Best Enterprise Infrastructure Companies in Chicago, United States
The 171 best Enterprise Infrastructure companies in Chicago, United States in 2026, ranked by funding and momentum. Funding, investors, founders, valuation, tech stack and live signals. Top: Secret Network.
Our analysis of 147 Enterprise Infrastructure companies
$38.8b in tracked funding; 99% of the stack-profiled cohort runs cloud-native; funding activity peaked in 2025.
Ranked: Best Enterprise Infrastructure companies in Chicago
| # | Company | Disclosed funding | Last round | Employees | Founder | Tech stack | Web popularity | Patents & IP focus | Recent signals |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Secret Network Provider of privacy-preserving smart contracts and confidential computing layer for Web3 and AI applications | $412M | 53 mo ago | — | Tor Bair Co-Founder | GitBookNode.jsReact+13 | Top 10M | — | — |
| 2 | Copado 🦄 Provider of DevOps platform for Salesforce releases, testing, and compliance | $329M | 57 mo ago | 700 | Federico Larsen Co-Founder & CTO | WebflowSentryAtlassian Statuspage+28 | Top 1M | 12 patents DevOps pipeline analytics and value‑stream management for software development and delivery | 1 launch |
| 3 | Coro Cybersecurity Threat detection and prevention solution over wifi and cellular networks | $255M | 26 mo ago | 150 | Dror Liwer Co-Founder | WordPressApple iCloud MailMicrosoft 365+48 | Top 5M | — | — |
| 4 | Nerdio 🦄 Nerdio is a software solution provider that empowers Managed Service Providers (MSPs) and enterprise IT… | $127M | 15 mo ago | 121 | Vadim Vladimirskiy Co-Founder & CEO | WordPressSentryZendesk+45 | Top 5M | 18 patents Auto‑scaling virtual desktop infrastructure and standardized cloud IT deployment platforms | 1 award |
| 5 | Fly Platform to build and launch dynamic applications | $115M | 35 mo ago | 35 | Thomas Ptacek Co-Founder | Apple iCloud MailGoogle WorkspaceErlang+14 | Top 100k | — | — |
| 6 | Cleversafe Hybrid data storage technologies | $103M | 152 mo ago | 211 | — | — | — | 1,310 patents Secure erasure-coded distributed storage with indexed metadata and efficient slice migration | — |
| 7 | springcm SpringCM is a secure document and contract management platform used to solve critical business needs. | $80M | 95 mo ago | 177 | — | — | — | — | — |
| 8 | Fingerprint Provider of device intelligence platform identifying web visitors and mobile devices | $77M | 33 mo ago | 112 | Valentin V Co-Founder & CTO | ReadMeZendeskApple iCloud Mail+26 | Top 1M | — | — |
| 9 | Adeptia Cloud based data integration platform for enterprises | $65M | 38 mo ago | 20 | Charles Nardi CEO | SanityApple iCloud MailGoogle Workspace+29 | Top 10M | — | — |
| 10 | Keeper Security Offers web-based password manager solutions | $60M | 37 mo ago | 331 | Craig Lurey CTO | Apple iCloud MailGoogle WorkspaceMaterial Design Lite+28 | Top 100k | — | 1 launch · 1 award |
| 11 | Trustwave Provider of cybersecurity suite solutions | $60M | 146 mo ago | 1,254 | — | HubSpot CMS HubApple iCloud MailTailwind CSS+19 | Top 500k | 70 patents Automated cyber incident response, threat hunting, and network security analytics platforms | — |
| 12 | Narrative Science Provider of an AI-based content creation solution | $48M | 110 mo ago | 64 | — | — | — | — | — |
| 13 | NowSecure Mobile application security solutions provider | $28M | 48 mo ago | 83 83 → 103 (+24%) | Andrew Hoog Founder/Board Member | WordPressApple iCloud MailGoogle Workspace+30 | Top 5M | — | 1 launch |
| 14 | SingleHop Managed cloud infrastructure for SMBs | $28M | 145 mo ago | 146 | — | — | — | — | — |
| 15 | MetalSoft Developer of bare metal automation software for infrastructure management solutions | $16M | 42 mo ago | 25 | — | WixSentryZendesk+19 | Top 50M | — | 1 launch |
