Best HealthTech Companies in Waltham, United States
The 54 best HealthTech companies in Waltham, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Alere.
Our analysis of 305 HealthTech companies
$32.1b in tracked funding; 95% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best HealthTech companies in Waltham
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Alere Developer of small rapid diagnostic devices for infectious diseases | $616M | 157 mo ago | 7,011 | 1991 | Ron Zwanziger Founder | — | 10 patents Isothermal SNP detection, microbiome diagnostics, and sample integrity verification using nucleic acid assays. | — |
| 2 | BostonGene 🦄 Developer of cloud-based information and analytics platform to treat cancer | $200M | 51 mo ago | 46 | 2015 | Andrew Feinberg President & CEO | StatamicSentryPHP+19 | 229 patents Cancer immunology profiling and tumor microenvironment analysis using multiplex imaging and cytometry | 1 award |
| 3 | Care.com Provider of an app-based marketplace for booking caregivers | $111M | 120 mo ago | 797 | 2006 | Dave Krupinski Co-Founder | WordPressApple iCloud MailMySQL+20 | — | — |
| 4 | Chrono Therapeutics A transdermal nicotine replacement therapy for smoking cessation. | $82M | 117 mo ago | 31 | 2004 | — | — | — | — |
| 5 | Avilar Provider of drug discovery platform and protein degradation technology | $75M | 67 mo ago | 12 12 → 25 (+108%) | 2020 | Jesse Chen Co-Founder and Advisor | — | — | — |
| 6 | SHYFT Analytics Data Management and analytic solutions for life sciences | $62M | 111 mo ago | 151 | 2005 | — | — | — | — |
| 7 | PatientKeeper Provider of an app-based platform for EHR | $48M | 163 mo ago | 167 | 1996 | George Madrid Co-Founder | SalesforceJavaApache Tomcat+2 | 4 patents Healthcare IT solutions for patient data analytics, mobile context, billing automation, schema integration | — |
| 8 | Imprivata Cloud-based authentication and secure communication solutions for enterprises | $40M | 219 mo ago | 546 | 2002 | Steve Furstenau Director Technical Business Development and Imprivata Founder | DrupalApple iCloud MailMicrosoft 365+23 | 76 patents Hardware-backed enterprise authentication and proximity-based presence detection for secure access | — |
| 9 | Quantia Provider of an online and web community for physicians | $38M | 154 mo ago | 64 | 2004 | — | — | — | — |
| 10 | QuantiaMD Online community for physicians | $38M | 155 mo ago | 1,578 | 2004 | — | — | — | — |
| 11 | MedVentive SaaS based population and risk management tools | $36M | 176 mo ago | 100 | 1997 | — | — | — | — |
| 12 | MDeverywhere RCM, EMR and credentialing solutions to healthcare providers | $28M | 135 mo ago | 271 | 1995 | — | — | — | — |
| 13 | Verscend Provider of data analytics, risk assessment, payment accuracy, and revenue integrity solutions. | $15M | 240 mo ago | 71 | 1996 | Emad Rizk CEO & President | — | — | — |
| 14 | ATENTIVmynd Interactive game based learning for special students | $11M | 145 mo ago | 1 | 2012 | — | — | — | — |
| 15 | Boston Neurosciences Maytag compatible air filters for healthier homes and efficient HVAC systems | $10M | 129 mo ago | 7 | 2013 | Teo Forcht Dagi CEO | — | — | — |
| 16 | X-Chem Provider of small molecule drug discovery platform for researchers | $8M | 162 mo ago | 51 | 2009 | — | WordPress Block EditorWordPressBugHerd+27 | 205 patents DNA‑encoded library screening and heteroaromatic drug candidate discovery | 1 launch · 1 award |
| 17 | Edaris Health Southeast Asia's leading eCommerce platform connecting brands, sellers, and customers | $6M | 102 mo ago | 7 | 2006 | — | — | — | — |
| 18 | Triib End-to-end functional fitness studio management software to engage and grow studios | $3M | 87 mo ago | 5 | 2012 | Nesbitt Hagood CEO | — | — | — |
| 19 | UpToDate Clinical decision support solutions for healthcare professionals and organizations | $1M | 80 mo ago | 19,800 | 1992 | — | Cart FunctionalityBootstrapMustache+13 | 25 patents AI-driven medical database query translation and specialty drug classification systems | — |
| 20 | OpenClinica SaaS-based clinical trial software for electronic data capture and clinical data management | $633K | 40 mo ago | 50 50 → 73 (+46%) | 2006 | — | WordPressApple iCloud MailGoogle Workspace+37 | — | — |
| 21 | ClinicalBox Web based surgical care coordination and patient engagement platform | $600K | 169 mo ago | — | 2011 | Murali Menon Co-Founder & CTO | — | 6 patents Patents concentrated in computing, sensing & instrumentation | — |
| 22 | Bliss Healthcare Compassionate healthcare solutions fostering well-being and positive patient experiences | $500K | 185 mo ago | — | 2009 | Pankaj Khare Chief Executive Officer and Chairman | — | — | — |
| 23 | Gennius Performance intelligence platform for quality metrics, population health, utilization and contracting | $250K | 175 mo ago | 120 | 2002 | Bernadette Downey Founder & CEO | — | — | — |
| 24 | US CareLink Provider of medical software solutions to improve healthcare delivery and patient engagement | $223K | 213 mo ago | — | 2005 | Paul Gertman CEO | — | — | — |
Top 12 HealthTech companies in Waltham
#1
Series B · Waltham, Massachusetts · founded 2015 · 46 employees$200Mraised▾
Developer of cloud-based information and analytics platform to treat cancer. The company combines modern technologies, algorithms, and AI to analyze the molecular profiles of patient tumors and deliver all relevant data directly to medical professionals. The platform (MF Portrait) provides an integrated analysis of each patient's tumor microenvironment, tumor genetic profile, and clinical information.
