Best Life Sciences Companies in Indianapolis, United States
The 72 best Life Sciences companies in Indianapolis, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Greenlight Guru.
Our analysis of 164 Life Sciences companies
$34.7b in tracked funding; 83% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Life Sciences companies in Indianapolis
| # | Company | Disclosed funding | Employees | Founder | Tech stack | Stage | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|
| 1 | Greenlight Guru Developer of quality management system software for the medical device industry | $121M | 154 154 → 139 (-10%) | Ed Holmes CEO | HubSpot CMS HubSentryApple iCloud Mail+29 | Series A | — | — |
| 2 | SpectronRx Provider of therapeutic and diagnostic isotope solutions 45Funding top 21%Growth top 28%Moat top 45%News top 46% All 11 signals ▾Fundingtop 21% Growthtop 28% Moattop 45% Newstop 46% Markettop 47% Talentbottom 49% Patentsbottom 41% Techbottom 37% Globalbottom 35% Partnersbottom 35% Innovationbottom 23% Funding: Raised $85.0M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) Growth: Web rank 50,000,000 → 10,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 45/100 | $85M | 93 | John Zehner CEO | WordPressMySQLPHP+14 | Series C | 2 patents Radium-226 extraction from phosphogypsum waste streams | — |
| 3 | NICO Developer of technology for the field of neurological corridor surgery | $62M | 49 | — | WordPressMySQLPHP+17 | Acquired | 293 patents Minimally invasive surgical access devices and illumination-enabled instrument cannulas | — |
| 4 | Biosynthetic Technologies Producer of bio-based green oils | $52M | 14 14 → 11 (-21%) | Mark Miller CEO | WordPress Block EditorWordPressMySQL+28 | Acquired | 198 patents Synthetic estolide-based lubricants and base oils with enhanced oxidative stability | — |
| 5 | Scioto Biosciences Developer of therapies for diabetes, neurological disorders, gastrointestinal and others using probiotics | $34M | 10 | Jim Schulz Co-Founder & CFO | — | Series B | — | — |
| 6 | Chondrial Therapeutics Biotechnology firm developing treatments for rare diseases using intracellular delivery platform | $23M | 21 | Mark Payne Co-Founder | — | Series A | — | — |
| 7 | FAST BioMedical Fluorescent in-vivo markers to measure plasma volume and mGFR | $22M | 2 | — | — | Deadpooled | 26 patents Quantitative biomedical diagnostics using fluorescent markers and blood/renal volume measurement. | — |
| 8 | Esanex Developing anticancer heat shock protein (HSP) inhibitors | $19M | — | Steven Hall CEO & President | — | Deadpooled | 31 patents Novel heterocyclic benzamide compounds for anticancer combination therapies | — |
| 9 | Recovery Force Wearable massage compression sleeves and wraps | $16M | 15 | — | — | Series B | 59 patents Wearable medical compression devices for deep vein thrombosis prevention and therapy | — |
| 10 | Gate Neurosciences Developer of therapies for a broad range of neuropsychiatric and cognitive disorders | $16M | 12 | Michael McCully Co-Founder & CEO | — | Funding Raised | — | — |
| 11 | Indigo BioAutomation Automated data analysis, management and integration solutions | $12M | 27 | — | WordPressApple iCloud MailMicrosoft 365+25 | Series B | — | — |
| 12 | Toralgen Developer of oral formulations of anti-diabetic drugs | $10M | 9 | — | — | Seed | — | — |
| 13 | SonarMed Global healthcare technology company specializing in medical devices and therapies | $10M | 6 | — | — | Acqui-Hired | 38 patents Acoustic sensing for catheter navigation and respiratory device monitoring in medical applications. | — |
| 14 | Vascugen Regenerative medicine company developing cell therapies for vascular diseases and tissue engineering | $10M | 10 | Carter Cliff Founder & CEO | — | Series A | 2 patents Engineered vasculogenic cell therapies for treating perfusion and vascular disorders. | — |
