Radar · Disease Self Management in San Francisco
Best Disease Self Management Companies in San Francisco, United States
The 298 best Disease Self Management companies in San Francisco, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Jawbone.
By Riya SenguptaFinancials
298companies tracked
$4.1Bdisclosed funding
4unicorns
145have raised
FLIAR INTELLIGENCE · DISEASE SELF MANAGEMENT × SAN FRANCISCO
Our analysis of 50 Disease Self Management companies
$3.0b in tracked funding; 94% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
50companies analysed
94%cloud-native stacks
2025funding peak (by rounds)
3unicorns
2014median founding year
750kcombined LinkedIn audience
77%of audience held by top 3
4companies hiring publicly (12 mo)
Ranked: Best Disease Self Management companies in San Francisco
| # | Company | Disclosed funding | Last round | Employees | Founded | Founder | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|
| 1 | Jawbone 🦄 Provider of wearable devices for activity and sleep tracking | $877M | 125 mo ago | 50 | 1997 | — | — | — |
| 2 | Virta 🦄 Provider of therapies for metabolic health in chronic disease patients | $402M | 62 mo ago | 443 443 → 902 (+104%) | 2014 | Jeff Volek Co-Founder & Chief Science Officer | 3 patents Cable‑suspended ground transport and overland conveyor systems for material handling | — |
| 3 | Livongo Provider of smart devices for diabetes management for patients and doctors | $237M | 72 mo ago | 163 | 2014 | — | — | — |
| 4 | Calm 🦄 Digital wellness platform | $225M | 63 mo ago | 394 394 → 726 (+84%) | 2012 | Michael Smith Co-Founder and Co-Executive Chairman | — | — |
| 5 | Ginger 🦄 On demand mental health solutions for individuals and organizations | $220M | 62 mo ago | 176 | 2011 | Andy Puddicombe Co-Founder | 57 patents AI-driven mental health modeling and secure digital health data encryption platforms. | — |
| 6 | Element Science Wearable therapeutic device for treating sudden cardiac arrest | $193M | 75 mo ago | 74 | 2013 | Uday Kumar Founder | — | 1 job opening · 1 launch |
| 7 | Care Zone Simplifying medication management and healthcare access through technology and pharmacy services | $150M | 96 mo ago | 22 | 2010 | — | — | — |
| 8 | BigHealth CBT therapy for insomnia patients 69Tech top 14%Funding top 23%Moat top 31%News top 36% All 11 signals ▾Techtop 14% Fundingtop 23% Moattop 31% Newstop 36% Markettop 37% Talenttop 38% Producttop 40% Growthtop 44% Fin. healthtop 44% Globalbottom 45% Customersbottom 1% Tech: 62 technologies across 7/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 Funding: Raised $129M across 5 rounds · 5 rounds over 12 yrs (0.4/yr) rank vs industry peers · Fliar Intelligence Index 69/100 | $129M | 4 mo ago | 251 251 → 156 (-38%) | 2010 | Colin Espie Co-Founder | — | 1 partnership |
| 9 | Woebot Health Developer of chat-based AI wellness tools for mental health support | $114M | 51 mo ago | 130 | 2017 | Aaron Beaudette Director Of Product | — | — |
| 10 | iRhythm Tech Provider of cloud-based cardiac rhythm monitoring devices | $109M | 144 mo ago | 1,657 1,657 → 1,872 (+13%) | 2006 | — | — | — |
| 11 | Openwater Provider of imaging technologies for medical diagnosis and treatments | $100M | 21 mo ago | — | 2016 | Mary Lou Jepsen Founder & CEO | — | — |
| 12 | Picnic Medical record management app for patients suffering from chronic disease | $100M | 47 mo ago | 113 113 → 276 (+144%) | 2014 | Troy Astorino Co-Founder and CTO | — | 1 launch |
| 13 | Lumosity Developer of web and app-based games for brain training | $67M | 108 mo ago | 52 | 2005 | — | — | — |
| 14 | Profusa Biochemical sensors for chronic disease management | $62M | 94 mo ago | 15 | 2009 | Ben Hwang Chairman and CEO | 185 patents Near‑IR optical glucose monitoring and tissue‑integrated biosensor technologies. | — |
