Best Healthcare Companies in Alabama, United States
The 267 best Healthcare companies in Alabama, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Upstream.
Ranked: Best Healthcare companies in Alabama
| # | Company | Disclosed funding | Last round | Stage | Employees | Founded | Tech stack | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Upstream Chain of outpatient physical therapy clinics | $745M | 78 mo ago | Seed | 7,400 | 2004 | WordPressMySQLPHP+20 | — | — |
| 2 | SiO2 Materials Science R&D company focused on manufacturing drugs, molecular diagnostics, materials, and medical devices | $205M | 53 mo ago | Funding Raised | 500 | 2012 | WordPressMySQLPHP+27 | — | — |
| 3 | Hudson Alpha Provider of genomic research, sequencing services, and educational outreach | $111M | 14 mo ago | Funding Raised | 257 | 2005 | WordPress Block EditorwpBakeryElementor+25 | — | — |
| 4 | HighFive Healthcare Provider of dental care consulting services | $102M | 33 mo ago | Series C | 62 | 2018 | Webflow EcommerceWebflowApple iCloud Mail+13 | — | — |
| 5 | Sequel Youth and Family Services Chain of inpatient mental and behavioral therapy centers | $98M | 105 mo ago | Late Stage | 3,915 | 1999 | WordPressMySQLPHP+14 | — | — |
| 6 | TRMC Chain of multispecialty hospital | $50M | 64 mo ago | Funding Raised | 30 | 2019 | — | — | — |
| 7 | SiO2 Materials Science Manufacturer of syringes, vials, and blood preservative devices for multiple therapeutic areas | $48M | 78 mo ago | Series A | 511 | 2011 | — | — | — |
| 8 | Thrive Alabama Provider of primary and specialized healthcare services | $30M | 12 mo ago | Funding Raised | 54 | 1988 | JoomlaPHPYouTube+13 | — | — |
| 9 | ContinuumRx Specialty infusion services | $20M | 130 mo ago | Series B | 66 | 2001 | WordPress Block EditorwpBakeryWordPress+25 | — | — |
| 10 | Uabmedicine Chain of multispecialty hospitals | $16M | 212 mo ago | Funding Raised | 497 | 1996 | WordPress Block EditorWordPressMySQL+22 | — | 1 partnership · 1 expansion |
| 11 | Vitruvias Provider of local news and information via radio and online platforms | $13M | 101 mo ago | Series A | 10 | 2013 | — | — | — |
| 12 | Acclinate Provider of clinical trial services to biopharma sector 9Funding top 38%News top 43%Moat bottom 44%Patents bottom 37% All 7 signals ▾Fundingtop 38% Newstop 43% Moatbottom 44% Patentsbottom 37% Globalbottom 33% Marketbottom 30% Innovationbottom 23% Funding: Raised $12.0M across 4 rounds · 4 rounds over 6 yrs (0.7/yr) News: 2 BI events in 12 mo (of 6 tracked, 4 types) · Top themes: Announcements rank vs industry peers · Fliar Intelligence Index 9/100 | $12M | 4 mo ago | Series A | 33 | 2020 | — | 2 patents Automated patient eligibility assessment and recruitment for clinical trials | — |
| 13 | Christ Health Center The Christ Health Center offers primary care, dentistry, counseling, and medication therapy management… | $12M | 12 mo ago | Funding Raised | 66 | 2009 | WordPressApple iCloud MailMicrosoft 365+20 | — | — |
| 14 | Yuva Biosciences Developer of cosmeceuticals and pharmaceuticals | $9M | 3 mo ago | Seed | 5 | 2018 | — | — | 1 partnership |
| 15 | Alveolus Bio Provider of biotherapeutics services for lung diseases treatment | $8M | 10 mo ago | Seed | 7 | 2021 | WordPressMySQLPHP+13 | — | — |
