Best Oncology Companies in Maryland, United States
The 110 best Oncology companies in Maryland, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Viela Bio.
Our analysis of 50 Oncology companies
$16.3b in tracked funding; 86% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Oncology companies in Maryland
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|
| 1 | Viela Bio Developer of biologics for treating severe inflammation and autoimmune diseases | $357M | 84 mo ago | 170 | 2017 | — | 242 patents Immunomodulatory antibody/scaffold therapeutics targeting CD40L, CD19, Ilt7 for autoimmune diseases | — |
| 2 | Delfi Diagnostics Provider of DNA sequencing for cancer detection 67Funding top 17%Patents top 24%AI top 28%Moat top 28% All 11 signals ▾Fundingtop 17% Patentstop 24% AItop 28% Moattop 28% Innovationtop 32% Talenttop 42% Growthtop 48% Marketbottom 49% Techbottom 47% Globalbottom 36% Newsbottom 33% Funding: Raised $332M across 5 rounds · 5 rounds over 7 yrs (0.7/yr) Patents: 52 patents matched (strict assignee match) · 52 filings since 2022 vs 0 in 2017-21 rank vs industry peers · Fliar Intelligence Index 67/100 | $332M | 6 mo ago | 197 | 2019 | Victor Velculescu Founder and Board of Directors | 52 patents Non-invasive cancer detection and monitoring via cell‑free DNA fragmentation profiling | 1 job opening · 1 partnership · 3 awards |
| 3 | Sirnaomics Developer of RNA based therapeutics for the treatment of cancer and fibrosis disease 80Patents top 14%Funding top 15%Innovation top 17%Growth top 28% All 9 signals ▾Patentstop 14% Fundingtop 15% Innovationtop 17% Growthtop 28% Moattop 35% Markettop 46% Talentbottom 49% Globalbottom 48% Newsbottom 21% Patents: 277 patents matched (strict assignee match) · 191 filings since 2022 vs 63 in 2017-21 Funding: Raised $267M across 14 rounds · 14 rounds over 19 yrs (0.7/yr) rank vs industry peers · Fliar Intelligence Index 80/100 | $267M | 9 mo ago | 88 | 2007 | Patrick Lu President and CEO | 277 patents siRNA therapeutics and nanoparticle delivery systems for cancer and viral diseases | 1 launch |
| 4 | Personal Genome Provider of advanced technology solutions for cancer genome analysis | $252M | 64 mo ago | 109 | 2010 | — | 143 patents Patents concentrated in chemistry & materials | — |
| 5 | Barinthus Biotherapeutics Developer of T-cell immunotherapeutics to treat multiple diseases | $210M | 29 mo ago | — | 2016 | Adrian Hill Co-Founder | 33 patents Peptide vaccine nanocarriers for cancer immunotherapy and targeted drug delivery | — |
| 6 | Arcellx Developer of T cell-mediated anti tumour therapy | $200M | 40 mo ago | 130 130 → 224 (+72%) | 2014 | David Hilbert Founder & Co-CEO | 112 patents Engineered D-domain polypeptides for multifunctional immune cell therapy applications | — |
| 7 | Clasp Therapeutics Developer of T cell therapeutics for the treatment of cancer | $150M | 27 mo ago | — | 2020 | Shibin Zhou Co-Founder | — | 1 award |
| 8 | MacroGenics Developer of novel biologics for the treatment of autoimmune disorders, cancer and infectious disease | $126M | 87 mo ago | 339 339 → 378 (+12%) | 2000 | Scott Koenig President and CEO | 1,258 patents Therapeutic antibodies and ADCs targeting immune checkpoints (PD‑1, CD3, ADAM9, B7‑H3). | — |
