Best Orthopedics Companies in Texas, United States
The 68 best Orthopedics companies in Texas, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Arthrocare.
Our analysis of 50 Orthopedics companies
$3.4b in tracked funding; 82% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Orthopedics companies in Texas
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Arthrocare Products for sports medicine and ENT disorders | $75M | 202 mo ago | 1,840 | 1993 | — | — | 761 patents Knotless soft‑tissue repair devices and electrosurgical systems for orthopedic surgery | — |
| 2 | Innovative Spinal Technologies Minimally invasive treatments for spinal disorders | $63M | 213 mo ago | 10 | 2002 | — | — | 48 patents Spinal fixation and motion-preserving implants for vertebral stabilization and facet fusion | — |
| 3 | Ingeneron Developer of cell-separation technology for regenerative medicine | $51M | 28 mo ago | 30 | 2005 | — | WordPressMySQLPHP+18 | 80 patents Patents concentrated in chemistry & materials | — |
| 4 | Ascension Orthopedics Diagnostics leader transforming data into actionable insights for a healthier future | $49M | 179 mo ago | 12 | 1996 | — | — | 89 patents Orthopedic bone fixation implants and surgical instruments for fracture repair and joint resurfacing | — |
| 5 | Spinal Restoration Minimally invasive therapy for chronic low back pain | $41M | 161 mo ago | 6 | 2004 | Gary Sabins President & CEO | — | 70 patents Regenerative spinal disc therapies and fibrin‑sealant delivery systems for disc repair | — |
| 6 | OsteoCentric Developer of orthopedic medical implants | $32M | 57 mo ago | 64 64 → 73 (+14%) | 2015 | Eric Brown Founder & CEO | — | — | — |
| 7 | Monogram Developer of robotic surgical systems and personalized 3D-printed orthopedic implants | $30M | 52 mo ago | 20 20 → 23 (+15%) | 2016 | Douglas Unis Founder | — | — | — |
| 8 | LDR Developer of products for spinal procedures | $25M | 170 mo ago | 297 | 2000 | David Dvorak CEO & President | — | — | — |
| 9 | Alafair Biosciences Biomaterials and biomedical devices that enhance internal wound healing | $14M | 86 mo ago | 26 | 2011 | — | — | — | 1 launch · 3 awards |
| 10 | Harmonic Bionics Developer of robotic rehabilitation systems designed for upper extremity therapy | $13M | 48 mo ago | 26 | 2016 | — | — | 21 patents Patents concentrated in health & consumer products | — |
| 11 | 4WEB Medical Innovative orthopedic implant company focused on advanced structural design and fusion 40Funding top 39%Growth top 45%Tech top 46%Talent bottom 49% All 8 signals ▾Fundingtop 39% Growthtop 45% Techtop 46% Talentbottom 49% Productbottom 48% Marketbottom 41% Globalbottom 29% Newsbottom 22% Funding: Raised $12.5M across 5 rounds · 5 rounds over 13 yrs (0.4/yr) Growth: Web rank 10,000,000 → 50,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 40/100 | $12M | 14 mo ago | 49 | 2008 | Jessee Hunt Founder & CEO | WordPressApple iCloud MailMySQL+25 | — | 1 internship · 5 launchs |
| 12 | Spinal Stabilization Technologies Spinal medical device company specializing in nucleus replacement technology for back pain | $11M | 16 mo ago | 5 | 2010 | Mark Novotny CEO & President | — | 88 patents Spinal disc replacement implants and related surgical instrumentation for nucleus replacement | — |
| 13 | BioMedical Enterprises Shape memory implant technology for bone fixation | $10M | 204 mo ago | 201 | 1998 | — | — | 15 patents Implantable shape‑memory orthopedic devices and related surgical tools | — |
| 14 | Renovo Concepts Developer of a mechanical tissue resuscitation system for the treatment of traumatic, ischemic, and… | $9M | 38 mo ago | 5 | 2017 | Charles Biltz Co-Founder | — | 9 patents Medical negative-pressure wound therapy devices and biocompatible porous biomaterials. | — |
