Best Orthopedics Companies in Florida, United States
The 67 best Orthopedics companies in Florida, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: OrthoSensor.
Our analysis of 50 Orthopedics companies
$3.4b in tracked funding; 82% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Orthopedics companies in Florida
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|
| 1 | OrthoSensor Sensor based intelligent orthopedic devices | $123M | 67 mo ago | 92 | — | — | 372 patents Intraoperative orthopedic implant sensing and alignment for joint replacement procedures. | — |
| 2 | Catalyst OrthoScience A total shoulder implant solution 60Funding top 20%Growth top 28%Patents top 28%Product top 31% All 11 signals ▾Fundingtop 20% Growthtop 28% Patentstop 28% Producttop 31% Techtop 32% Moattop 32% Innovationtop 36% Partnerstop 45% Globalbottom 36% Marketbottom 29% Newsbottom 18% Funding: Raised $50.1M across 8 rounds · 8 rounds over 11 yrs (0.7/yr) Growth: Web rank 50,000,000 → 10,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 60/100 | $50M | 8 mo ago | 17 | — | WordPressMySQLPHP+26 | 71 patents Advanced orthopedic joint prostheses and tendon repair devices for surgical fixation | 1 job opening |
| 3 | PainTEQ Innovative SI joint solutions for lasting pain relief and improved stability | $35M | 35 mo ago | 22 | Chris Girsch Co-Founder | WordPressMySQLPHP+21 | — | 1 job opening |
| 4 | Treace Medical Concepts A three-plane Hallux Valgus correction system | $15M | 70 mo ago | 516 516 → 467 (-9%) | — | DrupalPHPAcquia Cloud Platform+32 | 426 patents Patient-specific orthopedic surgical instruments for bone cutting, alignment, and metatarsal correction | 3 launchs |
| 5 | Med-tek Dynamic neuromuscular assessment tool and other soft tissue diagnostic systems | $15M | 135 mo ago | 1 | Kerwin Williams ex-President & CEO | — | — | — |
| 6 | Atlas Spine Innovating minimally invasive spine implants and instruments for improved patient outcomes | $12M | 134 mo ago | 4 | — | — | 112 patents Patents concentrated in health & consumer products | — |
| 7 | Accelus Provider of spine surgery robot systems for healthcare industries 45Talent top 28%Funding top 32%Moat top 39%Growth top 48% All 8 signals ▾Talenttop 28% Fundingtop 32% Moattop 39% Growthtop 48% Techbottom 43% Marketbottom 42% Globalbottom 37% Newsbottom 21% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Funding: Raised $12.0M across 4 rounds · 4 rounds over 4 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 45/100 | $12M | 13 mo ago | 101 | Alex Lukianov Co-Founder & Chairman | WordPressMySQLPHP+25 | — | — |
| 8 | AOI Medical Orthopaedic medical devices for spine and trauma | $6M | 173 mo ago | 1 | Julian M. Mackenzie Chief Executive Officer | — | — | — |
| 9 | Ambulero Developer of cell & gene therapies for the treatment of rare vascular disease and critical limb ischemia | $6M | 36 mo ago | 5 | Robert Buchanan Co-founder | — | — | — |
| 10 | FloSpine Developer of spinal implants and instruments for orthopedic surgeries | $2M | 23 mo ago | 8 | Peter Harris Founder & CEO | — | 39 patents Implantable spinal interspinous/interlaminar and sacroiliac joint stabilization devices | — |
| 11 | BioStem Technologies Provider of placental-based amniotic tissue products | $2M | 31 mo ago | 10 | Andrew VanVurst Co-Founder | WordPress Block EditorWordPressMySQL+29 | 7 patents Regenerative biomaterials from human umbilical cord and placental tissue for therapeutic applications | — |
| 12 | Amend Surgical Developer of ortho-biologics for natural and synthetic bone graft substitutes | $2M | 24 mo ago | 2 | Ron Cobb Co-Founder and Board of Directors | — | — | — |
| 13 | Captiva Spine Developing devices for spinal disorders | $2M | 14 mo ago | 20 20 → 26 (+30%) | Dale Mitchell CEO & Founder | — | — | — |
| 14 | HyperFlex Developer of minimally invasive bunion correction system for mild-to-moderate hallux valgus | $1M | 12 mo ago | — | Bob Peterhans Chief Executive Officer | — | — | — |
| 15 | Adolore Biotherapeutics Developer of non-opioid analgesics for the treatment of pain | $1M | 9 mo ago | — | Joseph Glorioso Founder | — | — | — |
