Best Orthopedics Companies in New York, United States
The 41 best Orthopedics companies in New York, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Companion Spine.
Our analysis of 50 Orthopedics companies
$3.4b in tracked funding; 82% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Orthopedics companies in New York
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Companion Spine Developer of medical devices for spine treatment and therapies | $69M | 34 mo ago | 13 | 2020 | Erick Cloix CEO | WordPressMySQLPHP+30 | — | — |
| 2 | Epibone Developer of patient‑specific bone and cartilage grafts 50Moat top 25%Talent top 28%Funding top 29%Patents top 32% All 9 signals ▾Moattop 25% Talenttop 28% Fundingtop 29% Patentstop 32% Innovationtop 38% Techtop 46% Globalbottom 42% Marketbottom 31% Newsbottom 21% Moat: Editorial + unicorn rating 7/10 · IP moat: 48 patents Talent: 4 named leaders on record · 4 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 50/100 | $44M | 12 mo ago | 34 | 2013 | Elisa Cimetta Co-Founder | Cart FunctionalitySquarespace CommerceSquarespace+12 | 48 patents Regenerative orthopedic biomaterials: injectable off‑the‑shelf cartilage/tendon/ligament scaffolds and decellularized bone matrice | — |
| 3 | AgNovos Healthcare Development of devices for the treatment of osteoporosis | $31M | 38 mo ago | 39 39 → 42 (+8%) | 2012 | James Howe Founder & Chief Medical Officer | Headless UITailwind CSSGatsby+11 | 70 patents Calcium‑phosphate bone graft composites for treating degenerative bone disorders | — |
| 4 | AposHealth Provider of a wellness device for he treatment of musculoskeletal conditions | $28M | 78 mo ago | 75 | 2004 | Amit Mor Co-Founder & Chief Medical Officer | WordPressApple iCloud MailMicrosoft 365+33 | — | — |
| 5 | SOLS Systems 3D printed custom orthotics insoles | $25M | 127 mo ago | 80 | 2013 | — | — | — | — |
| 6 | SpineBioPharma Provider of a non-surgical therapies to treat degenerative spine related diseases | $23M | 23 mo ago | 7 | 2015 | — | JoomlaPHPHelix Ultimate+13 | — | — |
| 7 | BioRestorative Therapies Developer of stem cell therapies to address multiple diseases 27News top 24%Moat top 32%Funding top 33%Patents top 42% All 11 signals ▾Newstop 24% Moattop 32% Fundingtop 33% Patentstop 42% Growthtop 43% Techtop 45% Innovationbottom 48% Globalbottom 41% Talentbottom 40% Fin. healthbottom 26% Marketbottom 21% News: 9 BI events in 12 mo (of 27 tracked, 6 types) · +80% YoY Moat: Editorial + unicorn rating 4/10 · IP moat: 45 patents rank vs industry peers · Fliar Intelligence Index 27/100 | $20M | 10 mo ago | 10 10 → 21 (+110%) | 1997 | Lance Alstodt Chairman and CEO | WordPressMySQLPHP+25 | 45 patents Engineered 3D brown adipose stem cell aggregates for metabolic and regenerative therapies | — |
| 8 | Voom Medical Devices Provider of fusion-free minimally invasive bunion surgery solutions | $15M | 17 mo ago | — | 2017 | Neal Blitz Founder & CEO | SentryReactEmotion+12 | — | 4 launchs |
| 9 | Esper Bionics Provider of AI-based orthopaedic prosthetic and neurology products | $5M | 26 mo ago | 26 | 2019 | Dmytro Gazda Co-Founder & CEO | Framer SitesReactCloudflare+13 | — | — |
| 10 | Regenosine Provides regenerative based therapies for osteoarthritis | $5M | 13 mo ago | 3 | 2018 | Siddhesh Angle CEO | — | — | — |
| 11 | CyberLogic Ultrasound bone densitometer and simulation software for medical and industrial applications | $3M | 144 mo ago | — | 1992 | Jonathan Kaufman CEO | — | 23 patents Ultrasonic bone health assessment and fracture risk evaluation devices | — |
| 12 | ReVivo Medical Developer of spinal implants and surgical devices | $3M | 58 mo ago | 6 | 2011 | Eric Ledet Co-Founder | — | — | — |
