Healthtech Industry Landscape of Chicago
461 Healthtech companies in Chicago, in one picture: who is hiring, who is raising money, who founded them, what the news is about, which skills employers want and where the research is going. Updated September 2026.
Who leads Healthtech in Chicago
Shows the top healthtech firms in Chicago by size, funding, hiring activity, and media coverage, noting 461 companies, 53 currently hiring, and 144 with recent funding rounds.
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R1 RCM13last posted Aug 2026
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Sittercity10last posted May 2026
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RLDatix8last posted Apr 2026
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HuFriedyGroup6last posted Jun 2026
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Xeris Pharmaceuticals6last posted Jun 2026
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Veradigm6last posted Feb 2026
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Annexus Health5last posted Feb 2026
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Adoreal5last posted May 2026
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Tempus$760MSeries G · Oct 2022
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Outcome Health$532.9MSeries C · Jul 2017
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Upfront Healthcare$95.5MSeries C · Jun 2023
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Higi$95.2MSeries C · Jun 2020
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NOCD$85MSeries C · Jan 2023
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KeyCare$84.6MSeries A · Mar 2026
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Allscripts$156.2MFY2022 filing
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Neopenda$103ksnapshot Apr 2020
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AVIA177tracked employees
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Madison Industries168tracked employees
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Kalderos110tracked employees
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GE Healthcare62.7%185 tracked events
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Emmi3.1%9 tracked events
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Thoughtful2.0%6 tracked events
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Dina1,195articles in the window
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Performance Health34articles in the window
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Nucle AI24articles in the window
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See all 461 Healthtech companies in Chicago
Filter by funding, headcount, hiring and location, and export the list.
How the Healthtech ecosystem in Chicago grew, 2016–2025
Displays the annual count of new healthtech startups from 2016 to 2025, highlighting a peak of 36 companies founded in 2019 and only one in 2025.
The Healthtech market map of Chicago: what these companies actually do
Breaks down the product types these firms develop and their revenue models, with enterprise tech (259 firms) and subscription billing (311 firms) being the most common.
- Enterprise Tech259 companies · $3.3B raised · 36 hiring
- Consumer Digital142 companies · $597.1M raised · 12 hiring
- Enterprise Software141 companies · $2.3B raised · 21 hiring
- SaaS82 companies · $1.4B raised · 16 hiring
- Life Sciences79 companies · $1.4B raised · 12 hiring
- Healthtech SaaS76 companies · $1.3B raised · 13 hiring
- B2C E-Commerce30 companies · $129.7M raised · 3 hiring
- Hospital at Home25 companies · $132M raised · 3 hiring
- Loneliness Economy23 companies · $114M raised · 1 hiring
- At Home Diagnostics19 companies · $81.7M raised · 4 hiring
- Digital Diagnostics Platforms18 companies · $108M raised · 1 hiring
- IoT in Healthcare17 companies · $137.8M raised · 3 hiring
Monetization
How Healthtech companies make money
How many companies earn revenue each way. Plenty use more than one model, so the counts add up to more than the sector.
Funding, M&A and the deals moving Healthtech in Chicago
Lists 189 corporate actions over the past two years, including earnings releases (42), mergers and acquisitions (35), and key personnel changes (31).
- FundingKeyCare, the nation's first Epic-based virtual care company, today announced the close of a $27.4 million financing round.2026-03-03
- M&AEarlier this week, NOCD announced the acquisition of trauma-informed provider Rebound Health.2026-01-29
- M&AGE HealthCare has announced the acquisition of Intelerad.2025-12-09
- M&AEmmi is acquiring The English Cheesecake Company, a UK-based producer of "premium" desserts.2025-11-25
- M&AAVIA today announced the acquisition of Panda Health, a strategic move that will expand their AVIA Marketplace platform and will further support healthcare providers with their digital health strategies.2025-10-15
- M&AEversana, a leading global player in pharmaceutical commercialization services, has merged with Waltz Health, a technology‑driven healthcare company, in a move that could transform how life sciences companies connect with payers and patients in the United States. Announced on August 26, 2025, the deal combines Eversana’s end‑to‑end commercialization model with Waltz Health’s AI‑powered drug‑pricing marketplaces and direct‑to‑payer platforms.2025-08-27
- M&ABrightstar Capital Partners (“Brightstar”), a private equity firm focused on investing in business services, industrials, consumer, and government services and technology companies, announced today that it has acquired Analyte Health (“Analyte” or the “Company”).2025-08-04
- FundingThe raise builds upon $12.5 million in prior seed investment that was used to obtain FDA 510(k) clearance and begin early commercialization of HOTWIRE™2025-06-20
- M&AMadison Industries, one of the world's largest privately held companies, announced the successful acquisition of Research Products Corporation (RPC).2025-05-07
- M&ACreative Foam Corporation, a US provider of engineering solutions for the transportation, health and consumer/industrial sectors, purchased from AccuMED Holdings Corp. medical equipment manufacturer and its Dominican branch, which operates as a free zone company.2025-04-04
Mergers and acquisitions
Deals from the last 24 months where a Healthtech company in Chicago was the buyer or the one bought, newest first. “Undisclosed” means the price was never published — not that the deal was worth nothing.
