Best Disease Self Management Companies in Boston, United States
The 88 best Disease Self Management companies in Boston, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Insulet.
Our analysis of 50 Disease Self Management companies
$3.0b in tracked funding; 94% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Disease Self Management companies in Boston
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | App-install YoY | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Insulet Manufacturer of wearable, tubeless insulin delivery systems for diabetes management | $120M | 144 mo ago | 2,600 2,600 → 5,295 (+104%) | Duane DeSisto Ex-CEO | Apple iCloud MailMicrosoft 365Q4+15 | — | 1,347 patents Closed-loop insulin pump systems with wearable, automated drug delivery and predictive glucose control | — |
| 2 | Buoy Health AI-powered platform for self-diagnosis of medical symptoms | $87M | 67 mo ago | 85 | Andrew Le Co-Founder & CEO | SentryZendeskApple iCloud Mail+23 | — | — | — |
| 3 | Form Health Provider of expert-led personalized nutrition training for weight loss | $61M | 24 mo ago | 22 | Evan Richardson Founder and CEO | WebflowSentryApple iCloud Mail+19 | — | — | 1 job opening · 2 partnerships |
| 4 | Renovia Developer of e-stimulation device and tools for the strengthening of pelvic floor muscles | $57M | 62 mo ago | 19 | Eileen Maus CEO | — | — | 59 patents Patents concentrated in health & consumer products | — |
| 5 | MedRhythms Provider of wearable devices to combat neurological injuries and recover walking functions 80Funding top 19%Growth top 20%Moat top 25%Product top 30% All 12 signals ▾Fundingtop 19% Growthtop 20% Moattop 25% Producttop 30% Innovationtop 33% Patentstop 34% Talenttop 34% AItop 45% Markettop 46% Techbottom 46% Globalbottom 40% Newsbottom 22% Funding: Raised $57.1M across 7 rounds · 7 rounds over 8 yrs (0.9/yr) Growth: Headcount 22 → 41 (+86%) across vintages · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 80/100 | $57M | 4 mo ago | 41 41 → 59 (+44%) | Brian Harris Co-Founder & CEO | — | — | 44 patents Patents concentrated in health & consumer products | — |
| 6 | Figur8 Developer of wearable platform for providing neuromuscular feedback | $52M | 34 mo ago | 24 24 → 26 (+8%) | Nan-Wei Gong Founder CEO | PrismicApple iCloud MailGoogle Workspace+15 | — | 15 patents Wearable sensor-based human motion analysis for medical diagnostics and ergonomic assessment | — |
| 7 | Medisafe Provider of digital medication engagement and adherence platform | $52M | 63 mo ago | 110 | Omri Shor Co-Founder | WordPressSentryApple iCloud Mail+35 | — | — | 1 launch |
| 8 | Sonde Health Provider of a voice-based platform for assessing health conditions | $35M | 42 mo ago | 22 | James Harper Founder and Chief Strategy Officer | Squarespace CommerceSquarespaceTypeScript+24 | — | — | — |
| 9 | Lumia Health Developer of wearable ear devices tracking blood flow to head 64Funding top 28%Growth top 28%Tech top 29%Talent top 38% All 6 signals ▾Fundingtop 28% Growthtop 28% Techtop 29% Talenttop 38% Globalbottom 48% Marketbottom 40% Funding: Raised $29.1M across 3 rounds · 3 rounds over 1 yrs (3.0/yr) Growth: Web rank 10,000,000 → 5,000,000 YoY · Fresh capital in last 24 mo rank vs industry peers · Fliar Intelligence Index 64/100 | $29M | 2 mo ago | — | Paul Jin Co-Founder | TurbopackNode.jsRadix UI+18 | — | — | — |
| 10 | Mightier Gaming platform for the kids to control their emotions | $29M | 54 mo ago | 49 | Trevor Stricker Co-Founder | WordPressMySQLPHP+38 | — | — | — |
| 11 | Ovia Health Provider of mobile application for women's and family health | $23M | 69 mo ago | 80 80 → 89 (+11%) | — | WordPressSentryApple iCloud Mail+19 | — | — | — |
| 12 | RX Cap Provider of smart devices & mobile app for medication management | $20M | 25 mo ago | — | David MacVittie Co-Founder | — | — | — | — |
| 13 | LifePod Provider of AI-powered voice-based virtual caregiver for remote caring of elders | $17M | 72 mo ago | 3 | — | — | — | 18 patents Voice‑activated health monitoring and emergency response systems for user safety | — |