| 16 | Practice Partners in Healthcare Standalone ambulatory surgery clinic | $7M | 228 mo ago | Series A | 14 | 2005 | — | — | — |
| 17 | My Pet's Vet Chain of veterinary centres | $6M | 52 mo ago | Series A | 16 | 2019 | WordPress Block EditorWordPressMySQL+25 | — | 1 job opening |
| 18 | East Alabama Health Health systems | $5M | 63 mo ago | Acquired | 212 | 1952 | DrupalMariaDBPHP+24 | — | 2 job openings |
| 19 | Hygia Health Services Single-use medical device reprocessor | $3M | 175 mo ago | Acquired | — | 1999 | — | — | — |
| 20 | Rampart Manufacturer of medical devices for multiple therapeutic areas 53Patents top 29%Innovation top 31%Funding top 44%Moat top 45% All 8 signals ▾Patentstop 29% Innovationtop 31% Fundingtop 44% Moattop 45% Techbottom 43% Marketbottom 42% Globalbottom 35% Newsbottom 21% Patents: 24 patents matched (strict assignee match) · 20 filings since 2022 vs 2 in 2017-21 Innovation: 24 patents (top 47% of patent-holders) · 20 filings since 2022 vs 2 in 2017-21 rank vs industry peers · Fliar Intelligence Index 53/100 | $3M | 13 mo ago | Series B | 19 | 2014 | Squarespace CommerceSquarespaceApple iCloud Mail+18 | 24 patents Radiation shielding systems for medical imaging tables and related protective equipment | — |
| 21 | Cullman Regional Medical Center Standalone multi-speciality hospital | $3M | 36 mo ago | Funding Raised | 2 | 1873 | WordPress Block EditorwpBakeryWordPress+30 | — | 1 partnership |
| 22 | OS1 Holdings Provider of orthopedic urgent care services | $3M | 26 mo ago | Seed | — | 2019 | — | — | — |
| 23 | Huntsville Hospital Provider of comprehensive healthcare services across multiple hospital locations | $2M | 24 mo ago | Funding Raised | 5,544 | 1895 | MediaElement.jsUIKitBootstrap+9 | — | 1 partnership · 1 expansion |
| 24 | Children’s of Alabama Chain of children hospitals | $2M | 12 mo ago | Funding Raised | 5,095 5,095 → 3,537 (-31%) | 1911 | Cart FunctionalityApple iCloud MailFroala Editor+36 | — | 1 job opening · 1 award |
| 25 | TPM Research Lab focused on providing patient mobility research services | $2M | 48 mo ago | Seed | 8 | 2020 | — | — | — |
| 26 | Baptist Health Health system | $2M | 215 mo ago | Funding Raised | 599 | 1982 | DrupalApple iCloud MailMariaDB+19 | — | — |
| 27 | Van Heron Labs Provider of pharmaceutical formula testing & commercialization services | $1M | 27 mo ago | Seed | — | 2020 | — | — | — |
| 28 | Sure Med Compliance Provider of a digital health platform for pain management | $1M | 44 mo ago | Seed | 11 | 2015 | Cart FunctionalitySquarespace CommerceSquarespace+14 | — | 1 partnership |
| 29 | Diatherix Eurofins Developer of a proprietary PCR technology for diagnostic services | $990K | 137 mo ago | Seed | 153 | 2007 | WordPressApple iCloud MailMicrosoft 365+23 | — | — |
| 30 | Infirmary Health Provider of acute and post-acute healthcare services | $749K | 60 mo ago | Funding Raised | 5,409 | 1910 | ScorpionApple iCloud MailGoogle Maps+17 | — | 1 launch |
| 31 | DCH Health System Provider of comprehensive healthcare services across multiple locations | $594K | 189 mo ago | Funding Raised | 2,076 | 1923 | Windows ServerMicrosoft ASP.NETBootstrap+10 | — | 3 job openings |
