Best Orthopedics Companies in Colorado, United States
The 31 best Orthopedics companies in Colorado, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Cerapedics.
Our analysis of 50 Orthopedics companies
$3.4b in tracked funding; 82% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Orthopedics companies in Colorado
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Stage | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Cerapedics Developer of Osteobiologic products | $88M | 100 mo ago | 3 | Valeska Schroeder CEO | DrupalApple iCloud MailMicrosoft 365+22 | Series D | 49 patents Anti-inflammatory coatings for orthopedic implants using peptide-modified calcium phosphate | — |
| 2 | Synergy Spine Solutions Developer of an artificial cervical disc for degenerative disc disease | $30M | 22 mo ago | 10 | Josh Butters CEO | WordPress Block EditorWordPressApple iCloud Mail+23 | Series A | — | — |
| 3 | Point Designs Provider of prosthetic fingers and partial hand prostheses 48Moat top 32%Innovation top 33%Funding top 35%Growth top 35% All 9 signals ▾Moattop 32% Innovationtop 33% Fundingtop 35% Growthtop 35% Patentstop 38% Talenttop 45% Techbottom 40% Globalbottom 31% Marketbottom 22% Moat: Editorial + unicorn rating 4/10 · IP moat: 22 patents Innovation: 22 patents (top 49% of patent-holders) · 17 filings since 2022 vs 5 in 2017-21 rank vs industry peers · Fliar Intelligence Index 48/100 | $27M | 19 mo ago | — | Stephen Huddle Co-Founder | HubSpot CMS HubAmazon Web ServicesHubSpot+11 | Funding Raised | 22 patents Powered prosthetic hand components: thumb/finger actuation, clutch, linkage, and gear systems. | — |
| 4 | Lanx Spinal product portfolio | $16M | 162 mo ago | — | Dan Gladney CEO | — | Acqui-Hired | 254 patents Spinal fixation and orthopedic implant devices for vertebral fusion and stabilization | — |
| 5 | CrossTrees Medical Fabric pod to control flow of bone cement in surgeries for spinal compression fractures | $9M | 204 mo ago | — | Bob Scribner Director | — | Deadpooled | — | — |
| 6 | Xtremity Developer of prosthetic socket systems to restore amputees mobility | $8M | 49 mo ago | 11 | — | — | Acquired | — | — |
| 7 | MuscleSound Point-of-care software for malnutrition assessment and improved patient care 14Moat top 25%Innovation top 46%Patents top 48%Product top 48% All 9 signals ▾Moattop 25% Innovationtop 46% Patentstop 48% Producttop 48% Fundingtop 49% Talentbottom 49% Globalbottom 37% Techbottom 21% Marketbottom 20% Moat: Editorial + unicorn rating 6/10 · IP moat: 34 patents Innovation: 34 patents (top 39% of patent-holders) · 11 filings since 2022 vs 16 in 2017-21 rank vs industry peers · Fliar Intelligence Index 14/100 | $8M | 11 mo ago | 6 | Stephen Kurtz Chairman & CEO | — | Seed | 34 patents Non‑invasive assessment of muscle metabolism, fiber architecture, and fuel status | — |
| 8 | Green Sun Medical Developer of spinal alignment brace to treat conditions like Scoliosis and Kyphosis | $6M | 65 mo ago | 6 | Jamie Haggard CEO and Board Chair | WordPressMySQLPHP+25 | Series A | — | — |
| 9 | Ascendx Spine Surgical device for treating vertebral compression fracture | $6M | 168 mo ago | — | Julian M. Mackenzie Co-Founder & CEO | — | Deadpooled | — | — |
| 10 | Fitbionic Prosthetic foot | $2M | 159 mo ago | — | Jerome Rifkin Founder & ex-CEO | — | Deadpooled | — | — |
| 11 | Aegis Spine Medical device company innovating spine, orthopedics, and minimally invasive technologies | $2M | 60 mo ago | 21 | — | — | Seed | 20 patents Orthopedic spinal fixation implants: adjustable plates and pins for vertebral stabilization. | — |
| 12 | Click Medical Adjustable prosthetic and orthotic solutions for improved fit, comfort, and mobility | $515K | 113 mo ago | 13 | Joe Mahon Co-Founder & CTO | WordPressMySQLPHP+33 | Seed | — | — |