- Apr 2022Series B$150M
- Apr 2019Series A$50M
#2
Public · Waltham, Massachusetts · founded 1991 · 7011 employees$616.2Mraised▾
Developer of small rapid diagnostic devices for infectious diseases. It provides diagnostics and health management solutions. The company’s products and services are focused on infectious disease, cardiology, oncology, drugs of abuse, and women’s health. Its brands range from over-the-counter tests to lab-based diagnostics to integrated home monitoring solutions.
- May 2013Conventional Debt$425M
- Feb 2013Grant (prize money)$21.6M
- Feb 2013Conventional Debt$20.6M
- Dec 2012Conventional Debt$450M
#3
Acquired · Waltham, Massachusetts · founded 2006 · 797 employees$110.5Mraised▾
Provider of an app-based marketplace for booking caregivers. It enables users to have access to a large network of caregivers such as child care, senior care, and pet care. It also enables people to list themselves as a caregiver. It offers mobile applications for Android and iOS devices.
- Jun 2016Post IPO$46.4M
- Aug 2012Series E$50M
- 2012Series D—
- Oct 2011Series D$25M
#4
Seed · Waltham, Massachusetts · founded 2020 · 12 employees$75.3Mraised▾
Provider of drug discovery platform and protein degradation technology. The company has built a proprietary technology platform to develop novel extracellular protein degraders called ATACs that shuttle disease-causing proteins from circulation to the endolysosome where the unwanted proteins are degraded. It provides applications in a broad range of diseases.
- Dec 2020Seed$75.3M
#5
Deadpooled · Waltham, Massachusetts · founded 2004 · 31 employees$82.2Mraised▾
Chrono Therapeutics has developed a device with programmable passive transdermal drug delivery (TDD) system. Their first product, StopSmart, is a wearable wrist, arm, or as an adhesive patch, that helps a user in smoking cessation. The wearable is attached to user's body and is controlled by a smartphone app where the user can set up a time to start administering nicotine. Based on past start times devices releases nicotine in a controlled amount at different interval of time rather than continuously, throughout the day over a 10-week period. The drug delivery system is coupled with real-time behavioral support therapy via the connected smartphone app. The platform could also be used for delivery of various other drugs for conditions including Parkinson’s, asthma, and ADHD. Chrono is planning to apply for approval in 2016 and launch device in 2017.
- Sep 2016Series B—
- Sep 2016Series B$47.6M
- Aug 2015Grant (prize money)$2.3M
- Mar 2015Series A$100K
#6
Acquired · Waltham, Massachusetts · founded 2005 · 151 employees$61.5Mraised▾
Data Management and analytic solutions for life sciences. The analytics platform integrates clinical, commercial, and real-world evidence data to provide patient-centric intelligence. The platform is used by pharmaceutical, biotech, and medical devices enterprises and features product analytic solutions for Specialty, Launch, Real World Evidence, Market Access, Rare Disease, and Sales.
- Mar 2017Series B$7.5M
- Aug 2016Series B$20M
- Apr 2014Series A$19M
- Dec 2013Series A$15M
#7
Acqui-Hired · Waltham, Massachusetts · founded 1996 · 167 employees$47.8Mraised▾
PatientKeeper is a provider of an app-based platform for EHR. It provides a physician information system provider aims at cost-effectively deliver information to enhance patient care and safety, optimize expenditures, improve staff productivity, and increase revenue. The software is available on a range of devices from Smartphones to tablets to laptops. The mobile app edition of the PatientKeeper Computerized Patient Order Entry (CPOE) system allows providers to order labs, radiology, medications, and similar services for their patients across all hospital departments.