| Acquirer | Target | Deal value | Status | Date |
|---|---|---|---|---|
| $2.3B | Announced | 2026-04-15 | ||
| undisclosed | Announced | 2026-02-06 | ||
| $51M | Announced | 2026-01-01 | ||
| $1.4B | Completed | 2026-01-01 | ||
| undisclosed | Announced | 2025-11-25 | ||
| undisclosed | Completed | 2025-11-25 |
Who is listing, hiring leaders, launching and winning work
Provides details on notable corporate events such as leadership changes and new customer contracts within the sector.
Clarix ImagingRay Gerena · Appointment → Senior Vice President of U.S. SalesSep 2025
Prenosiswon US Department of Health and Human Services\' Biomedical Advanced Research and Development AuthorityJan 2026
Regroup Therapywon circular materialsDec 2025
Half of these companies grew revenue faster than +3.0%, half slower.
Who is building Healthtech in Chicago
Profiles 273 founders and CEOs across 191 companies, noting frequent alma maters like the University of Chicago (15) and prior employers such as McKinsey (1).
Ex-Cambia Health Solutions, The Advisory Board Company, AirStrip. Western Michigan University BA 1996, University of Illinois Chicago MBA
Ex-Buckland International Education. Pomona College BA 2017
Founder & CEO Back 9 Healthcare Consulting, Cobblestone Ventures, ex- Founder Healthfinch, MDLIVE, RiseHealth. University of Pennsylvania BSE 1988
Ex-Vivante Health, Virta Health, Humana. Vanderbilt University BS, Northwestern University - Kellogg School of Management MBA
Kalderos, ex-Ia Collaborative, ex-Polsky Center At The University Of Chicago, IIT Institute of Design, 2012
Ex-CEO Falcon Consulting Group, XSELL Technologies, Epic. University of Maryland - Robert H. Smith School of Business 2008…
Ex- Acutus Medical. University of Iowa BSE 2014
Nucleai, ex-Spacepharma, ex-Nooly, Technion-Machon Technologi Le' Israel, 2002
Ex-Northern Trust Corporation, VMS BioMarketing, Obama for America, Endocyte. Indiana University Bloomington BA 2013
- flagged as repeat founders4
- no repeat-founder flag215
- women45
- men200
Look up the people behind Healthtech companies in Chicago
Search founders, executives and operators by company, role and location.
Who funds Healthtech in Chicago
Summarizes 346 funding rounds since 2016 from 305 investors, with the typical round size at $2.2 million.
| Investor · most active investors since 2016 | Rounds | Led | Latest |
|---|---|---|---|
| HHS | 38 | — | Aug 2025 |
| 7wire Ventures | 9 | 3 | Sep 2023 |
| Pritzker Group | 7 | 3 | Oct 2019 |
| Impact Engine | 7 | 2 | Feb 2021 |
| HPA | 6 | 1 | Oct 2020 |
| OSF HealthCare | 5 | 4 | Dec 2018 |
| New Enterprise Associates | 5 | 3 | Mar 2020 |
| T. Rowe Price | 5 | 3 | Dec 2020 |
| Chicago Ventures | 5 | 3 | Sep 2021 |
| Revolution | 5 | 2 | Jun 2023 |
The typical round is $2.2M — half were bigger, half smaller.
