Best Disease Self Management Companies in Belgium
The 55 best Disease Self Management companies in Belgium in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Nyxoah.
Belgium's Disease Self Management sector has 55 tracked companies, $251M in disclosed funding, and zero unicorns — which tells you something honest about where this market actually sits right now.
Nyxoah leads the field at $89M raised, with Indigo close behind at $53M. Those two alone account for more than half the sector's total disclosed capital. Sunrise ($24M) and Nobi ($15M) round out the upper tier, and the remaining companies cluster well below that. The global Disease Self Management market was valued at roughly $4.8B in 2023 and is forecast to reach $16.8B by 2033, a 13.4% CAGR driven by lifestyle-related disease prevalence and expanding digital infrastructure. Belgium's funding pool is modest against that backdrop, but the concentration of capital in a handful of names suggests investors here are betting selectively, not broadly. Data security and privacy obligations under increased digital connectivity add a structural cost that smaller players feel hardest. I'd watch how that regulatory pressure shapes the next funding cycle. So the question isn't whether demand is real — it clearly is — but whether Belgium's mid-tier names can close the gap before the global players do it for them.
- ResearchAndMarkets.com
Our analysis of 50 Disease Self Management companies
$3.0b in tracked funding; 94% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Disease Self Management companies in Belgium
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Nyxoah Provider of a neurostimulation device for obstructive sleep apnea treatments | $89M | 6 mo ago | 11 | Robert Taub Founder & Executive Chairman | DrupalPHPUbuntu+18 | Top 10M | 258 patents Implantable neurostimulation devices for treating obstructive sleep apnea. | 1 partnership · 1 award |
| 2 | Indigo Needle free glucose monitoring technology | $53M | 33 mo ago | 33 33 → 34 (+3%) | Danaë Delbeke CEO | WordPressApple iCloud MailMicrosoft 365+20 | Top 50M | — | — |
| 3 | Sunrise Smart device and app for monitoring and managing sleep data | $24M | 9 mo ago | 12 | Pierre Martinot Co-Founder & CTO | Craft CMSPHPYii+16 | Top 50M | 33 patents Sleep monitoring systems analyzing physiological signals to detect sleep stages and disturbances. | — |
| 4 | Noho System to monitor lymphedema care | $18M | 109 mo ago | 2 | Victor Matia Co-Founder | — | — | — | — |
| 5 | Nobi Provider of a smart lamp for fall detection of elderly people | $15M | 17 mo ago | 12 | Stijn Verrept Co-founder & CTO | BackdropOdooCart Functionality+23 | Top 5M | 6 patents Smart home monitoring and safety system for elderly care | — |
| 6 | FibriCheck Developer of a medical app to detect arrhythmias | $13M | 65 mo ago | 28 28 → 32 (+14%) | Jo Van Der Auwera Co-Founder & Chief Compliance Officer | RubyRuby on RailsEnvoy+18 | Top 10M | — | — |
| 7 | Oncomfort Developer of a digital sedation device for managing pain and anxiety | $12M | 70 mo ago | 4 | Mario Huyghe Co-Founder & CEO | — | — | 39 patents Biomedical monitoring devices measuring consciousness, pain, and anxiety via skin-contact electrodes. | — |
| 8 | Pulsify Medical Developer of an ultrasound-based cardiac health monitoring patch | $7M | 62 mo ago | 5 | Lieven Herbots Co-Founder | — | — | 21 patents Medical diagnostic ultrasound imaging systems and related electronic components | — |
| 9 | Kaspard Provider of wearable elderly monitoring and fall detection devices | $5M | 60 mo ago | 2 | Philippe Kaplan Founder & CEO | HubSpot CMS HubYouTubeHubSpot+11 | Top 50M | — | — |
| 10 | moveUp At home rehabilitation for knee surgery patients | $4M | 34 mo ago | 26 26 → 37 (+42%) | Pierre-Yves Druenne Co-Founder | WebflowLeadfeederLinkedin Insight Tag+20 | Top 10M | — | — |