| 15 | Solenic Medical Developer of non-invasive treatment for infective metallic implant in body | $9M | 27 mo ago | 10 | 2019 | James Lancaster Chief Executive Officer | — | — | — |
| 16 | Gramercy Extremity Orthopedics Portfolio of orthopedic implants and fixation systems | $9M | 75 mo ago | 14 | 2015 | — | — | 25 patents Foot and ankle orthopedic surgical instruments for tarsometatarsal arthrodesis and related supply systems | — |
| 17 | Wenzel Spine Innovative spine technologies improving patient quality of life through simplified surgery | $6M | 55 mo ago | 26 26 → 25 (-4%) | 2008 | — | HubSpot CMS HubEnvoyLazySizes+16 | 28 patents Image-guided spinal surgery tools and expandable intervertebral fusion implants | 1 job opening |
| 18 | Trilliant Surgical Developer of small bone implants for podiatrists and orthopedic surgeons | $6M | 80 mo ago | 57 | 2007 | — | — | 45 patents Advanced orthopedic bone fixation plates and variable-angle locking screw systems | — |
| 19 | IntuiTap Medical A handheld device that enables accurate spinal-needle placement for lumbar punctures | $6M | 59 mo ago | 6 | 2016 | — | — | — | 1 job opening · 4 launchs · 1 partnership |
| 20 | Bone Solutions Provider of ornithological bone void filler bio-materials | $4M | 123 mo ago | 5 | 2004 | — | — | 294 patents Orthopedic fixation implants and bone cement delivery systems for spine, pelvis, and long bones | 1 launch · 1 partnership |
| 21 | Minimus Spine Mobile game developer and distributor with a focus on RPG titles | $4M | 150 mo ago | — | 2006 | — | — | — | — |
| 22 | MedHab Remote patient monitoring and therapeutic devices for improved health and performance | $2M | 95 mo ago | 8 | 2008 | — | — | 33 patents Wearable health monitoring devices for fall detection, gait analysis, and activity tracking | — |
| 23 | Progenerative Medical Innovating reduced pressure therapy for orthopedic surgical wound healing | $2M | 94 mo ago | 4 | 2015 | — | — | — | — |
| 24 | TriFusion 3D Printed Prosthetics | $485K | 120 mo ago | — | 2016 | Brandon Sweeney Co-Founder & CTO | — | — | — |
| 25 | Pinnacle Spine Group Innovating spinal fusion with advanced interbody systems and graft delivery | $250K | 175 mo ago | 5 | 2011 | Zach Sowell CEO | — | 28 patents Spinal intervertebral implants and graft delivery/filling systems for vertebral fusion procedures. | — |
| 26 | Nimbus Radiofrequency tissue ablation technology for the treatment of cross axial spinal pain. | $232K | 174 mo ago | — | 2011 | Robert Wright Founder & Director | — | 16 patents Automotive stability control systems and IoT-based industrial automation networking solutions | — |
Top 12 Orthopedics companies in Texas
#1
Series A · Frisco, Texas · founded 2008 · 49 employees$12.5Mraised▾
Innovative orthopedic implant company focused on advanced structural design and fusion. The company develops innovative orthopedic implants utilizing proprietary Truss Implant Technology to stimulate an osteogenic response and facilitate fusion. They offer a range of FDA-cleared implant systems, including posterior, anterior, cervical, lateral, and lumbar spine solutions. Their truss implants feature an advanced structural design produced with additive manufacturing, designed to actively participate in the fusion process. The company's products aim to optimize patient outcomes through mechanobiology, offering solutions for various spine pathologies and surgical approaches. They focus on providing surgeons with advanced tools for predictable and effective interbody fusion.