| 15 | SafelyYou Provider of AI-based solutions for senior care and fall management 64Product top 25%Funding top 26%Tech top 26%AI top 30% All 12 signals ▾Producttop 25% Fundingtop 26% Techtop 26% AItop 30% Moattop 35% Innovationtop 44% Growthtop 47% Patentstop 49% Talentbottom 49% Marketbottom 45% Globalbottom 39% Newsbottom 18% Product: 8 distinct product lines · Company stage: Series C Funding: Raised $59.5M across 6 rounds · 6 rounds over 9 yrs (0.7/yr) rank vs industry peers · Fliar Intelligence Index 64/100 | $60M | 16 mo ago | 85 85 → 191 (+125%) | 2014 | George Netscher Co-Founder & CEO | 4 patents Remote monitoring and communication system for cognitive care event management | — |
| 16 | Hello Sleep behaviour tracking | $51M | 132 mo ago | 46 | 2013 | — | 164 patents Magnetically‑coupled, silicone‑based wearable health sensors for activity and biometric monitoring | — |
| 17 | Spire Health Developer of continuous health monitoring wearable device | $48M | 59 mo ago | 40 | 2014 | — | — | — |
| 18 | Halo Online platform offering wearable brain cortex stimulator to improve exercise performance | $45M | 97 mo ago | 28 | 2013 | — | — | — |
| 19 | Kinsa Provider of thermometer and mobile-based application for tracking the symptoms of fever | $43M | 113 mo ago | 73 | 2012 | Edo Segal Co-Founder | 49 patents Digital health monitoring and fever detection for illness surveillance and outbreak tracking | — |
| 20 | Wildflower Health App to identify high risk pregnancies & assistance | $41M | 18 mo ago | 73 | 2012 | Leah Sparks CEO & Founder | — | — |
| 21 | Signos Provider of a wearable device for blood glucose pattern monitoring 42Tech top 20%Funding top 25%Moat top 39%Customers top 44% All 10 signals ▾Techtop 20% Fundingtop 25% Moattop 39% Customerstop 44% Producttop 46% Talentbottom 49% Marketbottom 40% Globalbottom 36% Growthbottom 31% Newsbottom 22% Tech: 52 technologies across 6/8 capability areas · Cloud: Amazon Cloudfront, Amazon Web Services Funding: Raised $37.0M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) rank vs industry peers · Fliar Intelligence Index 42/100 | $37M | 0 mo ago | 30 | 2020 | Sharam Fouladgar-Mercer Co-Founder & CEO | — | — |
| 22 | Blue Note Therapeutics Digital therapeutics for pre and post cancer related distress symptoms | $31M | 57 mo ago | 43 | 2018 | Geoffrey Eich CEO | — | — |
| 23 | Siren Provides smart socks for preventing diabetic foot ulcers 42Talent top 28%Funding top 29%Growth top 35%Product top 46% All 7 signals ▾Talenttop 28% Fundingtop 29% Growthtop 35% Producttop 46% Techbottom 45% Globalbottom 39% Marketbottom 25% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Funding: Raised $30.9M across 8 rounds · 8 rounds over 11 yrs (0.7/yr) rank vs industry peers · Fliar Intelligence Index 42/100 | $31M | 17 mo ago | 22 | 2015 | Henk Scholten Co-Founder & COO | — | — |
| 24 | Feel Therapeutics Provider of digital Precision Medicine company leveraging objective data and passive measurement for mental… 27Funding top 31%Talent top 38%Product bottom 48%Global bottom 39% All 6 signals ▾Fundingtop 31% Talenttop 38% Productbottom 48% Globalbottom 39% Techbottom 37% Marketbottom 31% Funding: Raised $30.0M across 6 rounds · 6 rounds over 10 yrs (0.6/yr) Talent: 2 named leaders on record · 2 C-suite/founder profiles curated rank vs industry peers · Fliar Intelligence Index 27/100 | $30M | 23 mo ago | 34 | 2015 | George Eleftheriou Co-Founder & CEO | — | — |
| 25 | 100Plus personalized health prediction mobile app | $29M | 63 mo ago | 1,176 | 2011 | Janet Dillione CEO | — | — |
| 26 | January AI-powered precision health platform delivering personalized insights and recommendations | $28M | 46 mo ago | 31 | 2017 | Justin Sonnenburg Co-Founder | 31 patents Patents concentrated in computing, sensing & instrumentation | — |
| 27 | Qardio Manufacturer of digital health devices for remote patient monitoring systems | $27M | 73 mo ago | 17 | 2012 | — | 35 patents Wearable blood‑pressure monitoring cuffs with contextual biometric recording and secure IoT communication | — |
| 28 | Aluna Provider of smart devices for asthma management | $27M | 40 mo ago | 24 | 2020 | Inderjit Jutla Co-Founder & CTO | — | — |
