Best Healthcare Companies in South Carolina, United States
The 270 best Healthcare companies in South Carolina, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Care South Carolina.
Ranked: Best Healthcare companies in South Carolina
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Care South Carolina Provider of primary and specialized healthcare services 74Funding top 31%Market top 35%Growth top 35%Innovation top 36% All 7 signals ▾Fundingtop 31% Markettop 35% Growthtop 35% Innovationtop 36% Producttop 46% Techbottom 42% Globalbottom 33% Funding: Raised $256M across 27 rounds · 27 rounds over 19 yrs (1.4/yr) Market: 335 employees (top 14% of Clinics) · Top-5,000,000 web property rank vs industry peers · Fliar Intelligence Index 74/100 | $256M | 12 mo ago | 335 | 1980 | — | TypeScriptPHPZURB Foundation+15 | — | — |
| 2 | ReGenesis Health Care Provider of multi-specialty healthcare services | $142M | 10 mo ago | 76 | 2003 | — | Apple iCloud MailMicrosoft 365PHP+17 | — | — |
| 3 | Tandem Health Sc Provider of multi-specialty healthcare services and a patient portal | $123M | 10 mo ago | 49 | 2018 | — | BootstrapTVSquaredModernizr+5 | — | 2 job openings |
| 4 | South Carolina Office of Rural Health Non-profit organization offers training, education, and technical assistance to rural providers | $84M | 10 mo ago | — | 2003 | Graham Adams CEO | WordPressApple iCloud MailMicrosoft 365+20 | — | 1 job opening |
| 5 | Prismahealth Health system 45Tech top 27%Funding top 30%Growth bottom 44%Market bottom 33% All 6 signals ▾Techtop 27% Fundingtop 30% Growthbottom 44% Marketbottom 33% Newsbottom 32% Globalbottom 32% Tech: 69 technologies across 6/8 capability areas · Cloud: Amazon Cloudfront, Amazon Web Services Funding: Raised $78.4M across 25 rounds · 25 rounds over 9 yrs (2.8/yr) rank vs industry peers · Fliar Intelligence Index 45/100 | $78M | 10 mo ago | 37 | 2017 | — | WordPressApple iCloud MailMySQL+31 | — | 1 job opening · 1 expansion · 2 awards |
| 6 | OBHG Provider of obstetrics and gynecology physician recruiting services | $74M | 115 mo ago | 9 | 2006 | Chris Swain Co-Founder | WordPressApple iCloud MailMicrosoft 365+37 | — | 1 job opening |
| 7 | Conway Medical Center Chain of multi-speciality hospitals | $68M | 47 mo ago | 1,489 1,489 → 1,072 (-28%) | 1928 | — | WordPressMySQLPHP+20 | — | — |
| 8 | St. James Health and Wellness Provider of primary, pediatric, and behavioral healthcare services | $66M | 12 mo ago | — | 1981 | — | Wix eCommerceWixSentry+14 | — | — |
| 9 | Little River Medical Center Provider of medical, dental, behavioral health, and pharmacy services | $66M | 13 mo ago | 166 | 2003 | — | WordPressApple iCloud MailMicrosoft 365+27 | — | 1 job opening · 1 expansion |
| 10 | Rsfh Provider of healthcare information | $60M | 12 mo ago | 5,000 | 1998 | — | WordPress Block EditorWordPress Site EditorWordPress+29 | — | 1 job opening · 3 expansions · 2 awards |
| 11 | SasRx Distributor of dental surgical equipment 21Funding top 44%Market bottom 42%Global bottom 25%Tech bottom 24% All 4 signals ▾Fundingtop 44% Marketbottom 42% Globalbottom 25% Techbottom 24% Funding: Raised $35.0M across 1 rounds · 1 rounds over 14 yrs (0.1/yr) Market: 88 employees rank vs industry peers · Fliar Intelligence Index 21/100 | $35M | 163 mo ago | 88 | 2012 | — | — | — | — |
| 12 | Nubad Nucleic acid-based drug discovery company developing RNA and DNA-targeted therapeutics | $25M | 14 mo ago | — | 2009 | Dev Arya Founder | — | 6 patents Patents concentrated in chemistry & materials | — |