- Apr 2025Grant (prize money)$2.2M
- Jun 2019Series A—
- Apr 2017Series A$12.5M
- Nov 2014Grant (prize money)$750K
#2
Series B · San Antonio, Texas · founded 2010 · 5 employees$11.2Mraised▾
Spinal medical device company specializing in nucleus replacement technology for back pain. They focus on the design, development, and manufacturing of spinal medical devices. Their primary offering is a lumbar intervertebral disc nucleus replacement designed to alleviate chronic low back pain associated with degenerative disc disease. The technology aims to recreate physiological motion and redistribute weight-bearing forces within the disc. They are committed to meeting the expectations of patients, customers, and regulatory agencies while maintaining a robust quality management system. Their focus is on providing innovative solutions for spinal stabilization through advanced medical device engineering.
- Jan 2025Series B$16.9M
- Jul 2018Series A$11.2M
#3
Series D · Houston, Texas · founded 2005 · 30 employees$51.4Mraised▾
InGeneron has developed cell-based technologies for healthcare, veterinary and life science research. InGeneron’s advanced cell separation technologies enable preparation of adipose-derived regenerative cells, including stem cells, that have the potential to aid physicians and veterinarians in the treatment of a number of diseases, orthopedic injuries and cosmetic procedures
- Feb 2024Series D$1.7M
- Apr 2019Series D$23M
- Mar 2017Series D$20M
- Dec 2016Series A$2.1M
#4
Series A · College Station, Texas · founded 2019 · 10 employees$9.1Mraised▾
Developer of non-invasive treatment for infective metallic implant in body. The company uses proprietary alternating magnetic fields (AMF) technology for non-invasive treatment that addresses a major complication of various surgeries, such as knee and hip replacements, as well as in trauma related implants such as plates and rods.
- Feb 2024Conventional Debt$3.2M
- Jan 2024Conventional Debt$2.2M
- Jun 2023Series A$5.1M
- Dec 2022Series A$3.7M
#5
Series A · San Antonio, Texas · founded 2017 · 5 employees$9.3Mraised▾
Developer of a mechanical tissue resuscitation system for the treatment of traumatic, ischemic, and hemorrhagic injuries in the brain, heart, and spinal cord. The Mechanical Tissue Resuscitation system (MTR) consists of a disposable sub-atmospheric pressure pump for controlled application of sub-atmospheric pressure for treating traumatic brain injury.
- Apr 2023Series A$7.4M
- May 2022Series A$420.1K
- Jun 2021Series A$6.4M
- May 2020Seed$1.3M
#6
Acquired · Austin, Texas · founded 2016 · 20 employees$29.6Mraised▾
Developer of robotic surgical systems and personalized 3D-printed orthopedic implants. It combines AI-driven robotics, 3D imaging, and custom implants to improve accuracy, reduce surgery time, and follow a razor-blade model—selling hardware with recurring implant revenue. It streamlines clinical workflows to optimize individual workflows and automate implant position and alignment.
- Feb 2022Series C$16M
- Jan 2022Grant (prize money)$256K
- Aug 2021Series B$9M
- Mar 2020Series A$14.6M
#7
Series A · Austin, Texas · founded 2015 · 64 employees$31.7Mraised▾
Developer of orthopedic medical implants. The company has developed a technology called Unifi for designing orthopedic implants. The implants are designed based on the patented thread geometries that enable to interlock into the bones.
- Sep 2021Grant (prize money)$1.3M
- Sep 2021Series A$30M
- Sep 2018Grant (prize money)$225K
- Feb 2016Seed$1.7M
#8
Acquired · Austin, Texas · founded 2016 · 26 employees$12.9Mraised▾
Developer of robotic rehabilitation systems designed for upper extremity therapy. It offers devices intended to facilitate natural and comprehensive arm and shoulder rehabilitation. These systems are designed to increase movement repetitions during therapy sessions. The devices offer a range of motion intended to optimize patient recovery.