| 32 | Personal Best Standalone wellness centre | $431K | 51 mo ago | Early Stage | 16 | 1982 | Windows ServerMicrosoft ASP.NETIIS+12 | — | — |
| 33 | St. Vincent's Health System Network of multispeciality hospitals | $368K | 180 mo ago | Early Stage | 1,084 | 1898 | — | — | 2 expansions · 1 award |
| 34 | RMC Chain of multi speciality hospitals | $348K | 218 mo ago | Acquired | 424 | 1907 | WordPressMySQLPHP+29 | 4 patents Ergonomic furniture and support systems for seating and posture improvement. | — |
| 35 | NuTech Distributor of amniotic stem-cell-based products 53Patents top 16%Product top 18%Innovation top 21%Moat top 41% All 8 signals ▾Patentstop 16% Producttop 18% Innovationtop 21% Moattop 41% Talentbottom 45% Techbottom 42% Globalbottom 40% Fundingbottom 23% Patents: 664 patents matched (strict assignee match) · 257 filings since 2022 vs 266 in 2017-21 Product: 6 distinct product lines rank vs industry peers · Fliar Intelligence Index 53/100 | $325K | 184 mo ago | Early Stage | — | 1994 | — | 664 patents Patents concentrated in chemistry & materials | — |
| 36 | Hausted Medical device distributors 7Tech bottom 47%Talent bottom 45%Funding bottom 30%Global bottom 25% All 5 signals ▾Techbottom 47% Talentbottom 45% Fundingbottom 30% Globalbottom 25% Marketbottom 12% Tech: 24 technologies across 3/8 capability areas · Cloud: Cloudflare Talent: 1 named leader on record rank vs industry peers · Fliar Intelligence Index 7/100 | $250K | 195 mo ago | Acquired | 6 | 1949 | WordPress Block EditorWordPressMySQL+21 | — | — |
| 37 | One Nineteen GI ASC Standalone ambulatory surgery clinics | $175K | 27 mo ago | Seed | — | — | — | — | — |
| 38 | Kirklin Solutions Provider of technology services for healthcare sector | $150K | 32 mo ago | Seed | — | 2022 | — | — | 1 partnership |
| 39 | Shelby Ambulatory Surgery Standalone ambulatory surgery center | $150K | 33 mo ago | Seed | — | 2012 | — | — | — |
| 40 | Springhill Medical Center Provider of comprehensive medical services and treatments | $149K | 60 mo ago | Funding Raised | — | 1975 | DrupalPHPVarnish+13 | — | 1 job opening · 2 expansions |
| 41 | Alabama Retailer of cannabis despensaries | $100K | 35 mo ago | Seed | — | 2021 | — | — | — |
| 42 | Creek Leaf Wellness Standalone wellness center | $100K | 44 mo ago | Seed | — | 2022 | — | — | — |
Top 12 Healthcare companies in Alabama
#1
Series A · Birmingham, Alabama · founded 2020 · 33 employees$12Mraised▾
Provider of clinical trial services to biopharma sector
- Feb 2026Series A$3.5M
- May 2024Series A$7M
- Oct 2022Series A$4.9M
- Oct 2022Grant (prize money)—
#2
Seed · Birmingham, Alabama · founded 2018 · 5 employees$8.6Mraised▾
Developer of cosmeceuticals and pharmaceuticals
- Mar 2026Seed$1.1M
- Feb 2024Seed$7.5M
#3
Funding Raised · Huntsville, Alabama · founded 2005 · 257 employees$110.7Mraised▾
Provider of genomic research, sequencing services, and educational outreach. It conducts research in areas such as rare diseases, neurological disorders, cancer, and plant genomics. The organization offers genome sequencing and analysis services. Additionally, it provides educational programs and resources for students, educators, and healthcare professionals, fostering genomic literacy. Its research contributes to advancements in human health and agriculture.
