Best HealthTech Companies in South Carolina, United States
The 123 best HealthTech companies in South Carolina, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: AccessOne.
Our analysis of 305 HealthTech companies
$32.1b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best HealthTech companies in South Carolina
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | AccessOne Patient healthcare payment processing solutions for businesses | $375M | 79 mo ago | 118 118 → 135 (+14%) | Russell Salton Founder & Owner | WordPressMySQLMariaDB+28 | Top 5M | — | — |
| 2 | Hope Health Online platform for booking doctor teleconsultation | $225M | 10 mo ago | 492 492 → 378 (-23%) | — | WordPressApple iCloud MailMySQL+33 | Top 5M | — | 1 award |
| 3 | Glytec Systems Cloud-based Insulin and glucose dosing software solution | $44M | 61 mo ago | 124 124 → 83 (-33%) | Bob Leonard Ex-CEO & President | — | — | — | — |
| 4 | ChartSpan Mobile app for Patient health records | $37M | 84 mo ago | 171 171 → 235 (+37%) | — | WordPressApple iCloud MailGoogle Workspace+28 | Top 5M | — | — |
| 5 | Verge Health SaaS based solution to manage hospital processes, personnel and asses physician performance | $16M | 94 mo ago | 140 | — | WordPressMySQLPHP+20 | Top 50M | — | — |
| 6 | Sync.MD App for personal health record management | $14M | 56 mo ago | 22 | Jacob Grinberg Co-Founder | ZohoFacebook LoginTailwind CSS+11 | Top 10M | — | 1 launch |
| 7 | Rymedi Cloud-based precision health platform enabling secure data sharing and patient-centered solutions | $9M | 31 mo ago | 26 | Jason Cross Co-Founder & Chief Strategy Officer | WordPressMySQLPHP+19 | Top 50M | 8 patents Secure health data exchange via blockchain, cryptographic ciphers, and zero‑knowledge compliance proofs | — |
| 8 | PaceMate Provider of cloud-based cardiac health remote monitoring platform | $8M | 34 mo ago | 109 | — | HubSpot CMS HubApple iCloud MailSalesforce+23 | Top 5M | — | — |
| 9 | ThoroughCare Care coordination software and clinical guidance to optimize patient care management | $8M | 1 mo ago | 10 | — | HubSpot CMS HubApple iCloud MailGoogle Workspace+22 | Top 5M | — | 1 partnership |
| 10 | Rainwalk Technology Online platform offering insurance plans for pets | $7M | 25 mo ago | 9 | Tong Wu Co-Founder | WordPressMySQLPHP+30 | Top 10M | — | — |
| 11 | Blinktbi Innovating neurological disease management with non-invasive blink reflex technology | $7M | 35 mo ago | 8 | Ryan Fiorini Co-Founder & COO | — | — | 14 patents Wearable ocular blink detection and monitoring for neurological and headache disorder diagnostics | — |
| 12 | Circuit Mobile-based application providing fitness & wellness training solutions | $5M | 85 mo ago | 81 | — | WordPress Block EditorWordPressApple iCloud Mail+21 | Top 50M | 3 patents Automated circuit design, data management, and functional verification platforms | — |
| 13 | PharmRight Corporation Medication dispenser and adherence monitoring solution | $4M | 106 mo ago | 3 | — | WebflowZohoVimeo+12 | Top 10M | 7 patents Pharmaceutical dose dispensing devices and related storage/slot mechanisms | — |
| 14 | Hank Cognitive engine providing medical coding automation solution | $3M | 39 mo ago | 11 11 → 14 (+27%) | Sam Hartzog Co-Founder and Chief Data Officer | WordPressMySQLPHP+18 | Top 50M | — | — |
| 15 | Encite Healthcare software solutions provider specializing in EHR, PM, and RCM services | $3M | 202 mo ago | 8 | — | — | — | 161 patents Micro‑scale MEMS fluidic and pressure devices for respiratory and gas‑handling applications | — |
| 16 | Equiscript Data-driven solutions for 340B program administration, referral capture, and clinical needs | $2M | 30 mo ago | 76 | — | HubSpot CMS HubSalesforceAmazon Web Services+14 | Top 50M | — | — |
| 17 | Formly.ai AI and cloud-based medical device management tool | $2M | 9 mo ago | 4 | — | Webflow EcommerceWebflowZoho+12 | Top 10M | — | — |
| 18 | Karias Provider of healthcare plans and technology platform for employers and brokers | $2M | 3 mo ago | — | Nicole Semeraro Founder & CEO | WebflowGSAPcore-js+15 | Top 50M | — | — |
| 19 | SPOTLYFE Cloud-based workplace wellness management tool | $1M | 52 mo ago | 11 | — | — | — | — | — |
| 20 | RingMD Provider of healthcare teleconsultation marketplace for patients and providers | $500K | 60 mo ago | 10 | — | Node.jsVue.jsNuxt.js+11 | Top 50M | — | — |
| 21 | Recovr Creates therapy tools that enhance physical rehabilitation in skilled nursing facilities | $425K | 70 mo ago | 3 | — | — | — | — | — |