| 29 | Kiddo Health Connected care platform capturing health data of children health for professionals | $25M | 53 mo ago | 4 | 2016 | Jaganath Swamy Co-Founder | — | — |
| 30 | Sano Intelligence Provider of blood sugar monitoring wearable device | $24M | 101 mo ago | 13 | 2011 | Raj Gokal Co-Founder | 31 patents Wearable continuous biosensor devices for real-time body chemistry monitoring | — |
| 31 | Ria Health Offers personalized medical treatment to control alcohol consumption | $18M | 15 mo ago | 33 33 → 82 (+148%) | 2013 | John Mendelson Co-Founder & CMO | — | — |
| 32 | HumanFirst Remote monitoring platform for healthcare professionals | $15M | 60 mo ago | 15 | 2017 | Andy Coravos Co-Founder & CEO | — | — |
| 33 | Sunnyside Provider of a mobile app for monitoring alcohol drinking habits | $15M | 31 mo ago | 25 | 2019 | Nick Allen Co-Founder & CEO | 12 patents Patents concentrated in chemistry & materials | — |
| 34 | Aulisa Developer of wearable wireless vital signs monitoring medical devices | $13M | 53 mo ago | 7 | 2010 | — | — | 4 launchs |
| 35 | BrainHQ Online brain training platform for cognitive improvement and brain health 45Funding top 34%Tech top 36%Talent top 38%Growth top 47% All 9 signals ▾Fundingtop 34% Techtop 36% Talenttop 38% Growthtop 47% Moattop 48% Productbottom 48% Marketbottom 38% Customersbottom 38% Globalbottom 32% Funding: Raised $11.8M across 9 rounds · 9 rounds over 17 yrs (0.5/yr) Tech: 43 technologies across 5/8 capability areas · Cloud: Amazon S3, Amazon Ses rank vs industry peers · Fliar Intelligence Index 45/100 | $12M | 10 mo ago | 31 | 2002 | Michael Merzenich Co-Founder & CSO | — | — |
| 36 | Bone Health Technologies Provider of a wearable device to treat osteopaths and prevent osteoporosis | $8M | 39 mo ago | 10 | 2018 | Daniel Burnett Founder & CEO | — | — |
| 37 | Miro Health AI-powered platform transforming neuropsychological assessment and patient management | $8M | 44 mo ago | 12 | 2013 | Shenly Glenn CEO | — | — |
| 38 | Urban Health Provider of an application for anxiety and sleep management | $7M | 46 mo ago | 21 | 2018 | Rishabh Sahu Co-Founder | — | — |
| 39 | Level Zero Health Developer of biosensor technology for continuous hormone monitoring | $7M | 15 mo ago | — | 2023 | Irene Jia Co-Founder & CTO | — | — |
| 40 | Better Therapeutics AI-based cardiac health treatment & therapy planning software for healthcare professionals | $7M | 29 mo ago | 54 | 2015 | David Perry Chairman and Co-Founder | — | — |
| 41 | Delfina AI-assisted software for monitoring pregnancy and infants' health | $6M | 13 mo ago | 30 | 1995 | Eliza Nguyen Md Mph Co-Founder | — | 2 job openings · 2 partnerships |
| 42 | Biotricity Developer of medical remote monitoring solutions that help prevent and manage chronic diseases | $5M | 26 mo ago | 55 | 2014 | Waqaas Al-Siddiq Co-Founder & CEO | 2 patents Wearable cardiac monitoring devices integrating touch-sensitive electrode displays | — |
| 43 | kegg Manufacturer of medical devices for tracking cervical mucus fertility metrics | $4M | 17 mo ago | 6 | 2017 | Kristina Cahojova Founder & CEO | — | 1 expansion |
| 44 | RCE Provider of smart device to monitor cardiac health | $3M | 30 mo ago | 12 | 2018 | Atandra Burman Founder & CEO | — | — |
| 45 | Amira Provider of smart devices to track menopause symptoms | $3M | 34 mo ago | 8 | 2020 | Felipe Radovitzky Co-Founder & COO | — | — |
| 46 | DUSQ Developer of sleep science studying recovery regulation under modern conditions 29Talent top 28%Funding bottom 47%Tech bottom 47%Global bottom 45% All 5 signals ▾Talenttop 28% Fundingbottom 47% Techbottom 47% Globalbottom 45% Marketbottom 31% Talent: 3 named leaders on record · 3 C-suite/founder profiles curated Funding: Raised $2.6M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) rank vs industry peers · Fliar Intelligence Index 29/100 | $3M | 4 mo ago | — | 2024 | Siddhant Bhargava Co-Founder & CEO | — | — |
| 47 | Roga Provider of a device and appliaction to manage stress | $1M | 23 mo ago | — | 2021 | Alison Smith Co-Founder | — | — |
