Best HealthTech Companies in Cleveland, United States
The 77 best HealthTech companies in Cleveland, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: SPR Therapeutics.
Our analysis of 305 HealthTech companies
$32.1b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best HealthTech companies in Cleveland
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | SPR Therapeutics Peripheral nerve stimulation therapy for treating pain | $174M | 28 mo ago | 198 | 2010 | Maria E Bennett Founder & CEO | — | 220 patents Implantable neurostimulation systems for chronic pain and back pain relief | — |
| 2 | Within3 Provider of an online collaboration solutions | $103M | 68 mo ago | 196 196 → 120 (-39%) · sector median -2% | 2006 | Lance Hill Founder & CEO | WordPressApple iCloud MailMySQL+24 | 13 patents Integrating and analyzing biomedical datasets with linked databases and image/social network analytics | — |
| 3 | Neuros Medical Neurostimulation therapy for chronic neuropathic pain 40Funding top 18%Moat top 31%Growth top 48%Tech top 49% All 8 signals ▾Fundingtop 18% Moattop 31% Growthtop 48% Techtop 49% Talentbottom 49% Globalbottom 39% Marketbottom 31% Newsbottom 22% Funding: Raised $89.2M across 14 rounds · 14 rounds over 17 yrs (0.8/yr) Moat: Editorial + unicorn rating 8/10 · Soonicorn rank vs industry peers · Fliar Intelligence Index 40/100 | $89M | 11 mo ago | 28 28 → 53 (+89%) · sector median -2% | 2008 | David Veino CEO | WordPressSentryApple iCloud Mail+24 | — | — |
| 4 | PartsSource Healthcare equipment parts, repair, and service solutions provider | $50M | 214 mo ago | 284 284 → 584 (+106%) · sector median -2% | 2001 | Ray Dalton Founder | Cart FunctionalityBloomreachApple iCloud Mail+34 | 3 patents Online platforms facilitating sourcing of replacement parts for equipment maintenance | 4 partnerships · 2 awards |
| 5 | Axuall Offers digital credentialing services for healthcare providers | $41M | 35 mo ago | 87 87 → 87 (+0%) · sector median -2% | 2018 | Charlie Lougheed Co-Founder & CEO | WordPressApple iCloud MailGoogle Workspace+29 | 5 patents Digital credential verification and management for secure identity authentication | — |
| 6 | OnShift SaaS based staff scheduling and shift management software for the healthcare industry | $34M | 48 mo ago | 191 191 → 102 (-47%) · sector median -2% | 2008 | — | HubSpot CMS HubSentrySalesforce+20 | — | — |
| 7 | MediView Digital medical image management tool for providers | $29M | 6 mo ago | 6 | 2017 | Adam Rakestraw Co-Founder | WordPressMySQLPHP+31 | 71 patents AR/VR imaging fusion for real-time cardiovascular intervention guidance and device deployment | 1 job opening · 1 partnership |
| 8 | COMS Interactive Post care solution to avoid readmissions of patients | $27M | 127 mo ago | 60 | 2009 | — | — | — | — |
| 9 | Bravo Wellness Wellness incentive programs provider | $22M | 142 mo ago | 217 | 2008 | — | RubySalesforceRuby on Rails+9 | — | — |
| 10 | DATATRAK Cloud-based clinical trial data management solutions for efficient research | $21M | 94 mo ago | 50 | 1991 | Jim Bob Ward President & CEO | — | 8 patents Enterprise data integration and unified data management platforms | — |
| 11 | GL Neurotech Developer of bioinstrumentation products for physiological monitoring and therapy | $18M | 17 mo ago | 15 15 → 21 (+40%) · sector median -2% | 2010 | Robert Schmidt Chairman and CEO | — | — | — |
| 12 | Explorys Provides a cloud computing platform for the healthcare industry. | $15M | 181 mo ago | 144 | 2009 | Charlie Lougheed Co-Founder | — | — | — |
| 13 | explorys.net Cloud-computing platform that allows healthcare systems to aggregate, analyze, manage, and research data | $14M | 181 mo ago | 144 | 2009 | — | — | — | — |
| 14 | Complion Software solutions for clinical trial regulatory documentation. | $14M | 73 mo ago | 33 | 2012 | — | — | — | — |
| 15 | NeuroWave Systems Neurodiagnostic device and accessories | $13M | 83 mo ago | 15 | 2003 | — | Apache HTTP ServerStatcounterGoogle Analytics+2 | — | — |
| 16 | Graici Provider of AI-powered solutions for healthcare enrollment and engagement | $8M | 14 mo ago | — | 2021 | Stephen McHale CEO | HubSpot CMS HubAmazon Web ServicesHubSpot+15 | — | 1 award |
| 17 | ExactCare Pharmacy Medication management and pharmacy care provider for complex medical needs | $7M | 117 mo ago | 512 512 → 445 (-13%) · sector median -2% | 2009 | Dale Wollschleger Founder & CEO | WordPressApple iCloud MailMySQL+22 | — | 1 job opening |
| 18 | GenomOncology Developer of precision medicine by transforming genomic data into actionable information | $6M | 74 mo ago | 56 56 → 53 (-5%) · sector median -2% | 2012 | — | — | 3 patents Computational analysis of genomic variants using discrete data structures for precision oncology | 1 job opening |