| 14 | EMBR labs Provider of a wearable device for monitoring body temperature | $15M | 20 mo ago | 19 19 → 18 (-5%) | Sam Shames Co-Founder & CRO | Cart FunctionalityShopifySentry+39 | — | 65 patents Wearable thermal management and temperature‑controlled haptic actuation technologies | 1 award |
| 15 | Tal Medical Neurostimulation based treatment for psychiatric disorders | $15M | 134 mo ago | 11 | — | — | — | — | — |
| 16 | Eversound Provider of wireless headphone system designed for senior citizens with hearing loss | $13M | 67 mo ago | 32 | — | — | — | — | — |
| 17 | Kinedu Personalised platform for enabling parent-child interaction | $11M | 36 mo ago | 82 | — | WordPressMySQLPHP+24 | +12% | — | — |
| 18 | Ceras Health Provider of patient adherence and care monitoring devices | $10M | 142 mo ago | 37 | Udaya Devineni CEO | — | — | — | — |
| 19 | Grove Instruments Developer of a non-invasive glucose monitoring device | $9M | 145 mo ago | — | Arthur Combs CEO | — | — | — | — |
| 20 | Backpack Health Personal health record | $8M | 81 mo ago | 16 | — | — | — | — | — |
| 21 | Pact Manufacturer of software and hardware solutions for health & fitness | $7M | 62 mo ago | 13 | Bridget Hunter-Jones Co-Founder & CEO | — | — | — | — |
| 22 | Nix Provider of sweat-based biosensors for monitoring body hydration levels | $6M | 42 mo ago | 33 | — | Cart FunctionalityShopifySentry+33 | — | — | 1 launch · 2 partnerships |
| 23 | STAT Health Provider of in-ear wearable device to detect blood flow abnormalities | $5M | 40 mo ago | 37 | — | — | — | — | — |
| 24 | The Sync Project Music and technology company exploring music's impact on health and wellness | $5M | 109 mo ago | 7 | — | — | — | — | — |
| 25 | BIOMETRY Predictive asthma management through biomarker data and personalized insights 32Moat top 32%Innovation top 33%Patents top 35%Funding top 40% All 6 signals ▾Moattop 32% Innovationtop 33% Patentstop 35% Fundingtop 40% Globalbottom 40% Marketbottom 24% Moat: Editorial + unicorn rating 4/10 · IP moat: 42 patents Innovation: 42 patents (top 29% of patent-holders) · 18 filings since 2022 vs 20 in 2017-21 rank vs industry peers · Fliar Intelligence Index 32/100 | $5M | 6 mo ago | 10 | — | — | — | 42 patents Portable gas chromatography test strips for rapid point‑of‑care chemical analyte detection | — |
| 26 | Vincere Health Provider of a mobile app to manage smoking addiction | $5M | 44 mo ago | 13 | Jacob Keteyian Co-Founder & COO | — | — | — | — |
| 27 | General Prognostics Provider of AI-based health monitoring tools for healthcare professionals | $3M | 19 mo ago | 6 | Javier Echenique Co-Founder & CEO | — | — | — | — |
| 28 | QMedic Provider of a connected wearable for geriatric care | $2M | 152 mo ago | 46 | Sombit Mishra Founder and CEO | Webflow EcommerceWebflowcore-js+15 | — | — | — |
| 29 | EMBioSys Developer of non-invasive wearable technology for induced electric field cancer therapy | $2M | 6 mo ago | — | Vish Subramaniam Co-Founder & CSO | — | — | — | — |
| 30 | Mimo Online VIP slot agent providing trusted, easy-win accounts | $2M | 151 mo ago | 15 | — | Google AdsAdRollcore-js+11 | — | — | — |
| 31 | HBOX Provider of a SaaS-based remote patient monitoring platform and devices for healthcare professionals | $2M | 6 mo ago | 9 | — | WixSentryZoho+13 | — | — | 2 job openings |
| 32 | EyeNexo Provider of a subjective refraction test using a smartphone for vision screening | $2M | 21 mo ago | — | Matteo Tomasi CEO | — | — | — | — |
| 33 | Calibre Provider of wearable device for tracking metabolic rate and respiratory performance | $1M | 51 mo ago | 6 | David Ierardi Chief Executive Officer | Cart FunctionalityShopifySentry+35 | — | 39 patents Portable utility accessories for bicycles, personal items, and novelty packaging solutions | — |
| 34 | Sunsprite Wearable tracker for light exposure to treat neurological disorder by increasing productivity | $1M | 134 mo ago | 5 | Richard Schwartz Co-Founder | — | — | 2 patents Personalized light exposure monitoring for health and therapy applications | — |