| 13 | LegWorks Innovative prosthetic knees empowering amputees with mobility, stability, and confidence | $1M | 94 mo ago | 3 | 2013 | Brandon Burke Co-Founder & Director | Cart FunctionalityShopifyFroala Editor+24 | 2 patents Prosthetic knee joint swing-phase control using variable friction mechanisms | — |
| 14 | BioDynamik Provider of a medical technology company to enhance mobility for individuals with limb loss | $500K | 30 mo ago | — | 2023 | Johnny Chen Founder & CEO | — | 13 patents Medical devices enabling controlled tissue distraction and modular transport mechanisms | — |
| 15 | Unlimited Tomorrow Developer of prosthetics | $500K | 89 mo ago | 23 | 2014 | — | — | 16 patents Advanced prosthetic limb systems with biometric sensing and adaptive grip control | — |
| 16 | Advanced BioMedical Technologies Developer of orthopedic internal fixation devices | $500K | 117 mo ago | 17 | 1984 | — | — | — | — |
| 17 | Azure Biotech Repurposed drugs for women's health | $355K | 139 mo ago | — | 2013 | Valerie Ceva Board Member and Founder | — | — | — |
| 18 | Localized Therapeutics Provider of gene therapy in form of a wearable patch activated with laser light | $223K | 133 mo ago | — | 2012 | Oksana Polesskaya Co-Founder | — | — | — |
Top 12 Orthopedics companies in New York
#1
Series B · Brooklyn, New York · founded 2013 · 34 employees$44.3Mraised▾
Developer of patient‑specific bone and cartilage grafts. The company is offering custom‑shaped, living bone grafts engineered from a patient’s adipose‑derived mesenchymal stem cells and a CT scan of the defect. These are intended for complex bone‑reconstruction cases such as facial, craniofacial, or other skeletal defects.
- Sep 2025Series B$4.3M
- Nov 2024Series B—
- Dec 2022Series B$18.5M
- Nov 2021Series B$1M
#2
Public · Melville, New York · founded 1997 · 10 employees$20.1Mraised▾
Developer of stem cell therapies to address multiple diseases. The company has two core programs, related to the treatment of disc/spine disease and metabolic disorders. The lead cell therapy candidate, BRTX-100, is a product formulated from autologous (or a person’s own) cultured mesenchymal stem cells collected from the patient’s bone marrow and ThermoStem for diabetes.
- Oct 2025Post IPO$1.4M
- Sep 2021Grant (prize money)$255.6K
- May 2016Post IPO$14.4M
- Mar 2014Post IPO$585.8K
#3
Series B · New York City, New York · founded 2017$15.2Mraised▾
Provider of fusion-free minimally invasive bunion surgery solutions. It offer the Bunionplasty® 360 Bunion Repair procedure and Revcon Anchor v2.0 screw for minimally invasive surgery for foot and ankle.
- Apr 2025Series B$5M
- Jul 2024Series B$15.2M
#4
Funding Raised · New York City, New York · founded 2018 · 3 employees$4.5Mraised▾
Regenosine provides regenerative based therapies for osteoarthritis. The company offers its propriety platform for the healing of the purinergic system and maintaining cartilage homeostasis. The company's leading product is regenerating cartilage in joints for osteoarthritis by activating the TGF-beta signaling, with the potential of adenosine for tissue regeneration.
- Jul 2025Grant (prize money)$797.8K
- Jan 2025Grant (prize money)$1.7M
- Aug 2024Grant (prize money)$398.4K
- Sep 2021Grant (prize money)$1.7M
#5
Series C · New York City, New York · founded 2015 · 7 employees$23.4Mraised▾
Provider of non-surgical therapies to treat degenerative spine-related diseases. It provides an alternative of invasive surgeries and opioids that will reduce pain, restore function and slow or stop pathological spinal disease progression without using opioids.
