Best Orthopedics Companies in Italy
The 38 best Orthopedics companies in Italy in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: WISE.
- Orthopedics Market: Rising Burden of Orthopedic Diseases in Developed
Our analysis of 50 Orthopedics companies
$3.4b in tracked funding; 82% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Orthopedics companies in Italy
| # | Company | Last round | Disclosed funding | Stage | Employees | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Citieffe Developer of orthopedic fixation systems | — | — | Acquired | 64 | Fabio Moriggi MD & CEO | WordPressApple iCloud MailGoogle Workspace+30 | — | — |
| 2 | Cizeta Surgical Implantable devices for the treatment of oral-craniomaxillofacial and neurosurgical disorders | — | — | Unfunded | — | Maurizio Marfori Savini CEO & President | PleskPHPNginx+9 | — | — |
| 3 | desmotec Desmotec is an Italian company specialized in the isoinertial training and physical conditioning industry. | — | — | Private | 16 | — | WordPressMySQLPHP+32 | 5 patents Flywheel-based strength training and rehabilitation equipment for sports conditioning | — |
| 4 | Easytech Devices for physiotherapy and rehabilitation | — | — | Acquired | 20 | — | Cart FunctionalityWooCommerceWordPress+27 | — | 1 launch |
| 5 | Electronics Pagani Electromedical devices for Physiotherapy | — | — | Unfunded | — | Roland Pagani Founder | — | — | — |
| 6 | Existo Developer of a rehabilitation device for the upper limb | — | — | Funding Raised | 4 | — | — | — | — |
| 7 | Fisiocomputer Manufacturer and distributor of electro-medical devices intended for physiotherapy and rehabilitation. | — | — | Private | 8 | — | Cart FunctionalityWooCommerceWordPress+31 | — | — |
| 8 | Gloreha Developing robotic glove for rehabilitation | — | — | Unfunded | — | Carlo Seneci Managing Director | WordPressMySQLPHP+24 | — | — |
Top 12 Orthopedics companies in Italy
#1
Series A · Pisa, Tuscany · founded 2014 · 11 employees$2.7Mraised▾
Exoskeletons and robotic rehabilitation devices. The major offerings from the firm are ALEx and Track-Hold. ALEx is a robotic exoskeleton and helps in movement and upper limb rehabilitation. Trackhold is a device for upper limb rehabilitation and passive training with support of gravity in special movements.
- Apr 2026Series A$5.8M
- Apr 2023Seed$2.7M
- Jan 2023Grant (prize money)$278.3K
#2
Series A · Lecce, Apulia · founded 2018 · 34 employees$5.9Mraised▾
Developer of myoelectric prosthesis limb. It uses its propriety technology Bionics to develop prosthetic hand for people with disabilities. The first product is Adam's Hand, a device which is patent-pending and myoelectric and robotic prosthesis it allows users to actuate the five fingers with 15 degrees of freedom and one for each phalanx.
- Jul 2024Series A$5.9M
- Mar 2020Grant (prize money)$55.3K
- Oct 2019Grant (prize money)$54.7K
#3
Series C · Milan, Lombardy · founded 2011 · 40 employees$29.6Mraised▾
WISE is a provider of solutions for neuromodulation and neuromonitoring. It has developed minimally invasive, biocompatible, foldable, and stretchable implantable leads for neuromodulation and neuromonitoring. The foldable nature of their electrodes and wires enables them to be implanted into the area of interest such as spine through a minimally invasive surgery. It provides a flexible electrode that can be folded and introduced into the spinal column using a catheter, thereby allowing it to be used to treat back pain and others. It also provides solutions for mapping of brain activity and pre-surgical epilepsy monitoring. Wise produces their electrodes through a proprietary process called supersonic cluster beam implantation (SCBI) technology, whereby nanoparticles of platinum and iridium are embedded into a silicon-based substrate, creating a composite layer below the surface that becomes an electro-conductive skin.
- Aug 2022Grant (prize money)$50.1K
- Oct 2020Series C$17.6M
- Aug 2019Grant (prize money)$55.1K
- May 2017Series B$7.3M
#4
Series B · Faenza, Emilia Romagna · founded 2014 · 27 employees$26.2Mraised▾
Provider of ortho implants to treat severe fractures and trauma conditions. Their patented technology transforms bamboo into a biomaterial, hydroxyapatite, to provide a bone graft scaffold with high mechanical strength, weight-bearing, and bone regeneration properties needed for large implants. It helps doctors to restore mobility, reduce pain and improve quality of life with a safe, efficacious, and cost-effective solution.