| 35 | Lumme Provider of AI-enabled app for tracking calories intake of individuals | $324K | 84 mo ago | 3 | Arun Mathur CEO and Co-Founder | — | — | 4 patents Remote health monitoring platforms integrating wearable sensor data analytics | — |
| 36 | Bitome Wearable device that tracks hydration levels | $225K | 73 mo ago | 607 | — | — | — | 2 patents Miniature in‑vivo NMR biometric sensors for real‑time metabolic monitoring | — |
| 37 | WatchRx AI-powered smartwatch platform transforming healthcare with remote patient monitoring | $121K | 110 mo ago | 8 | Jayanthi Narasimhan Founder & CEO | — | — | 6 patents Digital medication adherence devices integrated with coordinated care platforms | — |
Top 12 Disease Self Management companies in Boston
#1
Series B · Boston, Massachusetts · founded 2013 · 41 employees$57.1Mraised▾
Provider of wearable devices to combat neurological injuries and recover walking functions. The company has developed inertial measurement unit (IMU) sensors to measure gait parameters and run proprietary algorithms on them to make changes to the music accordingly. It uses artificial intelligence to personalize and improve the algorithm over time, as well as make predictive insights about the user population.
- Feb 2026Series B$3.3M
- Mar 2025Series B$2.9M
- Nov 2023Series B$19.8M
- Feb 2023Series B$5.8M
#2
Series B · Boston, Massachusetts · founded 2020$29.1Mraised▾
Developer of wearable ear devices tracking blood flow to head. These devices monitor physiological metrics to assist individuals in understanding how daily activities and physical positioning influence blood circulation. The hardware integrates with mobile software to record and analyze data regarding heart rate and blood flow patterns. Users can tag specific events or behaviors to identify factors that affect their physical state. The system is designed for wellness monitoring and provides information to help users manage their daily habits and physical responses.
- Mar 2026Series B$17M
- Nov 2025Series A$7M
- Nov 2025Grant (prize money)$5.1M
#3
Seed · Boston, Massachusetts · founded 2013 · 10 employees$5Mraised▾
Predictive asthma management through biomarker data and personalized insights. This innovative healthcare company empowers patients to proactively manage their asthma. They leverage patented sensor technology to measure airway inflammation via breath analysis, determining attack risk, medication adherence, and environmental trigger impact. Their app integrates clinical and environmental factors to identify symptom root causes, while their prediction engine builds personalized risk models. Actionable insights are delivered, enabling patients to lower attack risk and improve control. The company proactively engages patients with guideline-based coaching and education, promoting self-management at scale through CDC-recognized programs. This technology-driven approach reimagines asthma care, offering a data-driven, personalized solution for improved patient outcomes. This is a B2C healthcare solution.
- Dec 2025Seed$2.2M
- Aug 2024Seed$5M
#4
Seed · Boston, Massachusetts · founded 2020 · 9 employees$1.7Mraised▾
Provider of a SaaS-based remote patient monitoring platform and devices for healthcare professionals. The company has developed a digital platform that allows healthcare providers to monitor patient health vitals remotely. It has a solution for patient education, patient enrolment, has a patient dashboard system for tracking health, and more. The company delivers medical devices to patients for the monitoring of their health parameters.
- Dec 2025Seed—
- Aug 2022Seed$1M
- Aug 2022Conventional Debt—
- Apr 2022Seed$700K
#5
Funding Raised · Boston, Massachusetts · founded 2022$1.8Mraised▾
Developer of non-invasive wearable technology for induced electric field cancer therapy. The company focuses on creating electrode-free garments designed to inhibit solid cancer metastasis. It aims to improve patient quality of life and standard treatment outcomes. The technology is currently being developed for hard-to-treat solid cancers. Clinical trials are planned to evaluate the therapy's effectiveness.