| 19 | OpsiClear Developer of photorealistic 3D digital twins of biological specimens | $3M | 12 mo ago | — | 2021 | Michael Jenkins Co-Founder | — | — | — |
| 20 | TPA Stream Benefits administration solution streamlining claims, invoicing, and communications for administrators | $3M | 20 mo ago | 28 | 2014 | Eric Sukalac Co-Founder and CPO | — | — | 1 partnership |
| 21 | Zivian Healthcare SaaS platform facilitating compliant collaborations between nurse practitioners and physicians | $3M | 34 mo ago | 8 | 2009 | Rafid Fadul Md Co-Founder | WordPressMySQLRedis+27 | — | — |
| 22 | Q Centrix Clinical data solutions optimizing healthcare performance, research, and patient outcomes | $3M | 90 mo ago | 1,088 1,088 → 837 (-23%) · sector median -2% | 2007 | — | WordPress Block EditorWordPressApple iCloud Mail+21 | 264 patents Dental impression and anesthesia devices; blind and expandable fastener technologies. | — |
| 23 | Malachite Innovations Developer cannabis-derived novel treatments for gastrointestinal diseases | $2M | 38 mo ago | 40 | 2007 | Michael Cavanaugh CEO | — | — | — |
| 24 | Healthcare Navigation Solutions Provider of healthcare navigation solutions for cancer care | $2M | 27 mo ago | — | 2022 | Chip Long President & CEO | — | — | — |
| 25 | Sequentia Care coordination platform for post-acute and extended care providers | $1M | 119 mo ago | 4 | 2011 | Gennaro Luce CEO | — | 2 patents Healthcare IT platforms for extended care planning and management workflows | — |
| 26 | My One Medical Source Platform connecting patients and providers for booking diagnostic and clinical testing | $1M | 14 mo ago | 9 | 2020 | Brad Seybert Founder & President | TypeScriptGoogle MapsCoreUI+15 | — | — |
| 27 | MedaSync AI-based software for data intelligence and workflow automation | $550K | 9 mo ago | 5 | 2016 | Ryan Edgerly CEO | — | — | 1 partnership |
| 28 | Deep Brain Innvovations Deep brain stimulation technology | $393K | 84 mo ago | — | 2012 | Geoffrey Thrope CEO | — | — | — |
| 29 | iRx Reminder A smartphone-based clinical trial management system | $250K | 105 mo ago | — | 2009 | — | — | — | — |
| 30 | MemVu Online platform for mental health care coordination | $200K | 149 mo ago | 11 | 2008 | Bill Tymoszczuk CEO | — | 2 patents Cognitive training hardware/software for mental fitness applications | — |
| 31 | SpiroSano SaaS based platform to track respiratory conditions of patients | $100K | 138 mo ago | — | 2014 | Radu Iancu CEO & Co-Founder | — | — | — |
Top 12 HealthTech companies in Cleveland
#1
Series A · Cleveland, Ohio · founded 2017 · 6 employees$29.4Mraised▾
Digital medical image management tool for providers. The company has developed software like MediView XR30, MediView XR50, and MediView XR90. It has features for augmented reality visualization, remote collaboration, clinical image analysis, and democratizing and informing healthcare delivery.
- Nov 2025Series A$24M
- Oct 2025Series A$24M
- Dec 2024Series A$14M
- May 2023Series A$15M
#2
Series D · Cleveland, Ohio · founded 2008 · 28 employees$89.2Mraised▾
Neuros Medical, a medical device company, is focused on developing neurostimulation therapies. Their device delivers high-frequency stimulation to sensory nerves in the peripheral nervous system to block chronic pain. The system consists of an electrode (also known as a lead) placed around a peripheral nerve and powered by a pacemaker-size generator. The company's platform technology, Nerve Block provides patients with the elimination of chronic pain and spasticity in a variety of applications including neuroma/residual limb pain with potential applications in cancer pain, diabetic neuropathy, cerebral palsy, multiple sclerosis, and stroke. The technology is patented and is awaiting FDA approval. It also offers the Neuros Altius System which consists of an implantable generator with an integrated rechargeable battery, cuff electrode, and external devices for performing neurostimulation procedures.
- Jul 2025Series D$56M
- Sep 2023Series B$20M
- Dec 2022Conventional Debt$8.2M
- Nov 2020Series B$38.5M
#3
Funding Raised · Cleveland, Ohio · founded 2010 · 15 employees$17.9Mraised▾
Developer of bioinstrumentation products for physiological monitoring and therapy. The products include physiological monitors and patient-centered diagnostic and therapy systems integrated with wireless, remote, and web-based applications. The companys offerings support research and education, focusing on movement disorders like parkinsons disease, telemedicine, and in-home health monitoring. Manufacturing, distribution, and export of research systems and medical devices are also core business activities.