- Apr 2025Grant (prize money)$1.4M
- Apr 2025Grant (prize money)$2M
- Mar 2025Grant (prize money)$1.2M
- Feb 2025Grant (prize money)$725.5K
#4
Funding Raised · Huntsville, Alabama · founded 1988 · 54 employees$29.8Mraised▾
Provider of primary and specialized healthcare services including adult primary care, pediatrics, behavioral health, and HIV/STI care. It offers preventative medicine, chronic care management, and contraceptive services. The organization also provides outreach and education programs focusing on health education and HIV testing. Services are delivered through multiple clinic locations. They employ a team of medical providers including physicians and nurse practitioners.
- 2025Grant (prize money)$674.9K
- 2025Grant (prize money)$674.9K
- 2024Grant (prize money)$2.2M
- 2023Grant (prize money)$1.8M
#5
Seed · Birmingham, Alabama · founded 2021 · 7 employees$8.4Mraised▾
Developer of COPD drugs intended for the prevention and treatment of chronic lung diseases. The company's drugs offer therapeutics that specifically target lung diseases developed by an interdisciplinary team of physicians, researchers, and innovators collaborating at the intersection of respiratory medicine, microbiome science, and drug delivery modalities, enabling medical professionals to target microbiome-based pathways to alter the course of respiratory diseases among the patients.
- Aug 2025Seed—
- Apr 2025Grant (prize money)$2.3M
- Feb 2025Grant (prize money)$2.3M
- Mar 2023Grant (prize money)$2.5M
#6
Funding Raised · Birmingham, Alabama · founded 2009 · 66 employees$11.6Mraised▾
The work we are doing at Christ Health Center goes well beyond treating the sick. We are committed to the physical, mental and spiritual health and well-being of each of our patients. More than simply seeing the sick made well, at Christ Health Center we strive to see the well made whole and to see each patient living life abundantly. Our patients have access to the very best in primary care, dental services and professional counseling as well as medication therapy management through our on-site pharmacy.
- May 2025Grant (prize money)$64.7K
- Mar 2025Grant (prize money)$704.6K
- Jan 2025Grant (prize money)$10.8M
#7
Funding Raised · Birmingham, Alabama · founded 1911 · 5095 employees$2.2Mraised▾
Chain of children hospitals
- 2025Grant (prize money)$2.2M
#8
Series B · Birmingham, Alabama · founded 2014 · 19 employees$3.1Mraised▾
Manufacturer of medical devices for multiple therapeutic areas
- Apr 2025Series B$21.6M
- Sep 2020Series A$3.1M
#9
Series C · Birmingham, Alabama · founded 2018 · 62 employees$102.2Mraised▾
Provider of dental care consulting services
- Sep 2023Conventional Debt—
- Jun 2023Series C$100M
- Nov 2018Seed$2.2M
#10
Seed · Birmingham, Alabama · founded 2004 · 7400 employees$745Mraised▾
Chain of outpatient physical therapy clinics
- Nov 2019Conventional Debt$745M
- Dec 2015Seed—
#11
Funding Raised · Auburn, Alabama · founded 2012 · 500 employees$205Mraised▾
R&D company focused on manufacturing drugs, molecular diagnostics, materials, and medical devices. Its portfolio includes biological drugs, nucleic acid-based vaccines, viral vectored therapies, blood collection tubes, syringes, vials, blood preservation, and cell & gene therapies.
- Dec 2021Conventional Debt$205M
#12
Funding Raised · Huntsville, Alabama · founded 1895 · 5544 employees$2.5Mraised▾
Provider of comprehensive healthcare services across multiple hospital locations. It offers a wide array of services, including cancer care, emergency and trauma services, heart care, neurology, orthopedics, spine and neurology services, stroke care, surgery, women's and children's health, and wellness programs. The organization also provides support services such as medical records, patient advocacy, and a patient portal. It maintains a commitment to patient-centered care and quality-focused processes.
- 2024Grant (prize money)$2.5M
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Healthcare coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising