Best Orthopedics Companies in England, United Kingdom
The 82 best Orthopedics companies in England, United Kingdom in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Tissue Regenix.
Our analysis of 50 Orthopedics companies
$3.4b in tracked funding; 82% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Orthopedics companies in England
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Tissue Regenix Developer of regenerative medical devices by using cell technology 40Funding top 17%Moat top 38%Patents top 39%Talent top 44% All 10 signals ▾Fundingtop 17% Moattop 38% Patentstop 39% Talenttop 44% Techtop 45% Innovationtop 50% Growthbottom 47% Newsbottom 47% Globalbottom 47% Marketbottom 27% Funding: Raised $128M across 5 rounds · 5 rounds over 11 yrs (0.5/yr) Moat: Editorial + unicorn rating 5/10 · IP moat: 28 patents rank vs industry peers · Fliar Intelligence Index 40/100 | $128M | 5 mo ago | 7 | Steve Couldwell CEO | WordPress Block EditorWordPressMySQL+21 | Top 50M | 28 patents Decellularized tissue scaffolds for regenerative medicine and tissue engineering applications. | — |
| 2 | Alchemab Developer of antibody therapeutics for treating oncology and neurodegenerative conditions 45Funding top 28%Talent top 28%Moat top 31%Growth top 35% All 7 signals ▾Fundingtop 28% Talenttop 28% Moattop 31% Growthtop 35% Globalbottom 37% Marketbottom 34% Techbottom 33% Funding: Raised $82.7M across 3 rounds · 3 rounds over 7 yrs (0.4/yr) Talent: 4 named leaders on record · 4 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 45/100 | $83M | 9 mo ago | 8 | Jane Osbourn Co-Founder & CEO | WordPress Block EditorWordPressMySQL+14 | Top 10M | — | — |
| 3 | ApaTech Synthetic bone repair material | $57M | 216 mo ago | 43 | Philip William Morgan Co-Founder | — | — | 86 patents Porous hydroxyapatite-based biomaterials for medical implant and tissue engineering applications. | — |
| 4 | Levicept Developer of therapeutics for the treatment of chronic pain | $51M | 57 mo ago | 6 | Simon Westbrook CSO and Founder | WordPress Site EditorWordPressMySQL+10 | Top 50M | 105 patents Patents concentrated in chemistry & materials | — |
| 5 | Locate Bio Developer next generation of orthobiologics products for the treatment of injuries | $32M | 27 mo ago | 12 12 → 27 (+125%) · sector median +52% | Kevin Shakesheff Co-Founder | WordPressMySQLPHP+23 | Top 50M | — | — |
| 6 | GripAble Provider of cloud-based rehabilitation device with a companion app for the patients 53Growth top 21%Funding top 32%AI top 45%Talent bottom 49% All 8 signals ▾Growthtop 21% Fundingtop 32% AItop 45% Talentbottom 49% Productbottom 48% Techbottom 45% Globalbottom 37% Marketbottom 27% Growth: Headcount 11 → 27 (+145%) across vintages · Fresh capital in last 24 mo Funding: Raised $16.5M across 6 rounds · 6 rounds over 9 yrs (0.7/yr) rank vs industry peers · Fliar Intelligence Index 53/100 | $17M | 3 mo ago | 27 27 → 17 (-37%) · sector median +52% | Mike Mace CTO - Cofounder | WordPressMySQLSalesforce+22 | Top 50M | — | — |
| 7 | OrthoSon Developer of a medical device for the treatment of chronic back pain | $13M | 49 mo ago | 13 13 → 19 (+46%) · sector median +52% | Rich Simmonds Chief Executive Officer | — | — | 5 patents Modular ultrasound imaging systems and spinal fixation/repair implant technologies. | — |
| 8 | Orthomimetics Resorbable implant for minimally invasive repair of small osteochondral defects | $10M | 234 mo ago | 2 | Andrew Lynn Founder & CEO | — | — | 7 patents Orthopedic arthroscopy tools, elastic bone‑mimicking biomaterials, and implant delivery systems | — |
| 9 | MatOrtho Developer of portfolio of orthopedic implants | $9M | 60 mo ago | 52 | Mike Tuke Founder | HubSpot CMS HubChart.jsIsotope+18 | Top 50M | 117 patents Ceramic femoral resurfacing heads and dual‑mobility acetabular implants for joint replacement | 2 launchs |