| 13 | AmbioPharm Peptide manufacturing and development services, setting a new standard worldwide | $24M | 93 mo ago | 186 186 → 165 (-11%) | 2006 | — | WordPress Block EditorWordPressApple iCloud Mail+33 | 3 patents Peptide drug synthesis and microsphere formulation for therapeutic peptides | — |
| 14 | Vision Sciences Vision Sciences, a medical device company, develops flexible endoscopes as a control solution to decrease the… | $20M | 184 mo ago | 105 | 1987 | Vision Digital Chief Executive Officer | — | — | — |
| 15 | Paradigm Therapeutics Biopharmaceutical company developing novel therapies to improve the lives of patients with rare and… | $12M | 13 mo ago | — | 2020 | Robert Ryan Founder & CEO | — | — | — |
| 16 | Alpha Genesis Preclinical research services specializing in nonhuman primate models for therapy development | $12M | 101 mo ago | 143 143 → 106 (-26%) | 2003 | — | Squarespace CommerceSquarespaceFacebook Login+11 | — | 1 expansion |
| 17 | MTEC NPO biomedical technology consortium | $12M | 14 mo ago | 11 | 2015 | — | SanityNode.jsTailwind CSS+15 | 4 patents Acoustic isolation and vibration damping solutions for load‑bearing wall structures | — |
| 18 | Blue Sky Specialty Pharmacy Chain of pharmacies | $10M | 45 mo ago | 68 | 2015 | Curt Nesbitt Founder | Apple iCloud MailTypeScriptZone.js+15 | — | — |
| 19 | Afaxys Affordable sexual and reproductive healthcare access for all, mission-driven 37Innovation top 20%Talent top 41%Product top 43%News top 46% All 8 signals ▾Innovationtop 20% Talenttop 41% Producttop 43% Newstop 46% Fundingbottom 48% Techbottom 38% Globalbottom 32% Marketbottom 24% Innovation: 8 product lines Talent: Analyst team rating 4/5 · 1 named leader on record rank vs industry peers · Fliar Intelligence Index 37/100 | $8M | 10 mo ago | 39 39 → 43 (+10%) | 2008 | Ronda Dean Founder & CEO | WordPressPleskApple iCloud Mail+18 | — | — |
| 20 | CTMG Site specific research organisation specialising in Adaptive Investigative Site Management® services | $8M | 118 mo ago | 19 | 2004 | Anton Lewis Usala Founder | — | — | — |
| 21 | Employers Health Network Provider of employee health benefits services | $6M | 121 mo ago | — | 2014 | Orlo Dietrich Co-Founder & CEO | WordPress Block EditorWordPressMySQL+20 | — | — |
| 22 | MedTrust Provider of ambulance services and medical transport | $4M | 83 mo ago | 428 | 2012 | Josh Watts Founder- Board Member | WordPressApple iCloud MailMySQL+20 | — | 1 job opening |
| 23 | AcePre Developer of therapeutics and health resources focused on disease management | $3M | 21 mo ago | 7 | 2017 | Daping Fan Founder | — | — | — |
| 24 | Oasis Health Partners Provider of home healthcare services | $833K | 36 mo ago | 21 | 2023 | Kari Snaza Co-Founder | WordPressApple iCloud MailMicrosoft 365+26 | — | 1 job opening · 1 award |
| 25 | Charleston Surgery Center Standalone ambulatory surgery center | $482K | 102 mo ago | 90 | 1988 | Andrew Sargent CEO | WordPressMySQLPHP+12 | — | — |
| 26 | Outpatient Surgery Center of Hilton Head Standalone general clinic | $381K | 64 mo ago | — | 2002 | — | WordPressMySQLPHP+12 | — | — |
| 27 | Peak Thermal Manufacturer and global supplier of power-efficient cooling systems for urgent medical vaccines | $300K | 33 mo ago | — | 2022 | Jon Nakagawa Founder & CEO | — | — | — |