| 13 | Activ Armor Custom 3D printed, waterproof casts and splints for active lifestyles | $300K | 102 mo ago | 3 | — | Cart FunctionalitySquarespace CommerceSquarespace+17 | Seed | — | — |
| 14 | Paragon 28 Provider of foot and ankle surgery devices | $200K | 65 mo ago | 574 | Jim Riegler Co-Founder | WordPressApple iCloud MailMicrosoft 365+35 | Acquired | 856 patents Patient-specific orthopedic surgical guides, fixation plates, and alignment systems for bone surgery | — |
Top 12 Orthopedics companies in Colorado
#1
Seed · Denver, Colorado · founded 2011 · 6 employees$7.5Mraised▾
Point-of-care software for malnutrition assessment and improved patient care. This digital health company offers a clinical decision-support software and ultrasound analytics solution designed to establish a new standard of care for malnutrition. Their patented system automates the analysis of ultrasound images, providing accurate and actionable data to healthcare providers. This cloud-based software platform delivers immediate insights across various healthcare settings, supporting diagnosis, monitoring, and treatment. The technology aims to improve patient outcomes, enhance quality of life, and potentially reduce hospital stays and re-admission rates. It is a point-of-care test to assess malnutrition, enabling high fidelity documentation of malnutrition. The software is utilized by leading medical centers and able to provide a quantitative, non-invasive, rapid response assessment of muscle health.
- Nov 2025Seed$425K
- Apr 2025Seed$650K
- Jan 2025Seed$748.1K
- Aug 2023Seed$236K
#2
Funding Raised · Lafayette, Colorado · founded 2016$26.7Mraised▾
Provider of prosthetic fingers and partial hand prostheses . The flagship product is a prosthesis made from 3D-printed materials for upper limb to improve the quality of life for individuals with partial hand loss.
- Mar 2025Grant (prize money)$6.6M
- Feb 2025Grant (prize money)$6.6M
- Feb 2025Grant (prize money)$1.2M
- Aug 2024Grant (prize money)$1.2M
#3
Series A · Louisville, Colorado · founded 2005 · 10 employees$30Mraised▾
Developer of an artificial cervical disc for degenerative disc disease. The company offers Synergy Disc which is designed to restore physiological motion and correct sagittal balance.
- Dec 2024Series A$406.1K
- Jan 2024Series A$30M
#4
Series D · Westminster, Colorado · founded 1996 · 3 employees$88.5Mraised▾
Cerapedics is an orthobiologics company developing and commercializing its proprietary synthetic small peptide technology platform. i FACTOR Peptide Enhanced Bone Graft is a biologic bone graft that incorporates a small peptide as an attachment factor to stimulate the natural bone healing process. FDAs IDE trial was conducted for i FACTOR in which the product met all the four pre specified primary endpoints investigated in the study.
- Jul 2018Series D$22M
- Apr 2017Conventional Debt$20M
- Sep 2016Series D$11M
- Apr 2015Conventional Debt$4M
#5
Acquired · Denver, Colorado · founded 2001 · 11 employees$7.7Mraised▾
Developer of prosthetic socket systems to restore amputees' mobility. It offers XtremityTTTM Socket System which is injection molded using a proprietary carbon-reinforced polymer.
- Oct 2022Series B—
- Jun 2021Series A$7.7M
#6
Series A · Fort Collins, Colorado · founded 2014 · 6 employees$6.2Mraised▾
Developer of spinal alignment brace to treat conditions like Scoliosis and Kyphosis. The company's brace utilizes the principle of Tissue Remodeling to grow the spine back to a healthier shape. The company's Orthotic seeks to prevent this progression by applying the right forces, as the human body adapts to constant forces with tissue changing shape and length to restore equilibrium. Claims that the company's device is the first orthotic to directly address the complex biomechanics of AIS.