| 48 | Toi Labs Developer of lower digestive and urinary flow monitoring device | $599K | 17 mo ago | 20 | 2015 | — | 31 patents AI-driven personal health monitoring devices integrated into bathroom environments | — |
| 49 | Mentia AI-powered solutions enhancing dementia care through technology and innovative engagement | $506K | 11 mo ago | 8 | 2017 | Serge Soudoplatoff Cofounder & CTO | — | 1 launch |
| 50 | iSono Health Provider of AI-based 3D wearable device for early breast cancer detection | $120K | 8 mo ago | 10 | 2014 | Neda Razavi CEO | — | — |
Top 12 Disease Self Management companies in San Francisco
#1
Series C · San Francisco, California · founded 2010 · 251 employees$129.3Mraised▾
Series C · San Francisco, California · founded 2010 · 251 employees
CBT therapy for insomnia patients. Its flagship product Sleepio is a digital sleep improvement program, clinically proven to help users overcome poor sleep. Its virtual sleep expert "The Prof" teaches users proven Cognitive Behavioral Therapy (CBT) techniques, personalized to their problems and monitors their progress. Sleepio has been validated in the world’s first placebo-controlled RCT for a digital sleep intervention.
Fliar Intelligence Index™ 69how this company ranks against its industry peers
Tech
top 14%Funding
top 23%Moat
top 31%News
top 36%Market
top 37%Talent
top 38%Tech: 62 technologies across 7/8 capability areas · Cloud: Amazon Cloudfront, Amazon S3 · Devops: Nginx, Varnish
Funding: Raised $129M across 5 rounds · 5 rounds over 12 yrs (0.4/yr) · Last round Series C (Feb 2026)
Moat: Editorial + unicorn rating 8/10 · Soonicorn · 10 curated direct competitors tracked
Audience (LinkedIn): 34k LinkedIn followers — 4.5% of this cohort's audience
Activity (LinkedIn): 1 partnerships (incl. Xealth) announced in 12 mo
Funding rounds
- Feb 2026Series C$23.7M
- Jan 2022Series C$75M
- Jun 2020Series B$39M
- Jul 2016Series B$12M
Founders & team
Investors
Octopus Ventures, Kaiser Permanente Ventures, Index Ventures, JamJar Investments, Samsung NEXT, 5Y Capital
Tech stack
Amazon CloudfrontAmazon S3Amazon SesAmazon Web ServicesApolloApple Icloud Mail
#2
Series B · San Francisco, California · founded 2020 · 30 employees$37Mraised▾
Series B · San Francisco, California · founded 2020 · 30 employees
Provider of a wearable device for blood glucose pattern monitoring. The company has developed an app-based platform that recommends meals and exercises for users based on the glucose pattern detected through the connected device. The app provides real-time glucose monitoring and glucose spike levels for different foods. Based on this, personalized fitness and nutrition plan can be developed.
Fliar Intelligence Index™ 42how this company ranks against its industry peers
Tech
top 20%Funding
top 25%Moat
top 39%Customers
top 44%Product
top 46%Talent
bottom 49%Tech: 52 technologies across 6/8 capability areas · Cloud: Amazon Cloudfront, Amazon Web Services · Devops: Envoy
Funding: Raised $37.0M across 3 rounds · 3 rounds over 5 yrs (0.6/yr) · Last round Series B (May 2026)
Moat: Editorial + unicorn rating 7/10 · 9 curated direct competitors tracked
Audience (LinkedIn): 9k LinkedIn followers
Funding rounds
- Oct 2023Series B$20M
- Nov 2021Series A$13M
- Jan 2021Seed$4M
Founders & team
Investors
Cheyenne Ventures, Google Ventures, Dexcom Ventures, Samsung NEXT, Courtside Ventures, 1984 Ventures
Tech stack
AddshoppersAmazon CloudfrontAmazon Web ServicesCloudflareCloudflare Bot ManagementCore-Js
#3
Series C · San Francisco, California · founded 2014 · 85 employees$59.5Mraised▾
Series C · San Francisco, California · founded 2014 · 85 employees
Provider of AI-based solutions for senior care and fall management. It offers a device and platform designed to improve safety, wellness, and staffing within senior living communities. It delivers tools for fall detection, care activity measurement, and predictive analysis. The platform integrates with existing systems to provide insights and support care delivery.