- Sep 2024Series C$13.5M
- Sep 2024Conventional Debt—
- Oct 2023Conventional Debt—
- Oct 2023Series B$2.4M
#6
Series A · New York City, New York · founded 2020 · 13 employees$68.6Mraised▾
Developer of medical devices for spine treatment and therapies. The company develops a portfolio of non-invasive diagnostic and medical implant solutions for the treatment of spine conditions. The products of the company include a "Diam" implant for the treatment of degenerative disc disease and "Aperius" an inntervertebral implant for the percutaneous treatment of Lumbar Stenosis.
- Nov 2023Series A$8.5M
- Feb 2022Series A$60.1M
#7
Series C · New York City, New York · founded 2012 · 39 employees$31.5Mraised▾
AgNovos Healthcare develops medical devices, with a focus on bone health. The company, founded by orthopedic surgeon Dr. James Howe, is developing treatments that have the potential to alter the landscape of bone health. The company aims to reduce the devastating personal and societal costs of bone diseases like osteoporosis. There is no update regarding the product as of May 2017.
- Jun 2023Series C$31.5M
#8
Series A · New York City, New York · founded 2019 · 26 employees$5Mraised▾
Provider of AI-based orthopaedic prosthetic and neurology products. It offers bionic self-learning hand prosthesis and a wearable brain-computer interface. It also provides a cloud-based software solution that individualizes the control of wearables. It has applications in the development of mechatronics, wearable electronics, and natural implants.
- Jun 2024Series A$5M
- Oct 2021Seed—
- Sep 2020Seed—
#9
Series C · New York City, New York · founded 2004 · 75 employees$28.5Mraised▾
Provider of a wellness device for he treatment of musculoskeletal conditions. It offers a non-invasive medical device that is personalized to treat the cause of your specific pain by retraining gait and knee osteoarthritis.
- Feb 2020Series C$11M
- Aug 2016Series B$2.5M
- Dec 2015Venture Debt$5.3M
- Nov 2014Series B$15M
#10
Acqui-Hired · New York City, New York · founded 2013 · 80 employees$25.4Mraised▾
Sols offers custom 3D-printed insoles for consumer and medical applications. Before ordering, patients and practitioners can review and update an interactive model of the product they have created and make prescription and feature changes in real-time. Products can be used for corrective pain relief. Backed by strategic investor ALM (Advanced Laser Materials) of Austin, Texas.
- Feb 2016Series B$4.4M
- Feb 2015Series B$11.1M
- Mar 2014Series A$6.4M
- Jan 2014Series A$1.8M
#11
Seed · New York City, New York · founded 2023$500Kraised▾
Provider of a medical technology company to enhance mobility for individuals with limb loss
#12
Seed · Albany, New York · founded 2011 · 6 employees$2.5Mraised▾
ReVivo Medical is a startup that develops spinal implants and surgical devices that can be used by surgeons, hospitals, and healthcare systems. The products are intended to be used for back, neck, and spine-related pain.
- Oct 2021Seed$2M
- Mar 2021Seed—
- Jan 2021Seed$550K
- Sep 2015Grant (prize money)$224.8K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Orthopedics coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth flat
How research on Medical Devices is moving in the United States
A read on the academic research around Medical Devices — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,830 United States-affiliated papers.
- Johns Hopkins University74
- United States Food and Drug Administration59
- Harvard University54
- Center for Devices and Radiological Health53
- Design Intelligence36
- Biocompatible material2→9
- Robotics7→13
- Health care1→6
- Tissue engineering1→5
- Automation1→5
- Health care2→24
- MEDLINE1→21
- Quality (philosophy)3→15
- Robotic surgery18→29
- Product (mathematics)5→16
- MEDLINE1→36
- Robotic surgery7→24
- Patient safety19→32
- Key (lock)6→19
- Quality (philosophy)10→20
Where medical devices is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing medical devices patents in the United States
United States medical devices patent filing is accelerating — 666,693 filings from 8,000 assignees (2016–2025), led by Covidien, Boston Scient Scimed, Medtronic; annual filings 63466→63610.
- Covidien29348
- Boston Scient Scimed24762
- Medtronic22394
- Becton Dickinson18249
- Procter & Gamble16178
- Ethicon ENDO Surgery13723
- Kimberly Clark12440
- Ethicon11761
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.