| 9 | Immunomic Therapeutics Vaccines for allergy, cancer and infectious disease. 57Funding top 24%Growth top 28%Product top 30%Innovation top 34% All 9 signals ▾Fundingtop 24% Growthtop 28% Producttop 30% Innovationtop 34% Moattop 39% Techbottom 44% Marketbottom 37% Globalbottom 37% Newsbottom 21% Funding: Raised $97.9M across 14 rounds · 14 rounds over 15 yrs (0.9/yr) Growth: Headcount 38 → 51 (+34%) across vintages · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 57/100 | $98M | 12 mo ago | 51 | 2005 | — | — | — |
| 10 | Sensei Biotherapeutics Developer of immunotherapies for the treatment of cancer | $94M | 65 mo ago | 27 | 1999 | John Celebi Chief Executive Officer | 19 patents Immuno‑oncology antibodies and bispecifics targeting the VISTA checkpoint for cancer therapy | — |
| 11 | DEKA Biosciences Developer of therapeutics for cancer and inflammatory diseases | $76M | 40 mo ago | 30 | 2018 | Pavel Khrimian Co-founder & CBO | 104 patents Engineered IL-10 cytokine fusions to mitigate cytokine release syndrome in CAR‑T/bi‑specific immunotherapies | — |
| 12 | Georgiamune Developer of immunotherapeutics to treat cancer and autoimmune diseases | $75M | 34 mo ago | 14 14 → 30 (+114%) | 2019 | Samir Khleif Founder & CEO | 122 patents Patents concentrated in chemistry & materials | — |
| 13 | CASI Pharmaceuticals Developer of therapeutics for the treatment of cancer 60Product top 19%Funding top 26%Growth top 36%Innovation top 38% All 10 signals ▾Producttop 19% Fundingtop 26% Growthtop 36% Innovationtop 38% Fin. healthtop 43% Markettop 46% Moatbottom 49% Globalbottom 44% Newsbottom 41% Techbottom 33% Product: 3 distinct product lines · Company stage: Public Funding: Raised $69.5M across 5 rounds · 5 rounds over 20 yrs (0.2/yr) rank vs industry peers · Fliar Intelligence Index 60/100 | $69M | 5 mo ago | 234 | 1991 | — | — | — |
| 14 | Haystack Oncology Provider of personalized cancer diagnostic tests | $67M | 44 mo ago | 45 | 2021 | — | — | — |
| 15 | Gliknik Discovering and developing innovative biologics for immune disorders and cancers 22Funding top 21%Moat top 21%Product top 25%Patents top 31% All 9 signals ▾Fundingtop 21% Moattop 21% Producttop 25% Patentstop 31% Innovationtop 33% Globalbottom 36% Newsbottom 22% Marketbottom 20% Techbottom 16% Funding: Raised $60.3M across 12 rounds · 12 rounds over 16 yrs (0.8/yr) Moat: Editorial + unicorn rating 7/10 · IP moat: 246 patents rank vs industry peers · Fliar Intelligence Index 22/100 | $60M | 10 mo ago | 6 | 2007 | — | 246 patents Engineered multimeric Fc fusion proteins for enhanced complement activation and therapeutic antibodies | — |
| 16 | AsclepiX Therapeutics Developing anti-angiogenic therapeutics | $58M | 35 mo ago | 8 | 2011 | — | — | — |
| 17 | Dracen Developer of thaerapeutics for the treatment of cancers | $57M | 51 mo ago | 8 | 2017 | Thomas Estok CEO & President | — | — |
| 18 | American Gene Developer of lentivirus therapies for the treatment of cancer and other chronic human diseases 55Funding top 24%Patents top 31%Moat top 35%Talent top 35% All 11 signals ▾Fundingtop 24% Patentstop 31% Moattop 35% Talenttop 35% Innovationtop 37% Growthtop 40% Producttop 40% Techtop 46% Marketbottom 36% Globalbottom 36% Newsbottom 22% Funding: Raised $52.8M across 10 rounds · 10 rounds over 13 yrs (0.8/yr) Patents: 228 patents matched (strict assignee match) · 90 filings since 2022 vs 138 in 2017-21 rank vs industry peers · Fliar Intelligence Index 55/100 | $53M | 7 mo ago | 31 | 2008 | Jeff Galvin Chief Executive Officer | 228 patents Non-integrating viral vectors for gene delivery and HIV immunotherapy, plus gamma‑delta T‑cell activation | — |
