Japan’s
healthtech industry,
in focus.

Health System Resilience

19.0% of this theme group

Examines factors and methods for building resilient health care systems and administrations.

Health informatics (400) · Health administration (281) · Nursing research (250) · Public health (273)

Resilient Health Care: a systematic review of conceptualisations, study methods and factors that develop resilience

Health systems resilience in practice: a scoping review to identify strategies for building resilience

Complex Disease Drug Development

18.9% of this theme group

Discusses challenges of multi‑target discovery, repurposing, and design for intricate disease pathways.

Drug discovery (321) · Drug (197) · Drug development (103) · Disease (155)

A perspective on multi‐target drug discovery and design for complex diseases

Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer

Digital Health Integration

15.9% of this theme group

Analyzes how digital tools affect universal coverage, patient engagement, and health behavior change.

Digital health (627) · Health care (357) · Digital transformation (69) · eHealth (97)

Technology and Universal Health Coverage: Examining the role of digital health

Engagement With and Acceptability of Digital Media Platforms for Use in Improving Health Behaviors Among Vulnerable Families: Systematic Rev

Telehealth Implementation

14.7% of this theme group

Reviews practical and methodological issues surrounding remote clinical services and rehabilitation.

Telemedicine (604) · Telehealth (394) · Health care (334) · Telerehabilitation (53)

Opportunities and challenges for telehealth within, and beyond, a pandemic

Strategies for Evaluating Telehealth

Precision Oncology Challenges

11.7% of this theme group

Focuses on molecular diagnostics, biomarker use, and resistance in personalized cancer treatment.

Precision medicine (480) · Personalized medicine (238) · Disease (116) · Precision oncology (28)

Personalized Cancer Medicine: Molecular Diagnostics, Predictive biomarkers, and Drug Resistance

Personalizing Oncology: Perspectives and Prospects

Medical Device Regulation

10.9% of this theme group

Explores risk analysis, energy sources, and regulatory frameworks for emerging medical equipment.

Medical device (221) · Wearable computer (50) · Medical equipment (27) · Risk analysis (34)

Energy sources and their development for application in medical devices

Medical Devices and Health — Creating a New Regulatory Framework for Moderate-Risk Devices

Pandemic‑Driven Telemedicine

8.8% of this theme group

Measures COVID‑19 impacts on telehealth usage and evaluates specialty-specific remote care experiences.

Pandemic (394) · Coronavirus disease 2019 (274) · 2019-20 coronavirus outbreak (69) · Telemedicine (258)

Quantifying the Impact of COVID-19 on Telemedicine Utilization: Retrospective Observational Study

Telemedicine Evaluations in Neuro-Ophthalmology During the COVID-19 Pandemic: Patient and Physician Surveys

Telemedicine Outcome Concerns

19.8% of this theme group

Highlights uncertainties about effectiveness, patient satisfaction, and long‑term health impacts of remote care.

Telemedicine (762) · Telehealth (476) · Telerehabilitation (118) · Health care (319)

The Role of Telemedicine in Improving Healthcare Outcome: A Review

Assessing the Efficiency and Patient Satisfaction of Telemedicine in Managing Chronic Health Conditions

E‑Health Adoption Barriers

19.8% of this theme group

Identifies practical and quality‑assessment obstacles when deploying digital health tools in diverse settings.

Health informatics (239) · Health administration (157) · Nursing research (113) · Medical device (92)

Challenges of using e-health technologies to support clinical care in rural Africa: a longitudinal mixed methods study exploring primary hea

Development and analysis of quality assessment tools for different types of patient information – websites, decision aids, question prompt l

Pharmacogenomics Uncertainty

15.3% of this theme group

Discusses limits of biomarkers and predictive models for drug metabolism and regulatory acceptance.

Drug discovery (202) · Drug (160) · Pharmacogenomics (109) · Pharmacogenetics (64)

Biomarkers: Opportunities and Challenges for Drug Development in the Current Regulatory Landscape

Can We Predict Clinical Pharmacokinetics of Highly Lipophilic Compounds by Integration of Machine Learning or In Vitro Data into Physiologic

Digital Mental‑Health Risks

14.7% of this theme group

Examines adoption patterns, efficacy gaps, and user‑experience challenges in digital psychological interventions.

Digital health (480) · Psychological intervention (265) · Mental health (159) · Health care (262)

Digital Health Interventions to Enhance Prevention in Primary Care: Scoping Review

Digital Health Interventions for Promoting Healthy Aging: A Systematic Review of Adoption Patterns, Efficacy, and User Experience

COVID‑19 Telehealth Equity

11.2% of this theme group

Explores clinician perspectives and adoption disparities of remote services during pandemic conditions.