| 22 | Nursenav Oncology Patient navigation software streamlining oncology care with digital onboarding and workflow automation | $373K | 198 mo ago | 5 | — | — | — | — | — |
| 23 | ItRunsInMyFamily Mobile-based application to analyze risk for hereditary cancer | $286K | 81 mo ago | — | Brandon M Welch Founder and Creator | — | — | — | — |
| 24 | Vetlexicon Provider of educational resources for veterinary professionals to treat, learn, and communicate | $202K | 104 mo ago | 23 | — | Cart FunctionalityWooCommerceWordPress+42 | Top 1M | — | — |
| 25 | Avallano Developer of clinical research platform for clinical trial patient engagement | $200K | 64 mo ago | 7 | Paul Maggiora Co-Founder & CEO | — | — | — | — |
| 26 | CareIT Web based virtual doctor's office and medical services marketplace | $100K | 130 mo ago | 10 | — | Apache HTTP Server | Top 50M | — | — |
| 27 | HealthCard4Free Discount health card offering savings on dental, vision, hearing, and prescriptions | $100K | — | 2 | Charles B Eisenson CEO & President | WordPressMySQLPHP+11 | Top 50M | — | — |
| 28 | Incora Health Platform offering a smart earring wearable device tracking menstrual cycles | $25K | 25 mo ago | — | Lindsey Calcutt CEO and Co-Founder | Cart FunctionalityShopifyTailwind CSS+18 | Top 10M | — | — |
| 29 | Rhinogram Provider of patient engagement platform for professionals | $14K | 47 mo ago | 26 26 → 19 (-27%) | — | Apple iCloud MailGoogle WorkspaceFacebook Login+10 | Top 5M | 20 patents Secure messaging integration with automated consent and autoreply management for telecom communications | — |
Top 12 HealthTech companies in South Carolina
#1
Funding Raised · Florence, South Carolina · founded 1991 · 492 employees$225Mraised▾
Online platform for booking doctor teleconsultation
- Aug 2025Grant (prize money)$4.3M
- Jul 2025Grant (prize money)$589K
- 2025Grant (prize money)$3.4M
- Apr 2025Grant (prize money)—
#2
Series A · Spartanburg, South Carolina · founded 2013 · 10 employees$8Mraised▾
Care coordination software and clinical guidance to optimize patient care management. The company empowers healthcare providers with purpose-built software solutions and expert clinical guidance to enhance patient care management. It offers a comprehensive platform designed to streamline care coordination, improve patient engagement, and maximize efficiency. The software supports various care models, including chronic care management, remote patient monitoring, and behavioral health integration. It provides tools for advance care planning, AI analytics, and annual wellness visits. The platform is NCQA Prevalidated, ensuring alignment with evidence-based quality standards and HIPAA compliance. The company supports accountable care organizations, health plans, home health agencies, pharmacies, and physician groups, offering integration and interoperability solutions, clinical advisory services, and training. It leverages AI to analyze patient calls, automate care plans, and enhance engagement through secure messaging and educational resources. The goal is to enable integrated, coordinated care, improve patient outcomes, and drive value-based reimbursement in the healthcare ecosystem.
- Oct 2025Series A$3M
- Sep 2024Series A$5M
- May 2022Series A$3M
- Feb 2014Seed—
#3
Seed · Okatie, South Carolina · founded 2023$1.5Mraised▾
Provider of healthcare plans and technology platform for employers and brokers. The platform offers tools for employees to find affordable care options. It also provides brokers with health plans designed to lower costs and reduce administrative tasks. The platform aims to deliver a transparent health plan strategy.
- Feb 2026Seed$1.5M
#4
Seed · Mount Pleasant, South Carolina · founded 2021 · 4 employees$2Mraised▾
AI and cloud-based medical device management tool
- Sep 2025Seed$2M
#5
Acquired · Fort Mill, South Carolina · founded 2002 · 118 employees$375Mraised▾
Patient healthcare payment processing solutions for businesses
- Nov 2019Conventional Debt$225M
- Jun 2018Seed—
- May 2018Conventional Debt$150M
#6
Seed · Columbia, South Carolina · founded 2021 · 9 employees$7Mraised▾
Online platform offering insurance plans for pets. The platform offers pet insurance support to claim veterinary bills for unexpected accidents and illnesses. The insurance coverage includes broken bones, torn ligaments, bite wounds, cuts, swallowed objects, X-Rays, MRI, and more.