- Nov 2025Grant (prize money)$1.4M
- Oct 2024Grant (prize money)$211.1K
- Jun 2024Grant (prize money)$211.1K
#6
Series B · Boston, Massachusetts · founded 2014 · 19 employees$15Mraised▾
Provider of a wearable device for monitoring body temperature. The device offers cooling and warming sensations through a wristband. It utilizes thermal waves to stimulate temperature sensitive nerves. The device is designed to provide relief for thermal discomfort. The related mobile application allows users to personalize the experience. The device is worn on the wrist, which is an area of blood flow, and cools or warms the body at a rate of about 0.4 degrees Celsius per second. The prototype consists of a copper alloy based heat sink and a system to control thermal impulses.
- Oct 2024Series B$3M
- May 2023Conventional Debt$35M
- Oct 2021Series B$6M
- Dec 2020Series B—
#7
Series B · Boston, Massachusetts · founded 2019 · 22 employees$60.9Mraised▾
Provider of expert-led personalized nutrition training for weight loss. The platform provides clinically validated weight loss solutions from nutritionists and dieticians. Regular consultation from experts with nutrition plans and results tracking is provided.
- Jun 2024Series B$43M
- Apr 2021Series A$22.9M
#8
Seed · Boston, Massachusetts · founded 2020 · 6 employees$3.2Mraised▾
Provider of AI-based health monitoring tools for healthcare professionals. The company has developed a biomarker-based remote monitoring solution for cardio-renal disease. It has featured blood analysis, remote monitoring analysis, and presymptomatic detection of critical patient conditions.
- Nov 2024Seed—
- Jun 2024Conventional Debt$200K
- Sep 2022Seed$3.2M
- Apr 2021Grant (prize money)$25K
#9
Series A · Boston, Massachusetts · founded 2017 · 24 employees$52.2Mraised▾
Developer of wearable platform for providing neuromuscular feedback. The company has developed the first musculoskeletal diagnostics decision support system that can accurately pinpoint the source and severity of an injury while showing real-time recovery visibility to improve musculoskeletal health at every point of care.
- Aug 2023Series A$25M
- Jun 2021Series A$12M
- Nov 2020Series A$6.2M
- Feb 2020Seed$1.5M
#10
Series A · Boston, Massachusetts · founded 2013$19.7Mraised▾
RxCap is a provider of smart devices & mobile app for medication management. It provides cap specs device that allows a complete solution for patient adherence management. Features include LED light, temperature sensor, rechargeable USB, child safety lock, NFC (optional), Bluetooth, and others.
- Apr 2024Series A$19.7M
#11
Funding Raised · Boston, Massachusetts · founded 2014$1.7Mraised▾
Provider of a subjective refraction test using a smartphone for vision screening. It offers an application that uses Tumbling E letters to assess spherical equivalents and grating patterns to measure astigmatism to support broader vision screening efforts in regions with limited access to eye care.
- Sep 2024Grant (prize money)$245.1K
- Sep 2018Grant (prize money)$254.8K
- Sep 2015Grant (prize money)$1.2M
#12
Series C · Boston, Massachusetts · founded 2014 · 85 employees$86.7Mraised▾
Buoy Health offers an AI based digital health platform that helps the user to self-diagnose medical symptoms. Users are required to provide personal information, symptoms, and other relevant information on medical history. Based on the information provided, the platform provides the most probable diagnosis.
- Nov 2020Series C$37.5M
- Jan 2020Series B$20M
- Aug 2019Series B$20M
- Aug 2017Series A$6.7M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Disease Self Management coverage by sub-theme.
Regulatory-risk over time falling
Funding & growth over time
funding flat · growth flat
How research on Digital Health in Boston is moving
A read on the academic research around Digital Health in Boston — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 224 papers.
Boston University, Boston Children's Hospital, and Boston Medical Center dominate digital health research, primarily examining concern-driven health policy and EHR implementation, with a cautiously mixed but slightly optimistic tone.
- Boston University128
- Boston Children\'s Hospital59
- Boston Medical Center15
- VA Boston Healthcare System13
- University of Massachusetts Boston13
- Health informatics2→6
- Health informatics4→16
- Health care2→13
- Psychological intervention1→9
- Health administration3→9
- Public health1→7
- Health care5→21
- Health informatics13→24
- Public health5→16
- Health administration6→15
- Nursing research4→10
Common questions
Rohit lives in the feed. He covers what's moving right now — the funding rounds, launches and shifts breaking across the trade press — and ties them back to where the sector is heading.