| 28 | LivN Nsidout Wellness Complex Chain of fitness and wellness centers | $288K | 202 mo ago | — | 2008 | Todd Littleton Founder & Owner | — | — | — |
| 29 | Shine Water Vitamin-enhanced water drinks with electrolytes and antioxidants for optimal hydration | $220K | 101 mo ago | 34 | 2011 | Angel French Co-Founder | ShopifyTailwind CSSVisa+23 | — | 1 expansion |
| 30 | Phi Life Sciences Standalone molecular diagnostics lab | $200K | 102 mo ago | 26 | 2016 | Sawan Hurst Co-Founder & CEO | — | — | — |
| 31 | Sabal Medical Developer of barcode verification software for medication | $125K | 203 mo ago | 5 | 2006 | — | — | — | — |
Top 12 Healthcare companies in South Carolina
#1
Funding Raised · Hartsville, South Carolina · founded 1980 · 335 employees$255.6Mraised▾
Provider of primary and specialized healthcare services. It offers family medicine, pediatrics, women's health, dental care, chiropractic services, and behavioral health services. Diagnostic radiology and laboratory services are also available. The organization operates mobile units to extend care to underserved communities. Additional services include HIV/AIDS care, community outreach programs, and assistance with health insurance. A pharmacy is also part of the organization's offerings
- 2025Grant (prize money)$4.6M
- Jun 2025Grant (prize money)$924.9K
- May 2025Grant (prize money)$78.3K
- Apr 2025Grant (prize money)$2M
#2
Funding Raised · Spartanburg, South Carolina · founded 2003 · 76 employees$142.4Mraised▾
Provider of multi-specialty healthcare services including primary care, dental care, behavioral health, pediatrics, adolescent health, women's health, men's health, and chiropractic care. It also offers home health services, pharmacy services, transportation services, and an agricultural farm worker program. Tele-health services are available. The organization focuses on increasing community access to healthcare and improving patient health outcomes through prevention, education, and case management
- Jul 2025Grant (prize money)$821.2K
- Jul 2025Grant (prize money)$30.1M
- Mar 2025Grant (prize money)$30.1M
- Mar 2025Grant (prize money)$821.2K
#3
Funding Raised · Sumter, South Carolina · founded 2018 · 49 employees$122.5Mraised▾
Provider of multi-specialty healthcare services and a patient portal. It offers services in adult medicine, dental care, family medicine, pediatrics, adolescent health, behavioral health, substance use disorder treatment, immunology, obstetrics and gynecology, and pharmacy services. A family medicine residency program is also available. The company operates a school-based health center and provides access to a patient portal for online appointment booking, prescription refills, and communication with providers. Financial assistance programs, including a sliding fee scale, are offered to ensure affordability.
- Jul 2025Grant (prize money)$16.5M
- Jul 2025Grant (prize money)$16.5M
- 2025Grant (prize money)$1.1M
- May 2025Grant (prize money)$47.9K
#4
Funding Raised · Lexington, South Carolina · founded 2003$83.8Mraised▾
Non-profit organization offers training, education, and technical assistance to rural providers. It empowers communities to address the non-medical drivers of health. The organization focuses on workforce recruitment and retention, community support, and various initiatives including behavioral health, digital equity, and health equity. It supports emergency medical services, rural health clinics, and hospitals.