| 16 | K4 Mobility Provider of maritime communication solutions | $15M | 36 mo ago | 31 | Michael Small Co-Founder & CEO | ZohoMUIEnvoy+9 | Top 10M | 5,673 patents Patents concentrated in electrical & electronics | — |
| 17 | Inxpo Enterprise video communication solution | $14M | 100 mo ago | 115 | — | — | — | 5 patents Patents concentrated in computing, sensing & instrumentation | — |
| 18 | oak9 Provider of cloud and devops security solutions | $14M | 47 mo ago | 50 | Aakash Shah CTO | — | — | — | — |
| 19 | Empirical Security Provider of AI model security solutions | $12M | 21 mo ago | — | Michael Roytman Co-Founder & CTO | SanityNode.jsReact+15 | Top 50M | — | 2 launchs |
| 20 | Open Kernel Labs Software to secure wireless communications, applications and content for mobile devices | $10M | 167 mo ago | — | — | — | — | — | — |
| 21 | Neurensic Regulatory compliance using Artificial Intelligence | $9M | 111 mo ago | 186 | — | — | — | — | — |
| 22 | Compliance11 Compliance software for financial services | $7M | 182 mo ago | 26 | Tad Mitchell Ex-President & CEO | — | — | — | — |
| 23 | Mesh++ Provider of solar powered mesh networking nodes | $5M | 59 mo ago | 11 | — | ShopifyGoogle MapsUbuntu+20 | Top 50M | — | — |
| 24 | NexLP Provider of a cloud based text analytics solution | $5M | 103 mo ago | 10 | — | — | — | — | — |
| 25 | Rippleshot Provider of AI-driven banking fraud analytics and detection platform solutions | $5M | 94 mo ago | 10 10 → 13 (+30%) | Yueyu Fu Co-Founder | Webflowcore-jsSwiper+16 | Top 50M | — | — |
| 26 | ThirdPartyTrust SaaS solution for security and vendor risk management | $5M | 77 mo ago | 59 | — | — | — | — | — |
| 27 | Parlano Team collaboration and messaging platform | $4M | 260 mo ago | 11 | — | — | — | 11 patents Real-time enterprise information flow and collaborative workflow management platforms | — |
| 28 | AutoCloud Provider of infrastructure as a code solution | $4M | 30 mo ago | 7 | Christopher Koning Founder | Chief Technology Officer | — | — | — | — |
| 29 | Cog Systems Virtualization & system hardening based embeddable IoT security | $4M | 90 mo ago | 18 | Laura McCann-Nerup Co-Founder | — | — | — | — |
| 30 | Cohesive Networks Cloud networking and security products | $3M | 228 mo ago | 18 | Patrick Kerpan CEO | — | — | — | — |
| 31 | Winston Privacy Provider of VPN solutions for protection from spying and identity theft | $3M | 77 mo ago | 9 | — | — | — | 12 patents Network security and privacy enforcement through endpoint identification and rate‑limiting mechanisms | — |
| 32 | Eta Vision Offers data center energy management solutions | $2M | 95 mo ago | 8 | Michael Lingle CEO & Cofounder | — | — | — | — |
| 33 | quicklaunchsso.com SSO application for one-click login to enterprise apps across multiple devices | $2M | 141 mo ago | — | Katie Winings Founder | JavaBootstrapApache Tomcat+8 | Top 5M | — | — |
| 34 | MobileX Labs EarnPhone revolutionizing smartphones, rewarding users for everyday activities with proprietary software | $2M | 143 mo ago | — | Daniel Novaes Co-Founder & CEO | — | — | — | — |
| 35 | Moonshado Mobile Messaging Aggregator | $1M | 177 mo ago | — | Patty Mayer Founder | — | — | — | — |
| 36 | CloudRanger Automated backups, disaster recovery and server management for Amazon EC2 | $1M | 104 mo ago | 20 | — | — | — | — | — |
| 37 | MessageControl Email security and anti-spymail solution | $1M | — | 16 | Paul Everton Founder | — | — | — | — |
| 38 | Parallel Works HPC Platform to run Compute intensive simulations and build workflow jobs in parallel | $500K | 76 mo ago | 9 | Matthew Shaxted Co-Founder & President | WordPressMySQLPHP+27 | Top 10M | — | 1 launch |
| 39 | Draftbit Visual mobile app development tool | $150K | 82 mo ago | 12 | Peter Piekarczyk Co-Founder & Advisor | WebflowStripeAtlassian Statuspage+23 | Top 5M | — | 1 launch |
