co-Founder & CTO | Seed | — | — | 1 job opening · 5 launchs |
| 33 | Bairitone Health AI-based anatomy assessment at home during natural sleep | $300K | 32 mo ago | 4 | Meagan Pitcher Co-Founder & CEO | Seed | Top 50M | — | — |
| 34 | Vytalyx Decentralized data exchange platform for the healthcare industry | $280K | 101 mo ago | 2 | David Granzotti Co-Founder & CEO | Funding Raised | — | — | — |
| 35 | EllieGrid Provider of hardware and software solutions for medication management | $150K | 96 mo ago | 4 | — | Seed | Top 10M | — | — |
| 36 | Simple Strips Provider of glucose strips & mobile app for body glucose monitoring | $125K | 75 mo ago | — | Salil Pathare Co-Founder & CTO | Deadpooled | — | — | — |
| 37 | Omaiven AI and cloud-based practice management tool for providers | $120K | 35 mo ago | — | Jerold McDonald Co-Founder + CEO | Seed | — | — | — |
| 38 | Briocare Provider of app for home care management | $100K | 68 mo ago | 11 | Shaun Mitra Founder | Seed | — | — | — |
Top 12 Disease Self Management companies in Texas
#1
Series B · Houston, Texas · founded 2012 · 175 employees$15Mraised▾
Provider of test devices to track fertility hormones at home. The monitoring system works by measuring hormones such as Estrogen, LH, PdG and FSH in the urine sample to track fertility and confirm ovulation. The device is integrated with an app to provide a full picture of cycles with results.
- Dec 2025Series B$29M
- Sep 2023Series A$6M
- Nov 2022Seed—
- Aug 2020Angel$21.5K
#2
Series A · Houston, Texas · founded 2018 · 18 employees$16.2Mraised▾
Developer of wearable neurostimulation technology for drug-free opioid withdrawal treatment. The company provides non-invasive bioelectric medicine designed to meet critical needs. Their current FDA-cleared neurostimulation solution is for opioid withdrawal. The technology is also evolving into neurological health, hemostasis, and pediatrics.
- Aug 2025Grant (prize money)—
- Apr 2025Series A$15M
- Jun 2024Grant (prize money)$318.9K
- May 2023Series A$16.2M
#3
Seed · Dallas, Texas · founded 2016 · 4 employees$5.8Mraised▾
Berkshire Biomedical provides cloud-based smart devices for drug dispensing. The device provides notifications to take prescribed drugs at different intervals. It also has personalized biometric authorization that controls fingerprint and dental recognition, and a cloud-based DBMS for data storage.
- May 2025Grant (prize money)$326.4K
- Aug 2022Grant (prize money)$2M
- Aug 2022Grant (prize money)$2.2M
- Oct 2021Seed$2.8M
#4
Seed · Austin, Texas · founded 2023$4Mraised▾
Provider of gut health and hydration tracking device. The company focuses on developing health solutions, particularly gut health and hydration monitoring through a device that attaches to the toilet bowl, offering insights into hydration levels and gut health.
- May 2025Seed$4M
#5
Seed · Dallas, Texas · founded 2022$540Kraised▾
A digital health platform providing personalized approach to pain management and recovery. The company provides users with an empathetic and interactive pain recovery assistant by combining proven medical science, gamified Cognitive Behavioral Therapy, and machine learning to manage chronic pain through evidence-based and personalized recommendations.
- Sep 2025Seed$540K
#6
Seed · Dallas, Texas · founded 2025$330Kraised▾
Developer of an AI-powered platform for personal health data management. The platform enables users to consolidate and interpret health information from various sources. It provides personalized recommendations and helps users track their health. The platform also assists in understanding medical reports and preparing for doctor visits. It aims to provide accessible health insights.
- Aug 2025Seed$100K
- Jul 2025Seed$230K
#7
Series A · Houston, Texas · founded 2022 · 7 employees$18.8Mraised▾
Developer of minimally invasive bioelectronics for mental health disorders. It offers a miniature brain pacemaker that stimulate the brain to restore healthy circuit activity and treat mental health disorders like treatment resistant depression.
- Jan 2024Series A$18.8M
#8
Series A · Austin, Texas · founded 2019$60Mraised▾
Provider of at-home sleep disorder diagnosis and treatment. It offers an FDA-cleared sleep test device and a care team of board-certified sleep physicians. The service includes personalized treatment plans, encompassing various options such as custom-fit devices and CPAP therapy. Patients receive ongoing monitoring and support from their care team. The platform aims to provide convenient and accessible sleep health solutions.
- Aug 2022Series A$60M
#9
Series A · Austin, Texas · founded 2019 · 25 employees$60Mraised▾
Smart ring for remote patient monitoring and personalised medical insights. It uses biometric sensors and AI technology to deliver personalized medical insights to medical professionals. It is also used for decentralized clinical trials with remote patient onboarding, streaming of patient biomarkers and integration into eClinical platforms and EHR.
- Aug 2022Series A$60M
#10
Seed · Austin, Texas · founded 2020 · 2 employees$756Kraised▾
Provider of remote patient monitoring platform, devices, and clinician support. The platform supports virtual care management services, including remote patient and therapeutic monitoring. It facilitates chronic and principal care management. The platform offers condition-specific care plans and health data tracking. It also provides automated claims tracking and audit reports. The system uses algorithms to identify patients at risk.
- Oct 2024Seed$1.8M
- May 2023Seed$1.1M
- Aug 2022Seed$276K
- Nov 2020Seed$25K
#11
Public · Austin, Texas · founded 2007 · 12 employees$8.2Mraised▾
Provider of a screening device for the early detection of cardiac dysfunction. The company has Continuous Wavelet Transform signal processing technology for developing MyoVista cardiac testing device to detect abnormalities of heart function. It provides doctors with a visual description of a cardiac cycle’s energy distribution.
- Nov 2023Post IPO$1.6M
- Sep 2023Post IPO$1M
- Feb 2021Conventional Debt$1.1M
- Nov 2019Series A$138K
#12
Seed · Austin, Texas · founded 2024$30Kraised▾
Developer of wearable device for continuous real-time hormone data monitoring. The device uses an aptamer-based sensing platform to detect hormonal changes. It aims to provide individuals with access to continuous hormone insights. The device merges biotechnology with wearable design to deliver accurate data.
- Nov 2025Seed$30K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Disease Self Management coverage by sub-theme.
Regulatory-risk over time falling
Funding & growth over time
funding flat · growth flat
How research on Digital Health in Texas is moving
A read on the academic research around Digital Health in Texas — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 343 papers.
UT Health Houston, UT Austin, and Texas A&M lead Texas digital-health research—focusing on EHR systems, AI, and mobile health—with a cautiously contested tone (concern-dominant, mean stance 0.18).
- The University of Texas Health Science Center at Houston66
- The University of Texas at Austin56
- Texas A&M University39
- The University of Texas Southwestern Medical Center25
- The University of Texas Health Science Center at San Antonio23
- Health informatics1→7
- Health care1→41
- Health informatics4→29
- Informatics1→16
- Psychological intervention1→12
- Health administration4→9
- Health informatics17→43
- Health care7→27
- Public health6→21
- Nursing research4→13
- Health administration8→16
Common questions
Sweetie watches where the money and the users are piling in. She covers sector wealth and momentum — the install curves and revenue pools that show which corners of the market are quietly on fire.