| 15 | BioStorage Technologies Life sciences solutions provider accelerating breakthroughs in therapies and sample management | $9M | 120 | — | — | Acquired | — | — |
| 16 | Apexian Pharma Developer of small molecule therapeutics for the treatment of cancer | $8M | 4 | — | — | Series A | — | — |
| 17 | Sexton Biotechnologies Developer of portfolio of process and handling solutions for pharma sectors | $5M | 20 | Monica Wight Co-Founder | — | Acquired | 14 patents Cryogenic biopreservation containers and pathogen‑reduced platelet manufacturing technologies | — |
| 18 | VoCare Remote patient monitoring solutions enhancing value-based healthcare through connected medical devices | $5M | 2 | — | — | Series A | 2 patents Location-based personal emergency response devices and systems for real-time safety alerts | — |
| 19 | Mitogen Growth factor-infused orthopedic implants | $4M | — | Nelson Scharadin Co-Founder & CEO | — | Deadpooled | — | — |
| 20 | Early Is Good Developer of multi-omic platform for biomarker detection to transform healthcare | $4M | 5 | Asel Liyanage Co-Founder | — | Seed | — | — |
| 21 | HB Therapeutics Developer of therapeutic drugs designed to make anti-cancer and anti-aging medicines | $4M | — | Anita Bellail Founder | — | Funding Raised | 1,876 patents Targeted protein degradation (PROTACs) and exosome-based therapies for oncology and neurodegeneration | — |
| 22 | VitaCyte Tissue dissociation enzymes | $4M | 18 | — | — | Funding Raised | — | — |
| 23 | EndGenitor Technologies Developing therapies using isolated adult stem /progenitor cells obtained from umbilical cord blood. | $2M | — | Ron Henriksen Co-Founder | — | Deadpooled | 4 patents Specialized endothelial progenitor cell therapies and enhanced hematopoietic stem cell engraftment | — |
| 24 | OpalGenix Developer of a genetic test for precision opioid and pain management | $2M | 2 | Senthilkumar Sadhasivam Founder | — | Funding Raised | — | — |
| 25 | Rimedion Gene therapies for rare diseases such as Fanconi Anemia. | $2M | — | Butch Mercer Co-Founder & ex-CEO | — | Deadpooled | — | — |
| 26 | Neurofox Developing cell-free therapeutic factor for the treatment of neurological conditions. | $2M | — | Brian Johnstone Co-Founder & Director of R&D | — | Seed | — | — |
| 27 | Confluence Pharmaceuticals Developing drugs to treat Fragile-X and Austism Spectrum Disorders | $2M | 4 | — | — | Seed | — | — |
| 28 | GrannuS Developer of small molecule inhibitors for the treatment of oncology | $1M | 2 | Sanket Mishra Co-Founder | — | Funding Raised | 39 patents Integrated hydrogen, power, and fertilizer production using carbon capture and fuel‑cell by‑products | — |
| 29 | Ultra Ankle Product development company for injury prevention in sports | $1M | 3 | — | Cart FunctionalityWooCommerceWordPress+26 | Public | — | — |
| 30 | NERx BioSciences Discovery and development of targeted therapeutics for cancer | $1M | 2 | — | — | Seed | — | — |
| 31 | Arkley Biotek Provider of blood-based diagnostic for early detection of Alzheimer's disease | $1M | 5 | Paul Hyslop Founder & GM | — | Funding Raised | — | — |
| 32 | Theratome Bio Regenerative medicine enhanced by AI, focusing on organ transplant and dry eye | $800K | 1 | Michael Coleman CEO & President | — | Seed | — | — |
| 33 | ImmuneWorks Autoimmune Lung Diseases | $735K | 2 | — | — | Seed | — | — |
| 34 | Butterfly BVM Manufacturer of improved bag-valve-mask devices for CPR | $556K | 5 | — | Wix eCommerceWixSentry+15 | Funding Raised | — | 1 launch |
| 35 | Xylogenics Synthetic biology company engineering yeast for efficient fuel ethanol production | $525K | 6 | Cary Woods Co-founder | — | Seed | 18 patents Engineered Saccharomyces yeast enabling glucoamylase‑free oligosaccharide fermentation to ethanol | — |