| 16 | SafeWire MIS guide wire technology and pedicle access needles | $1M | 155 mo ago | 9 | Wyatt Geist Founder | — | 3 patents Manufacturing absorbable surgical sutures and related thread-forming technologies. | — |
| 17 | Binder Biomedical Intervertebral Body Fusion System for the spinal disorders | $685K | 169 mo ago | — | Lawrence Binder Founder | — | — | — |
| 18 | Non-Invasive Monitoring Systems Business coaching, consulting, and corporate training for expert business advice | $501K | 146 mo ago | 1 | Jane Hsiao CEO & Chairman | — | — | — |
| 19 | NovaBone Innovating osteobiologics for dental and orthopedic surgeons, fostering natural healing | $291K | 197 mo ago | 36 | — | JoomlaAwesompletePHP+14 | — | 1 launch · 1 partnership |
| 20 | Hip Innovation Technology Orthopedic device solutions provider advancing hip replacement technology and patient care | $225K | 183 mo ago | — | Jim Caruso Co-Founder | — | 218 patents Hip replacement surgical instrumentation and implantation/removal tools for prosthetic components | — |
| 21 | ALPS South Prosthetic liners, sleeves, feet, and skincare solutions for improved mobility | $150K | 153 mo ago | — | Aldo Laghi CEO | WordPress Block EditorWordPressMySQL+24 | 140 patents Advanced prosthetic liner textiles and ankle joint components for enhanced fit and function | 1 launch |
| 22 | TrueMotion Spine Motion preserving spine implants | $122K | 172 mo ago | — | Stephanie Warrington President and Co-Founder | — | — | — |
| 23 | NanoSurgery Technology Corporation Provider of mini-arthroscope | $100K | 111 mo ago | 5 | Mark Walter CEO | — | — | — |
Top 12 Orthopedics companies in Florida
#1
Series E · Naples, Florida · founded 2011 · 17 employees$50.1Mraised▾
Catalyst OrthoScience has developed, Catalyst CSR Shoulder System, a total shoulder implant solution. It is a bone-preserving, less invasive solution indicated for Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-traumatic Arthritis, and Correction of functional deformity. The company has received FDA clearance for it shoulder system.
- Oct 2025Series E$15M
- Oct 2025Conventional Debt—
- Jul 2025Series E$4.1M
- Sep 2024Series E$20M
#2
Series D · Palm Beach Gardens, Florida · founded 2016 · 101 employees$12Mraised▾
Provider of spine surgery robot systems for healthcare industries. Its product portfolio includes fusion robots, lumbar fusion devices, interbody fusion devices, navigation robots, and accessories. Its offering includes targeting tools, semi-automatic positioning, cameras, and workflow management tools.
- May 2025Series D$6.1M
- Jan 2024Conventional Debt$20M
- Jul 2022Series D$12M
- Jul 2021Seed$2.7M
#3
Seed · Delray Beach, Florida · founded 2021$1.3Mraised▾
Developer of non-opioid analgesics for the treatment of pain. The company is focused on the development of gene therapies that are opioid-free anti-pain therapies (DMAPs). The company has two gene therapy product candidates for patients suffering from Erythromelalgia and osteoarthritis knee pain.
- Sep 2025Seed$25K
- Dec 2023Seed$1.1M
- Jan 2022Seed$250K
#4
Seed · Orlando, Florida · founded 2019$1.4Mraised▾
Developer of minimally invasive bunion correction system for mild-to-moderate hallux valgus. The company provides a non-osteotomy solution that gently realigns and stabilizes metatarsal bones, preserving natural foot motion without cutting or drilling bone. The system offers a streamlined surgical workflow with disposable instrumentation, integrating into existing operating room procedures. It allows for earlier treatment of bunions, potentially reducing complications and supporting quicker patient recovery.
- Jun 2025Seed$1.4M
#5
Seed · Jupiter, Florida · founded 2007 · 20 employees$1.5Mraised▾
Captiva Spine is a medical device company focused on developing devices for spinal disorders. Products offered by the company includes pedicle screw system, anterior cervical plate system, lumbar fixation systems, lumbar cages, cervical fixation, cervical cages, bone graft etc.
