Japan’s
life sciences industry,
in focus.

Sustainable Biofuel and Biomass Production

17.3% of this theme group

Researchers discuss challenges in using microbes and plants for renewable fuels and biorefinery processes.

Biofuel (41) · Synthetic biology (53) · Biomass (45) · Biorefinery (28)

A review on the plant microbiome: Ecology, functions, and emerging trends in microbial application

Biofertilizers: An ecofriendly technology for nutrient recycling and environmental sustainability

Food Safety and Processing Risks

16.8% of this theme group

Papers highlight microbial hazards and nutritional impacts linked to food manufacturing and consumer health.

Food safety (130) · Food processing (74) · Food products (50) · Human health (90)

Microbial Risks in Food: Evaluation of Implementation of Food Safety Measures

Nutritional quality and processing of plant proteins for healthy and sustainable foods

Gene Expression and mRNA Therapeutics

15.8% of this theme group

Studies examine hurdles in controlling gene activity, mRNA delivery, and cell‑culture models for medicine.

Messenger RNA (28) · Gene (44) · Cell culture (23) · Gene expression (24)

Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research

Evolution of Approaches to the Development, Life Cycle Control, and Interchangeability of Veterinary Biosimilars Based on Hemoproteins (with

Crop Nutrition and Food Security

15.4% of this theme group

Research points to difficulties in improving nutrient uptake, breeding efficiency, and resilient food supplies.

Agriculture (208) · Crop (84) · Food security (86) · Germplasm (39)

Revisiting fertilisers and fertilisation strategies for improved nutrient uptake by plants

Breeding for nutrient use efficiency in crop plants: Mechanistic insights, genetic determinants, and emerging breeding technologies

Plant Disease Management and Pest Resistance

15.3% of this theme group

Works address obstacles in innate immunity, pathogen interactions, and integrated pest‑control strategies.

Fungicide (44) · Integrated pest management (54) · Host (41) · Disease management (32)

Innate Immunity in Plants: An Arms Race Between Pattern Recognition Receptors in Plants and Effectors in Microbial Pathogens

Insect-Borne Plant Pathogens and Their Vectors: Ecology, Evolution, and Complex Interactions

Antimicrobial Resistance Across Sectors

9.9% of this theme group

Authors flag the spread of drug‑resistant microbes in humans, livestock, and the environment.

Antibiotic resistance (301) · Antimicrobial (164) · Antibiotics (126) · Drug resistance (49)

Antimicrobial resistance in humans, livestock and the wider environment

Antimicrobial use and resistance

Miscellaneous Biological and Chemical Topics

9.4% of this theme group

Papers cover a range of unrelated scientific themes, indicating broader disciplinary noise.

Order (19) · NAD+ kinase (11) · Human being (12) · Sodium (11)

Modalidade, polaridade e legibilidade em resumos académicos: uma análise comparativa multidisciplinar

Obiteljska grupna konferencija: prilika za građansko pravosuđe?

Cellular Toxicity and Oxidative Stress Assays

21.5% of this theme group

Studies caution about interpreting in‑vitro and in‑vivo stress measurements for safety evaluation.

In vivo (32) · Flow cytometry (16) · In vitro (27) · Oxidative stress (19)

Effects of Microplastics on Cell Viability, Phagocytic Activity and Oxidative Stress in Human Peripheral Blood Mononuclear Cells

Cell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes

Genomic Selection and Trait Prediction Limits

14.6% of this theme group

Research warns of uncertainties when applying genomic tools to plant breeding and animal production.

Agriculture (45) · Selection (26) · Production (28) · Trait (16)

Genomic selection in plant breeding: from theory to practice

Future Directions for Sustainable Poultry Feeding and Product Quality: Alternatives from Insects, Algae and Agro-Industrial Fermented By-Pro

Feed Additives and Human Dietary Shifts

13.9% of this theme group

Papers advise careful assessment of bioactive feed compounds and plant‑protein replacements for health impacts.

Feed additive (27) · Animal feed (28) · Feed conversion ratio (32) · Health benefits (30)

Natural Bioactive Compounds as Feed Additives: Strategies for Sustainable and Functional Livestock Production

The impact of substituting animal with plant protein foods in adults’ self-selected diets on environmental, nutritional, and health outcomes

Food Contaminants and Regulatory Concerns

13.6% of this theme group

Works highlight safety gaps and regulatory challenges surrounding novel food ingredients and additives.

Food safety (66) · Hygiene (21) · Contamination (29) · Food contaminant (20)

Caffeine (1, 3, 7‐trimethylxanthine) in Foods: A Comprehensive Review on Consumption, Functionality, Safety, and Regulatory Matters

Insect-derived food colorants: Chemistry, applications, safety, and regulatory perspectives

DNA Damage and Repair Mechanisms

13.5% of this theme group

Authors note complexities in measuring genomic integrity and interpreting repair pathway data.

Gene (41) · DNA damage (26) · DNA repair (13) · Gene expression (20)

Comparative analysis of microRNA expression in serum and plasma in patients screened for BRCA1 or BRCA2 mutations

Homologous recombination deficiency in primary ER-positive and HER2-negative breast cancer

Antibiotic Use and Co‑Selection Pressures

11.7% of this theme group

Studies caution that antimicrobial practices can foster resistance across drugs, biocides, and metals.