- Oct 2021Grant (prize money)$58K
- Apr 2021Series B$11.9M
- Jun 2017Series A$9.4M
- Sep 2015Series A$3.4M
#5
Series A · Moncalieri, Piedmont · founded 2016 · 47 employees$3.1Mraised▾
Developer of a patient-specific anatomical reconstruction platform designed to offer three-dimensional (3D) anatomical modeling that revolutionizes pre-operative planning. The company's platform offers fidelity three-dimensional (3D) reconstruction of anatomical parts on which delicate surgical operations must be performed, enabling medical professionals to revolutionize and improve preoperative surgical planning.
#6
Series A · Lecce, Apulia · founded 2010 · 50 employees$4.4Mraised▾
Echolight Medical develops a bone densitometer for bone strength assessment at lumbar vertebrae and femoral neck. Products developed by the company include EchoStation (a radiation-free bone densitometry for the early diagnosis of osteoporosis.
- Jul 2021Series A$4.4M
#7
Seed · Milano, Umbria · founded 2012 · 21 employees$1.8Mraised▾
Developer of a disposable sterile device for orthopedic purposes. They have developed a platform, LIPOGEMS, which enables single-step processing of lipoaspirates. It is used to harvest and transfer a patient’s own fat for the repair, reconstruction, and replacement of injured or damaged tissue.
- Jun 2022Seed$1.8M
#8
Series A · Carpi, Emilia Romagna · founded 1980 · 70 employees$3.9Mraised▾
Developer of biomedical therapeutic products designed to treat cancer. The company offers products for orthopedics and oncology treatment are effective and have minimal side effects, enabling healthcare providers improve patients' quality of life by developing and producing and safe therapeutic systems for clinical practice.
#9
Funding Raised · Peccioli, Tuscany · founded 2009$1.8Mraised▾
Prensilia is developing anthropomorphic robotic arms endowed with actuation, sensory and control systems. Their Azurra hand has 5 fingers (similar to a human hand) and weighs just 640 grams. It has 11 DoF and a payload capacity of 4 kilos. It has been envisioned for application as robotic prosthetics, cognitive neuroscience and neural engineering.
- Nov 2020Grant (prize money)$498.4K
- Apr 2020Grant (prize money)$811.9K
- Mar 2016Grant (prize money)$443.5K
#10
Deadpooled · Milan, Lombardy · founded 2003 · 3 employees$4Mraised▾
Provider of biotechnology research and development services designed to develop systems for reconstructive musculoskeletal surgery. The company's pharmaceutical grade services include processing procedures commonly used for musculoskeletal surgery and treatments with bacteriostatic or bactericidal, enabling tissue banks to code, process, preserve, store and distribute human tissues and cells.
#11
Funding Raised · Novara, Piedmont · founded 2016$630.7Kraised▾
Novaicos is developing a therapy for treating bone-loss related diseases. The company has developed a patented only immune-derived active substance for inhibiting bone erosion, prevent osteoporosis and restore the bone structure.
- Jan 2019Grant (prize money)$630.7K
#12
Funding Raised · Rome, Lazio · founded 2014$60Kraised▾
ICan Robotics develops robotic rehabilitation units for people with reduced limb movements or control of the limbs. The upper limb and lower limb rehab units are named Motus and Lenar respectively. The robot is similar to an exoskeleton and replicate the structure of the limbs. The robot is unique, in the sense, it has no joints that have to be accurately aligned with the joints of the patient. This significantly reduces the down time needed for set up of the robot.
- Jul 2019Grant (prize money)$60K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Orthopedics coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Medical Devices is moving in Italy
A read on the academic research around Medical Devices — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 289 Italy-affiliated papers.
- Scuola Superiore Sant'Anna26
- Politecnico di Milano23
- Istituti di Ricovero e Cura a Carattere Scientifico17
- University of Modena and Reggio Emilia16
- Italian Institute of Technology14
- Wireless1→5
- Robotic surgery1→5
- Robotic surgery3→17
- Surgical robot13→25
- Robot10→15
- Biomedical engineering1→5
- Antimicrobial1→4
- Product (mathematics)2→10
- Quality (philosophy)1→8
- Health care1→6
- Surgical robot4→8
- Robotic surgery2→5
Where medical devices is researched across Italy
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.