Best Life Sciences Companies in Tokyo, Japan

Medical devices and therapeutic platforms using sound waves. It is a medical device startup that aims to implement low-invasive therapeutic platform technology.

Funding rounds

• May 2026Series C$17M

Founders & team

Hiroaki ShimokawaFounderKentaro ShiratsuchiCEO

Investors

Sumitomo Heavy Industries, IGlobe Partners, Fiducia, Tohoku University Venture Partners

Tech stack

Apache Http ServerApple Icloud MailCdnjsCloudflareCreatejsGoogle Analytics

Developer of high intensity focused ultrasound treatment systems. The companys system uses cavitation bubbles to enhance treatment efficacy and visualize the treatment process using heating systems. It offers treatment of pancreatic cancer using clinical trial assessing methods. It involves treating disease with high-energy ultrasound waves on a targeted area to destroy the cancer cells.

Funding rounds

• Apr 2026Series B$18M
• Nov 2022Series B$17M
• Jun 2021Series A$4.8M

Founders & team

Tohru SatohFounder & CEO & President

Investors

Fast Track Initiative, SBI Investment, Mitsubishi UFJ Capital, MAKOTO Capital, Higin Capital, FFG Venture Business Partners

Tech stack

Animate.CssCdnjsCloudflareGoogle AnalyticsGoogle Font ApiGoogle Hosted Libraries

Direct-to-consumer tests for intestinal microbiome profiling. Its flagship product Mykinso uses next-generation sequencing and proprietary bioinformatics for metagenomic profiling of the customer's stool sample. Users can purchase the fecal sample kit, register it online and mail the sample to the company. In addition, they are encouraged to fill in a lifestyle-related questionnaire that Cykinso plans to use in future research. Results can be viewed on the company website or the accompanying app.

Developer of therapeutics drugs for eye diseases. The company is developing a regenerative gene therapy drug that is injected into the eyeball and a hypoxia-inducible factor (HIF) inhibitor to treat retina-related diseases. The company has developed a pipeline for age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa.

Funding rounds

• Apr 2026Series A$8.2M
• Dec 2023Series A—
• Jun 2023Series A$9.3M
• Feb 2022Seed$2.6M

Founders & team

Yusaku KatataCo-Founder & CEO

Investors

Remiges Ventures, ANRI, Real Tech Holdings, DBJ Capital, QB Capital, SMBC Venture Capital

Tech stack

Core-JsGoogle Font ApiGoogle WorkspaceHstsOpen GraphSakura Internet

Developer of therapeutics based on human gut microbiome. It has a GMP-compliant manufacturing platform for fecal microbiota transplantation (FMT) therapies that transfers healthy gut bacteria into patients to treat diseases such as cancer, ulcerative colitis, parkinson’s disease, and immune-related diseases.

Funding rounds

• Jan 2026Series B$6.4M
• Sep 2025Series B$5.5M
• Jul 2025Series B$10.2M
• Jun 2023Series A$1.5M

Founders & team

Shinji FukudaCo-Founder & Senior Scientific AdvisorTakuji YamadaCo-Founder & Senior Scientific AdvisorTaku NakaharaCo-Founder & CEO

Investors

JIC Venture Growth Investments, FTI, Keio Innovation Initiative, JAFCO, Mizuho Capital, SMBC Venture Capital

Tech stack

Amazon CloudfrontAmazon SesAmazon Web ServicesApple Icloud MailCdnjsCloudflare

Developer of hydrogel technology related to biomaterials and medical applications. The company specializes in developing bio-materials using Ameba Hydrogel technology for environmental, chemical, and medical applications based on life science and bioengineering.

Funding rounds

• Apr 2026Seed$1.3M
• Feb 2024Seed$1.3M

Founders & team

Shin YoshidaCo-Founder & CEOMadoka TakaiCo-Founder

Investors

WUV, Soken Chem

AI-based medical devices for diagnosis and treatment of heart diseases. The company has developed an automated analysis system that assists healthcare professionals in clinical decision support and treatment. The device diagnoses the heart conditions by analyzing the ECG waveforms and creating a model using deep learning techniques.