| 10 | Open Bionics Manufactures robotic prosthetic hand | $7M | 89 mo ago | 32 32 → 58 (+81%) · sector median +52% | Samantha Payne Co Founder and COO | WordPress Block EditorWordPressMySQL+26 | Top 1M | 33 patents advanced 3D‑printed low‑cost prosthetic hands with sensory feedback | — |
| 11 | Stanmore Implants Modular implants for limb sparing and complex primary and revision joint replacement | $6M | 150 mo ago | 126 | — | — | — | 56 patents Percutaneous orthopedic implant systems for bone fixation and prosthetic integration | — |
| 12 | Eventum Orthopaedics Developer of measurement device for knee replacement operations | $5M | 15 mo ago | 5 | Paul Atherton Co-Founder & COO | WordPress Block EditorElementorWordPress+26 | Top 50M | 19 patents Patella replacement surgical instruments and soft‑tissue mechanical testing devices | — |
| 13 | Touch Bionics Developer of upper-limb prosthetic for the treatment of patients with upper-limb deficiencies | $5M | 176 mo ago | 45 | — | — | — | 133 patents Advanced prosthetic hand components, actuation mechanisms, and sensor-based control systems. | — |
| 14 | Garland Surgical Developer of surgical implants for hip replacement 9Funding bottom 49%Talent bottom 49%Global bottom 36%Market bottom 18% All 4 signals ▾Fundingbottom 49% Talentbottom 49% Globalbottom 36% Marketbottom 18% Funding: Raised $4.1M across 2 rounds · 2 rounds over 1 yrs (2.0/yr) Talent: 1 named leader on record · 1 C-suite/founder profile curated rank vs industry peers · Fliar Intelligence Index 9/100 | $4M | 1 mo ago | 3 | Simon Mifsud Founder & CEO | — | — | — | — |
| 15 | Link Biologics Developer of therapeutics to treat inflammatory and degenerative disorders | $4M | 34 mo ago | — | Tony Day Co-Founder | — | — | — | — |
| 16 | Genrobotics Developer of an AI-based robotic device for mobility management | $3M | 48 mo ago | 124 | Rashid Karimbanakkal Co-Founder | — | Top 50M | — | 1 launch · 1 partnership · 1 expansion |
| 17 | OrthoSolution A range of orthopedic implants and instruments | $2M | 81 mo ago | 28 | Rupert Hosking Co-Founder | Amazon Web ServicesjQueryFlickity+7 | Top 10M | — | — |
| 18 | Biocomposites Developer of synthetic calcium composite products for bone repair and regeneration | $2M | 15 mo ago | 225 | John Joseph Cooper Co-Founder | WordPressMySQLPHP+22 | Top 5M | 71 patents Bioresorbable orthopedic fixation screws and antibiotic‑loaded calcium sulfate bone cements | — |
| 19 | Mesenbio Developer of of therapeutic solutions for arthritis treatment | $2M | 29 mo ago | — | David Kuntin Co-Founder & CEO | Cart FunctionalitySquarespace CommerceSquarespace+10 | Top 50M | — | — |
| 20 | RepRegen Smart biomaterials company | $2M | 187 mo ago | — | Daniel Green Co-Founder | — | — | 8 patents Multicomponent glass additives for personal care product formulations | — |
| 21 | OSSTEC Developer of regenerative orthopedic implants | $1M | 14 mo ago | 3 | Maxwell Munford Founder & CEO | WixSentryBootstrap+11 | Top 50M | 20 patents Design and manufacturing of tibial and orthopedic implant components for joint replacement | — |
| 22 | Koalaa Manufacturer of affordable arm prosthetics products | $1M | 28 mo ago | 12 12 → 26 (+117%) · sector median +52% | Nathan Macabuag Founder | Cart FunctionalityWix eCommerceWix+19 | Top 50M | 6 patents Design and manufacturing of advanced limb prosthetic devices and components. | — |
| 23 | Orthonika Total Meniscus Replacement for the Knee | $1M | 36 mo ago | 7 | Mario Accardi Executive Chairman and Co-Founder | — | — | 4 patents Patents concentrated in health & consumer products | — |
| 24 | Handsome A range of Orthopedic support products | $1M | 84 mo ago | 4 | — | — | — | 10 patents Orthopedic neck/back braces with integrated massage and TENS therapeutic features. | — |
| 25 | Intelligent Orthopaedics Orthopaedic trauma devices for treating and reducing tibial fractures | $971K | 183 mo ago | 4 | Peter Ogrodnik Co-Founder | — | — | 23 patents Orthopedic surgical targeting guides and wire-retention devices for precise implant placement | — |