- Jun 2021Series A$1.1M
- Apr 2021Series A$4.6M
- Jan 2020Grant (prize money)$224.9K
- Jan 2018Seed$500K
#7
Acqui-Hired · Broomfield, Colorado · founded 2003$16.1Mraised▾
Lanx was developing and marketing a line of spinal fusion technologies with a focus on minimally invasive and biologics products. Was acquired by Biomet in 2013.
- Apr 2013Series C$15.1M
- Oct 2012Seed$1M
#8
Deadpooled · Boulder, Colorado · founded 2003$9.3Mraised▾
The Crosstrees System by Crosstrees Medical is a new alternative to vertebroplasty and kyphoplasty in the treatment of compression fractures. Its products allow percutaneous vertebral augmentation to control bone cement delivery and decrease cement leakage associated with vertebroplasty and kyphoplasty, the surgical treatments for vertebral compression fractures. The Crosstrees Pod System uses a soft woven fabric pod that allows the physician to control the flow of bone cement as it is injected into the vertebral body. This use of a fabric pod eliminates the balloon inflation step required in traditional kyphoplasty procedures. The Crosstrees Pod system reduces the need for repeated device exchanges during the procedure and therefore is designed to minimize infections.
- Oct 2009Series B$1.3M
- 2008Series B$3.5M
- Feb 2007Series B$4.5M
#9
Deadpooled · Winter Park, Colorado · founded 2011$6.1Mraised▾
Ascendx Spine is a medical device company that manufactures and commercializing orthopaedic devices for treating the spinal disorders. Their product includes Ascendx VCF Repair System for the treatment of a vertebral compression fracture (VCF) caused by osteoporosis. Formerly known as AOI Medical.
- Oct 2012Series A$45K
- May 2012Series A$675K
- Apr 2012Series A$550K
- Aug 2011Series A$4.8M
#10
Seed · Denver, Colorado · founded 2009 · 21 employees$1.6Mraised▾
Medical device company innovating spine, orthopedics, and minimally invasive technologies. Focused on physician-centric solutions, it engineers smarter, safer, and more effective medical products to improve patient outcomes and enhance quality of life. Specializing in functional cervical, thoracolumbar, MIS, SI joint, and DBM solutions, including expandable cages and the CastleLoc Pectus System. They also offer surgical angle measurement tools targeted for improving ease, efficiency and cost-effectiveness in procedures for lumbosacral pedicle screw placements. The company provides intraoperative surgical angle measurement tools, software applications, and related resources for surgical procedures. They also offer distributor opportunities and support.
- Nov 2021Seed$1.6M
#11
Deadpooled · Boulder, Colorado · founded 2006$2.2Mraised▾
Prosthetic foot
#12
Seed · Steamboat Springs, Colorado · founded 2015 · 13 employees$515Kraised▾
Adjustable prosthetic and orthotic solutions for improved fit, comfort, and mobility. They offer innovative, user-adjustable technology for individuals with limb loss and limb difference. Their mission is to empower people to move freely and live fully with prosthetic solutions that adapt to real life. They equip clinicians with tools that deliver a better, more personalized fit, so patients gain comfort and control. Their technology is transforming the O&P field, offering adjustable prosthetic sockets, orthotics, and related products. They provide resources for both individuals/families and O&P providers, including product catalogs, instructions, technical videos, and training. They focus on improving mobility and quality of life through adjustable solutions.
- Jun 2017Seed$405K
- May 2016Seed$110K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Orthopedics coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth flat
What Colorado researches in medical devices
- University of Colorado Anschutz Medical Campus7
- University of Colorado Boulder6
- Colorado State University3
- University of Colorado System2
- Colorado School of Public Health1
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.