- Apr 2025Seed$1.5M
#6
Seed · Boca Raton, Florida · founded 2011 · 8 employees$2.2Mraised▾
Developer of spinal implants and instruments for orthopedic surgeries. It offers KeyLift System, Panama cervical plate, Canavaral, Ti-Largo and others for spinal fusion surgeries.
- Jul 2024Seed$1.7M
- May 2023Seed$225K
#7
Funding Raised · Tampa, Florida · founded 2013 · 22 employees$35Mraised▾
Innovative SI joint solutions for lasting pain relief and improved stability. They specialize in minimally invasive procedures for sacroiliac joint dysfunction, offering an alternative to traditional fusion surgery. Their flagship product, LINQ, is a single allograft implant designed to stabilize the SI joint and promote long-term fusion. They provide resources for patients and clinicians, including clinical evidence, educational materials, and support for reimbursement. They focus on improving patients' quality of life by addressing the root cause of SI joint pain, not just masking the symptoms. They offer a less invasive option with faster recovery times, helping patients regain joint stability and return to their daily activities.
- Jul 2023Conventional Debt$35M
#8
Acqui-Hired · Fort Lauderdale, Florida · founded 2006 · 92 employees$122.6Mraised▾
OrthoSensor develops intelligent orthopedic devices and data services that provide quantitative feedback to surgeons and hospitals to assess their patients. Its flagship product Verasense is a disposable sensor-assisted total knee replacement instrument that delivers data wirelessly and enables surgeons to make evidence-based decisions on ligament/soft tissue balance and implant placement in real time.
- Nov 2020Series C$1.5M
- Oct 2020Series C$6.5M
- Oct 2020Conventional Debt$1.3M
- May 2020Series C$6.3M
#9
Acquired · Alachua, Florida · founded 2015 · 2 employees$1.9Mraised▾
Developer of ortho-biologics for natural and synthetic bone graft substitutes. The company's product NanoFuse is a bioactive matrix or bone graft substitute and a bone void filler. It is designed to optimize surgical handling, graft stability and osteoproductivity in orthopedic and spine surgery; It incorporates human demineralized bone matrix (DBM) and synthetic calcium phosphor-silicate particulate material particles (45s5 bioactive glass), both coated with gelatin.
- Jun 2024Series A$1M
- Apr 2017Seed$200K
- Apr 2016Seed$650K
#10
Seed · Miami, Florida · founded 2019 · 5 employees$5.5Mraised▾
Developer of cell & gene therapies for the treatment of rare vascular disease and critical limb ischemia. The company is involved in the development of a regenerative cell that delivers E-selectin adhesion molecules to vascular tissues damaged by disease. Its lead candidate AMB-101 that helps in treating a rare form of vascular disease striking the limbs of young people. It also provides gene therapeutic candidate AMB-202 that delivers E-selectin directly to ischemic tissues and helps in treating critical limb ischemia of diabetic patients.
- Jun 2023Grant (prize money)—
- Jan 2021Seed$5.5M
#11
Public · Pompano Beach, Florida · founded 2006 · 10 employees$2.2Mraised▾
Provider of placental-based amniotic tissue products. Their products contain growth factors, non-aged collagen, Hyaluronic acid, cytokines, extracellular matrix. It has applications in ophthalmology, orthopedic and wound care industries.
- Nov 2023Post IPO$2M
- Apr 2023Post IPO$220K
- Aug 2016Post IPO—
#12
Public · Ponte Vedra Beach, Florida · founded 2013 · 516 employees$15Mraised▾
Treace Medical Concepts is an orthopedic company focused on foot and ankle. Product offering includes Lapiplasty system, a three-plane Hallux Valgus correction system, which is comprised of Control 360 system - a complete sterile-packed instrument and fixation system featuring biplanar plating; Plantar·Python anatomic tension-side plate and Biplanar plating.
- Aug 2020Conventional Debt$50M
- Feb 2019Conventional Debt$20M
- May 2017Series A$5.9M
- Feb 2017Series A$2.1M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Orthopedics coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth flat
What Florida researches in medical devices
- University of South Florida9
- Mayo Clinic in Florida8
- University of Central Florida7
- Florida International University5
- University of Florida4
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.