| 26 | Renovos Provider of regenerative medicine solutions | $915K | 31 mo ago | 4 | Agnieszka Janeczek Co-Founder | — | — | — | — |
| 27 | Loopwheels Manufacturer and supplier of wheelchair wheels | $382K | 45 mo ago | 7 | Sam Pearce Co-Founder | WordPress Site EditorWordPressMySQL+28 | Top 10M | — | 1 partnership |
| 28 | LRE Manufacturer of instruments to restore the normal anatomy of elbow joint in elbow arthritis | $323K | 86 mo ago | 5 | David Laskow-Pooley Founder | — | — | — | — |
Top 12 Orthopedics companies in England
#1
Public · Swillington, England · founded 2006 · 7 employees$127.9Mraised▾
Developer of regenerative medical devices by using cell technology. The company’s patented decellularisation (dCELL) technology removes DNA and other cellular material from the tissue leaving an acellular scaffold and another technology BioRinse provides inductive bone allografts. The product is used for healing chronic wounds, replacing damaged valves, healing damaged joints, and in vascular surgery.
- Dec 2025Post IPO$10.1M
- May 2020Post IPO$15.6M
- Jun 2019Conventional Debt$20M
- Jul 2017Post IPO$51.9M
#2
Series A · London, England · founded 2016 · 27 employees$16.5Mraised▾
Provider of cloud-based rehabilitation device with a companion app for the patients recovering from medical procedures or hospitalization, particularly those affected by stroke. The company has developed a Bluetooth-enabled personal rehabilitation device with a companion app. The app has developed a series of games in which users squeeze the device and loosen their grip to play. It measures grip strength and hand motion to assess and track the patient's cognitive and physical movements over time through a machine learning algorithm.
- Mar 2026Series A$2.7M
- Apr 2022Series A$11M
- Mar 2021Seed$2.2M
- Feb 2019Seed$142.3K
#3
Series A · London, England · founded 2019 · 8 employees$82.7Mraised▾
Developer of antibody therapeutics for treating oncology and neurodegenerative conditions. This organization identifies drug targets by analyzing patient antibody repertoires through deep sequencing and computational analysis. The process focuses on identifying convergent protective antibody responses found in individuals who demonstrate resilience to specific diseases. These findings facilitate the creation of therapeutic candidates intended for clinical application.
- Sep 2025Series A$32M
- Dec 2022Grant (prize money)$2.1M
- 2021Grant (prize money)—
- Apr 2021Series A$82.7M
#4
Seed · Worcester, England · founded 2022 · 3 employees$4.1Mraised▾
Developer of surgical implants for hip replacement. The company designs and develops medical implants including MaltaHip implant possesses a novel interlocking mechanism that engages the various components to minimize the risk of dislocation.
- May 2026Seed$2.4M
- May 2026Grant (prize money)$1.6M
#5
Series B · Ilkley, England · founded 2020 · 5 employees$5Mraised▾
Developer of measurement device for knee replacement operations
- Mar 2025Series B$4.9M
- Mar 2023Series A$3M
- May 2021Seed$2M
#6
Series A · Nottingham, England · founded 2001 · 12 employees$31.6Mraised▾
Developer next generation of orthobiologics products for the treatment of injuries. It offers proprietary and precisely highly engineered tissue scaffolds made of naturally derived materials, to address the repair and regeneration of both bone and cartilage. The products include LDGraft which is an rhBMP-2 product for lumbar interbody fusion procedures. It also has CertOss and OsteoMime in the orthobiologic pipeline.
- Mar 2024Series A$11.8M
- Sep 2021Series A$13.8M
- Jul 2020Seed$2.8M
- May 2019Seed$2.6M
#7
Series A · London, England · founded 2021 · 3 employees$1.5Mraised▾
Developer of regenerative orthopedic implants. The company specializes in bone healing technology and offers partial knee implants that stimulate long-term bone growth.