| 40 | Genuity IT management software suite | $125K | 57 mo ago | 21 | Colum Donahue Co-Founder & CEO | Vue.jsAmazon Web ServicesCloudflare+24 | Top 10M | 11 patents Advanced VoIP routing, QoS monitoring, and security for packet-based voice communications | — |
| 41 | HACKERverse Provider of software tools for cybersecurity testing | $120K | 24 mo ago | — | Craig Ellrod Founder & CTO | — | — | — | — |
Top 12 Enterprise Infrastructure companies in Chicago
#1
Nerdio 🦄Series C · Chicago, Illinois · founded 2005 · 121 employees$127.4Mraised▾
Nerdio is a software solution provider that helps organizations deploy, manage, and optimize virtual desktops in Microsoft Azure. The company offers a range of products and services, including Nerdio Manager for Enterprise and Nerdio Manager for MSP, which provide cost-effective and efficient management of virtual desktop environments. With Nerdio, organizations can streamline their virtual desktop deployments, reduce costs, and improve user experience.
- Mar 2025Series C$500M
- Dec 2022Series B$117M
- Feb 2020Series A$8M
- Feb 2014Series A$2.4M
#2
Series D · Chicago, Illinois · founded 2014 · 150 employees$255Mraised▾
Threat detection and prevention solution over wifi and cellular networks. The platform offers software that detects, and analyzes in real time any threats or attacks that are present in the vicinity of the device, and prevent the device from connecting to the malicious cellular or Wifi Access points. Its offline learning machine uses the collected data from the devices, publicly available data, and data from the attack lab to construct the algorithms that the client software uses. The dashboard helps to define key field behaviors, roles and responses and to visualize the current threat levels, by geography, device, or role on a real time threat map.
- Mar 2024Series D$100M
- Apr 2023Series C$75M
- Jul 2022Series C—
- Apr 2022Series C$80M
#3
Series B · Chicago, Illinois · founded 2024$11.9Mraised▾
Provider of AI model security solutions. It is a provider of cyber security solutions that utilize mathematical models to analyze and optimize security data, enabling organizations to proactively anticipate and prevent security threats.
- Aug 2024Series B$11.9M
#4
Series C · Chicago, Illinois · founded 2016 · 35 employees$115Mraised▾
Fly is a platform to build and launch dynamic applications for users around the world. The platform acts as a global load balancer, a reverse proxy, and a library of Middleware. With the Fly platform, clients can attach and swap around, containers, Heroku applications, GitHub Pages, Kubernetes clusters, third-party services, and serverless functions without any downtime. Other features include routing, automatic renewal of SSL certificates, and DNS.
- Jun 2023Series C$70M
- Jul 2022Series B$25M
- Aug 2021Series A$12M
- 2020Seed$125K
#5
Series C · Chicago, Illinois · founded 2019 · 112 employees$77Mraised▾
Provider of device intelligence platform identifying web visitors and mobile devices. The platform helps determine user intentions, identify good and bad visitors, and stop fraud. It offers account takeover prevention, payment fraud reduction, and SMS fraud prevention. The platform also detects malicious bots and automation tools. It provides signals for VPN detection, IP geolocation, and browser bot detection.
- Sep 2023Series C$33M
- Nov 2021Series B$32M
- Feb 2021Series A$8M
- Oct 2020Series A$4M
#6
Copado 🦄Series C · Chicago, Illinois · founded 2013 · 700 employees$328.8Mraised▾
Provider of DevOps platform for Salesforce releases, testing, and compliance. The platform offers continuous integration and delivery, robotic testing, and artificial intelligence to streamline software development lifecycles. It provides tools for planning, building, testing, releasing, and operating Salesforce applications. The platform supports various team roles, including administrators, architects, developers, and testers, across multiple industries.