Pandemic (431) · Coronavirus disease 2019 (360) · Telemedicine (348) · 2019-20 coronavirus outbreak (77)

Community Mental Health Clinicians’ Perspectives on Telehealth During the COVID-19 Pandemic: Mixed Methods Study

Exploring Ophthalmologists’ Adoption of Telemedicine during the COVID-19 Pandemic: A Mixed Methods Study

Precision Medicine Adoption

10.3% of this theme group

Analyzes awareness gaps, implementation hurdles, and ethical considerations in personalized oncology.

Precision medicine (249) · Personalized medicine (164) · Cancer (103) · Oncology (57)

Awareness, Understanding, and Adoption of Precision Medicine to Deliver Personalized Treatment for Patients With Cancer: A Multinational Sur

Role of Proteins in Oncology: Advances in Cancer Diagnosis, Prognosis, and Targeted Therapy—A Narrative Review

AI in Clinical Decision‑Making

8.8% of this theme group

Considers ethical, reliability, and transformative learning issues surrounding artificial intelligence in health care.

Applications of artificial intelligence (102) · Transformative learning (77) · Health care (188) · Precision medicine (102)

Artificial intelligence in healthcare: revolutionizing precision medicine, predictive analytics, and ethical considerations in autonomous di

Artificial Intelligence in Medicine: Transforming Diagnosis, Treatment, and Healthcare Delivery

Digital Health Usability

18.0% of this theme group

Proposes models and design approaches to improve clinical usability of emerging digital health technologies.

Digital health (282) · Health care (348) · Health informatics (142) · Psychological intervention (156)

Development of an Evidence-Based Conceptual Model of the Health Care Sector Under Digital Transformation: Integrative Review

HCI-modelling for improving the clinical usability of digital health technologies

In‑Silico Drug Screening

16.5% of this theme group

Highlights computational docking and virtual screening as pathways to discover new therapeutics.

Drug discovery (281) · In silico (99) · Drug (155) · Docking (85)

Exploring Cimetidine\nas a Potential Therapeutic Attenuator\nagainst Amyloid Formation in Parkinson’s Disease: Spectroscopic\nand Microscopi

Design, Synthesis,\nand Biological Evaluation of 5‑Formyl-pyrrolo[3,2‑<i>b</i>]pyridine-3-carboxamides as New Selective, Potent,

Computational Chemistry for Discovery

13.8% of this theme group

Shows how molecular docking and chemical space exploration accelerate targeted drug design.

Drug discovery (536) · Computational biology (222) · Drug (224) · Chemical space (66)

Assessing molecular docking tools: understanding drug discovery and design

Molecular Docking in Computer-Aided Drug Discovery: A Powerful Tool for Targeted Therapeutics

Remote Physical Therapy

13.7% of this theme group

Explores telehealth applications for senior care, palliative communication, and rehabilitation research.

Telemedicine (475) · Telehealth (353) · Telerehabilitation (87) · Physical therapy (75)

Urgent and non-emergent telehealth care for seniors: Findings from a multi-site impact study

Telehealth for the study of palliative care communication: opportunities, methodological challenges, and recommendations

Genomics‑Driven Personalization

12.7% of this theme group

Advances precision medicine through pharmacogenomics, heterogeneity embrace, and deep‑learning treatment planning.

Precision medicine (283) · Personalized medicine (216) · Disease (142) · Pharmacogenomics (61)

Pathways to personalized medicine—Embracing heterogeneity for progress in clinical therapeutics research in Alzheimer's disease

Deep Learning for Precision Medicine: Advancing Personalized Treatment Plans in Oncology

Wearable IoT Monitoring

12.7% of this theme group

Describes wearable and Internet‑of‑Things solutions for continuous patient monitoring in remote contexts.

Wearable computer (117) · Medical device (84) · Remote patient monitoring (76) · Internet of Things (49)

Wearable technology. Health-care solutions for a growing global population.

IoT Based Effective Wearable Healthcare Monitoring System For Remote Areas

Biomarker‑Based Cancer Stratification

12.5% of this theme group

Focuses on bioinformatics analyses of circulating tumor cells to tailor cancer therapies.

Cancer (241) · Precision medicine (207) · Breast cancer (90) · Lung cancer (44)

Bioinformatics-Based Analysis of Circulating Tumor Cells: A Methodological Overview of Personalized Cancer Treatment

[Molecular biomarkers in breast cancer : advances in precision medicine].

Tokyo

40.1% across the displayed hubs

3 companies hiring · $419.3M disclosed funding

Shibuya

12.8% across the displayed hubs

0 companies hiring · $43.5M disclosed funding

Minato City

11.8% across the displayed hubs

0 companies hiring · $169.3M disclosed funding

Osaka

8.9% across the displayed hubs

0 companies hiring · $9.8M disclosed funding

Chiyoda City

8.1% across the displayed hubs

3 companies hiring · $76.1M disclosed funding

Kyoto

7.4% across the displayed hubs

1 companies hiring · $42.6M disclosed funding

Shinjuku City

5.4% across the displayed hubs

0 companies hiring · $50.4M disclosed funding

Bunkyo

5.4% across the displayed hubs

0 companies hiring · $42.1M disclosed funding