Fliar Intelligence Index™ 64how this company ranks against its industry peers
Product
top 25%Funding
top 26%Tech
top 26%AI
top 30%Moat
top 35%Innovation
top 44%Product: 8 distinct product lines · Company stage: Series C
Funding: Raised $59.5M across 6 rounds · 6 rounds over 9 yrs (0.7/yr) · Last round Series C (Jan 2025)
Tech: 52 technologies across 6/8 capability areas · Cloud: Amazon Ses, Amazon Web Services · Devops: Varnish
Audience (LinkedIn): 26k LinkedIn followers — 3.5% of this cohort's audience
Funding rounds
- Jan 2025Series C$43M
- May 2023Venture Debt$30M
- Dec 2021Series B$40M
- Sep 2021Series A$19.5M
Founders & team
Investors
Omega Healthcare Investors, Scan-Group, Foundation Capital, Founders Fund, DCVC, Eclipse
Tech stack
All In One SeoAmazon SesAmazon Web ServicesAnimate.CssApple Icloud MailAppnexus
#4
Series A · San Francisco, California · founded 2002 · 31 employees$11.8Mraised▾
Series A · San Francisco, California · founded 2002 · 31 employees
Online brain training platform for cognitive improvement and brain health. It offers specialized online exercises targeting memory, attention, brain speed, people skills, decision-making, and navigation. The platform is built on brain science and neuroplasticity research, adapting to individual user needs with personalized training. It features a personal trainer to track performance and tailor exercises. The platform is accessible on computers and mobile devices, offering flexible training schedules with training reminders. It includes online exercises, progress tracking, and community features. Research supports the cognitive benefits of the exercises. It is used in libraries, insurance programs, sports organizations, educational facilities, and military centers. It offers subscription based access and also has free exercises. It also has login and signup options. It provides resources like blogs, newsletters and support.
Fliar Intelligence Index™ 45how this company ranks against its industry peers
Funding
top 34%Tech
top 36%Talent
top 38%Growth
top 47%Moat
top 48%Product
bottom 48%Funding: Raised $11.8M across 9 rounds · 9 rounds over 17 yrs (0.5/yr) · Last round Grant (prize money) (Jul 2025)
Tech: 43 technologies across 5/8 capability areas · Cloud: Amazon S3, Amazon Ses · Devops: Envoy, Nginx
Talent: 2 named leaders on record · 2 C-suite/founder profiles curated
Funding rounds
- Jul 2025Grant (prize money)$1M
- Dec 2013Grant (prize money)$10.2M
- Aug 2011Grant (prize money)$686K
- Apr 2011Series A$955.4K
Founders & team
Investors
HHS, Military Health
Tech stack
Amazon S3Amazon SesAmazon Web ServicesApple Icloud MailBackbone.JsClicky
#5
Seed · San Francisco, California · founded 2024$2.6Mraised▾
Seed · San Francisco, California · founded 2024
Developer of sleep science studying recovery regulation under modern conditions. It studies neuroscience, autonomic physiology, and evolutionary biology to understand sleep as a system. The company focuses on why recovery fails despite proper sleep habits. It addresses brain body desynchrony, where neural activity, autonomic regulation, and environmental cues are uncoordinated. The company aims to improve recovery capacity and system stability.
Fliar Intelligence Index™ 29how this company ranks against its industry peers
Talent
top 28%Funding
bottom 47%Tech
bottom 47%Global
bottom 45%Market
bottom 31%Talent: 3 named leaders on record · 3 C-suite/founder profiles curated
Funding: Raised $2.6M across 1 rounds · 1 rounds over 1 yrs (1.0/yr) · Last round Seed (Feb 2026)
Tech: 20 technologies across 4/8 capability areas · Cloud: Cloudflare · Observability: Microsoft Clarity, Sentry
Funding rounds
- Feb 2026Seed$2.6M
Founders & team
Investors
Fireside Ventures, Antler, Climber Capital, Startup Sherpas, Vaibhav Investments
Tech stack
Cart FunctionalityCdnjsCloudflareCloudflare Bot ManagementCore-JsFacebook Pixel
#6
Series D · San Francisco, California · founded 2012 · 73 employees$40.8Mraised▾
Series D · San Francisco, California · founded 2012 · 73 employees
Wildflower Health is a provider of health engagement platform to improve health care quality and lower medical costs for pregnant women. Its mobile maternity program, Due Date Plus, uses self-reported data to identify high-risk pregnancies. It helps women manage their health during pregnancy, including directing women to programs available under their health benefits. They recently partnered with LifeMap to launch an app called LifeMap Due Date Plus for expectant parents with short-trm disability coverage.