- Sep 2021Series C$140M
- Aug 2021Series C$52.8M
- Jul 2021Series B$5.2M
- Feb 2021Series B$96M
#7
Series C · Chicago, Illinois · founded 2020$411.5Mraised▾
Provider of privacy-preserving smart contracts and confidential computing layer for Web3 and AI applications. It provides first mainnet blockchain with end-to-end encrypted smart contracts, enabling decentralized apps with institutional-grade data privacy through Trusted Execution Environments (TEE). It serves as Web3's confidential computing hub, supporting private tokens, bridges for token privacy across chains, scalable DeCC infrastructure, and emerging Secret AI layer for secure GPU/LLM workloads—featuring Merkle proofs, threshold encryption, EVM interoperability, and Cosmos SDK upgrades for cross-chain privacy applications.
- Jan 2022Series C$400M
- May 2021Series B$11.5M
#8
Series D · Chicago, Illinois · founded 2009 · 331 employees$60Mraised▾
Offers web-based password manager solutions. It develops a mobile app that helps consumers to protect and manage their passwords and private information. The app uses military-grade advanced encryption standards, key storage, double-encrypted syncing, and two-factor authentication. It also features an admin console for managing keeper group users, devices, and permissions.
- May 2023Series D—
- Aug 2020Series C$60M
#9
Series C · Chicago, Illinois · founded 2000 · 20 employees$65Mraised▾
Cloud based data integration platform for enterprises. It leverages AI that enables users to create a cloud to cloud business integrations using data exchange and mapping, data transformation, and data integration with customers, partners, and suppliers. Features include monitoring data performance, dashboard analytics, information templates, a centralized message center, data protocols, and more.
- Mar 2023Series C$65M
#10
Series A · Chicago, Illinois · founded 2018 · 31 employees$15.3Mraised▾
Developer of a proprietary digital platform intended to offer internet technologies to maritime users. The company's platform uses software algorithms to select the optimum networks among the satellites and terrestrial options available to provide simple, reliable, and powerful internet, enabling clients with reliable internet service in ships both in port and the deep sea.
#11
Deadpooled · Chicago, Illinois · founded 2019 · 7 employees$4Mraised▾
Provider of infrastructure as a code solution. The platform automatically generates infrastructure as a code. It offers a list of resources and configurations across different environments. It provides a cloud asset change tracking and notification feature that creates snapshots of the infrastructure to understand the changes in the environment.
- Nov 2023Seed—
- Nov 2021Seed$4M
- Jan 2021Seed—
#12
Series B · Chicago, Illinois · founded 2009 · 83 employees$27.5Mraised▾
NowSecure is a mobile application security solutions provider. It provides BYOD security for the enterprise and provides risk ratings at the device and group levels, offers push notifications of new risks in real-time. It also provides analytic engines that are fully customizable and deployable on-prem or as a cloud model. It also provides an app testing suite for developers, and a mobile security app for consumers to keep their mobile device and data secure. The clients of the company include Uber, Robot, Humana, Rakuten, etc.
- Jun 2022Conventional Debt—
- Jun 2019Series B$15M
- Dec 2014Series A$12.5M
- Aug 2014Seed—
Funding & investor landscape
Notable founders
Market landscape — 10 sub-themes by coverage
Share of Enterprise Infrastructure coverage by sub-theme.
Regulatory-risk over time rising
Funding & growth over time
funding rising · growth rising
How research on Cloud Computing in Chicago is moving
A read on the academic research around Cloud Computing in Chicago — which themes are gaining ground, the institutions and researchers driving them, and how the tone is shifting. Based on 61 papers.
University of Chicago and its peers lead Chicago's cloud-computing research, focusing on resource management and distributed systems, with breakthroughs and advancements dominating an optimistic but moderately cautious field.
- University of Chicago30
- University of Illinois Chicago21
- Chicago State University5
- Loyola University Chicago4
- Chicago Anesthesia Pain Specialists3
- Resource (disambiguation)4
- Edge computing3
- Scalability3
- Key (lock)3
- Scheduling (production processes)3
- Scale (ratio)5
- Key (lock)5
- Matching (statistics)4
- Distributed computing3
- Operating system3
- Internet privacy4
- Data science3
- World Wide Web2
- Big data2
- Outsourcing1