Best Orthopedics Companies in Ohio, United States
The 38 best Orthopedics companies in Ohio, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: OrthoHelix Surgical Designs.
Our analysis of 50 Orthopedics companies
$3.4b in tracked funding; 82% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Orthopedics companies in Ohio
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|
| 1 | OrthoHelix Surgical Designs Implants and instruments for small bone reconstructive surgery | $23M | 194 mo ago | 80 | David Kay Founder | — | 50 patents Locking orthopedic fixation plates and surgical guides for small bone and foot repair | — |
| 2 | Lazurite Developer of arthroscopic surgical devices for treating joint problems | $13M | 20 mo ago | 17 17 → 34 (+100%) | Eugene Malinskiy Co-Founder & CPTO | — | 41 patents Wireless medical imaging devices integrating advanced light sources, converters, and battery tech. | 1 job opening |
| 3 | Amplicore Provider of therapeutic solutions for musculoskeletal diseases | $7M | 65 mo ago | 8 | James Lin Founder | — | — | — |
| 4 | Spinal Balance Spinal care innovators reducing infection risk with advanced implant technology | $4M | 76 mo ago | 4 | Anand Agarwal Co-Founder & CEO | — | 38 patents Packaging and sterilization solutions for spinal pedicle screw implants and related devices. | — |
| 5 | Atreon Orthopedics Innovating orthopedics with advanced biologic solutions for musculoskeletal healing | $4M | 47 mo ago | 7 | — | WordPressMySQLPHP+22 | 4 patents Electrospun biodegradable scaffolds for surgical tissue repair with integrated suture management | — |
| 6 | OsteoNovus Provider of biomimetic materials to support and regenerate bone | $4M | 72 mo ago | 9 | Sarit Bhaduri Dfacers Faimbe Fnai Co-Founder and Board Member | — | 7 patents Spherical calcium phosphate granules for bone and dental regeneration applications | — |
| 7 | Intellirod Spine Developer of wireless implantable microelectronic spinal rod strain sensor | $4M | 121 mo ago | 4 | — | — | — | — |
| 8 | Armatus Developer of precision gene therapies for rare diseases | $3M | 16 mo ago | 9 | Scott Harper Co-Founder | WordPressMySQLPHP+19 | — | — |
| 9 | SpineForm Spinal implant designed to help correct and straighten spinal deformities | $3M | 144 mo ago | — | Joe Reynolds CEO | — | 22 patents Spinal fixation implants and delivery tools for minimally invasive orthopedic surgery. | — |
| 10 | Vertebration Spinal implant systems | $2M | 202 mo ago | — | Henry Fabian Co-Founder & CEO | — | 6 patents Spinal surgical instruments and implant deployment systems for vertebral procedures. | — |
| 11 | RSB Spine Spinal fusion products for degenerative disc disease | $2M | 191 mo ago | — | John Redmond CEO | — | 55 patents Spinal fixation plates and related orthopedic implant devices for vertebral stabilization. | — |
| 12 | AMB Surgical Developer of automated growing rod for juvenile and adolescent surgeries | $1M | 82 mo ago | 2 | Tyson Ross Co-Founder | — | — | — |
| 13 | Clear Image Technology Diagnostic scope system to evaluate conditions within the joint | $500K | 169 mo ago | 8 | Elliot Reed ex-CEO | — | — | — |
| 14 | Milo Biotechnology Developer of gene therapies for the treatment of muscular dystrophy | $250K | 118 mo ago | — | Al Hawkins CEO and Founder | — | — | — |
| 15 | Apto Orthopaedics Fixation of spinal deformities in children | $223K | 144 mo ago | — | Steve Fening Co-Founder | — | — | — |
| 16 | Thermedx Endoscopic and fluid management solutions for orthopedic, urological and gynecological procedures | $194K | 139 mo ago | 22 | — | — | 52 patents Medical fluid handling devices: infusion, dialysis, and precise fluid volume control systems. | — |
| 17 | Rekovo Provider of a device for physical rehabilitation | $100K | 143 mo ago | 3 | Todd Whittington Co-Founder & CEO | — | — | — |
Top 12 Orthopedics companies in Ohio
#1
Series A · Cleveland, Ohio · founded 2015 · 17 employees$12.9Mraised▾
Developer of arthroscopic surgical devices for treating joint problems. The company offers a modular ArthroFree wireless camera system for minimally invasive surgery. Also, provides Meridiem light engine for signal transmission, power, and light in ArthroFree.
- Dec 2024Series A$1.7M
- Jun 2021Series A$10M
- Sep 2015Seed$1.3M
#2
Seed · Columbus, Ohio · founded 2020 · 9 employees$3Mraised▾
Developer of precision gene therapies for rare diseases. It offers AAV-based gene replacement therapy candidates which include ARM 101, ARM 102, ARM 201, and ARM 202 for neuromuscular disorders.
- May 2025Seed$3M
#3
Series A · Hilliard, Ohio · founded 2016 · 7 employees$3.8Mraised▾
Innovating orthopedics with advanced biologic solutions for musculoskeletal healing. They are dedicated to advancing healing in sports medicine injuries. They design medical devices using electrospinning technology to produce synthetic nanofiber scaffolds that accelerate and support natural soft tissue regeneration. Their advanced scaffolds create an optimal biologic environment, promoting native tissue regeneration and driving improved long-term outcomes for patients. Their products include bioresorbable wicks and autobiologic matrices designed to improve tissue quality and support the healing cascade after rotator cuff repair and tendon repairs. They focus on addressing biologic healing challenges with innovative solutions, aiming to improve healing and speed of recovery. They offer solutions for rotator cuff repair and soft-tissue augmentation, developed to improve long-term healing across a range of tendon repairs.