Funding rounds
- Nov 2024Series D$17.9M
- Mar 2022Series D$26M
- Mar 2018Series C$8M
- Jun 2015Series B$5M
Founders & team
Investors
Triple Tree, Health Enterprise Partners, Hatteras Venture Partners, Echo Health Ventures, Allumia Ventures, Easton Capital Investment Group
Tech stack
Apple Icloud MailBluehostBootstrapCloudflareCloudflare Bot ManagementGoogle Analytics
#7
Series B · San Francisco, California · founded 2015 · 22 employees$30.9Mraised▾
Series B · San Francisco, California · founded 2015 · 22 employees
Sirencare provides smart socks for preventing diabetic foot ulcers. The sock is embedded with a sensor that tracks foot temperature and issues related to inflammation. It comes with a companion app, that sends notifications to the user & doctor on signs of inflammation. To ensure accuracy, the user receives a new shipment of socks to replace the current supply every six months.
Fliar Intelligence Index™ 42how this company ranks against its industry peers
Talent
top 28%Funding
top 29%Growth
top 35%Product
top 46%Tech
bottom 45%Global
bottom 39%Talent: 3 named leaders on record · 3 C-suite/founder profiles curated
Funding: Raised $30.9M across 8 rounds · 8 rounds over 11 yrs (0.7/yr) · Last round Series B (Jan 2025)
Growth: Fresh capital in last 24 mo
Audience (LinkedIn): 4k LinkedIn followers
Funding rounds
- Jan 2025Series B$9.5M
- Sep 2020Series B$9M
- May 2020Series B$11.8M
- 2018Series A$6.5M
Founders & team
Investors
Manta Ray Ventures, Mighty Capital, Portfolia, Khosla Ventures, DCM Ventures, Founders Fund
Tech stack
CloudflareCookiebotGoogle AnalyticsGoogle Font ApiGoogle Hosted LibrariesGoogle Workspace
#8
Series C · San Francisco, California · founded 2016$100Mraised▾
Series C · San Francisco, California · founded 2016
Provider of imaging technologies for medical diagnosis and treatments. It offers a wearable therapeutic and diagnostic headset which is capable of treating cancer, mental disease and measuring cerebral blood flow.
Funding rounds
- Aug 2024Series C$54M
Founders & team
Investors
Plum Alley Investments, Khosla Ventures, Bold Capital Partners, Lauder Partners, Excel Venture Management, Starlight Ventures
Tech stack
Animate.CssCloudflareCloudflare Bot ManagementCore-JsGoogle AnalyticsGoogle Tag Manager
#9
Series A · San Francisco, California · founded 2013 · 33 employees$18.2Mraised▾
Series A · San Francisco, California · founded 2013 · 33 employees
DxRx Medical offers personalized medical treatment to control alcohol consumption. The patient initially consults a specialist physician to get a personalized treatment plan. The treatment program includes medication to control alcohol craving, a smartphone connectable breathalyzer, and a smartphone app. The patient regularly inputs his alcohol levels into the app using the breathalyzer to track his alcohol levels. The at-home treatment program avoids the stigma associated with rehab or in-patient care treatment
LinkedIn Pulse recent public activity · Jul 2026
Audience: 7k LinkedIn followers
Hiring: 3 hiring posts in 12 mo (public) · hiring: Credentialing and Licensing Manager (Hybrid), Billing Specialist
Funding rounds
- Mar 2025Series A—
- Jun 2022Series A$18M
- Oct 2016Seed$250K
Founders & team
Investors
SV Health Investors, BPEA, SOSV, Peloton Equity, IndieBio
Tech stack
Amazon CloudfrontAmazon S3Amazon Web ServicesApple Icloud MailBootstrapCalltrackingmetrics
#10
Early Stage · San Francisco, California · founded 1995 · 30 employees$6.5Mraised▾
Early Stage · San Francisco, California · founded 1995 · 30 employees
AI-assisted software for monitoring pregnancy and infants' health. It offers software that enables parents and their families to track and monitor the health of the fetus and pregnant mother. Also, it helps physicians with patient and workflow management. It provides real-time analysis of baby heart activity for healthcare providers.