| 19 | OncoC4 Developer of immunotherapy for cancer patients 62Patents top 17%Innovation top 21%Funding top 28%Moat top 33% All 7 signals ▾Patentstop 17% Innovationtop 21% Fundingtop 28% Moattop 33% Globalbottom 43% Marketbottom 42% Newsbottom 34% Patents: 128 patents matched (strict assignee match) · 115 filings since 2022 vs 13 in 2017-21 Innovation: 128 patents (top 15% of patent-holders) · 115 filings since 2022 vs 13 in 2017-21 rank vs industry peers · Fliar Intelligence Index 62/100 | $52M | 8 mo ago | 41 | 2020 | — | 128 patents Immune checkpoint antibody therapeutics, especially anti‑CTLA‑4 combos for cancer treatment | 1 job opening |
| 20 | Zyngenia Develops monoclonal antibody (mAb)-based drugs to treat cancer, inflammation and autoimmune disorders | $43M | 165 mo ago | 6 | 2008 | Carlos Barbas Founder | 37 patents Engineered multispecific peptide‑antibody complexes targeting EGFR and Ang‑2 for cancer therapy | — |
| 21 | VLP Therapeutics Developer of therapeutic vaccines for the treatment of cancer, infectious and CNS disease | $37M | 34 mo ago | 15 | 2012 | Wataru Akahata Co-Founder & CEO | — | — |
| 22 | NexImmune Developer of immunotherapeutics for cancer | $36M | 87 mo ago | 69 | 2011 | — | 92 patents Patents concentrated in health & consumer products | — |
| 23 | Mana Therapeutics Developer of therapies for the treatment of cancer | $35M | 54 mo ago | 9 | 2017 | Catherine Bollard Co-Founder | — | — |
| 24 | Rapafusyn Developer of therapeutics for treatment of multiple diseses | $28M | 9 mo ago | 3 | 2015 | Sean Hu CEO | — | — |
| 25 | Cellective Therapeutics Biotech research company working on B Cell Research for cancer and autoimmune diseases, acquired by MedImmune… | $28M | 260 mo ago | — | 2003 | Pascal Soriot CEO | — | — |
| 26 | Vaccinogen Exploring video game history, developers, and software providers | $17M | 127 mo ago | 24 24 → 12 (-50%) | 2007 | — | 6 patents Personalized autologous tumor antigen vaccines for cancer immunotherapy | — |
| 27 | Cytimmune Multifunctional and tumor-targeted cancer therapies | $15M | 65 mo ago | 1 | 1988 | Lawrence Tamarkin Co-Founder | — | — |
| 28 | mRNA Developer of therapeutics for the treatment of cancer, rare diseases, and others | $12M | 50 mo ago | 9 | 2016 | Dong Shen CEO | — | — |
| 29 | US Medical Innovations Developer of electrosurgery and plasma technology for the treatment of cancer | $11M | 45 mo ago | 29 | 2010 | — | — | 2 launchs |
| 30 | Benevir Innovative medicine, therapies, and medical technology for global healthcare solutions | $11M | 103 mo ago | 10 | 2011 | — | — | — |
| 31 | VerImmune Developer of vaccines for the treatment of cancer | $10M | 13 mo ago | 7 | 2019 | John Troyer Founder & COO | 36 patents Virus-like particle-based cancer immunotherapies that redirect antigen-specific immune responses | 1 award |
| 32 | Flavocure Biotech Developing next-generation oncology solutions inspired by nature for cancer treatment | $8M | 16 mo ago | — | 2014 | Henry Lowe Co-Founder | — | — |
| 33 | OS Therapies Developer of therapies for treating cancer | $8M | 3 mo ago | 5 | 2017 | Paul Romness CEO | 10 patents Ocular drug delivery formulations and handheld thermal devices for eye surface disorders | — |