The biggest Healthtech funding rounds in Chicago
Highlights the largest disclosed round—Outcome Health’s $500 million Series C—and lists ten other major recent funding events.
| Company | Round | Size | When | Backers |
|---|---|---|---|---|
| Series Cmega-round | $500M | May 2017 | CapitalG, Pritzker Group, Balyasny Asset Management +3 more | |
| Series G | $200M | Dec 2020 | Google, Novo Holdings, Baillie Gifford +2 more | |
| Series F | $200M | May 2019 | New Enterprise Associates, Novo Holdings, Revolution +3 more | |
| Series E | $110M | Aug 2018 | T. Rowe Price, Revolution, New Enterprise Associates +1 more | |
| Series G | $100M | Mar 2020 | Baillie Gifford, Franklin Templeton Investments, T. Rowe Price +2 more | |
| Series D | $80M | Mar 2018 | New Enterprise Associates, Revolution, T. Rowe Price +1 more | |
| Series C | $70M | Sep 2017 | New Enterprise Associates, Revolution | |
| Series C | $61.5M | Aug 2022 | Baird Capital, Echo Health Ventures, First Trust Capital Partners +3 more | |
| Series C | $57M | Mar 2020 | — | |
| Series B | $48.5M | Mar 2022 | Aldrich Capital Partners |
53 venture rounds with a disclosed amount in the window.
Seed$1.5MMar 2026
Series B$3MFeb 2026
How this industry appears in the news
Counts 41,139 news pieces about Chicago healthtech in the last year, most often covering administrative and political topics.
- 1,836
- 1,195
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38 Healthtech companies here were named in the news over this period.
Watch Healthtech coverage in United States as it happens
Prism follows these subjects story by story — which companies are named, what is said about them and how the tone moves.
Healthtech jobs in Chicago: who is hiring and what they ask for
Reports 1,414 job listings from 60 firms in the past year, with common skills like Excel and SQL and a median salary of $52 k.
Demand
The Skills Employers Ask For
What Healthtech employers in Chicago put in their job ads. The bar is how many postings ask for it; the arrow shows whether demand grew or shrank against the year before.
- excel14▲
- word8▲
- powerpoint7▲
- salesforce6▲
- sql6▲
- hipaa5▲
- outlook5▲
- crm5▲
- power bi5▲
- microsoft office5▲
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12 Healthtech-relevant internships in India were advertised over the same 12 months.
What the research says
The Healthtech research read is national: 8,843 United States-affiliated papers, clustered into themes such as Challenges in Drug Discovery, Telehealth Access and Inclusion, Telemedicine Safety and Cost Concerns, Health Informatics Implementation Risks. It is measured at country level, so it is the same signal for every city in United States — the full read, with the theme clusters, growth and blind spots, lives on the national page.
Read the full Healthtech research analysis for United States →
Go deeper on Healthtech research and innovation
Research themes, patent activity and the companies commercialising them, in one place.
Track Healthtech in Chicago beyond this page
Radar finds and filters the companies. Prism watches what is being said about them.
Direct contact details for the people on this page are held in Fliar Radar, behind its own access controls.
Where demand signals run ahead of mapped supply — Chicago
Every demand signal in Chicago’s newsflow, measured as a share of the city’s own coverage (2025-05-01 to 2026-05-01, against the year before), then scored beside family-matched supply — the companies in each signal’s mapped healthtech categories — as within-page percentiles. The gap is signal percentile minus supply percentile — a prioritisation clue in percentile points, not a market size.
The opportunity, in one view
Where the signals are loudest
Each city’s reading is a share of its own coverage, so a loud smaller city can outrank a large one; rows follow each story’s primary city tag. Rows cover all of the United States for this page's signal families; Chicago is marked.
showing the ten highest-signal cities of 12 readings.
Inside the three leading signals
Air pollution
the operating hypothesis
Sustained air-quality stress can pull respiratory and cardiac care demand with it.
Ageing & elder care
the operating hypothesis
An ageing base can shift demand toward geriatric, home and chronic care.
Cancer burden
the operating hypothesis
Cancer burden can pull screening, diagnostics and oncology capacity demand.
For who is hiring, raising and leading here, see this page’s leader boards and market map above.
Related research & where the coverage is heading
The research below carries both a healthtech term and this page’s geography in its title — context for the boards above, not proof of any single number. The keywords are the fastest-growing terms in Chicago coverage of this page's demand families, measured as a share of that coverage year-over-year so volume drift cancels.
Related research · healthtech in Chicago
What’s growing in this coverage
Prism
Take these signals further
Everything on this board comes from the same data Prism serves live — the coverage, the companies named in it, and how the tone moves.
Explore Prism
The research and news intelligence layer behind this page — follow any of these signals story by story, in reports that refresh as the coverage moves.
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Your categories, your competitors and the demand signals that move your market — in one live view that updates as the coverage does, built for your team on the same data behind this page.
Request a dashboardEvery company behind these supply counts is tracked on Radar — hiring, funding, filings and headcount, live and searchable.