- May 2022Series A$3M
- Mar 2021Series A$7.4M
- May 2020Seed$2.5M
- Jan 2018Grant (prize money)$225K
#9
Acquired · Austin, Texas · founded 1996 · 12 employees$49.2Mraised▾
Diagnostics leader transforming data into actionable insights for a healthier future. The company provides vital health information, transforming diagnostic data into action across the healthcare continuum. They offer a wide range of in vitro diagnostics solutions, including immunoassay and molecular testing, serving hospitals, labs, point-of-care settings, and retail markets. Their portfolio includes diagnostic solutions for infectious diseases, cardiac conditions, women's health, and general health. They are committed to enhancing well-being through diagnostic innovation, offering products like rapid lateral-flow tests, molecular testing platforms, and lab management software. The company focuses on delivering real-time, actionable intelligence powered by industry-leading expertise, supporting healthcare providers in delivering optimal patient outcomes. They are dedicated to advancing diagnostic science and care, providing tools for testing, tracking, and disease analysis.
- Jul 2011Series D$18.7M
- Jan 2008Series D$21M
- 2005Series C$5.3M
- Jan 2003Series C$2.7M
#10
Acqui-Hired · Plano, Texas · founded 2002 · 10 employees$63.2Mraised▾
Innovative Spinal Technologies is spin off by the Texas Back Institute. Its a spine technology company, that develops motion preservation and minimally invasive treatments for spinal disorders. Its products include AXIENT Dynamic Fixation system, a pedicle screw-based motion system; PARAMOUNT Lumbar Fusion System, which is engineered for lumbar fusion procedures conducted in a minimally invasive, mini-open, or open fashion; PARAMOUNT MIS Pedicle Screw System for single- and multi-level procedures; PARAMOUNT Open Pedicle Screw System, which is designed to meet the needs of minimally invasive lumbar fusion; and PARAMOUNT VBR, which is designed for a minimally invasive transforaminal approach. It was acquired by Integra LifeSciences Holdings Corporation in 2009.
- Sep 2008Series C$18M
- Aug 2005Series B$39M
- 2003Series A$6.2M
#11
Acquired · Austin, Texas · founded 1993 · 1840 employees$75Mraised▾
Arthrocare was offering products for arthroscopic surgery. Also had products for ENT disorders. Acquired by Smith & Nephew in Feb 2014.
- Aug 2009Conventional Debt$75M
#12
Deadpooled · Austin, Texas · founded 2004 · 6 employees$41Mraised▾
Spinal Restoration was formed to identify and develop early intervention, minimally invasive therapies for the treatment of chronic low back pain. The company’s first product is the Biostat System, a proprietary resorbable biologic compound and delivery system for the treatment of chronic disc pain. The Biostat System is a nonsurgical procedure, which delivers a percutaneous injection of BIOSTAT BIOLOGX® Fibrin Sealant into a painful intervertebral disc where it forms a resorbable tissue repair scaffold and stimulates the normal healing process of the damaged disc tissues responsible for discogenic pain. The treatment specifically targets discogenic pain. In July 2013, the company announced that the success criteria for primary analysis of the Phase III Investigational New Drug (IND) study of the Biostat System were not met.
- Dec 2012Series C$5M
- Feb 2010Series C$20M
- Oct 2007Series B$16M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Orthopedics coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth flat
How research on Medical Devices in Texas is moving
A read on the academic research around Medical Devices in Texas — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 72 papers.
- The University of Texas Southwestern Medical Center15
- Texas A&M University13
- University of North Texas6
- The University of Texas at Austin6
- The University of Texas Health Science Center at Houston5
- Robot1→3
- Biomedical engineering7
- Implant4
- Food and drug administration3
- Kinematics3
- Robot3
- Health care4
- Food and drug administration4
- Robotic surgery3
- Surgical robot3
- Scope (computer science)2
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.