- Aug 2025Grant (prize money)$3.8M
- 2025Grant (prize money)$497.2K
- Jun 2025Grant (prize money)$1.2M
- Feb 2025Grant (prize money)$8M
#5
Funding Raised · Greenville, South Carolina · founded 2017 · 37 employees$78.4Mraised▾
Health system
- Jul 2025Grant (prize money)$7M
- 2025Grant (prize money)$376.3K
- Apr 2025Grant (prize money)$281.3K
- Mar 2025Grant (prize money)$7M
#6
Funding Raised · Mcclellanville, South Carolina · founded 1981$66.1Mraised▾
Provider of primary, pediatric, and behavioral healthcare services. This entity offers a variety of healthcare services to patients of all ages. Services include routine check-ups, management of complex health issues, and treatment for behavioral health conditions. The organization utilizes an integrated healthcare approach, combining specialists and professionals to provide seamless, patient-centered care. A modern facility with cutting-edge technology supports the delivery of these services
- May 2025Grant (prize money)$28.4K
- Mar 2025Grant (prize money)$2.2M
- Mar 2025Grant (prize money)$21M
- Jan 2025Grant (prize money)$528.5K
#7
Funding Raised · Charleston, South Carolina · founded 1998 · 5000 employees$60.3Mraised▾
Provider of healthcare information
- 2025Grant (prize money)$157.1K
- May 2025Grant (prize money)$6.5M
- Apr 2025Grant (prize money)$4.3M
- Mar 2025Grant (prize money)$6.5M
#8
Funding Raised · Little River, South Carolina · founded 2003 · 166 employees$65.9Mraised▾
Provider of medical, dental, behavioral health, and pharmacy services. The organization offers adult and pediatric medical care, women’s health, and reproductive health services. It also provides assistance for vulnerable individuals and families. The entity delivers community outreach, mobile medical services, and chronic care management.
- Apr 2025Grant (prize money)$2.5M
- Apr 2025Grant (prize money)$500K
- Apr 2025Grant (prize money)$150K
- Mar 2025Grant (prize money)$400K
#9
Funding Raised · Greenville, South Carolina · founded 2009$25Mraised▾
Nucleic acid-based drug discovery company developing RNA and DNA-targeted therapeutics. We identify therapeutic agents targeting nucleic acids, developing novel probes, assays, and small molecule therapeutics for RNA and DNA structures in human disease. Our technologies assist in discovering RNA and DNA-targeted small molecule drugs. We seek academic and private partners for collaborative opportunities to expand our technology. We are a B2B tech company focused on drug discovery, offering products and services in the pharmaceutical industry. Our work has a social impact by targeting diseases through innovative therapeutic approaches.
- Apr 2025Grant (prize money)$521K
- Mar 2025Grant (prize money)$3M
- Jan 2025Grant (prize money)$3.2M
- 2022Grant (prize money)$4.1M
#10
Seed · Charleston, South Carolina · founded 2008 · 39 employees$8Mraised▾
Affordable sexual and reproductive healthcare access for all, mission-driven. This public benefit corporation focuses on ensuring affordable access to sexual and reproductive healthcare as a right, not a privilege. They deliver a full range of contraceptive options and source products and services that providers need at discounted pricing. The company partners with those who serve public health patients, contributing to a healthier, empowered, and just society. They offer exclusive pricing and extensive access to products and services from nationally recognized manufacturers through their GPO and online marketplace. Their mission is driven by values like customer focus, integrity, collaboration, solution orientation, and quality. They aim to be a trusted women’s healthcare partner, providing dependable supply and stable pricing.
- Aug 2025Seed$3M
- Aug 2025Grant (prize money)$5M
#11
Series B · Mt. Pleasant, South Carolina · founded 2020$12.5Mraised▾
Paradigm Therapeutics is a biopharmaceutical company focused on developing innovative treatments for rare and debilitating diseases. With a strong mission to improve patient lives, the company is dedicated to the discovery, development, and delivery of new therapies. Its pipeline includes treatments for rare diseases, such as epidermolysis bullosa, and other indications.
- May 2025Series B$12.5M
#12
Funding Raised · Summerville, South Carolina · founded 2015 · 11 employees$11.9Mraised▾
NPO biomedical technology consortium
- Apr 2025Grant (prize money)$9.8M
- Mar 2025Grant (prize money)$301.8K
- Jan 2025Grant (prize money)$1.8M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Healthcare coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.