| 34 | BioMarker Strategies Develops Cancer Diagnostics System | $7M | 104 mo ago | 8 | 2007 | Jerry Parrott President | 31 patents Predictive biomarkers and assays for enhancing immune checkpoint inhibitor cancer therapy | — |
| 35 | Theranostics Health Personalized medicine through proteomic-based diagnostics and therapeutics for improved healthcare | $7M | 129 mo ago | 5 | 2006 | Luis Gutierrez President & CEO | — | — |
| 36 | miRecule Developing microRNA therapies for the treatment of cancers | $5M | 9 mo ago | 8 | 2018 | Anthony Saleh Co-Founder & CEO | 52 patents Muscle‑targeted imaging agents and nucleic‑acid therapeutics for neuromuscular disorders | 1 award |
| 37 | OncoSTING Developer of immunotherapy for bladder cancer | $5M | 6 mo ago | 3 | 2018 | William Bill Bishai Co-Founder | — | — |
| 38 | Creatv Bio Developer of blood based tests for treating cancer | $4M | 81 mo ago | 9 | 2020 | — | — | — |
| 39 | Ibex Biosciences Developer of antibody and gene therapy technologies for oncology, inflammation, autoimmune disease and… | $4M | 16 mo ago | 11 | 2015 | — | — | — |
| 40 | Cellicure Developer of cell-based immunotherapies for cancer treatment | $4M | 49 mo ago | 3 | 2021 | Q Li Co-Founder & CEO | 6 patents Genetically engineered immune cell therapies (e.g., CAR‑T, modified lymphocytes) | — |
| 41 | Previse Provider of diagnostic tests for the detection of cancer | $3M | 32 mo ago | 10 | 2018 | Dan Lunz Co-Founder & CEO | — | — |
| 42 | Iyuda Therapeutics Developer of medicines for the treatment of multiple conditions | $3M | 3 mo ago | — | 2007 | William Sargent Jr. Founder & Chief Business Officer | — | — |
| 43 | Irazu Oncology Developer of vaccines for colorectal cancer patients | $3M | 30 mo ago | 2 | 2022 | Marco Chacon Founder | 5 patents Engineered Salmonella typhi live bacterial vectors for cancer antigen vaccine delivery. | — |
| 44 | Northwest Biotherapeutics Developer of dendritic cell-based vaccines for prostate and brain cancer | $2M | 18 mo ago | 22 | 1998 | — | 250 patents Dendritic cell-based cancer immunotherapies and checkpoint inhibitor combination treatments. | — |
| 45 | Cage Pharma Developer of drugs targeting the tumor metabolism | $2M | 25 mo ago | — | 2017 | Jeff Geschwind Founder | — | — |
| 46 | A&G Pharmaceutical Theranostics company developing targeted therapeutics and companion diagnostics for personalized cancer care | $2M | 16 mo ago | 12 | 2000 | Ginette Serrero Co - Founder & CEO & Board Director | — | — |
| 47 | Amplexd Therapeutics Developer of therapeutics to treat cervical cancer | $2M | 25 mo ago | — | 2022 | Reid von Borstel Co-Founder | — | — |
| 48 | Nanocan Developer of therapeutic solutions for cancer treatment | $1M | 14 mo ago | 5 | 2020 | Eric Broyles Founder & CEO | — | — |
| 49 | Shuttle Pharma Developer of therapies to improve outcome of radiation therapy in cancer suffering patients | $1M | 12 mo ago | 7 | 2012 | — | — | — |
| 50 | ImmunoBlue Developer of nanoimmunotherapies for cancer treatment using nanotechnology and immunotherapy | $400K | 21 mo ago | — | 2016 | Rohan Fernandes Founder and CEO | — | — |
Top 12 Oncology companies in Maryland
#1
Series B · Baltimore, Maryland · founded 2019 · 197 employees$331.6Mraised▾
Provider of DNA sequencing for cancer detection. The company's platform uses artificial intelligence and whole genome sequencing to detect unique patterns of DNA fragmentation in the blood of patients with cancer.