| 11 | TheraSolve Self-adhesive dermal patch for medication adherence | $3M | 137 mo ago | 2 | Jan De Geest Co-Founder | — | — | 5 patents Wearable skin‑contact communication modules for adhesive medical patches | — |
| 12 | BlooLoc Provider of location tracking solution | $2M | 66 mo ago | 5 | — | BootstrapYouTubeNginx+14 | Top 50M | — | — |
| 13 | Watcherr Provider of medical alert devices for elderly people | $2M | 36 mo ago | 3 | Nikolai Stevens Founder | — | — | — | — |
| 14 | Ectosense Provider of connected solutions for monitoring sleep disorders | $2M | 100 mo ago | 9 | Frederik Massie Co-Founder & CTO | — | — | 55 patents Non‑invasive sleep diagnostics and peripheral arterial tone monitoring devices. | — |
| 15 | Moonbird Provider of smart devices for monitoring heart rate or breathing | $2M | 56 mo ago | 6 | Michael Broes Co-Founder | Cart FunctionalityShopifyBootstrap+38 | Top 5M | 6 patents Respiratory guidance and monitoring devices for patient breathing support | 5 launchs |
| 16 | Koios Care Developer of digital biomarkers and products to detect neurodegenrative diseases | $1M | 13 mo ago | 4 | Konstantinos Kyritsis Co-Founder & CEO | — | — | — | — |
| 17 | BioRICS App for real-time stress monitoring and management | $241K | 78 mo ago | 4 | David Westendorf CEO | — | — | 28 patents Wearable physiological monitoring for infection susceptibility, drowsiness, and stress detection | — |
| 18 | Nuviant Medical Implantable neurostimulation systems for chronic diseases | $143K | 127 mo ago | 11 | — | — | — | — | — |
Top 12 Disease Self Management companies in Belgium
#1
Public · Mont Saint Guibert, Wallonia · founded 2009 · 11 employees$88.7Mraised▾
Provider of a neurostimulation device for obstructive sleep apnea treatments. The company's product BLAST-OSA (BiLAteral Hypoglossal Nerve Stimulation for Treatment of Obstructive Sleep Apnea) is used for treating sleep apnea and calculating ODI (Oxygen Desaturation Index) and AHI (Apnea-Hypopnea Index). Its system consists of an implant and disposable patch, which stimulate the nerves of the tongue to make it move, preventing airway obstruction.
- Dec 2025Post IPO$26.4M
- Apr 2023Post IPO$3M
- Feb 2020Series C$27.3M
- Nov 2018Series B$17M
#2
Series C · Namur, Wallonia · founded 2013 · 12 employees$23.8Mraised▾
Smart device and app for monitoring and managing sleep data. Its device is attached to the chin while sleeping to record the sleep data. The app tracks the data and analyses the patterns to diagnose obstructive sleep apnea and other conditions. It also provides insights to improve the quality of sleep based on the data.
- Sep 2025Series C$29M
- Nov 2023Series B$5.9M
- Mar 2023Series B$17.9M
- Jul 2022Grant (prize money)$2.1M
#3
Series B · Antwerp, Flanders · founded 2018 · 12 employees$14.5Mraised▾
Provider of a smart lamp for fall detection of elderly people. The lamp support caregivers in a residential care center to monitor elder's and resident's fall. The integrated device can monitor blood pressure and offers automated lighting when rising from the bed. The device can continuously measurements of room temperature or air quality. The features include fall prevention, night watch, air quality monitoring, smoke & CO2 detection, and care records for body vitals.
- Jan 2025Series B$36.7M
- Jan 2022Series B$14.5M
#4
Seed · Antwerp, Flanders · founded 2022 · 4 employees$1.2Mraised▾
Developer of digital biomarkers and products to detect neurodegenrative diseases. The company develops digital daily activity biomarkers to interface between providers and patients, with a focus on early detection and disease progression of parkinsons disease.
- Jun 2025Seed$1.2M
- Mar 2023Seed—
#5
Series B · Ghent, Flanders · founded 2016 · 33 employees$52.6Mraised▾
Indigo is developing a needle-free continuous glucose monitoring technology using photonics technologies. Indigo is based in Ghent, Belgium, where it benefits from access to Ghent University and more specifically the Photonics Research Group and the NB-Photonics consortium.