LinkedIn Pulse recent public activity · Jul 2026
Audience: 8k LinkedIn followers
Hiring: 4 hiring posts in 12 mo (public) · momentum +2 · hiring: Medical Billing Associate, Bilingual Registered Dietitian
Activity: 3 partnerships (incl. National Association of Community Health Centers (NACHC)) announced in 12 mo
Funding rounds
- May 2025Grant (prize money)$273.7K
- Jan 2025Unattributed$17.4M
- Sep 2023Grant (prize money)$275.7K
- Sep 2023Grant (prize money)$261.3K
Founders & team
Investors
Story Ventures, SemperVirens, Bread and Butter Ventures, Goodwater Capital, Metrodora, Springtime Ventures
Tech stack
CloudflareCloudflare Bot ManagementCore-JsDartDatadogFacebook Pixel
#11
Series A · San Francisco, California · founded 2015 · 34 employees$30Mraised▾
Series A · San Francisco, California · founded 2015 · 34 employees
Provider of digital Precision Medicine company leveraging objective data and passive measurement for mental healthcare.
Fliar Intelligence Index™ 27how this company ranks against its industry peers
Funding
top 31%Talent
top 38%Product
bottom 48%Global
bottom 39%Tech
bottom 37%Market
bottom 31%Funding: Raised $30.0M across 6 rounds · 6 rounds over 10 yrs (0.6/yr) · Last round Series A (Jun 2024)
Talent: 2 named leaders on record · 2 C-suite/founder profiles curated
Product: 1 published app (6.8k installs) · Company stage: Series A
Audience (LinkedIn): 8k LinkedIn followers
Activity (LinkedIn): 2 awards announced in 12 mo
Funding rounds
- Jun 2024Series A$3.5M
- Jan 2023Series A—
- May 2022Series A$4M
- Dec 2020Grant (prize money)—
Founders & team
Investors
Europa, Anthemis Group, SOSV, MiLA Capital, Metavallon, seedToB
Tech stack
CalendlyCloudflareGoogle Font ApiGoogle Hosted LibrariesGoogle WorkspaceHsts
#12
Seed · San Francisco, California · founded 2023$7Mraised▾
Seed · San Francisco, California · founded 2023
Developer of biosensor technology for continuous hormone monitoring. It utilizes DNA-based sensors to provide real-time monitoring of hormone levels in interstitial fluid, a minimally invasive method that unlocks new insights into hormone regulation.
Funding rounds
- Feb 2025Seed$7M
Founders & team
Investors
Redalpine, HAX, Entrepreneur First
Tech stack
CloudflareGoogle Font ApiGoogle Hosted LibrariesHstsHttp/3Jquery
Funding & investor landscape
$4.1Btotal disclosed funding
136companies funded
371disclosed rounds
0rounds last 90 days
Most active investors
Felicis Ventures8 rounds
Notable founders
Colin Espie
Co-Founder · BigHealth
Yael Berman
CEO · BigHealth
Sharam Fouladgar-Mercer
Co-Founder & CEO · Signos
George Netscher
Co-Founder & CEO · SafelyYou
Michael Merzenich
Co-Founder & CSO · BrainHQ
Jeff Zimman
Co-Founder · BrainHQ
Siddhant Bhargava
Co-Founder & CEO · DUSQ
Shalmali Kadu
Co-Founder · DUSQ
Leah Sparks
CEO & Founder · Wildflower Health
Henk Scholten
Co-Founder & COO · Siren
Jie Fu
Co-Founder · Siren
Mary Lou Jepsen
Founder & CEO · Openwater
Prism market signals · United States · country-scoped Prism corpus, 1,253,315 docs
Market landscape — 10 sub-themes by coverage
Share of Disease Self Management coverage by sub-theme.
Regulatory-risk over time falling
Funding & growth over time
funding flat · growth flat
RESEARCH SIGNALS · United States
How research on Digital Health is moving in the United States
A read on the academic research around Digital Health — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 8,843 United States-affiliated papers.
research sentiment over time
200820172026
enthusiastic · positive · guarded tone
Tone is overwhelmingly optimistic and intensifying — the enthusiastic (strongly-positive) share moved 30% → 43% across 2008–2026.