- Dec 2025Conventional Debt$34.3M
- Jun 2024Series B—
- Jul 2022Series B$225M
- Jan 2021Series A$101.1M
#2
Public · Gaithersburg, Maryland · founded 2007 · 88 employees$267Mraised▾
Developer of RNA-based therapeutics for the treatment of cancer and fibrosis disease. The company has proprietary delivery technologies, a polypeptide nanoparticle RNAi platform and GalNAc RNAi platform, GalAhead, to develop drug candidate pipeline which include STP122G for cardiovascular disease treatment. It also, develops pipeline of drugs for cancers, skin conditions, fibrosis-related diseases, antiviral and cardiometabolic diseases, and medical aesthetics.
- Sep 2025Post IPO$17.7M
- Jul 2021Series E$105M
- Oct 2020Series D$105M
- Jul 2019Series C$25M
#3
Public · Rockville, Maryland · founded 1991 · 234 employees$69.5Mraised▾
Developer of therapeutics for the treatment of cancer. The company's pipeline includes ENMD-2076, a selective angiogenic kinase inhibitor, and 2ME2 for autoimmune disorders. ENMD-2076 has received orphan drug designation from the FDA for the treatment of ovarian cancer, multiple myeloma, acute myeloid leukemia and hepatocellular carcinoma.
- Dec 2025Post IPO$5M
- Jun 2024Post IPO$15M
- Jan 2016Post IPO$10.3M
- Feb 2012Post IPO$10M
#4
Series B · Rockville, Maryland · founded 2008 · 31 employees$52.8Mraised▾
Developer of lentivirus therapies for the treatment of cancer and other chronic human diseases. The company has developed drugs using its delivery platform. The product pipeline includes a liver cancer therapeutic lentivirus and an AIDS therapeutic lentivirus, as well as Parkinson’s disease therapeutic lentivirus, and a familial dysautonomia therapeutic lentivirus.
- Nov 2025Series B$310K
- Apr 2022Series B$50M
- Nov 2015Series A$1.2M
- Sep 2015Grant (prize money)$232.2K
#5
Public · Cambridge, Maryland · founded 2017 · 5 employees$8.4Mraised▾
Developer of therapies for treating cancer. The lead candidate of the company acts on HER-2 a member of the human epidermal growth factor receptor such as HER/EGFR/ERB which is used to treat Osteosarcoma. Also, developing folate receptor-targeted TDC for ovarian, pancreatic, lung, and others.
- Mar 2026Post IPO$2M
- Jan 2026Post IPO$3.5M
- Sep 2025Post IPO$3.8M
- Jun 2025Post IPO$4.2M
#6
Series C · Baltimore, Maryland · founded 2007 · 6 employees$60.3Mraised▾
Discovering and developing innovative biologics for immune disorders and cancers. The company focuses on modulating the immune system to create new treatment options for autoimmune diseases and cancers. They are advancing multiple drugs through clinical trials, including recombinant Fc fusion proteins designed to mimic or inhibit specific immune pathways. Their approach involves a team of talented scientists, board members, scientific advisors, and a network of global thought leaders. They aim to make a significant difference in the lives of individuals with immune disorders through innovative drug discovery and development. Their expertise lies in biologics, clinical trials, drug design, protein production, purification, and analysis, targeting autoimmune diseases and cancers.