- Apr 2024Seed$4M
- Aug 2022Seed$3M
#7
Series A · Greenville, South Carolina · founded 2018 · 26 employees$9Mraised▾
Cloud-based precision health platform enabling secure data sharing and patient-centered solutions. The company has developed a software solution that assists treatment workflow management and anomalous testing solutions. The software has features for telehealth integration and smart heat passport generation. The platform has the ability to provide real-time patient data analysis for contact tracking and identification. Users are allowed to share clinical data and information with other team members.
- Oct 2023Series A$9M
#8
Series A · Charleston, South Carolina · founded 2017 · 8 employees$6.9Mraised▾
Innovating neurological disease management with non-invasive blink reflex technology. They are a biotech company pioneering blink reflex technology intended to improve the detection and management of neurological disease and conditions. Their FDA-cleared EyeStat device offers a rapid, objective assessment of neurological function through the blink reflex. This technology enables earlier detection, personalized care, and improved patient outcomes. The i-blink app extends its reach to clinical and telehealth settings, facilitating low-cost, objective blink capturing for enhanced neurological management. They collaborate with pharmaceutical and academic partners to improve diagnosis and clinical trials and empower patients with remote monitoring tools. Their technology provides researchers and doctors insights into neurological activity following a head injury. The company's cloud-based platform ensures secure data management and comprehensive reporting, supporting better decision-making in neurology.
- Jul 2023Series A$1.6M
- Feb 2021Series A$6M
- Nov 2018Conventional Debt$673.4K
- Oct 2017Seed$850K
#9
Series B · Greenville, South Carolina · founded 2005 · 124 employees$44.3Mraised▾
Developer of insulin management software designed to improve the quality of diabetic care. The company's titration software and proprietary algorithms power personalized diabetes treatment recommendations across the continuum of care, enabling hospitals to eliminate hypo and hyperglycemia events.
#10
Series B · Hilton Head Island, South Carolina · founded 2015 · 109 employees$8Mraised▾
PaceMate provides a cloud-based cardiac health remote monitoring platform. The platform provides digital tools with a live EHR integrated platform for remote monitoring of heart health and patient care. On-demand teleconsultations are provided for patients with integrated data management across the cardiology departments.
- Jul 2023Series B—
- Mar 2021Series A$8M
- Sep 2019Seed—
#11
Series A · Greenville, South Carolina · founded 2012 · 171 employees$37.1Mraised▾
ChartSpan, is a patient-facing personal health record tool, which can import records in various electronic formats, can convert paper records into structured data using machine learning and optical character recognition. Using the app patients can request records from providers and send records to others. ChartSpan provides patients, hospitals, clinics, insurers, pharma, public health agencies, researchers and big data companies access to real-time information and meaningful interpretation of healthcare data.
- Jun 2019Series A$15M
- Jun 2017Series A$16M
- Apr 2016Series A$3.2M
- Feb 2015Seed$1.7M
#12
Seed · North Charleston, South Carolina · founded 2009 · 76 employees$2.1Mraised▾
Data-driven solutions for 340B program administration, referral capture, and clinical needs. The company provides comprehensive solutions for healthcare organizations to maximize efficiency, revenue, and patient outcomes. It focuses on the patient journey, leveraging technology with access to EHR and HIE data to provide a complete view of patient health outside the clinic. The company bridges information gaps with robust, multi-source data integrations, automating and digitizing the referral note process. It uses machine learning to clean and standardize patient health records into concise care summaries, delivering detailed continuum of care notes to empower clinical decisions and support 340B referral capture. The technology simplifies and enhances workflow, streamlining patient visits with real-time access to clinical notes and medical history. The company helps identify, close, and document care gaps while tracking and reporting on quality measures, enhancing value-based care performance and optimizing risk adjustments. It offers services like referral capture, clinical tools, and 340B administration, reducing administrative complexity and improving patient outcomes.
- Dec 2023Seed$1M
- Aug 2022Seed$1.1M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of HealthTech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health is moving in the United States
A read on the academic research around Digital Health — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 8,843 United States-affiliated papers.
- Design Intelligence421
- Harvard University383
- Johns Hopkins University295
- University of North Carolina at Chapel Hill206
- University of Washington173
- Health care9→240
- Wearable computer6→129
- Health informatics25→140
- Remote patient monitoring11→76
- Informatics10→60
- Health care36→766
- Health informatics113→495
- Psychological intervention20→320
- Public health34→290
- Intervention (counseling)5→193
- Health care98→1170
- Health informatics213→712
- Public health73→525
- Psychological intervention26→368
- Health administration110→363
Where digital health is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing medical devices patents in the United States
United States medical devices patent filing is accelerating — 666,693 filings from 8,000 assignees (2016–2025), led by Covidien, Boston Scient Scimed, Medtronic; annual filings 63466→63610.
- Covidien29348
- Boston Scient Scimed24762
- Medtronic22396
- Becton Dickinson18249
- Procter & Gamble16178
- Ethicon ENDO Surgery13724
- Kimberly Clark12440
- Ethicon11761
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.