top research entities
- Design Intelligence421
- Harvard University383
- Johns Hopkins University295
- University of North Carolina at Chapel Hill206
- University of Washington173
leading researchers
www.rasitdinc.com · John Torous · Raşit Dinç · Byron J. Powell · Zhu, Zhoule · Ying, Yuqi · Zhu, Junming · Wu, Hemmings
▲
Breakthroughs1,054 · 12%
▲ 9%→12% share
▲1.3× share momentum0 median citations91% since 2021mostly methods-led
Wearable computer research is surging — U.S. papers jumped from 6 to 129, signaling rapid hardware-driven monitoring innovation.
rising sub-themes (early→recent)
- Health care9→240
- Wearable computer6→129
- Health informatics25→140
- Remote patient monitoring11→76
- Informatics10→60
Newly emergingWearable technology 0→48 · Disease 0→30 · Documentation 0→26
Landmark Fostering implementation of health services research findings into practice: a consolidated framework for advancing impl · 14,434 cites
◆
Advancements2,890 · 33%
▲ 28%→33% share
▲1.2× share momentum0 median citations90% since 2021mostly empirical
Psychological intervention research is intensifying — U.S. digital health papers rose from 20 to 320, reflecting growing behavioral telehealth adoption.
rising sub-themes (early→recent)
- Health care36→766
- Health informatics113→495
- Psychological intervention20→320
- Public health34→290
- Intervention (counseling)5→193
Newly emergingTelehealth 0→108 · Cognition 0→57 · Disease 0→49
Landmark A refined compilation of implementation strategies: results from the Expert Recommendations for Implementing Change (ERI · 4,929 cites
▼
Concerns3,580 · 40%
▼ 48%→39% share
▼0.8× share momentum1 median citations85% since 2021mostly empirical
Pandemic and AI-application concerns are newly emerging — both entered at 93 and 74 papers respectively, reshaping digital health risk discourse.
rising sub-themes (early→recent)
- Health care98→1170
- Health informatics213→712
- Public health73→525
- Psychological intervention26→368
- Health administration110→363
Newly emergingPandemic 0→93 · Digital transformation 0→74 · Applications of artificial intelligence 0→74
Landmark Implementation strategies: recommendations for specifying and reporting · 2,697 cites
RESEARCH HOTSPOTS · United States
Where digital health is researched across United States
Location clusters by institution affiliation — each city's volume, stance tone, and a quick read on its hot topic, what's advancing, the opening opportunity, and the main concern.
Boston721 · +0.16
New York440 · +0.14
SF Bay Area368 · +0.18
Chicago238 · +0.17
Seattle213 · +0.18
Philadelphia204 · +0.16
Los Angeles176 · +0.20
Atlanta164 · +0.22
San Diego151 · +0.19
Ann Arbor139 · +0.19
PATENT SIGNAL · United States
Who's filing digital health patents in the United States
United States digital health patent filing is accelerating — 2,575 filings from 1,291 assignees (2016–2025), led by Boeing, Honeywell INT, Advanced Neuromodulation Systems; annual filings 173→270.
2,575 filings1,291 assigneespeak 309/yr2016–2025
filing momentum (YoY 2016–2025)
top patent filers
- Boeing150
- Honeywell INT129
- Advanced Neuromodulation Systems96
- General Electric91
- Hamilton Sundstrand67
- IBM65
- OTIS Elevator50
- Sikorsky Aircraft49
Common questions
How many Disease Self Management companies are there in San Francisco, United States?
Radar tracks 298 indexable Disease Self Management companies headquartered in San Francisco, United States that meet our profile-completeness bar.
What is the total funding raised by Disease Self Management companies in San Francisco, United States?
The Disease Self Management companies in San Francisco, United States on this list have raised a combined $4.1B in disclosed equity funding across 136 funded companies.
Which is the highest-funded Disease Self Management company in San Francisco, United States?
Jawbone is the highest-funded Disease Self Management company in San Francisco, United States, with $877M in disclosed equity funding.
How many Disease Self Management companies in San Francisco, United States are funded?
136 of the 298 Disease Self Management companies in San Francisco, United States on this list have disclosed at least one equity funding round.
How many Disease Self Management unicorns are there in San Francisco, United States?
4 Disease Self Management companies in San Francisco, United States on this list are valued at $1B or more.
Who are the top investors in San Francisco, United States Disease Self Management companies?
The most active investors in San Francisco, United States Disease Self Management companies on this list include Y Combinator, HHS, Rock Health, Berkeley SkyDeck, Felicis Ventures.
Riya SenguptaFinancials
Riya reads income statements for fun. She covers the real money in a sector — revenue, growth, who actually earns — and never met a vague claim she didn't want a number for.