Antibiotic resistance (59) · Antibiotics (47) · Antimicrobial (38) · Bacteria (26)

Antibiotic use in food animals worldwide, with a focus on Africa: Pluses and minuses

Co-Selection of Resistance to Antibiotics, Biocides and Heavy Metals, and Its Relevance to Foodborne Pathogens

Pesticide Resistance and Biological Control

11.3% of this theme group

Research points to the need for careful dosing and ecological considerations when managing pest resistance.

Pesticide (34) · Integrated pest management (21) · PEST analysis (30) · Biological pest control (20)

The use of fungal entomopathogens as endophytes in biological control: a review

Managing pesticide resistance by changing the applied dose: a modeling analysis incorporating pesticide persistence and including low-dose m

Advanced Antibody and Imaging Technologies

17.4% of this theme group

Papers explore novel antibody formats and fluorescence methods for in‑vivo diagnostics and cell analysis.

Antibody (70) · In vivo (81) · Fluorescence (40) · Flow cytometry (50)

Figure 4 from Ancestrally Diverse Autologous Patient-Derived Organoid–Immune Cell Coculture Platform for Addressing Immunotherapeutic Outcom

Preparation, Characterization, and Binding Mechanism of Nanobodies Targeting Multiple Serotypes of <i>Salmonella</i>

Gene Modulation for Disease Therapy

17.2% of this theme group

Works highlight promising strategies using knockdown, up‑regulation, and apoptosis control to treat disorders.

Downregulation and upregulation (106) · Apoptosis (80) · Gene knockdown (103) · Cell growth (43)

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing <sc

RasGRP3 Promotes RAP1B Activity to Inhibit Endothelial Inflammation and Alleviate Atherosclerosis in High-Fat Diet-Fed ApoE−/− Mice

Functional Plant‑Based Foods and Antioxidants

14.6% of this theme group

Research emphasizes health‑promoting ingredients and sustainable protein sources for modern diets.

Health benefits (78) · Functional food (61) · Ingredient (48) · Antioxidant (69)

Plant-based functional foods for healthy aging: current trends, bioactive compounds, and future perspectives

PLANT-BASED PROTEINS: SOURCES, EXTRACTION METHODS AND FUNCTIONAL PERSPECTIVES FOR THE SUSTAINABLE FOOD INDUSTRY

Epigenetic Editing and RNA‑Based Diagnostics

13.7% of this theme group

Studies present innovative approaches to modify DNA methylation and detect disease‑related RNAs.

Gene (164) · DNA methylation (60) · Messenger RNA (76) · DNA damage (55)

Convergent DNA methylation abnormalities at enhancers and bivalent promoters in human growth disorders

Stimuli-ResponsiveFusion of Binary-Star IntelligentDNA System for the Signal-On Amplification Detection of Cancer-RelatedmiRNA

Novel Antimicrobials and Postbiotic Applications

13.5% of this theme group

Papers describe new plant‑derived agents and microbial metabolites to combat resistance and improve animal health.

Antimicrobial (126) · Antibiotic resistance (66) · Biological pest control (54) · Bacteria (87)

Plants as sources of new antimicrobials and resistance-modifying agents

Postbiotics: Multifunctional Microbial Products Transforming Animal Health and Performance

Genetic Improvement of Crop Yield Traits

11.9% of this theme group

Research showcases advances in trait mapping, QTL analysis, and selection for higher agricultural productivity.

Germplasm (71) · Trait (52) · Quantitative trait locus (40) · Selection (53)

Evaluation of Genetic Variability and Trait Interrelationships Using Advanced Wheat Lines to Increase Yield

GENETIC VARIABILITY ANALYSIS FOR YIELD AND RELATED TRAITS IN WHEAT (TRITICUM AESTIVUM L.) MUTANT GENOTYPES

Sustainable Biomass Conversion and Bioeconomy

11.6% of this theme group

Works highlight microbial fermentation and by‑product valorization as routes to greener fuels and materials.

Biomass (67) · Sustainability (77) · Agriculture (102) · Biofuel (35)

Microbial Fermentation: A Sustainable Strategy for Producing High-Value Bioactive Compounds for Agriculture, Animal Feed, and Human Health

Bioactive Compounds From Agri‐Food By‐Products: Advancements in Environmental Sustainability and Bioeconomic Progress

Tokyo

43.9% across the displayed hubs

4 companies hiring · $525.5M disclosed funding

Kyoto

12.5% across the displayed hubs

0 companies hiring · $245.8M disclosed funding

Chiyoda City

8.6% across the displayed hubs

1 companies hiring · $28.0M disclosed funding

Osaka

8.3% across the displayed hubs

1 companies hiring · $94.9M disclosed funding

Minato City

7.9% across the displayed hubs

0 companies hiring · $190.5M disclosed funding

Bunkyo

7.3% across the displayed hubs

1 companies hiring · $149.6M disclosed funding

Yokohama

5.9% across the displayed hubs

1 companies hiring · $77.6M disclosed funding

Shibuya

5.6% across the displayed hubs

0 companies hiring · $16.6M disclosed funding