- Aug 2025Series C$11M
- Nov 2024Series C$5.3M
- Jul 2023Series C$5.4M
- Jun 2021Series C$11.5M
#7
Series B · Rockville, Maryland · founded 2020 · 41 employees$52.3Mraised▾
Developer of immunotherapy for cancer patients. The lead product, CD24Fc reduces disease progression to death or respiratory failure. The lead candidate ONC-392 is a next-generation anti-CTLA-4 antibody, other candidates targeting cancer cells through chimeric antigen receptors T cells, bi-specific antibodies, and antibody-drug conjugates cells.
- Oct 2025Series B$50M
- Apr 2020Grant (prize money)$2.3M
#8
Series B · Rockville, Maryland · founded 2005 · 51 employees$97.9Mraised▾
Immunomic Therapeutics develops lysosomal-associated membrane protein-based vaccines for the treatment of allergy and cancer. The company has partnered with Astellas to develop vaccines for Japnese red cedar (Phase 1), peanut allergy (Phase 1). Its immunology pipeline includes AST-VAC1 to treat acute myeloid leukemia (AML) (Phase 2); LAMP-Vax + pp64 DC therapy for brain cancer (Phase 1); ATTAC-II clinical trial (Phase II), etc.
- May 2025Series B$6.5M
- Jan 2024Series B$3M
- Jan 2021Series B$77.7M
- Jul 2018Series A$314.5K
#9
Series A · Baltimore, Maryland · founded 2015 · 3 employees$28Mraised▾
Developer of therapeutics for treatment of multiple diseses. It offers platform that screens libraries of hybrid macrocycles to discover lead compound rapafucin-FKBP complexes against novel and validated targets which include oncology, immunosuppression, ischemic reperfusion injury, and neurodegenerative diseases.
- Sep 2025Series A—
- Jun 2024Series A$28M
#10
Seed · Owings Mills, Maryland · founded 2007$2.8Mraised▾
Developer of medicines for the treatment of multiple conditions. The company specializes in research and development focuses on creating cutting-edge therapies to address unmet medical needs such as oncological, infectious, and other immuno diseases.
- Mar 2026Seed$600K
- Oct 2024Seed$1.3M
- Aug 2023Seed$900K
#11
Funding Raised · Baltimore, Maryland · founded 2018 · 3 employees$5Mraised▾
Developer of immunotherapy for bladder cancer. The lead candidate OS-101 is a STING agonist and BCG-based immunotherapy for bladder cancer that trigger proinflammatory innate immune responses against tumors.
- Dec 2025Grant (prize money)$2.2M
- Jun 2024Grant (prize money)$270.2K
- Jun 2022Grant (prize money)$256K
- Sep 2021Grant (prize money)$2.2M
#12
Seed · Rockville, Maryland · founded 2018 · 8 employees$5.5Mraised▾
Developing microRNA therapies for the treatment of cancers. The company's DREAmiR platform utilizes genomic data of patients to identify and develop disease-targeting therapeutics. The product pipeline includes MC-DX4 for Facioscapulohumeral Muscular Dystrophy (FSHD), and MC-30 for Head & Neck Squamous Cell Carcinoma (HNSCC)
- Sep 2025Grant (prize money)$3.1M
- Apr 2025Grant (prize money)$3.1M
- Sep 2024Grant (prize money)$863.7K
- Sep 2021Grant (prize money)$1.9M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Oncology coverage by sub-theme.
Regulatory-risk over time falling
Funding & growth over time
funding rising · growth rising
How research on Oncology in Maryland is moving
A read on the academic research around Oncology in Maryland — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 83 papers.
University of Maryland's cancer institutions dominantly research immune cell function and immunotherapy biomarkers, with an optimistic stance driven overwhelmingly by recent breakthrough and advancement findings.
- University of Maryland, Baltimore56
- University of Maryland, College Park12
- University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center6
- Virginia–Maryland College of Veterinary Medicine5
- University of Maryland, Baltimore County4
- Cancer research1→7
- Immune system4→17
- Tumor microenvironment3→16
- Cancer research1→11
- Immune system2→3
- Tumor microenvironment2→3