| 36 | Maaguzi Web and mobile based patient outcome reporting | $375K | — | Raul Zavaleta ex-CEO | — | Acquired | — | — |
| 37 | Cascade Metrix Automating critical care analysis with innovative blood parameter measurement technology | $350K | — | Kislaya Kunjan Co-Founder and Chief Technology Officer | — | Funding Raised | — | — |
| 38 | bionode Envato: Creative assets, tools, and services for creative professionals | $250K | 6 | Pedro Irazoqui Co-Founder & CTO | — | Seed | — | — |
| 39 | Compact Medical Solutions Developer of breathing device | $235K | — | Gustavo Amorim Co-Founder | — | Seed | — | — |
| 40 | Rehab Medical Provider of custom mobility equipment including wheelchairs and related accessories | $146K | 279 279 → 690 (+147%) | — | Cart FunctionalityWix eCommerceWix+24 | Funding Raised | — | — |
| 41 | BioReact Platform offering AI bioprocess parameter optimization software | $120K | — | Joanna Lipinski Co-Founder & CTO | Cart FunctionalitySquarespace CommerceSquarespace+13 | Seed | — | — |
| 42 | Fertiligent Provider of in-vitro fertilization device for artificial insemination | $110K | — | Amnon Weichselbaum Co-Founder And Scientific Director | — | Funding Raised | — | — |
| 43 | Insignum AgTech Developer of plant signaling technology for optimized crop management decisions | $100K | 2 | Kyle Mohler Founder & CEO | — | Seed | 7 patents Genetically engineered plants for rapid detection of pathogenic diseases in agriculture | — |
Top 12 Life Sciences companies in Indianapolis
#1
Series C · Indianapolis, Indiana · founded 2004 · 93 employees$85Mraised▾
SpectronRx is a provider of therapeutic and diagnostic isotope solutions. It provides radionuclides and custom theranostic contract manufacturing like monoclonal antibody labelling, peptides, radiolabeling of molecules and chemical entities, and aptamers.
- Apr 2026Series C$85M
#2
Funding Raised · Indianapolis, Indiana · founded 2020 · 2 employees$2.4Mraised▾
Developer of a genetic test for precision opioid and pain management. The GPS-Opioid technology is a pre-operative laboratory-developed test that has polygenetic and intelligent analytics for the prediction of opioid-related adverse effects, and severe surgical pain.
- May 2025Grant (prize money)$325.2K
- Feb 2025Grant (prize money)$374.4K
- Aug 2023Grant (prize money)$644.4K
- May 2023Grant (prize money)$325.2K
#3
Seed · Indianapolis, Indiana · founded 2023$120Kraised▾
Platform offering AI bioprocess parameter optimization software. It helps researchers understand bioreactor conditions to enable cell thriving. It provides an AI that is trained on data points covering various cells. It analyzes, models, and optimizes crucial parameters such as temperature, pH, nutrient concentrations, media composition, and fermentation times.
- Feb 2026Seed—
- Sep 2024Seed$120K
- Seed$1.1M
#4
Seed · Indianapolis, Indiana · founded 2019 · 5 employees$4Mraised▾
Developer of multi-omic platform for biomarker detection to transform healthcare. The platform facilitates simultaneous detection of DNAs, RNAs, proteins, and small molecules without extraction or amplification. It offers ultra attomolar sensitivity and simplified analysis readout from a basic plate reader. The company focuses on oncology product development, including bladder cancer monitoring and early prostate cancer detection.
- Sep 2024Grant (prize money)$821.8K
- Nov 2022Seed$4M
#5
Seed · Indianapolis, Indiana · founded 2016$235Kraised▾
Compact medical solution is the developer of a breathing device. The platform has developed the bag-valve-mask resuscitator (BVM) device that protects patients’ lungs from hyperventilation and barotrauma.