- Oct 2023Grant (prize money)$865.2K
- Jul 2020Series B$44.3M
- Jul 2018Grant (prize money)$2.9M
- Dec 2016Series A$7.3M
#6
Series A · Brussels, Brussels · founded 2015 · 26 employees$4.5Mraised▾
moveUp offers a mobile app for at-home rehabilitation for knee surgery patients. The program has 50 training videos. The program automatically adjusts based on actual physical activity and reported pain level to minimize overtraining. The program also comes with a smart wristband which along with the app can be used to generate a personalized report on movement and activities, painkillers intake, reported pain level, and progress in rehab program.
- Sep 2023Grant (prize money)$1.3M
- May 2021Series A$4.5M
- Aug 2020Grant (prize money)$1.8M
#7
Public · Hasselt, Flanders · founded 2014 · 28 employees$12.6Mraised▾
Developer of a medical app to detect arrhythmias. The app helps patients in detecting cardiac arrhythmia. The app can be used by just placing the finger for 60 seconds on the mobile camera. The app will then utilize the optical light and detector of the mobile device to record the pulse waveform.
- Feb 2021Series B$10.9M
- Oct 2018Grant (prize money)$58K
- Dec 2017Grant (prize money)$23.7K
- May 2017Series A$1.6M
#8
Seed · Aalst, Flanders · founded 2013 · 3 employees$2.2Mraised▾
Provider of medical alert devices for elderly people. It has GPS tracking and fall detection sensors in the devices to get notified for help. Users need to push a button which uses wireless connectivity to signal instantly for help.
- Jul 2023Seed$2.2M
#9
Acquired · Wavre, Wallonia · founded 2017 · 4 employees$11.8Mraised▾
Developer of a digital sedation device for managing pain and anxiety. It has developed an evidence-based anxiety and pain self-management module to improve patients' comfort, using virtual reality. Its modules are non-pharmacological, non-invasive, and safe. The patients receive standardized information on the procedure, surgery, or treatment. Also, the patients are trained in evidence-based stress management techniques. The device is plug and play, portable, and lightweight.
- Sep 2020Series A$11.8M
#10
Series A · Leuven, Flemish Region · founded 2019 · 5 employees$7.4Mraised▾
Developer of an ultrasound-based cardiac health monitoring patch. It tracks cardiac output, stroke volume, and the left ventricle’s ejection to detect insufficient cardiac performance and reduce risks. It continuously measures and monitors cardiac performance. It also has features for data collection, capture, and analysis.
- May 2021Grant (prize money)$2M
- May 2021Series A$4.5M
- Oct 2019Seed$2.9M
#11
Deadpooled · Brussels, Brussels · founded 2015 · 2 employees$17.8Mraised▾
Noho is a system for keeping track of pressure to be applied for lymphedema patients. Consists of a bandage with sensors to measure the pressure applied. The app collects the data and uploads to a global management platform. This data is then compared with the optimum pressure gradient that should be applied in order to reduce the lymphedema.
- Jun 2017Series A$17.8M
#12
Series A · Brussels, Brussels · founded 2017 · 2 employees$4.8Mraised▾
Kaspard has developed a sensor-based device and platform for monitoring the elderly. The company has developed solutions such as a sensor attached to the wall opposite the bed, an app for monitoring the elderly via pictograms and color codes, and a platform to provide the activity reports at end of the day. The sensor detects in case of a fall or when the patient does not return to bed and sends an alert to the nursing staff. The solutions enable the nurses to continuously monitor and manage care for the elderly in bed exits or provide emergency care.
- Jul 2021Series A$3.7M
- 2019Conventional Debt—
- Mar 2019Seed$1.1M
- Feb 2018Conventional Debt$123.6K
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Disease Self Management coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Digital Health is moving in Belgium
A read on the academic research around Digital Health — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 884 Belgium-affiliated papers.
- Triphase340
- KU Leuven118
- Health Information Management68
- Ghent University54
- Ghent University Hospital46
- Health informatics1→8
- Health care2→59
- Public health1→33
- Health informatics3→31
- eHealth1→15
- Telehealth1→9
- Health care8→101
- Public health4→76
- Health informatics14→79
- Nursing research5→43
- MEDLINE3→35
Where digital health is researched across Belgium
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Common questions
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.