- Jan 2025Grant (prize money)$1.7M
- Sep 2023Grant (prize money)$289.5K
- Sep 2018Grant (prize money)$1.7M
- Jul 2018Grant (prize money)$224.7K
#4
Series A · Cleveland, Ohio · founded 2021$7.5Mraised▾
Provider of AI-powered solutions for healthcare enrollment and engagement. This system automates administrative tasks, improves workflows, and facilitates real-time communication between patients, providers, and health plan staff. It offers personalized assistance to members and providers, streamlining processes related to Medicaid eligibility and enrollment, and addressing social determinants of health. The technology is designed to improve access to essential resources and enhance overall efficiency within healthcare systems. It leverages advanced language models and other technologies for optimal performance and results.
- Apr 2025Series A$7.5M
#5
Funding Raised · Cleveland, Ohio · founded 2021$3.4Mraised▾
Developer of photorealistic 3D digital twins of biological specimens. This technology creates in silico clones of biological samples, enabling enhanced medical knowledge and surgical precision through spatial AI. The digital twins offer detailed, accurate representations for analysis and planning, supporting advancements in various medical fields. The process leverages advanced imaging and AI techniques to generate highly realistic models.
- May 2025Grant (prize money)$2M
- Apr 2022Grant (prize money)$1.5M
#6
Series D · Cleveland, Ohio · founded 2010 · 198 employees$173.9Mraised▾
Developer of a peripheral nerve stimulation therapy platform designed to treat severe pain. The company offers a non-narcotic, reversible, safe, effective, and affordable alternative to addictive opioid medications and invasive surgeries for acute and chronic pain management, enabling patients to get sustained and significant pain relief.
#7
Seed · Cleveland, Ohio · founded 2016 · 5 employees$550Kraised▾
AI-based data intelligence and workflow automation software. Solutions offered by the company include cost analytics, case management, and business intelligence. Cost analytics assists in the identification of high-cost medications and equipment. Case management aids in the management of patient stay, monitoring clinical changes, and service costs, and transitions.
- Aug 2025Seed—
- Feb 2024Seed$1.6M
- Jul 2018Seed$550K
- May 2018Grant (prize money)$25K
#8
Series A · Cleveland, Ohio · founded 2020 · 9 employees$1.1Mraised▾
Platform connecting patients and providers for booking diagnostic and clinical testing. The company enables patients to book different medical services like testing, teleconsultation, and more. It can also be used by professionals to order specimen collection, laboratory testing, and more.
- Mar 2025Series A$4.6M
- Apr 2022Seed$1.1M
#9
Seed · Cleveland, Ohio · founded 2014 · 28 employees$3.4Mraised▾
Benefits administration solution streamlining claims, invoicing, and communications for administrators. This company offers a benefits admin solution designed to connect systems, transform data, and unlock revenue for Third Party Administrators, Health Insurance Brokers, Application Developers, HSA Providers, and Benefits Startups. The platform provides consolidated invoicing, communications tools, and claims harvesting capabilities. It helps automate administration processes, improve benefits, and save time and money. The company's solutions include a Software Development Kit, aiming to empower better healthcare outcomes for employers and their employees. It is a technology company committed to innovation in the insurance sector, offering a web-based platform that supports various administrative needs. The platform integrates with existing systems to streamline workflows and enhance client experience. Key features include secure data collection, automated communications, and efficient billing processes. The company focuses on making benefits easier through its cloud-based platform.
#10
Series B · Cleveland, Ohio · founded 2018 · 87 employees$41Mraised▾
Auxall offers digital credentialing services for health providers. The platform is a global identity network that enables people to collect and manage their verified credentials from authorized issuers and share them with employers.
- Jul 2023Series B$7M
- May 2023Series B$20M
- Jul 2021Series A$10.4M
- Sep 2019Seed$3M
#11
Series E · Cleveland, Ohio · founded 2008 · 191 employees$33.6Mraised▾
SaaS based staff scheduling and shift management software for the healthcare industry. It predicts and prevents overtime and understaffing while dramatically reducing time spent on scheduling and managing open shifts. Fully integrated with time keeping, HR, clinical and payroll systems, provides a unified view into staffing levels and labor costs across buildings.
- Jun 2022Series E—
- Oct 2018Series D—
- Apr 2016Series D$18.1M
- Feb 2014Series C$7.5M
#12
Series C · Cleveland, Ohio · founded 2006 · 196 employees$102.6Mraised▾
Within3 offers a digital communication platform for the health and life sciences markets. The solution helps healthcare professionals with their networking needs, have real-time meetings or web conferences, and provides an online discussion platform where professionals can discuss at a convenient time.
- Sep 2020Series C$100M
- Jul 2012Series A$2.6M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of HealthTech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health in Cleveland is moving
A read on the academic research around Digital Health in Cleveland — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 58 papers.
- Cleveland Clinic41
- Cleveland Clinic Lerner College of Medicine8
- Louis Stokes Cleveland VA Medical Center7
- University Hospitals of Cleveland4
- Cleveland State University2
- Health care1→3
- Health care1→6
- Health informatics1→3
- Psychological intervention1→4
- Informatics1→3
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.