Funding rounds

• Mar 2026Series B—
• Nov 2025Series B—
• Mar 2024Series A—
• Aug 2022Series A$3.2M

Founders & team

Yuichi TamuraCEO

Investors

Samurai Incubate, Daiwa Corporate Investment, SMBC Venture Capital, Gemseki, ANRI, Shizuoka Bank

Tech stack

All In One SeoContact Form 7Core-JsGoogle AnalyticsGoogle Font ApiGoogle Workspace

Developer of proton beam therapeutic devices for the treatment of cancer. The company is involved in the development of an ultra-small proton beam cancer treatment device that uses a beam of protons to deliver radiation directly to the tumor cell. It is a cancer-killing machine that can target a patient's tumor with a sub-millimeter precision while sparing nearby healthy tissues and minimizing side effects.

Funding rounds

• Oct 2025Series B$8.8M
• Jun 2022Series A$13.1M

Founders & team

Takuji FurukawaPresident & CEO

Investors

Keio Innovation Initiative, Oita Venture Capital, Mitsubishi UFJ Capital, Pegasus Tech Ventures

Developer of cell therapies for the treatment of blood cancer. The company is developing hematopoietic stem cell therapy by using amplification technology for the treatment of blood cancers such as leukemia, malignant lymphoma, multiple myeloma, and intractable blood diseases such as aplastic anemia.

Funding rounds

• Oct 2025Series B$7.2M
• May 2024Series A$3M

Founders & team

Masatoshi SakuraiCo-FounderSatoshi YamazakiCo-FounderMotoo WatanabeCo-Founder

Investors

Osaka University Venture Capital, UTEC, Techno Science Japan Co., Ltd., Joyo Capital Partners, Amed

Developer of cell sorting and single cell profiling platforms. The business provides tools for cell therapy, disease profiling, and drug discovery applications. The platforms combine fluorescence flow cytometry with morphological profiling and artificial intelligence. The business also offers related consumables and instrument services.

Funding rounds

• Aug 2024Series C$14.9M
• Nov 2023Series C$24M
• Nov 2023Grant (prize money)—
• May 2021Series B$26M

Founders & team

Ryoichi HorisakiCo-FounderSadao OtaCo-Founder & CTOIssei SatoCo-Founder

Investors

SPARX Group, Sysmex, Sumitomo Mitsui Trust Investment, SBI Group, ITV, Berkeley SkyDeck

Tech stack

Amazon Web ServicesBootstrapCloudflareCloudflare Bot ManagementContact Form 7Core-Js

Provider of AI-based analysis software for pathology image diagnosis. Pidport an AI-based software allows the user's to instantly screen pathological tissues and cells. The pathological image data and case information can be managed and stored on the cloud server.

Funding rounds

• May 2025Series A$3.3M
• Apr 2024Series A$5.5M

Founders & team

Osamu IizukaFounder & CEO

Investors

Nikon, Migalo, AngelNavi, Psp, Niremia, Plug and Play Tech Center

Tech stack

Amazon Web ServicesCore-JsFont AwesomeGoogle AnalyticsGoogle Tag ManagerGoogle Workspace

Developer of a device for cancer detection. The company has developed a novel device that is used to collect and separate the microRNA secreted from cancer cells present in the urine. The device uses a combination of zinc oxide nanostructures and microflow channel technologies for the process and early cancer detection.

Funding rounds

• Apr 2025Series C$22M
• Dec 2024Series C$6.4M
• Mar 2024Series B—
• Apr 2022Series B—

Founders & team

Takao YasuiCo-FounderRyuichi OnoseCo-Founder & CEO

Investors

Toyoda Gosei, Aflac Innovation Partners, ANRI, Daiwa Corporate Investment, Mori Trust, Saisei Ventures

Tech stack

Amazon SesAmazon Web ServicesApple Icloud MailCore-JsFacebook PixelGoogle Analytics