- Sep 2025Seed$200K
- Nov 2023Seed$685K
- Sep 2020Seed$150K
- Nov 2019Seed$85K
#6
Acquired · Indianapolis, Indiana · founded 2007 · 49 employees$62Mraised▾
Developer of technology for the field of neurological corridor surgery. It offers products that allow access through smaller openings and resection of soft tissue abnormalities. It includes BrainPath (brain lesion access), Myriad handpieces console system, and TRIOwand fluid management wand.
- Sep 2022Series B$12.6M
- Nov 2018Series B$12.5M
- Jun 2016Conventional Debt$8M
- Feb 2016Series B$15M
#7
Seed · Indianapolis, Indiana · founded 2019 · 2 employees$100Kraised▾
Developer of plant signaling technology for optimized crop management decisions. It provides genetic modification solutions for crops. It leverages gene editing technology to create crop traits that are bred into seeds, enabling growers to identify specific plant stresses. It facilitates farmers to optimize growth and deal with the issue of early-stage infections.
- Sep 2025Seed$2.4M
- Apr 2025Seed$4.2M
- Dec 2023Conventional Debt$600K
- Mar 2023Seed—
#8
Seed · Indianapolis, Indiana · founded 2009 · 2 employees$1.3Mraised▾
Discovery and development of targeted therapeutics for cancer. The company is developing a new generation of cancer drugs that target specific cellular processes to detect and eliminate cancer cells. The company is developing drugs for lung and ovarian cancers.
- Aug 2024Grant (prize money)$1.1M
- Nov 2021Seed$200K
- Nov 2021Conventional Debt—
- Jan 2019Seed$850K
#9
Series A · Indianapolis, Indiana · founded 2013 · 154 employees$121.2Mraised▾
Developer of quality management system software for the medical device industry. The software facilitates product development, quality assurance, and clinical data management. It offers solutions for risk assessment, regulatory submissions, audit readiness, and post-market quality management. The software provides features for design control, risk management, and change management.
- Jun 2021Series A$120M
- Feb 2015Seed$1.2M
#10
Acqui-Hired · Indianapolis, Indiana · founded 2005 · 6 employees$10.1Mraised▾
Global healthcare technology company specializing in medical devices and therapies. It offers a wide array of products and solutions for healthcare professionals and patients. The company focuses on various therapeutic areas, including cardiac rhythm management, cardiovascular, diabetes, neurological, spinal, and respiratory care. It provides access to instruments, bladder and bowel solutions, surgical energy, surgical navigation, and patient monitoring systems. The company supports healthcare providers with digital ordering, electronic data interchange, and training programs. It also offers patient services, including remote monitoring and product support. The company is committed to innovation, inclusion, diversity, and health equity, aiming to improve lives through medical technology.
- May 2023Grant (prize money)$322.9K
- Sep 2022Grant (prize money)$812.3K
- May 2017Series C$3M
- Jul 2016Conventional Debt$861.3K
#11
Series B · Indianapolis, Indiana · founded 2017 · 10 employees$33.8Mraised▾
Developer of therapies for diabetes, neurological disorders, gastrointestinal and others using probiotics. The platform develops biofilm formation over the polysaccharide microspheres which helps the probiotics for adhesion to the intestinal mucosa for a longer time.
- 2021Series B$5.5M
- Aug 2020Series B$26.5M
- Aug 2019Grant (prize money)$2.3M
- 2018Series A—
#12
Acquired · Indianapolis, Indiana · founded 2012 · 14 employees$52.2Mraised▾
Manufacturer of bio-based green oils. They produce synthetic oils, called estolides, from organic fatty acids found in various bio-derived oils. These are bio-degradable & non-toxic and can be used as the primary base oil of a lubricant formulation, a component of a base oil co-blend, or as an additive. These oils have applications in many industries, such as cosmetic, chemicals, food-grade lubricants, car motor oil, and marine lubricant.
- May 2019Series A$9.5M
- Feb 2017Conventional Debt$16.5M
- Oct 2014Series A$12M
- Jul 2014Series A—
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Life Sciences coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
What Indianapolis researches in biotechnology
- Indiana University – Purdue University Indianapolis18
- Indianapolis Zoo1
- University of Indianapolis1
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.