- Nov 2012Series G$900K
- Jun 2012Series G$6.2M
- Jun 2012Conventional Debt$2M
- Dec 2011Series G$6M
#8
Acqui-Hired · Waltham, Massachusetts · founded 1997 · 100 employees$36.3Mraised▾
MedVentive (acquired by McKesson Corporation) provides technology solutions that enable physician groups, health plans and self-insured employers to understand and manage the quality, cost and efficiency of providing patient care. Solutions offered: MedVentive Population Manager, a clinical tool clinical integration and population management; and MedVentive Risk Manager, helps to analyze an improve cost and quality challenges. MedVentive was formerly known Provider Service Network.
- Oct 2011Series D$12M
- Aug 2011Series C$900K
- May 2011Series C$1.5M
- Feb 2010Series C$10M
#9
Acqui-Hired · Waltham, Massachusetts · founded 2004 · 64 employees$38Mraised▾
Quantia is a provider of an online and web community for physicians. It offers QuantiaMD, an online and Web community for physicians. The company offers digital marketing campaigns that help clients build brands, increase the share of mind, and empower better decision making among their target audiences. Its integrated campaigns include strategy, solution design, customer segmentation, advertising, and actionable analytics to impact target behavior and help clients achieve their goals. The company also provides access to Univadis, a healthcare professional community; and MedHelp, a consumer online health community, and platform.
- Sep 2013Series B$10M
- Nov 2012Series B$14.4M
- Mar 2009Series A$4.6M
- Sep 2008Series A$5M
#10
Acquired · Waltham, Massachusetts · founded 2004 · 1578 employees$38Mraised▾
QuantiaMD is a social learning and collaboration platform for physicians. The platform, available on web and mobile, enables physicians to learn from top experts and collaborate on a range of topics.The company claims to have over over 225,000 physicians in its network. The company was acquired by Physicians Interactive (now Aptus Health) in July 2015.
- Aug 2013Series B$10M
- Nov 2012Series B$14.4M
- Mar 2009Series A$4.6M
- Sep 2008Series A$5M
#11
Acquired · Waltham, Massachusetts · founded 2002 · 546 employees$40.5Mraised▾
Cloud-based authentication and secure communication solutions for enterprises. It provides user authentication, application access, and compliance reporting across multiple computing environments. The outcome is to manage workflows, security, and compliance with government regulations.
- Apr 2008Series C$15M
- Feb 2006Series B$12M
- 2002Series A$13.5M
#12
Acqui-Hired · Waltham, Massachusetts · founded 1995 · 271 employees$28Mraised▾
MDeverywhere, formerly known as Med e-Manager offers revenue cycle management (RCM), electronic medical record and credentialing solutions to physicians. The company's RCM solution includes ICD-10 ready, purpose-built, cloud-based practice management software, coding rules engines, contract monitoring tools and full-scope claims management and back-office solutions. Claims to serve over 7,000 physicians across U.S, including solo practices, group practices, large faculty practices, and hospitals across over 40 different specialties. Merged with e-MDs in March, 2015 after the acquisition of eMDs by Marlin Equity Partners.
- Mar 2015PE—
- May 2001Series B$15M
- Feb 2000Series A$11M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of HealthTech coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health is moving in the United States
A read on the academic research around Digital Health — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 8,843 United States-affiliated papers.
- Design Intelligence421
- Harvard University383
- Johns Hopkins University295
- University of North Carolina at Chapel Hill206
- University of Washington173
- Health care9→240
- Wearable computer6→129
- Health informatics25→140
- Remote patient monitoring11→76
- Informatics10→60
- Health care36→766
- Health informatics113→495
- Psychological intervention20→320
- Public health34→290
- Intervention (counseling)5→193
- Health care98→1170
- Health informatics213→712
- Public health73→525
- Psychological intervention26→368
- Health administration110→363
Where digital health is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing medical devices patents in the United States
United States medical devices patent filing is accelerating — 666,693 filings from 8,000 assignees (2016–2025), led by Covidien, Boston Scient Scimed, Medtronic; annual filings 63466→63610.
- Covidien29348
- Boston Scient Scimed24762
- Medtronic22396
- Becton Dickinson18249
- Procter & Gamble16178
- Ethicon ENDO Surgery13724
- Kimberly Clark12440
- Ethicon11761
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.