- Apr 2025Series A$3.2M
- Apr 2023Seed$1.5M
#8
Early Stage · Keele, England · founded 1999 · 225 employees$1.8Mraised▾
Developer of synthetic calcium composite products for bone repair and regeneration. The products include STIMULAN an absorbable calcium sulfate designed to be placed directly at the site of infection in bone and soft tissues. genex ia a synthetic bone graft substitute aimed at supporting natural bone healing, Biosteon is an osteoconductive calcium phosphate composite, Allogran‑R & Bilok used in trauma, spine, and sports injury applications, and NanoBone SBX Putty/QD is a nanostructured hydroxyapatite grafts cleared for interbody spinal fusion.
- Mar 2025Unattributed—
- Mar 2017Unattributed$1.8M
#9
Series B · Sandwich, England · founded 2012 · 6 employees$50.9Mraised▾
Developer of therapeutics for the treatment of chronic pain. The biological therapy LEVI-04 p75NTR-Fc for the treatment of chronic pain delivers neurotrophin homeostasis by providing stable binding proteins for the excess neurotrophins present in chronic pain.
- Sep 2021Series B—
- Nov 2020Series B$22.1M
- Sep 2016Series A$7.9M
- Jun 2015Series A$4.6M
#10
Series A · Oxford, England · founded 2015 · 13 employees$13.3Mraised▾
Developer of a medical device for the treatment of chronic back pain. The device is designed to enable a minimally-invasive, incision-free and motion-preserving alternative to conventionally used highly- invasive spinal fusion procedures.
- May 2022Series A$11M
- Jul 2020Grant (prize money)$324K
- Nov 2019Seed$2.3M
- Jan 2017Seed—
#11
Acquired · Elstree, England · founded 2001 · 43 employees$56.5Mraised▾
ApaTech is an ortho-biologics company, produces synthetic bone repair materials. It offers Actifuse, a synthetic bone graft, which creates a material that promotes the formation of bone and increases the volume of bone formed in the graft/host bone composite structures for small void filling and spinal fusion applications. The company also provides ApaPore, a synthetic and porous hydro-xyapatite grafting for the cemented revision of failed total joint arthroplasties for spinal fusions and fracture fixations, as well as for treating bone defects; and Actifuse MIS Bone Graft Delivery System that offers controlled delivery and precise placement for surgeons performing open and minimally invasive procedures, as well as for use in various spinal and orthopedic procedures, including posterolateral fusion, bone void filling, and acetabular cysts. It offers its products through distributors in Europe and Australia.
- Jun 2008Series B$45M
- Apr 2004Series B$11.5M
#12
Seed · Manchester, England · founded 2020$3.9Mraised▾
Developer of therapeutics to treat inflammatory and degenerative disorders. It offers a lead biologic LinkTSG6 based on TSG-6 protective protein made in all the organs and tissues in response to inflammation and trauma. It is used for the treatment of Dry Eye Disease (DED) and Osteoarthritis.
- Jul 2023Seed$3.9M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Orthopedics coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Medical Devices is moving in the United Kingdom
A read on the academic research around Medical Devices — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 522 United Kingdom-affiliated papers.
- Imperial College London66
- The Medical Device33
- University College London31
- University of Oxford25
- King's College London25
- Surgical robot6→26
- Robot9→24
- Robotic surgery1→4
- Human–computer interaction2→4
- Surgical robot16→30
- Robot14→26
- Biomedical engineering4→12
- Health care2→7
- Robotic surgery8→12
- Surgical robot7→17
- Health care11→17
- Quality (philosophy)3→9
- Robotics5→10
- Product (mathematics)6→11
Where medical devices is researched across United Kingdom
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing medical devices patents in the United Kingdom
United Kingdom medical devices patent filing is accelerating — 44,661 filings from 8,000 assignees (2016–2025), led by Smith & Nephew, Nicoventures Trading, CREO Medical; annual filings 4010→4019.
- Smith & Nephew3022
- Nicoventures Trading1947
- CREO Medical1678
- OWEN Mumford1480
- CMR Surgical1193
- Gyrus Medical1016
- Sanofi Aventis Deutschland1012
- Convatec867
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.