- Oct 2022Series A$5.4M
#4
Acquired · Medina, Ohio · founded 2004 · 80 employees$23.3Mraised▾
OrthoHelix is a medical device company developing a range of implants and instruments for use in small bone reconstructive surgery. OrthoHelix’s portfolio is led by its MaxLock Extreme small bone screw and plate systems featuring proprietary anatomic contouring, low profile, and multiplanar fixation. It was acquired by Tornier, a global medical device company in 2012.
- Jun 2010Grant (prize money)$1M
- Apr 2010Series C$14M
- Jun 2009Series C$2M
- May 2008Series C$7.3M
#5
Seed · Cincinnati, Ohio · founded 2018 · 8 employees$6.8Mraised▾
AMPLICORE is a provider of therapeutic solutions for musculoskeletal diseases. It has developed a striking injectable formulation AM1101 that reduces joint osteoarthritis pain, inhibits cartilage degradation, and promotes tissue regeneration of the aberrant cartilage. It provides various products such as AM1101 injectable drug, AM3101 repairing kit, AM2101 for low back pain treatment, and others.
- Mar 2021Seed$4M
- Jan 2020Seed$2.8M
- Grant (prize money)$2M
#6
Series A · Toledo, Ohio · founded 2013 · 4 employees$4.3Mraised▾
Spinal care innovators reducing infection risk with advanced implant technology. They design and develop pioneering technologies in spinal care, focusing on patient safety and improved surgical outcomes. Their team of surgeons and engineers collaborate to create holistic products that offer turnkey solutions to healthcare challenges. A key innovation is their proprietary implant guard, clinically proven to protect implants intraoperatively, reducing contamination. Committed to ethical practices, they prioritize long-term relationships with customers, healthcare professionals, and hospitals. They aim to advance patient care by improving surgical experiences and outcomes while reducing healthcare costs. They offer first-in-class implants and instrumentation that provide real-time clinical benefits for treating spinal diseases.
- Apr 2020Series A$4.3M
- 2013Grant (prize money)$600K
#7
Seed · Toledo, Ohio · founded 2013 · 9 employees$3.6Mraised▾
Provider of biomimetic materials to support and regenerate bone. Its technology encompasses novel synthetic calcium phosphate-based cement that is suitable for several clinical applications, including bone voids, treatment of various fractures and spinal disorders. The product is available in various forms, such as injectable and moldable putty, granules, and structural blocks for orthopedic and spine surgery.
- Sep 2020Seed$1.1M
- Apr 2017Seed$2.5M
#8
Series B · Akron, Ohio · founded 2003 · 4 employees$3.5Mraised▾
Developer of wireless implantable microelectronic spinal rod strain sensor. The company's strain monitoring system will allow spine surgeons to objectively assess the strain on implanted spinal fusion rods and help them monitor post-operative fusion progress. The company currently offers two products i.e. the LoadPro Intraoperative Rod strain sensor, and AccuVista Postoperative Rod strain sensor
- Jul 2016Series B$1M
- Jun 2015Series B—
- Jan 2014Conventional Debt$1.6M
- Mar 2013Series B$1.1M
#9
Deadpooled · Cincinnati, Ohio · founded 2004$2.8Mraised▾
SpineForm is developing minimally invasive surgical treatment spinal correction system that will treat scoliosis (curvature of the spine) in children. They have developed, HemiBridge, a spinal implant designed to help correct and straighten spinal deformities in growing children.
- Sep 2014Conventional Debt$544.6K
- Oct 2013Grant (prize money)$1.6M
- Sep 2012Grant (prize money)$600K
- Mar 2011Seed$1M
#10
Funding Raised · Franklin, Ohio · founded 2016 · 2 employees$1.1Mraised▾
AMB Surgical is developing medical devices for juvenile and adolescent surgeries. The flagship product, FLYTE is a Smart Automated Growing Rod (SAGR) which provide real-time feedback to surgeons allowing the device to automatically grow with the child instead of multiple surgeries. The company focuses on its application for pediatric scoliosis.
- Nov 2019Conventional Debt$418.8K
- May 2019Grant (prize money)$50K
- Nov 2017Conventional Debt$600K
#11
Seed · Columbus, Ohio · founded 2004$1.6Mraised▾
Spinal implant systems
#12
Deadpooled · Cleveland, Ohio · founded 2001$1.5Mraised▾
Spinal fusion products for degenerative disc disease
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Orthopedics coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth flat
How research on Medical Devices is moving in the United States
A read on the academic research around Medical Devices — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 1,830 United States-affiliated papers.
- Johns Hopkins University74
- United States Food and Drug Administration59
- Harvard University54
- Center for Devices and Radiological Health53
- Design Intelligence36
- Biocompatible material2→9
- Robotics7→13
- Health care1→6
- Tissue engineering1→5
- Automation1→5
- Health care2→24
- MEDLINE1→21
- Quality (philosophy)3→15
- Robotic surgery18→29
- Product (mathematics)5→16
- MEDLINE1→36
- Robotic surgery7→24
- Patient safety19→32
- Key (lock)6→19
- Quality (philosophy)10→20
Where medical devices is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Who's filing medical devices patents in the United States
United States medical devices patent filing is accelerating — 666,693 filings from 8,000 assignees (2016–2025), led by Covidien, Boston Scient Scimed, Medtronic; annual filings 63466→63610.
- Covidien29348
- Boston Scient Scimed24762
- Medtronic22394
- Becton Dickinson18249
- Procter & Gamble16178
- Ethicon ENDO Surgery13723
- Kimberly Clark12440
- Ethicon11761